Determining the mechanism of Shuxuening injection against liver cirrhosis through network pharmacology and animal experiments by Qiyao Liu, Tingyu Zhang, Yongan Ye, Xin Sun, Huan Xia, Xu Cao, Xiaoke Li, Wenying Qi, Yue Chen, Xiaobin Zao

“…Enrichment analysis showed that these genes were associated with cancer-related pathways, including phosphoinositide-3-kinase/Akt and mitogen-activated protein kinase signaling and various cellular processes, such as responses to chemicals and metabolic regulation. …”
Get full text

Exosomes Play an Important Role in the Progression of Plasma Cell Mastitis via the PI3K-Akt-mTOR Signaling Pathway by Xiaohong Wang, Yong Han, Jian Liu, Yingzhe Zhang, Kai Cheng, Jiwei Guo, Qingqun Guo, Song Liu, Hongguang Sun, Yitong Hua, Guoqiang Zhang, Shujian Xu, Fengli Guo, Zhenlin Yang

Get full text

Contextual adaptation of digital wellbeing interventions for young people: insights from a project in Saudi Arabia by Dahlia Aljuboori, Laura K. Clary, Saud Abdulaziz Alomairah, Saud Abdulaziz Alomairah, Michelle Colder Carras, Nazmus Saquib, Juliann Saquib, Fahad Albeyahi, Antonius J. Van Rooij, Anouk Tuijnman, Vincent G. Van der Rijst, Michelle R. Kaufman, Michelle R. Kaufman, Johannes Thrul, Johannes Thrul, Johannes Thrul

Get full text

Natural sources, refined extraction, biosynthesis, metabolism, and bioactivities of dietary polymethoxyflavones (PMFs) by Renyou Gan, Yi Liu, Hang Li, Yu Xia, Huan Guo, Fang Geng, Qiguo Zhuang, Huabin Li, Dingtao Wu

“…PMFs have received increasing attention due to their multiple bioactivities, such as antioxidant, anti-inflammatory, anti-cancer, metabolic regulatory, immunoregulatory, neuroprotective, and skin protective effects. …”
Get full text

Complicaciones en la cirugía ginecológica by Sara Amneris Urgellés Carreras, Maritza Álvarez Fiallo, Vilvia Ramos Zamora, Enrique Reyes Guerrero, Odalys Acosta León

“…Ambas están determinadas por factores de riesgo como la edad, enfermedad médica preexistente, obesidad, cirugías previas, anemia y cáncer. Objetivo: Determinar las principales complicaciones, su asociación con el diagnóstico preoperatorio, el tipo de operación realizada y la comorbilidad en pacientes intervenidas por afecciones ginecológicas. …”
Get full text

An Experimental Intervention Study Assessing the Impact of a Thin Silicone Gel Surface Overlay on Interface Pressure by Seth Kwadjo Angmorterh, Andrew England, Sonia Aboagye, Eric Kwasi Ofori, Peter Hogg

“…The incidence of pressure ulcers (PUs) presents a substantial threat to patients, especially geriatric patients, those with restricted mobility, and patients suffering from chronic diseases such as cancer. PUs creates a huge financial burden on healthcare authorities and patients, costing billions to treat and manage. …”
Get full text

LncRNA GAS5 inhibits glioma progression through miR-135b-5p/APC axis by ZHANG Jidong, WANG Yutao, JI Jianwen

“…Western blotting and qRT-PCR indicated that GAS5 was down-regulated in the glioma cell lines and tissues than human normal astrocytes and para-cancer tissues (P<0.01). The results of CCK-8, Transwell and wound healing assays revealed that overexpression of GAS5 significantly inhibited the viability, invasion and migration abilities in T98 cells when compared with the cells of the vector group (P<0.01). …”
Get full text

Etiology of Ascites and Pleural Effusion Associated with Ovarian Tumors: Literature Review and Case Reports of Three Ovarian Tumors Presenting with Massive Ascites, but without Per... by Ai Miyoshi, Takashi Miyatake, Takeya Hara, Asuka Tanaka, Naoko Komura, Shinnosuke Komiya, Serika Kanao, Masumi Takeda, Mayuko Mimura, Masaaki Nagamatsu, Takeshi Yokoi

“…Borderline ovarian tumors are benign but relatively large tumors that are often initially mistaken as ovarian cancers. We report three cases of stage I borderline ovarian tumors having massive ascites that we (preoperatively) suspected of being advanced ovarian cancer. …”
Get full text

Muscle contractile properties and perceived fatigue in the general and diseased population by Isa H. Mast, Neeltje A. E. Allard, Dominique tenHaaf, Anouk A. F. Stoffels, Lando Janssen, Hieronymus W. H. vanHees, Silvie Timmers, Bregina T. P. Hijmans‐Kersten, Maria T. E. Hopman, Laurien M. Buffart

“…We pooled data on perceived fatigue, physical fitness, and contractile properties from six studies, including a control group (n = 90), cancer survivors (n = 27), patients with chronic obstructive pulmonary disease (COPD; n = 16), chronic myeloid leukemia (CML; n = 20), and statin users (n = 64). …”
Get full text

Natural pigments: innovative extraction technologies and their potential application in health and food industries by Ayu Masyita, Gemala Hardinasinta, Ayun Dwi Astuti, Firdayani Firdayani, Dian Mayasari, Aki Hori, Ira Nur Ainun Nisha, Firzan Nainu, Takayuki Kuraishi

