A thorny pathway of macrophage activating factor (GcMAF): from bench to bedside by A. A. Ostanin, S. S. Kirikovich, E. V. Dolgova, А. S. Proskurina, E. R. Chernykh, S. S. Bogachev

“…The role of DBP in the resistance of organism against a number of diseases is supported by the increased risk of a variety of severe illnesses (amyotrophic lateral sclerosis, colorectal cancer etc.) in patients deficient for GcMAF due to homozygosity for defective DBP alleles. …”
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Genetic mechanisms of the influence of light and phototransduction on Drosophila melanogaster lifespan by I. A. Solovev, M. V. Shaposhnikov, A. A. Moskalev

“…Numerous literature sources establish a connection between the duration of exposure to daylight, carcinogenesis and longevity, convincingly showing a significant reduction in the incidence of cancer in blind people, as well as in animal models. …”
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Delayed-release prednisone improves fatigue and health-related quality of life: findings from the CAPRA-2 double-blind randomised study in rheumatoid arthritis by Frank Buttgereit, Rieke Alten, Amy Grahn, Robert J Holt, Patricia Rice

“…General quality of life was assessed using the general score and individual domains of Functional Assessment of Cancer Therapy-General (FACT-G) and SF-36.Results The change from baseline to week 12 in FACIT-F score was statistically significantly different with DR prednisone/DMARD (3.8) versus placebo/DMARD (1.6; difference 2.2, p=0.0032). …”
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Prevalencia de tabaquismo en pacientes con enfermedad pulmonar obstructiva crónica. Cienfuegos, 2017- 2018 by Ahmed Pomares Ávalos, Marian Amanda Vázquez Núñez, Erika Solange Ruíz Domínguez, Amanda Chaviano Rodríguez

“…Las variables de estudio fueron: edad, sexo, escolaridad, ocupación, procedencia, tabaquismo, cantidad de cigarros fumados diariamente, cantidad de años fumando, enfermedad pulmonar obstructiva crónica, hipertensión arterial, diabetes mellitus, insuficiencia renal crónica, cardiopatías isquémica, accidente vascular encefálico y cáncer. Se utilizó como instrumento de recogida de información el cuestionario utilizado por el proyecto CARMEN (Conjunto de Acciones para Reducir las Enfermedades no Transmisibles). …”
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Thapsigargin Induces Apoptosis by Impairing Cytoskeleton Dynamics in Human Lung Adenocarcinoma Cells by Fei Wang, Da-zhong Liu, Hao Xu, Yi Li, Wei Wang, Bai-lu Liu, Lin-you Zhang

“…The present findings highlight important roles of calcium entry in cytoskeleton organization and apoptosis in human lung adenocarcinoma cells and will help to set a stage to the clinical treatment of cancer cell metastasis.…”
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Investigating the effects of home-based rehabilitation after intensive inpatient rehabilitation on motor function, activities of daily living, and caregiver burden. by Kenji Sato, Eri Otaka, Kenichi Ozaki, Kenta Shiramoto, Rie Narukawa, Takeshi Kamiya, Masaki Kamiya, Daiki Shimotori, Chiaki Kamizato, Naoki Itoh, Hitoshi Kagaya, Izumi Kondo

“…<h4>Results</h4>The participants included in this study had orthopedic (n = 76), cerebrovascular (n = 50), neuromuscular (n = 11), cardiovascular (n = 5), respiratory (n = 3), cancer (n = 3) and other diseases (n = 2). The mean (SD) time from discharge to the start of rehabilitation was 4 (4) days. …”
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Ultrasound-assisted enhancement of bioactive compounds in hawthorn vinegar: A functional approach to anticancer and antidiabetic effects by Selim Öğüt, Melikenur Türkol, Seydi Yıkmış, Esra Bozgeyik, Gholamreza Abdi, Emine Kocyigit, Rana Muhammad Aadil, Nilay Seyidoglu, Deniz Karakçı, Nazlı Tokatlı

“…In experiments on A549 (lung), MCF-7 (breast) and HT-29 (colon) cancer cell lines, ultrasound-treated vinegar increased apoptotic effects, suppressed cell migration and reduced necrosis rates in some cell lines. …”
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HPV16E6-Dependent c-Fos Expression Contributes to AP-1 Complex Formation in SiHa Cells by Feixin Liang, Shinichiro Kina, Hiroyuki Takemoto, Akira Matayoshi, Thongsavanh Phonaphonh, Nao Sunagawa, Keiichi Arakaki, Akira Arasaki, Hai Kuang, Hajime Sunakawa

“…To date, the major role of HPV16E6 in cancer has been considered to be its ability to inhibit the p53 tumor-suppressor protein, thereby thwarting p53-mediated cytotoxic responses to cellular stress signals. …”
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Identification of a Novel Anticancer Oligopeptide from Perilla frutescens (L.) Britt. and Its Enhanced Anticancer Effect by Targeted Nanoparticles In Vitro by Dong-Liang He, Ri-Ya Jin, Hui-Zhen Li, Qing-Ye Liu, Zhi-Jun Zhang

