Human development II: We Need an Integrated Theory for Matter, Life and Consciousness to Understand Life and Healing by Sören Ventegodt, Tyge Dahl Hermansen, Maj Lyck Nielsen, Birgitte Clausen, Joav Merrick

“…Recently, we have observed a new pattern of extremely rapid, spontaneous healing that apparently can facilitate even the spontaneous remission of cancer and the spontaneous recovery of mental diseases like schizophrenia and borderline schizophrenia. …”
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Reduced UPF1 levels in senescence impair nonsense-mediated mRNA decay by Dahyeon Koh, Yebin Lee, Kyuchan Kim, Hyeong Bin Jeon, Chaehwan Oh, Sangik Hwang, Minjung Lim, Kwang-Pyo Lee, Yeonkyoung Park, Yong Ryoul Yang, Yoon Ki Kim, Donghwan Shim, Myriam Gorospe, Ji Heon Noh, Kyoung Mi Kim

“…While the role of NMD in cancer and developmental and genetic diseases is well documented, its implications in human aging remain largely unexplored. …”
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Intraoperative Fluorescence Imaging During Robotic Pancreatoduodenectomy to Detect Suture-Induced Hypoperfusion of the Pancreatic Stump as a Predictor of Postoperative Pancreatic F... by Jeffrey W. Chen, Sanne Lof, Maurice J. W. Zwart, Olivier R. Busch, Freek Daams, Sebastiaan Festen, Zhi Ven Fong, Melissa E. Hogg, Maxime D. Slooter, Els J.M. Nieveen van Dijkum, Marc G. Besselink, for HPB-Amsterdam

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Three effective cases of transcatheter arterial embolization after atezolizumab and bevacizumab treatment for hepatocellular carcinoma: a case report by Koji Rinka, Kiyohide Kioka, Yuga Amano, Takashi Nakai, Yasuko Kawasaki, Norifumi Kawada

“…Abstract Background The Barcelona Clinic Liver Cancer staging system classifies hepatocellular carcinoma on the basis of tumor characteristics, liver function, and Eastern Cooperative Oncology Group performance status. …”
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Identification and analysis of pancreatic intraepithelial neoplasia: opportunities and challenges by Ling-ling Pian, Ling-ling Pian, Mei-hui Song, Teng-fei Wang, Teng-fei Wang, Ling Qi, Tie-li Peng, Ke-ping Xie

“…In addition, metabolomics technologies and miRNAs are playing an increasingly important role in the field of cancer diagnosis, offering more possibilities for efficient identification of PanIN. …”
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Broad-spectrum bioactivities of a sulfated heteropolysaccharide from Bacillus tequilensis MYG163: antioxidant, anti-Inflammatory, anticancer, antimicrobial, and antibiofilm propert... by Maha Abdullah Alwaili, Mohammed A. Alshehri, Thanaa R. Abdulrahman, Faisal Miqad K. Albaqami, Abdullah Alghamdi, Mona Othman I. Albureikan, Taghreed Shamrani, Abdullah Albelasi, Mohammad El-Nablaway, Samy Selim, Ahmed Ghareeb

“…While safe for normal cells, it demonstrated cytotoxicity against colon (IC50 = 203.25 µg/mL) and pancreatic cancer cells (IC50 = 122.99 µg/mL). The compound effectively inhibited Candida albicans (MIC = 15.62 µg/mL) and showed superior antibacterial activity compared to gentamicin against Enterococcus faecalis (33 mm vs. 30 mm) and Klebsiella pneumoniae (42 mm vs. 17 mm). …”
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Assessment of antenatal care quality in Ethiopia: Facility-based study using service provision assessment data. by Addisu Alehegn Alemu, Alec Welsh, Theodros Getachew, Marjan Khajehei

“…Blood pressure measurement was the most commonly performed ANC component, at 79.5%, and breast examination for cancer screening was the most neglected component of ANC, at 3.3%. …”
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Alternative splicing in the DBD linker region of p63 modulates binding to DNA and iASPP in vitro by Rebecca Lotz, Christian Osterburg, Apirat Chaikuad, Sabrina Weber, Masato Akutsu, Anne Christin Machel, Ulrike Beyer, Jakob Gebel, Frank Löhr, Stefan Knapp, Matthias Dobbelstein, Xin Lu, Volker Dötsch

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Classification of Nanomaterial Drug Delivery Systems for Inflammatory Bowel Disease by Wang H, Zhou F, Shen M, Ma R, Yu Q

“…Patients with IBD frequently experience recurrent abdominal pain and bloody diarrhea, while severe cases may result in intestinal obstruction, perforation, and cancer. Lifelong maintenance therapy may thus be needed to manage these symptoms; however, traditional IBD drugs, such as 5-aminosalicylic acid, glucocorticoids, immunosuppressants, and biological agents, are often associated with problems including poor solubility, instability, and ineffective targeting, as well as causing serious side effects in non-target tissues. …”
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Prognostic factors of head and neck cutaneous squamous cell carcinoma: a systematic review by Joshua Lubov, Mathilde Labbé, Krystelle Sioufi, Grégoire B. Morand, Michael P. Hier, Manish Khanna, Khalil Sultanem, Alex M. Mlynarek

