A Cost-effectiveness Analysis of Brentuximab Vedotin in Relapsed or Refractory Systemic Anaplastic Large Cell Lymphoma by Margaret Hux, Denise Zou, Esprit Ma, Peter Sajosi, Andreas Engstrom, Ross Selby, Eugene Benson, Andrew Briggs, Vijayveer Bonthapally

“…Comparison with conventional chemotherapy was based on data from the Canadian British Columbia Cancer Agency registry from 40 patients starting salvage chemotherapy after front-line treatment between 1980 and 2012. …”
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Scatter Artifact with Ga-68-PSMA-11 PET: Severity Reduced With Furosemide Diuresis and Improved Scatter Correction by Courtney Lawhn-Heath MD, Robert R. Flavell MD, PhD, David E. Korenchan PhD, Timothy Deller MSEE, Spencer Lake MD, Peter R. Carroll MD, MPH, Thomas A. Hope MD

“…Materials and Methods: A total of 139 patients underwent Ga-68-PSMA-11 PET imaging for prostate cancer: 47 non-time-of-flight (non-TOF) PET/computed tomography, 51 PET/magnetic resonance imaging (MRI) using the standard TOF scatter correction algorithm, and 41 PET/MRI using an improved TOF scatter correction algorithm. …”
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Prognostic value of albumin-bilirubin grade in patients with cholangiocarcinoma: a systematic review and meta-analysis by Mahyaar Omouri-Kharashtomi, Seyedeh Yasaman Alemohammad, Negin Moazed, Inas Afzali Nezhad, Hamed Ghoshouni

“…Abstract Background Cholangiocarcinoma (CCA) is a type of cancer that develops in the biliary tract. CCA accounts for 10% of primary hepatic cancers and is characterized by its aggressive nature and poor prognosis. …”
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Design of a dual randomized trial in a type 2 hybrid effectiveness—implementation study by June Stevens, Sarah Denton Mills, Mary-Louise Millett, Feng-Chang Lin, Jennifer Leeman

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Extraskeletal Myxoid Chondrosarcoma with Small Bowel Metastasis Causing Bowel Obstruction by Ernesto Bustinza-Linares, Francisco Socola, Vinicius Ernani, Shelly A. Miller, Jonathan C. Trent

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Computational assessment of measurable residual disease in acute myeloid leukemia using mixture models by Tim R. Mocking, Angèle Kelder, Tom Reuvekamp, Lok Lam Ngai, Philip Rutten, Patrycja Gradowska, Arjan A. van de Loosdrecht, Jacqueline Cloos, Costa Bachas

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Interaction between diet composition and gut microbiota and its impact on gastrointestinal tract health by Muhammad Shahid Riaz Rajoka, Junling Shi, Hafiza Mahreen Mehwish, Jing Zhu, Qi Li, Dongyan Shao, Qingsheng Huang, Hui Yang

“…Diet composition plays an important role in the control of gut microbial populations and, thus, in the prevention, management and treatment of certain diseases such as cancer, diabetes. A comprehensive analysis of previously reported results revealed that the gut microbiota can be modulated by diet and the composition of gut microbiota can be influenced by various diet components. …”
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Granzyme B PET Imaging Stratifies Immune Checkpoint Inhibitor Response in Hepatocellular Carcinoma by Julian L. Goggi, Boominathan Ramasamy, Yun Xuan Tan, Siddesh V. Hartimath, Jun Rong Tang, Peter Cheng, Rasha Msallam, Ann-Marie Chacko, You Yi Hwang, Edward G. Robins

“…Hepatocellular carcinoma (HCC) is a notoriously difficult cancer to treat. The recent development of immune checkpoint inhibitors has revolutionised HCC therapy; however, successful response is only observed in a small percentage of patients. …”
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The care needs of persons with oropharyngeal dysphagia and their informal caregivers: A scoping review. by Aurora Ninfa, Valeria Crispiatico, Nicole Pizzorni, Marta Bassi, Giovanni Casazza, Antonio Schindler, Antonella Delle Fave

“…Research methods primarily consisted of qualitative interviews and focus groups (14 studies, 93.3%); head and neck cancer was the most frequent cause of patients' dysphagia (8 studies, 53.3%); caregivers' perspective was seldom investigated (5 studies, 33.3%). …”
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Establishment of a Model of Microencapsulated SGC7901 Human Gastric Carcinoma Cells Cocultured with Tumor-Associated Macrophages by Jin-Ming Zhu, Xiu-Lian Quan, Shi-Chao Han, Xue-Jun Fan, He-Ming Li, Shan-Shan Liang, Xi Chen, Ruo-Yu Wang, Xue-Ning Ji

