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14481
GC-MS Analysis of Bioactive Compounds in Methanolic Extracts of Papaver decaisnei and Determination of Its Antioxidants and Anticancer Activities
Published 2022-01-01“…The current study investigates the methanol (99.9%) extracts (10 μg/mL) of roots, leaves, and flowers of Papaver decaisnei in terms of phytochemistry by gas chromatography-mass spectrophotometry GC-MS, in vitro antioxidant activity by radical scavenging and reducing power assays, and finally, the anticancer actions as IC50 (inhibitory concentration at 50%) against human colorectal adenocarcinoma (Caco-2), mammary cancer cells (MCF-7), and human cervical carcinoma (HeLa) cells. …”
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14482
Subcritical water extraction of dandelion (Taraxacum officinale L.) flowers: Influence of temperature on polyphenols content and antioxidant activity
Published 2024-01-01“…Described as non-toxic, the herb has been consumed in various forms as a valuable source of nutrients, minerals and vitamins, the consumption of which may help prevent or reduce the risk of complex diseases such as cancer, obesity, arthritis, hepatitis, cardiovascular and gastrointestinal disorders. …”
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14483
The Role of Beta HPV Types and HPV-Associated Inflammatory Processes in Cutaneous Squamous Cell Carcinoma
Published 2020-01-01“…Cutaneous squamous cell carcinoma (cSCC) is a common form of skin cancer with a complex but not fully understood pathogenesis. …”
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14484
ANALYSIS OF THE INTRAOPERATIVE ULTRASOUND RESULTS IN THE SURGICAL TREATMENT OF RENAL TUMORS
Published 2019-04-01“…Possibilities of IOUS application in the surgical treatment of kidney tumor according to the results of examination and surgical treatment of 145 patients (95 men and 50 women) diagnosed with kidney cancer were evaluated. The patients were divided into 2 groups: group 1 (comparisons) — 76 patients; during the examination and treatment, the IOUS method was not used, group 2 (basic) — 69 patients, who during the surgical treatment used the IOUS method to further clarify the localization, the size and boundaries of the tumor formation.Results. …”
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14485
Beyond Humanoid Prosthetic Hands: Modular Terminal Devices That Improve User Performance
Published 2025-01-01Get full text
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14486
Interventional Protocol for Treatment of Complications after Esophagojejunostomy for Esophagogastric Carcinoma
Published 2019-01-01“…During follow-up, 14 patients died of cancer recurrence, and one died of severe pulmonary infection. …”
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14487
Non-viral systems for intracellular delivery of genome editing tools
Published 2024-04-01“…Conventional vectors are not always suitable for this purpose due to a limited cargo volume, risks related to cancer and immune reactions, toxicity, a need for high-purity viral material and quality control, as well as a possibility of integration of the virus into the host genome leading to overexpression of the vector components and safety problems. …”
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14488
Machine Learning-Based Integrated Analysis of PANoptosis Patterns in Acute Myeloid Leukemia Reveals a Signature Predicting Survival and Immunotherapy
Published 2024-01-01“…Our findings disclosed significant associations between the identified PANRGs, gene clusters, patient survival, immune system, and cancer-related biological processes and pathways. …”
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14489
Bayesian analysis of the rate of spontaneous malignant mesothelioma among BAP1 mutant mice in the absence of asbestos exposure
Published 2025-01-01“…Abstract Cancers of the mesothelium, such as malignant mesothelioma (MM), historically have been attributed solely to exposure to asbestos. …”
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14490
Data-Efficient Bone Segmentation Using Feature Pyramid- Based SegFormer
Published 2024-12-01“…Testing our model on spine images from the Cancer Imaging Archive and our own hand and wrist dataset, ablation studies confirmed that our modifications outperform the original SegFormer, U-Net, and Mask2Former. …”
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14491
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14492
Ticlopidine in Its Prodrug Form Is a Selective Inhibitor of Human NTPDase1
Published 2014-01-01“…Nucleoside triphosphate diphosphohydrolase-1 (NTPDase1), like other ectonucleotidases, controls extracellular nucleotide levels and consequently their (patho)physiological responses such as in thrombosis, inflammation, and cancer. Selective NTPDase1 inhibitors would therefore be very useful. …”
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14493
Pharmaceutical Humanities and Narrative Pharmacy: An Emerging New Concept in Pharmacy
Published 2025-01-01“…Many complex diseases (e.g., cancer, neurological diseases, and mental disorders) remain uncurable for many patients by current pharmacotherapies, and the old beaten paths in our therapeutic thinking may at least partly have to be left behind. …”
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14494
A New Prognostic Indicator of Immune Microenvironment and Therapeutic Response in Lung Adenocarcinoma Based on Peroxisome-Related Genes
Published 2022-01-01“…In LUAD patients, the strong connection between the risk score and overall survival was further verified in three other GEO data sets. TMB and cancer stem cell infiltration were shown to be significantly higher in the high-risk group in comparison to the low-risk group. …”
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14495
Inhibition of Horseradish Peroxidase Activity by Boroxine Derivative, Dipotassium-trioxohydroxytetrafluorotriborate K2[B3O3F4OH]
Published 2017-01-01“…Recently research shows that horseradish peroxidase, HRP, when combined with other compounds, is highly reactive toward different human tumour cells and that better understanding of catalytic mechanism and inhibition HPR could lead to a new targeted cancer therapy. Thus, the inhibition of HRP activity by dipotassium-trioxohydroxytetrafluorotriborate K2[B3O3F4OH] was investigated for possible explanation of previously observed antitumour activities of this promising drug. …”
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14496
Morphology of the Myoepithelial Cell: Immunohistochemical Characterization from Resting to Motile Phase
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14497
Association of Interleukin-18 Gene Polymorphism with Susceptibility to Visceral Leishmaniasis in Endemic Area of Bihar, an Indian Population
Published 2014-01-01“…Genetic polymorphisms in the IL-18 gene have been found to be associated with its expression in cancer, tuberculosis, HBV infection, and various other diseases. …”
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14498
A quantitative spatial cell-cell colocalizations framework enabling comparisons between in vitro assembloids and pathological specimens
Published 2025-02-01“…We perform cell-pair colocalization analysis on multiplexed immunofluorescence images of assembloids constructed with lung adenocarcinoma (LUAD) organoids and cancer-associated fibroblasts derived from human tumors. …”
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14499
Therapeutic Potential of Acanthospermum hispidum: A Comprehensive Analysis of Its Antimicrobial, Antioxidant, and Anticancer Properties
Published 2024-01-01“…Cytotoxicity assay was performed against human breast cancer cell line MCF7 using the MTT assay. Bioactive compounds were identified using GC-MS. …”
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14500
CBL mutations in chronic myelomonocytic leukemia often occur in the RING domain with multiple subclones per patient: Implications for targeting.
Published 2024-01-01“…Chronic myelomonocytic leukemia (CMML) is a rare blood cancer of older adults (3 in every 1,000,000 persons) characterized by poor survival and lacking effective mutation-specific therapy. …”
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