“…Abstract Background Head and neck cutaneous squamous cell carcinoma (HNCSCC) is a non-melanoma skin cancer that is mostly caused by solar ultraviolet radiation exposure. …”
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Exploring the prevalence of gout among underrepresented low socioeconomic status type 2 diabetes populations by Jessica Smith, Abey Martin, Jane Mundadan, Michael Roberts, Youssef Roman, Arturo Bravo-Nuevo, Farzaneh Daghigh

“…Exclusion criteria were a personal history of cancer, organ transplantation, or current pregnancy. …”
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Disulfidptosis-related gene SLC3A2: a novel prognostic biomarker in nasopharyngeal carcinoma and head and neck squamous cell carcinoma by Xinyi Zhang, Yiqi Lin, Liang Shi, Aixia Zhai, Chao Wu, Qian-Ying Zhu

“…Several studies in recent years have extensively investigated the function of the disulfidoptosis-related SLC7A11 gene in cancer, but the role of its partner protein, SLC3A2, remains unknown unclear in NPC.MethodsGEO database analysis confirmed SLC3A2's prognostic impact on nasopharyngeal carcinoma. …”
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Metabolites Profiling of Soil Actinomycetes with Antimicrobial and Anticancer Activities by Ram Prabodh Yadav, Bibek Raj Bhattarai, Rabin Budhathoki, Padamlal Budthapa, Monika Rana, Rubin Thapa Magar, Bijaya Bahadur Thapa, Akkal Dev Mishra, Niranjan Parajuli

“…This study enhances our comprehension of the bioactive potential of these microorganisms and underscores their value as a source for creating novel therapeutics to address multi-resistant infections and cancer demands. These findings show that actinomycetes from Nepalese soil have high prospects for biological applications. …”
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Argonaute2 modulates megakaryocyte development and sex-specific control of platelet protein expression and reactivity by Sophia Lazar, Jeremy G.T. Wurtzel, Shayan Askari, Matthew Cooper, Xuefei Zhao, Peisong Ma, Lawrence E. Goldfinger

“…Female Ago2-deleted platelets selectively showed downregulation of a protein cohort established in breast cancer cells to be transcriptionally regulated by estrogen receptor-beta coupled to Ago2, whereas male Ago2-deleted platelets did not. …”
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Nanoparticle accumulation and penetration in 3D tumor models: the effect of size, shape, and surface charge by Pierre Cybulski, Maria Bravo, Maria Bravo, Jim Jui-Kai Chen, Indra Van Zundert, Sandra Krzyzowska, Farsai Taemaitree, Hiroshi Uji-i, Hiroshi Uji-i, Hiroshi Uji-i, Johan Hofkens, Johan Hofkens, Susana Rocha, Beatrice Fortuni

“…Preclinical studies have demonstrated that nanoparticles (NPs) hold significant potential for advancing cancer therapy by enhancing therapeutic efficacy while reducing side effects. …”
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BTEX Exposure Assessment and Inhalation Health Risks to Traffic Policemen in the Klang Valley Region, Malaysia by Noor Fatihah Mohamad Fandi, Juliana Jalaludin, Mohd Talib Latif, Haris Hafizal Abd Hamid, Mohd Fairus Awang

“…A probabilistic method based on Monte Carlo simulation was applied to determine the cancer risk (CR) and hazard quotient (HQ), and a sensitivity analysis was performed to identify the greatest contributors to the estimated risks. …”
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Characterizing Industrial VOC Hotspots in One of Eastern China’s Largest Petrochemical Parks Using Mobile PTR–ToF–MS Measurements by Jie Fang, Zihang Zhang, Zeye Liang, Ming Wang, Yunjiang Zhang, Xinlei Ge

“…The overall OH reactivity, aerosol formation potential, and lifetime cancer risk of the industrial zone were also substantially higher than those in the background zone. …”
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Exosomal miR-21-5p from glioma associated mesenchymal stem cells promotes the progression and glycolysis of glioblastoma via PDHA1 by Yanbin Zhang, Peng Lv, Qing Zhang, Wei Xiang, Xiaobing Jiang, Zijun Guo, Tao Zhang

“…Pyruvate dehydrogenase A1 (PDHA1) is a key component in both the tricarboxylic acid cycle and glycolysis, playing an important role in the metabolic processes related to cancer, but its role in GBM remains unclear. Glioma associated mesenchymal stem cells (GaMSC) play a significant role in the development of glioma. …”
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Adding Bismuth to Rabeprazole-Based First-Line Triple Therapy Does Not Improve the Eradication of Helicobacter pylori by Meng-Chieh Wu, Yao-Kuang Wang, Chung-Jung Liu, Fang-Jung Yu, Fu-Chen Kuo, Min-Li Liu, Chao-Hung Kuo, Deng-Chyang Wu, Yao-Kang Huang, I-Chen Wu

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A remarkable and durable response to tislelizumab treatment of an anaplastic thyroid carcinoma without targetable genomic alterations: a case report by Jingjing Chai, Jiaqi Lv, Jian Xiong, Xiuwen Chen, Senyuan Luo, Zhiguo Luo, Zhiguo Luo, Ming Luo

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