“…The important factors of poor survival of gastric cancer (GC) are relapse and metastasis. For further elucidation of the mechanism, a culture system mimicking the microenvironment of the tumor in humans was needed. …”
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Carotid endarterectomy in the setting of persistent hypoglossal artery by Samuel D. Leonard, MD, Lili Sadri, MD, Hung Nguyen, MD, Naveed Saqib, MD, Marvin Heck, MD, Gordon Martin, MD

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Views and opinions of the general public about the reimbursement of expensive medicines in the Netherlands. by Féline E V Scheijmans, Roosmarijn van der Wal, Margot L Zomers, Johannes J M van Delden, W Ludo van der Pol, Ghislaine J M W van Thiel

“…<h4>Objectives</h4>Solidarity-based healthcare systems are being challenged by the incremental costs of new and expensive medicines for cancer and rare diseases. To regulate reimbursement of such drugs, the Dutch government introduced a policy instrument known as the Coverage Lock (CL) in 2015. …”
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Comparative Antiviral Efficacy of Generic Sofosbuvir versus Brand Name Sofosbuvir with Ribavirin for the Treatment of Hepatitis C by L. Tang, M. Kamat, A. Shukla, M. Vora, C. Kalal, S. Kottilil, S. Shah

“…Chronic hepatitis C infection is a major cause for liver failure and liver cancer and can be treated with highly effective all oral directly acting antiviral (DAA) drugs. …”
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A Journey into the Complexity of Temporo-Insular Gliomas: Case Report and Literature Review by Manuel De Jesus Encarnacion Ramirez, Gervith Reyes Soto, Carlos Castillo Rangel

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Tobacco Stained Fingers and Its Association with Death and Hospital Admission: A Retrospective Cohort Study. by Gregor John, Céline Louis, Amandine Berner, Daniel Genné

“…Multivariable Cox models were used to adjust for confounding factors: age, gender, pack-year unit smoked, cancer, harmful alcohol use and diabetes. The number of hospital admissions was compared through a negative binomial regression and adjusted for the follow-up time, diabetes, and alcohol use.…”
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UHPLC-UV method validation for simultaneous quantification of vitexin and isovitexin from Santalum album L. leaves by Thi Kim Phung Phan, Minh Quan Le, Kien Duc Ngo

“…Studies have revealed that the leaves contain two main active ingredients vitexin and isovitexin, which have demonstrated significant potential in treating diabetes, cancer, and inflammation. To contribute to the standardization of the title medicinal herb and its formula, a simple, fast precise and selective method for the simultaneous quantification of vitexin and isovitexin using ultra-performance liquid chromatography (UHPLC) has been developed and validated. …”
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Identification of an Inflammatory Response-Related Gene Signature to Predict Survival and Immune Status in Glioma Patients by Zhaoyue Yan, Yushuai Gao, Jinliang Yu, Zhiyuan Shen, Xingyao Bu

“…Glioma is the most common primary brain tumor with high mortality and poor outcomes. As a hallmark of cancers, inflammatory responses are crucial for their progression. …”
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Elastography Evaluation of Benign Thyroid Nodules in Patients Affected by Hashimoto’s Thyroiditis by Carlo Cappelli, Ilenia Pirola, Elena Gandossi, Annamaria Formenti, Barbara Agosti, Maurizio Castellano

“…Elastography appears to have limited value in detecting thyroid cancer in patients affected by Hashimoto’s thyroiditis with severe hypoechoic thyroid tissue.…”
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Anticancer effects of 7,8-dihydromethysticin in human leukemia cells are mediated via cell-cycle dysregulation, inhibition of cell migration and invasion and targeting JAK/STAT pat... by Xiao Yi, Deng Taoran, Jiang Lijun, Wang Di

“…The main focus of this research work was to study the anti-cancer properties of 7,8-dihydromethysticin against HL-60 leukemia cells. …”
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Altered Protein Structures and Neoepitopes in Lupus Neutrophils From Dysregulated Splicing of Messenger RNA by Rayan Najjar, Xiaoxing Wang, Jose Mario Bello Pineda, Hugh Alessi, Alison Bays, Robert K. Bradley, James N. Jarvis, Tomas Mustelin

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