Factors associated with in-hospital mortality in octogenarians managed by geriatric service in a referral hospital in Colombia by Carlos Mario Cortes Bahamon, Jenny Rodríguez Ángel, Jennifer Katherine Ballesteros Tapias, Diego Andrés Chavarro-Carvajal, Oscar Mauricio Muñoz

“…Factors independently associated with mortality were history of cancer (Odds ratio (OR): 2.31; 95% Confidence interval (CI): 1.34–3.98, p  < 0.003), delirium (OR: 2.48; 95% CI: 1.44–4.28, p  < 0.001), malnutrition (OR: 2.50; 95% CI: 1.46–4.28; p  = 0.001), frailty (OR: 2.25; 95% CI: 1.13–4.45, p  = 0.019), tachypnea on admission (OR: 1.09; 95% CI: 1.03–1.14, p  = 0.002), and creatinine elevation (OR: 2.47; 95% CI: 1.47–4.15, p  = 0.001). …”
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Inhibition of Corneal Neovascularization by Subconjunctival Injection of Fc-Endostatin, a Novel Inhibitor of Angiogenesis by Junko Yoshida, Robert T. Wicks, Andrea I. Zambrano, Betty M. Tyler, Kashi Javaherian, Rachel Grossman, Yassine J. Daoud, Peter Gehlbach, Henry Brem, Walter J. Stark

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Triplet Electron Exchange in Carbon Nanodots‐assisted Long‐persistent near‐infrared Chemiluminescence for Oncology Synergistic Imaging and Therapy by Run‐Wei Song, Tian‐Ci Jiang, Xue‐Yang Zhang, Cheng‐Long Shen, Qing Lou, Chong‐Xin Shan

“…Mechanistically, the excess reactive oxygen species in TME can trigger the chemically initiated singlet/triplet electron exchange between the hydrophobic CDs‐Ce6 and peroxalate‐derived 1,2‐dioxetanes and thus the excess excited singlet/triplet electron of the CDs‐Ce6 can ensure the long‐persistent near‐infrared CL, type I/II photochemical production of hydroxyl radicals, superoxide radical and singlet oxygen, and type III photochemical damage of maladjusted biomacromolecules, enabling the long‐persistent near‐infrared biological imaging and enhanced cancer therapy. These results shed a new sight into the energy transfer mechanism in chemiluminescence and pave a new sight into the architecture of multifunctional theragnostic nanoplatforms.…”
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Radiation decreases bronchial epithelial progenitor function as assessed by organoid formation by Merian E. Kuipers, Dennis K. Ninaber, Krista C.J. van Doorn-Wink, Annelies M. Slats, Pieter S. Hiemstra

“…Abstract Objective Radiation-induced lung injury (RILI) is a serious side-effect of radiotherapy for lung cancer, in which effects on the normal lung epithelium may play a key role. …”
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Three-Dimensional Reconstruction of Oral Tongue Squamous Cell Carcinoma at Invasion Front by Tomoo Kudo, Yoshihito Shimazu, Hisao Yagishita, Toshiyuki Izumo, Yuuichi Soeno, Kaori Sato, Yuji Taya, Takaaki Aoba

“…Based on a pathodiagnostic survey of whole cancer lesions, a core tissue specimen (3 mm in diameter) was dissected out from the deep invasion front using a paraffin tissue microarray. …”
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Adherence to the ISHLT Protocol for the Referral of Patients with Idiopathic Pulmonary Fibrosis to the Transplantation Center among of Czech Centers for Interstitial Lung Diseases by Martina Sterclova, Martina Doubkova, Lubica Sykorova, Vladimir Bartos, Monika Zurkova, Vladimira Lostakova, Radka Mokosova, Martina Plackova, Ladislav Lacina, Michaela Cimrova, Radka Bittenglova, Pavlina Lisa, Pavla Musilova, Daniel Dolezal, Jana Psikalova, Petra Ovesna, Martina Koziar Vasakova

“…Patients with a history of cancer <5 years from the time of IPF diagnosis, patients with alcohol abuse, and patients with an accumulation of vascular comorbidities were excluded. …”
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Comparison of User-Directed and Automatic Mapping of the Planned Isocenter to Treatment Space for Prostate IGRT by Zijie Xu, Ronald Chen, Andrew Wang, Andrea Kress, Mark Foskey, An Qin, Timothy Cullip, Gregg Tracton, Sha Chang, Joel Tepper, Di Yan, Edward Chaney

“…The purpose of this study was to retrospectively compare a fully automatic approach, including a non-rigid step, against a user-directed rigid method implemented in a clinical IGRT protocol for prostate cancer. Isocenters resulting from automatic and clinical mappings were compared to reference isocenters carefully determined in each tCT. …”
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Nursing of a patient with chemotherapy-induced oral ulcer treated with Traditional Chinese Medicine mouthwash combined with moxibustion (中药含漱疗法联合艾灸治疗化疗相关性口腔溃疡1例的护理)... by LI Fang (李芳), LIU Shuhong (刘书红), ZHAO Yanan (赵亚楠), ZHAO Yan (赵燕)

“…To summarize the nursing of a liver cancer patient with chemotherapy-induced oral ulcer, and provide reference for clinical practice. …”
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The Essential Role of Monte Carlo Simulations for Lung Dosimetry in Liver Radioembolization—Part B: ¹⁶⁶Ho Microspheres by Edoardo d’Andrea, Andrea Politano, Bartolomeo Cassano, Nico Lanconelli, Marta Cremonesi, Vincenzo Patera, Massimiliano Pacilio