“…Then, the particle size, zeta potential, encapsulation efficiency (EE), drug loading efficiency (LE), the cumulative release rates of NPs, and its cytotoxic effect on cancer cells were investigated. Results. Three fractions were isolated by the chromatography assay. …”
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Studies of the Antiproliferative Activity of Ruthenium (II) Cyclopentadienyl-Derived Complexes with Nitrogen Coordinated Ligands by Virtudes Moreno, Julia Lorenzo, Francesc X. Aviles, M. Helena Garcia, João P. Ribeiro, Tânia S. Morais, Pedro Florindo, M. Paula Robalo

“…Compounds 1, 2, and 3 showed much higher cytotoxicity than the cisplatin against human leukaemia cancer cells (HL-60 cells).…”
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Pharmacokinetics and Bioavailability Study of Tubeimoside I in ICR Mice by UPLC-MS/MS by Lianguo Chen, Qinghua Weng, Feifei Li, Jinlai Liu, Xueliang Zhang, Yunfang Zhou

“…The aim of this study is to establish and validate a rapid, selective, and sensitive ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method to determine tubeimoside I (TBMS-I) in ICR (Institute of Cancer Research) mouse whole blood and its application in the pharmacokinetics and bioavailability study. …”
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Construction of cuproptosis-related genes risk model predicts the prognosis of Uterine Corpus Endometrial Carcinoma by Yanfang Huang, Guoxian Luo, Xiujie Sheng, Jianqi Li

“…This study aims to identify prognostically relevant cuproptosis-related genes in endometrial cancer. Cuproptosis-related genes were sourced from previously published studies and the FerrDb database. …”
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Deciphering of differences in gut microbiota and plasma metabolites profile between non-obese and obese Golden Retrievers dogs by Yazhen Cai, Huayu Tang, Guilin Xiang, Hongyu Yi, Jie Zhong, Zhaoxi Xie, Qinfeng Hu, Romaissaa El Bouhi, Pan Zhou, Yong Zhang, Honglin Yan

“…IntroductionGolden Retrievers have a high risk of obesity, which is prevalent in dogs and is associated with inflammation and cancer, impairing the health and life expectancy of companion animals. …”
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Acute kidney injury in patients with COVID-19 in the intensive care unit: evaluation of risk factors and mortality in a national cohort by Pål Klepstad, Eirik Aasen Aukland, Stein Magnus Aukland, Fatemeh Zamanzad Ghavidel, Eirik Alnes Buanes

“…Survival for the study population at 30 and 90 days was 82.5% and 77.6%, respectively. Cancer was a predictor of 30-day mortality. Age, acute circulatory failure at hospital admission and AKI at ICU admission were predictors of both 30-day and 90-day mortality.Conclusions A high number of patients with COVID-19 had AKI at ICU admission. …”
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Impact of bone quality on surgical decision-making in total hip arthroplasty: a qualitative analysis in the UK by Stella Mavroveli, Justin Cobb, Sanjeeve Sabharwal, Monil Karia, Alex Abouharb

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Measurement the Physiological Properties of Water Pipe Smokers in Shekhan Distract by Abdullah. M. Al-Saiegh, Turki Sabri Haji, Jihan Saado Ahmed, Alaa Azzo Aslo, Firas Faris Khalaf

“…Smoking is one of the old habits used by humans before 400 years ago, where this custom was exclusively used in males with the development of time, tools, ingredients and flavors that used in hookah the women also started smoking, which led to an increase in the prevalence of use in many countries of the world Smoking is one of the reasons that lead to an increase in the percentage incidence of lung cancer, chronic lung disease ,mouth disease ,teeth deformation and gingivitis. …”
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Substrains of Inbred Mice Differ in Their Physical Activity as a Behavior by Dario Coletti, Emanuele Berardi, Paola Aulino, Eleonora Rossi, Viviana Moresi, Zhenlin Li, Sergio Adamo

“…Spontaneous activity persists in pathological conditions, such as cancer-associated cachexia. This important amount of physical activity results in a minor muscle adaptation to endurance exercise over a three-week period; indeed, only a nonsignificant increase in NADH transferase+ fibers occurs in this time frame.…”
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Exercise barriers and facilitators during hematopoietic stem cell transplantation: a qualitative study by Kerry Courneya, Mi-Seong Yu, Ki-Yong An, Jiyong Byeon, Meeok CHOI, June-Won Cheong, Justin Y Jeon

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Caracterización clínico-epidemiológica de la enfermedad de Paget de la mama. Estudio de 37 años by Lidia Torres Ajá, José Alberto Puerto Lorenzo, Emilio Guerra Pérez, Neylin Caballero Aja

“…<p><strong>Fundamento</strong>: La enfermedad de Paget de la mama es poco frecuente, ya que representa solo del 1 al 1,5 % del total de los cánceres mamarios que se reportan. Algunos autores la consideran una forma especial de cáncer de mama y otros solo una extensión de un carcinoma intraductal que alcanza el pezón.…”
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Non-alcoholic fatty liver disease: comparative assessment of diagnostic and treatment approaches in the Russian Federation and People’s Republic of China by M. Ch. Semenistaya, Fan Jian-Gao, O. B. Velichenko, Ye. A. Kuznetsova, Ch. S. Pavlov

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