Morphological Evidence for a Subpopulation Selection Effect by Estrogen and Antiestrogen Treatments in the Heterogeneous MCF-7 Cell Line by Jacqueline Palmari, France Wallet, Julien Berard, Yolande Berthois, Pierre Marie Martin, Christophe Dussert

“…The method, previously used to analyse the proliferation of the breast cancer cell line MCF‐7, was applied here to analyse the growth of this cell line under estradiol (E2), hydroxytamoxifen (OH‐TAM), and both E2 and OH‐TAM treatments. …”
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Serum assisted PD-L1 aptamer screening for improving its stability by Yu Zhou, Haozhe Zhang, Yujing Ding, Changyuan Yu, Hao Li

“…With its improved stability, higher affinity and specificity, Apt-S1 holds great potential for applications in PD-L1 assisted cancer diagnosis and treatment. Meanwhile, the results obtained in this work provide further evidence of the advantages of the real capture-SELEX strategy in improving aptamer stability compared to the traditional strategy.…”
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The Prognostic Significance of TRs in Hepatocellular Carcinoma: Insights from TCGA and GEO Databases by Hao Zhou, Weijie Wang, Ruopeng Liang, Rongtao Zhu, Jiahui Cao, Chenguang Sun, Yuling Sun

“…Methods: This study utilized Kaplan-Meier analysis of TR expression profiles from The Cancer Genome Atlas (TCGA). Expression levels of TRs in HCC and immune single cells were assessed using datasets from the Gene Expression Omnibus (GEO) and TCGA, analyzed with R software. …”
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Stent Selection for Endoscopic Ultrasound-Guided Drainage of Pancreatic Fluid Collections: A Multicenter Study in China by Hui Lin, Xian-Bao Zhan, Si-Yu Sun, Xiu-Jiang Yang, Zhen-Dong Jin, Duo-Wu Zou, Zhao-Shen Li

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Development of a 3-MicroRNA Signature and Nomogram for Predicting the Survival of Patients with Uveal Melanoma Based on TCGA and GEO Databases by Jun Zuo, Hongquan Ye, Jing Tang, Jianqun Lu, Qi Wan

“…Methods. miRNA and mRNA sequencing data for 80 UM patients were obtained from The Cancer Genome Atlas (TCGA) database. The patients were further randomly assigned to a training set (n = 40, used to identify key miRNAs) and a testing set (n = 40, used to internally verify the signature). …”
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Disease prediction by network information gain on a single sample basis by Jinling Yan, Peiluan Li, Ying Li, Rong Gao, Cheng Bi, Luonan Chen

“…., an influenza dataset and three cancer datasets.…”
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A comprehensive analysis to reveal the underlying molecular mechanisms of natural killer cell in thyroid carcinoma based on single-cell RNA sequencing data by Xiaoqiong Li, Kejiang Wang, Jiaxin Liu, Yan Li

“…Abstract Background Thyroid carcinoma (THCA) is the most common cancer of the endocrine system. Natural killer (NK) cell play an important role in tumor immune surveillance. …”
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Biomedical named entity recognition using improved green anaconda-assisted Bi-GRU-based hierarchical ResNet model by Ram Chandra Bhushan, Rakesh Kumar Donthi, Yojitha Chilukuri, Ulligaddala Srinivasarao, Polisetty Swetha

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Endometrial polyps with bizarre stromal cells: a Benign or a low-grade lesion? by Musen Wang, Fei Gao, Hongkai Zhang, Wenxin Zheng

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2’-Fucosyllactose alleviate immune checkpoint blockade-associated colitis by reshaping gut microbiota and activating AHR pathway by Shikai Yan, Leilei Yu, Fengwei Tian, Jianxin Zhao, Wei Chen, Qixiao Zhai

“…Immune checkpoint blockade (ICB) therapeutics are highly effective in cancer immunotherapy, but gastrointestinal toxicity limited the application. …”
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A Novel Attention-Guided Enhanced U-Net With Hybrid Edge-Preserving Structural Loss for Low-Dose CT Image Denoising by Muhammad Zubair, Helmi Md Rais, Talal Alazemi