“…For example, delphinidin (30 µM) significantly inhibited the growth of three cancer cell lines (B16-F10, EO771, and RM1) by at least 90% after 48 h. …”
Get full text

Validation of a Novel Immunoline Assay for Patient Stratification according to Virulence of the Infecting Helicobacter pylori Strain and Eradication Status by Luca Formichella, Laura Romberg, Hannelore Meyer, Christian Bolz, Michael Vieth, Michael Geppert, Gereon Göttner, Christina Nölting, Wolfgang Schepp, Arne Schneider, Kurt Ulm, Petra Wolf, Ingrid Lisanne Holster, Ernst J. Kuipers, Bernd Birkner, Erwin Soutschek, Markus Gerhard

“…In addition, a high recomLine score was significantly associated with high-grade gastritis, atrophy, intestinal metaplasia, and gastric cancer. Thus, the recomLine is a sensitive and specific noninvasive test for detecting serum responses against H. pylori in actively infected and eradicated individuals. …”
Get full text

Colorectal Serrated Neoplasia: An Institutional 12-Year Review Highlights the Impact of a Screening Programme by A. J. McCarthy, S. M. O’Reilly, J. Shanley, R. Geraghty, E. J. Ryan, G. Cullen, K. Sheahan

“…Detection of SSL/Ps peaked in the most recent years reviewed (87.5% reported between 2013 and 2016, inclusive), coinciding with the introduction of “BowelScreen” (the Irish FIT-based colorectal cancer screening programme). Conclusions. Awareness of, and adherence to, diagnostic criteria is essential for accurate classification of colorectal polyps.…”
Get full text

Effectiveness of nurse-led care in patients with rheumatoid arthritis: a systematic review and meta-analysis by Dan Liu, Li Liu, Lin Yang, Ting Wen, Peng Xiang, Guifang Pi

Get full text

Cardiovascular Profile and Cardiovascular Imaging After Bariatric Surgery: A Narrative Review by Mihaela Toader, Liliana Gheorghe, Costin Chirica, Ionuț-Alexandru Ghicu, Sabina-Ioana Chirica, Andreea Isabela Mazga, Danisia Haba, Mădălina Maxim, Ancuța Andreea Miler, Daniela Crișu, Mihai Ștefan Cristian Haba, Daniel Vasile Timofte

“…Additionally, obesity contributes to an increased probability of developing certain types of cancer, osteoarthritis, urinary incontinence, and chronic kidney disease. …”
Get full text

Aflatoxins in Uganda: An Encyclopedic Review of the Etiology, Epidemiology, Detection, Quantification, Exposure Assessment, Reduction, and Control by Timothy Omara, Winfred Nassazi, Tom Omute, Aburu Awath, Fortunate Laker, Raymond Kalukusu, Bashir Musau, Brenda Victoria Nakabuye, Sarah Kagoya, George Otim, Eddie Adupa

“…More efforts should be geared towards awareness creation and vaccination against hepatitis B and hepatitis A to reduce the risk of development of liver cancer among the populace.…”
Get full text

GV1001, hTERT Peptide Fragment, Prevents Doxorubicin-Induced Endothelial-to-Mesenchymal Transition in Human Endothelial Cells and Atherosclerosis in Mice by Wei Chen, Seojin Kim, Sharon Y. Kim, Cheyenne Beheshtian, Naryung Kim, Ki-Hyuk Shin, Reuben H. Kim, Sangjae Kim, No-Hee Park

“…GV1001, a multifunctional peptide with anti-inflammatory, anti-cancer, antioxidant, and anti-Alzheimer’s properties, has demonstrated inhibition of EndMT. …”
Get full text

Role and sensitivity of Positron Emission Tomography with [18F]Fluorodeoxyglucose in diagnosis and follow-up of patients affected by chronic pulmonary aspergillosis (CPA) by Gianfranco Schiraldi, Cristina Elena Popescu, Michele Chiericozzi, Salvatore Lo Cicero, Flavio Allegri, Franco Mosca, Claudio Rossetti

Get full text

On the Biosynthesis of Bioactive Tryptamines in Black Cohosh (<i>Actaea racemosa</i> L.) by Martin J. Spiering, James F. Parsons, Edward Eisenstein

“…., Ranunculaceae) is a multicomponent botanical therapeutic used as a popular remedy for menopause and dysmenorrhea and explored as a treatment in breast and prostate cancer. However, its use and safety are controversial. …”
Get full text

Providing medically tailored groceries and food resource coaching through the charitable food system to patients of a safety-net clinic in Dallas, Texas: a randomised controlled tr... by Michael Bowen, Sandi L Pruitt, Jaclyn Albin, Tammy Leonard, Willis Wong, Milette Siler, Carolyn Haskins, Jessica Turcios, Carla Pezzia, Alisha Ford, Bianca Schinzer, Kelseanna Hollis-Hansen

Get full text

Health-Related Quality of Life, Treatment Satisfaction, Adherence and Persistence in β-Thalassemia and Myelodysplastic Syndrome Patients with Iron Overload Receiving Deferasirox: R... by John Porter, Donald K. Bowden, Marina Economou, Jacques Troncy, Arnold Ganser, Dany Habr, Nicolas Martin, Adam Gater, Diana Rofail, Linda Abetz-Webb, Helen Lau, Maria Domenica Cappellini

Get full text