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Pharmacological activities and phytochemical evaluation of coconut crude oil and upon exposure to ozone
Published 2025-01-01“…Some biological tests were done including antibacterial action versus Helicobacter pylori, anti-biofilm activity versus H. pylori, anti-hemolytic activity in the existence of H. pylori, anti-Alzheimer action, and cytotoxic effect towards A-413 cancer cell line to determine the activity of coconut oil and upon exposure to ozone. …”
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Increased Expression of VEGF and CD31 in Postradiation Rectal Tissue: Implications for Radiation Proctitis
Published 2013-01-01“…Rectal mucosa biopsies from 11 patients who underwent irradiation for prostate cancer were examined immunohistochemically for the expression of VEGF and CD31 at three time settings—before, at the completion of, and 6 months after radiotherapy. …”
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15748
Green Synthesis of Antibacterial CuO Nanoparticles Based on the Synergy Between <i>Cornu aspersum</i> Snail Mucus and Ascorbic Acid
Published 2025-01-01“…Many biologically active compounds have been identified in the mucus of the garden snail <i>Cornu aspersum</i>, which are effective in the treatment of several diseases such as cancer, ulcers, wounds, etc. The incorporation of these compounds into the green synthesis of copper nanoparticles (CuONPs-Muc) was demonstrated in our previous study. …”
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15749
Scutellarein Inhibits Osteosarcoma Growth by Targeting the TLR4/TRAF6/NF-κB Pathway
Published 2025-01-01“…Scutellarein (SCU) is a monomeric flavone bioactive compound with potent anti-cancer activity. However, the effects and mechanisms of SCU on the growth of OS remain unknown.Methods: The Cell Counting Kit-8, colony formation assay and 5-ethynyl-2′-deoxyuridine (EdU) incorporation assays were used to analyze cell proliferation ability in vitro. …”
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15750
Development and experimental validation of dephosphorylation-related biomarkers to assess prognosis and immunotherapeutic response in gliomas
Published 2025-01-01“…This study aims to construct a validated prognostic risk model for dephosphorylation, which will provide new directions for clinical treatment, prognostic assessment, and temozolomide (TMZ) resistance in glioma patients.MethodsScreening dephosphorylation-related genes (DRGs) and transcriptome expression data from The Cancer Genome Atlas (TCGA), Molecular signatures database (MSigDB) and constructing risk scoring models. …”
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15751
Reproducibility and repeatability of 18F-(2S, 4R)-4-fluoroglutamine PET imaging in preclinical oncology models.
Published 2025-01-01“…<h4>Methods</h4>Twenty mice bearing colorectal cancer cell line xenografts were injected with ~9 MBq of 18F-Gln and imaged in an Inveon microPET. …”
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Exploring the Anti-depression Mechanism of Polygonatum ordoratum Based on GEO Database Combined with Network Pharmacology and Molecular Docking Technology
Published 2025-01-01“…A total of 209 GO entries were obtained through GO enrichment analysis, including 149 biological processes (BP), 23 cellular components (CC), and 37 molecular functions (MF), primarily involving the Chemical carcinogenesis-receptor activation, Small cell lung cancer, and Adipocytokine signaling pathway. Molecular docking analysis revealed that the main active components of Yuzhu exhibited high docking stability with major targets of depression. …”
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15754
Global, regional and national epidemiological trends of multiple myeloma from 1990 to 2021: a systematic analysis of the Global Burden of Disease study 2021
Published 2025-01-01“…Known epidemiological data suggest that MM accounts for approximately 10% of all hematologic malignancies and remains the second most common hematologic cancer worldwide. This study utilized data from the 2021 Global Burden of Diseases (GBD) study to evaluate the prevalence, incidence, mortality, disability-adjusted life years (DALYs), and attributable risk factors of MM from 1990 to 2021, and to project future trends for the next 15 years.MethodsGBD 2021 data were analyzed to assess MM’s global burden using four key epidemiological measures: prevalence, incidence, mortality, and DALYs. …”
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The new HFA/ICOS risk assessment tool to identify patients with chronic myeloid leukaemia at high risk of cardiotoxicity
Published 2022-06-01“…So far, the Systematic Coronary Risk Evaluation (SCORE) charts of the European Society of Cardiology (ESC) have been used to identify cancer patients at increased cardiovascular risk. …”
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TransRAUNet: A Deep Neural Network with Reverse Attention Module Using HU Windowing Augmentation for Robust Liver Vessel Segmentation in Full Resolution of CT Images
Published 2025-01-01“…<b>Background:</b> Liver cancer has a high mortality rate worldwide, and clinicians segment liver vessels in CT images before surgical procedures. …”
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Comparison of ZnS(Ag) Scintillator and Proportional Counter Tube for Alpha Detection in Thin-Layer Chromatography
Published 2024-12-01“…(1) <b>Background</b>: Targeted alpha therapy is an emerging field in nuclear medicine driven by two advantages: overcoming resistance in cancer-suffering patients to beta therapies and the practical application of lower activities of <sup>212</sup>Pb- and <sup>225</sup>Ac-labelled peptides to achieve the same doses compared to beta therapy due to the highly cytotoxic nature of alpha particles. …”
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The validation and cross-cultural adaptation of the PainDETECT questionnaire in osteoarthritis-related pain
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