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Cryo-Imaging and Software Platform for Analysis of Molecular MR Imaging of Micrometastases by Mohammed Q. Qutaish, Zhuxian Zhou, David Prabhu, Yiqiao Liu, Mallory R. Busso, Donna Izadnegahdar, Madhusudhana Gargesha, Hong Lu, Zheng-Rong Lu, David L. Wilson

“…This mouse-to-cells multiscale and multimodality platform should uniquely enable more informative and accurate studies of metastatic cancer imaging and therapy.…”
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Gene mutation, clinical characteristics and pathology in resectable lung adenocarcinoma by Ji’an Zou, Wei Han, Yan Hu, Chao Zeng, Jina Li, Weixuan Lei, Jieming Cao, Quanming Fei, Mengqi Shao, Junqi Yi, Zeyu Cheng, Li Wang, Fang Wu, Wenliang Liu

“…Abstract Objective With the wide use of CT scan in clinical practice, more lung cancer was diagnosed in resectable stage. Pathological examination and genetic testing have become a routine procedure for lung adenocarcinoma following radical resection. …”
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Lymphopenia Is Associated with Gross Target Volumes and Fractions in Hepatocellular Carcinoma Patients Treated with External Beam Radiation Therapy and Also Indicates Worse Overall... by Hai-Ge Zhang, Ping Yang, Tao Jiang, Jian-Ying Zhang, Xue-Juan Jin, Yong Hu, Jing Sun, Shi-Suo Du, Zhao-Chong Zeng

“…Lymphocyte nadir and Barcelona Clinic Liver Cancer (BCLC) stage were independent prognostic factors predicting OS of HCC patients (all p<0.001). …”
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cfDNA as a surrogate marker for COVID-19 severity in patients with influenza-like symptoms with and without SARS-CoV-2 infections in general practice: a study protocol for a prospe... by Dorothea Dehnen, Elmo Neuberger, Jürgen in der Schmitten, Ekaterini Giagkou, Perikles Simon, Suzan Botzenhardt

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Single-cell sequencing reveals cell heterogeneity and aberrantly activated pathways associated with microvascular invasion in hepatocellular carcinoma by Jianwei Cui, Fanyi Zeng, Ming Tang, Ming Tang, Shiwu Yin, Shiwu Yin

“…IntroductionHepatocellular carcinoma (HCC) is the most common primary liver cancer, with microvascular invasion (MVI) identified as a major predictor of early recurrence. …”
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Antibiofilm and Anticancer Activity of Multi-Walled Carbon Nanotubes Fabricated with Hot-Melt Extruded Astaxanthin-Mediated Synthesized Silver Nanoparticles by You HS, Jang YS, Sathiyaseelan A, Ryu SJ, Lee HY, Baek JS

“…MWCNT-AST showed higher anticancer activity against breast cancer cells (MDA-MB-231) than MWCNT-Ag, and lower toxicity in normal cells HaCaT and NIH3T3.Conclusion: MWCNT-AST exhibits higher antioxidant, antibiofilm, and anticancer activities than MWCNT-Ag, and exhibits lower toxicity to normal cells. …”
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Validation of Mortality Data Sources Compared to the National Death Index in the Healthcare Integrated Research Database by Jamal-Allial A, Sponholtz T, Vojjala SK, Paullin M, Papazian A, Eshete B, Mahmoudpour SH, Verpillat P, Beachler DC

“…This validation study assesses the accuracy of various mortality data sources with the NDI.Methods: This validation study is a secondary analysis of an advanced cancer cohort in the US between January 2010 and December 2018, with an established NDI linkage. …”
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High-throughput fluorescence lifetime imaging flow cytometry by Hiroshi Kanno, Kotaro Hiramatsu, Hideharu Mikami, Atsushi Nakayashiki, Shota Yamashita, Arata Nagai, Kohki Okabe, Fan Li, Fei Yin, Keita Tominaga, Omer Faruk Bicer, Ryohei Noma, Bahareh Kiani, Olga Efa, Martin Büscher, Tetsuichi Wazawa, Masahiro Sonoshita, Hirofumi Shintaku, Takeharu Nagai, Sigurd Braun, Jessica P. Houston, Sherif Rashad, Kuniyasu Niizuma, Keisuke Goda

“…Moreover, our FLIM system distinguishes subpopulations in male rat glioma and captures dynamic changes in the cell nucleus induced by an anti-cancer drug. FLIM flow cytometry significantly enhances cellular analysis capabilities, providing detailed insights into cellular functions, interactions, and environments.…”
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Acupuncture for patients with type 2 diabetes mellitus with dry eye: protocol for a systematic review and meta-analysis by Ting Li, Xin Xu, Juan Wei, Qingbo Wei, Zhouyu Xie, Xiangyu Bian, Yunchuan Wu

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Identification of Survival Risk and Immune-Related Characteristics of Kidney Renal Clear Cell Carcinoma by Xiaobin Wu, Yonghui Liang, Xian Chen, Xiangyang Long, Wujun Xu, Li Liu, Binhui Wang, Xiong Zou

“…A series of information such as RNA sequence, clinical data, and tumor mutation burden (TMB) of KIRC patients were downloaded through The Cancer Genome Atlas (TCGA). Next, combining the survival information and gene expression data of TCGA and Gene Expression Omnibus (GEO), we established an immune gene-related prognosis model (IGRPM) and analyzed it. …”
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Association between retinal markers and cognition in older adults: a systematic review by Gerald Liew, Bamini Gopinath, Joyce Chan, Joyce Siette, Varshanie Jeevakumar, Rebekah Sefton, Tejal M Shah

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