“…Computed Tomography (CT) scan, pivotal for medical diagnostics, involves exposure to electromagnetic radiation, potentially elevating the risk of leukemia and cancer. Low-dose CT (LDCT) imaging has emerged to mitigate these risks, extensively reducing radiation exposure by up to 86%. …”
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Design and In Vitro Biological Evaluation of a Novel Organotin(IV) Complex with 1-(4-Carboxyphenyl)-3-ethyl-3-methylpyrrolidine-2,5-dione by Nebojša Đ. Pantelić, Bojana B. Zmejkovski, Željko Žižak, Nebojša R. Banjac, Bojan Đ. Božić, Tatjana P. Stanojković, Goran N. Kaluđerović

“…In vitro anticancer activity of ligand precursor and synthesized organotin(IV) compound was determined against tumor cell lines: human adenocarcinoma (HeLa), human myelogenous leukemia (K562), and human breast cancer (MDA-MB-453), using microculture tetrazolium test (MTT) assay. …”
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Homologous In-Radiolabeled Platelet Survival and Sequestration Exploration for Refractory Immunologic Thrombocytopenic purpura in Children: A Strategy to Avoid Unnecessary Splenect... by Julien Dubois PharmD, Florentin Kucharczak PhD, Léa De Neef PharmD, Virginie Kouyoumdjian PharmD, Gilles Palenzuela MD, Virginie Tunez MD, Denis Mariano-Goulart MD, PhD, Aurélie Bourdon MD, Tom Paunet MD

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Extreme Environment Streptomyces: Potential Sources for New Antibacterial and Anticancer Drug Leads? by Periyasamy Sivalingam, Kui Hong, John Pote, Kandasamy Prabakar

“…Consequently, the increased morbidity and mortality, which are associated with multidrug resistance bacteria, urgently require the discovery of novel and more efficient drugs. Conversely, cancer is a growing complex human disease that demands new drugs with no or fewer side effects. …”
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Association between contextual factors and vaccine coverage against human papilomavirus in adolescents in the state of Minas Gerais, Brazil: global spatial regressions by Bianca Maria Oliveira Luvisaro, Thales Philipe Rodrigues da Silva, Josianne Dias Gusmão, Marcela Lencine Ferraz, Luciana Maiara Diogo Nascimento, Larissa Pereira Gomes, Fernanda Penido Matozinhos

“…The disparities in vaccination coverage rates observed across the state highlight the need for targeted interventions to increase coverage and reduce health issues, such as cervical cancer.…”
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The Studies of Chlorogenic Acid Antitumor Mechanism by Gene Chip Detection: The Immune Pathway Gene Expression by Tian Yi Kang, Hua Rong Yang, Jie Zhang, Dan Li, Jie Lin, Li Wang, XiaoPing Xu

“…Persistently increasing incident of cancer in human beings has served to emphasize the importance of studies on mechanism of antitumor substances. …”
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RNA-BioLens: A Novel Raspberry Pi-Based Digital Microscope With Image Processing for Acute Lymphoblastic Leukemia Detection by Angeline Dwi Sanjaya, Rachmad Setiawan, Nada Fitrieyatul Hikmah

“…Accurate blood cell analysis is essential for precise diagnosis, especially in identifying cancerous cells, such as Acute Lymphoblastic Leukemia (ALL) — Indonesia’s most common childhood cancer, according to the Indonesian Pediatric Society (IDAI). …”
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Metastatic Malignant Ectomesenchymoma Initially Presenting as a Pelvic Mass: Report of a Case and Review of Literature by A. Nael, P. Siaghani, W. W. Wu, K. Nael, Lisa Shane, S. G. Romansky

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Deep learning-based skin lesion analysis using hybrid ResUNet++ and modified AlexNet-Random Forest for enhanced segmentation and classification. by Saleem Mustafa, Arfan Jaffar, Muhammad Rashid, Sheeraz Akram, Sohail Masood Bhatti

“…Skin cancer is considered globally as the most fatal disease. …”
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Exploring the mechanism of Schisandra rubriflora in the treatment of polycystic ovary syndrome based on network pharmacology and molecular docking by Zhengyan Dou, Qingxian Li, Jing Zhang, Xin Zhang

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