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  1. 14461

    Gastric Polyps and Atrophic Gastritis by I. Yu. Kolesnikova, A. S. Novikova

    Published 2021-06-01
    “…The H. pylori eradication, in contrast to anti-secretory therapy, allows the containment of chronic gastritis and is a critical measure in gastric cancer prevention.…”
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  2. 14462

    From data to diagnosis: leveraging deep learning in IoT-based healthcare by Miracle A. Atianashie, Chukwuma Chinaza Adaobi

    Published 2024-11-01
    “…Furthermore, the implementation of deep learning technologies in healthcare IoT has proven effective in the early detection of critical health conditions, including cancer and neurodegenerative diseases, through sophisticated analysis of medical images and physiological data. …”
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  3. 14463
  4. 14464

    Primary pulmonary meningioma — a rare lung tumor by Galust A. Baksiyan, Alexander A. Zavialov, Sergey V. Lishchuk

    Published 2024-12-01
    “…CLINICAL CASE DESCRIPTION: The patient А. (54 years of age) with a history of combined treatment 9 years ago due to being diagnosed with рТ2аN1М0, stage IIIB cervical cancer. According to the results from the computed tomography of the chest cavity organs, in segments S8/9 of the lower lobe of the right lung, the findings included a subpleural solid mass lesion with the size of 14×11 mm. …”
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  5. 14465
  6. 14466

    Molecular mechanisms of renal cell carcinoma metastasis and potential targets for therapy by Xinwei Li, Xinwei Li, Wei Xiong, Zhiyong Xiong, Zhiyong Xiong, Xiaoping Zhang, Xiaoping Zhang, Xiaoping Zhang

    Published 2025-01-01
    “…Renal cell carcinoma is a common type of cancer, with approximately 30% of patients potentially developing metastatic disease. …”
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  7. 14467

    Antibody-epitope conjugates deliver immunogenic T-cell epitopes more efficiently when close to cell surfaces by W. van der Wulp, W. Luu, M. E. Ressing, J. Schuurman, S. I. van Kasteren, L. Guelen, R. C. Hoeben, B. Bleijlevens, M. H. M. Heemskerk

    Published 2024-12-01
    “…Antibody-mediated delivery of immunogenic viral CD8+ T-cell epitopes to redirect virus-specific T cells toward cancer cells is a promising new therapeutic avenue to increase the immunogenicity of tumors. …”
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  8. 14468

    Cumulative Impact of HIV and Multiple Concurrent Human Papillomavirus Infections on the Risk of Cervical Dysplasia by David H. Adler, Melissa Wallace, Thola Bennie, Beau Abar, Tracy L. Meiring, Anna-Lise Williamson, Linda-Gail Bekker

    Published 2016-01-01
    “…Infection with HIV is known to increase the risk of cervical cancer. In addition, evidence suggests that concurrent infection with multiple human papillomavirus (HPV) genotypes increases the risk of cervical dysplasia more than infection with a single HPV genotype. …”
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  9. 14469
  10. 14470

    Sulfoxidation of pyrimidine thioate derivatives and study their biological activities by Atif A. El-Gharably, A. A. Nassar, N. M. El-Ganzory, Khalil M. Saad-Allah, A. A. El-Barbary

    Published 2025-01-01
    “…Notably, compounds 10 and 12 displayed promising anti-tumor effects, with compound 12 demonstrating superior efficacy against the MCF-7 breast cancer cell line compared to compound 10. The study revealed a spectrum of biological activities across the synthesized derivatives, with modifications often resulting in diminished bioactivity compared to the parent compound 1. …”
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  11. 14471
  12. 14472

    Cytokine Patterns in Brain Tumour Progression by Radu Albulescu, Elena Codrici, Ionela Daniela Popescu, Simona Mihai, Laura Georgiana Necula, Daniel Petrescu, Mihaela Teodoru, Cristiana Pistol Tanase

    Published 2013-01-01
    “…The body’s response to cancer has many parallels with inflammation and repair; the inflammatory cells and cytokines present in tumours are more likely to contribute to tumour growth, progression, and immunosuppression, rather than in building an effective antitumour defence. …”
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  13. 14473

    Manganese-pyrochloric acid photosensitizer nanocomplexes against osteosarcoma: achieving both high activatability and high effectiveness by Xuran Zhang, Xuran Zhang, Jian Wang, Qun Feng, Li Lei, Zhiyong Zhu

    Published 2025-02-01
    “…The nanocomplexes were precisely co-assembled in water to stably co-deliver Mn2+ and PPa, enabling tumor-specific release and fluorescence recovery.ResultsFollowing laser irradiation, the activated PPa significantly enhanced the killing effects on primary cancer cells. Additionally, Mn2+ ions activated the cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) pathway, promoting maturation of dendritic cells (DCs) and augmenting CD8+-mediated antitumor immune responses.DiscussionThis study advances the on-demand activation of photosensitive drugs and photodynamic immunotherapy toward clinical applicability by exploiting Mn2+–PPa nanocomplexes with high activatability and effectiveness for targeted PDT and immunotherapy.…”
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  14. 14474

    Outcomes of Human Papilloma Virus Vaccination in a Private Women Health Clinic in Lebanon by Muhieddine Seoud, Iman Jaafar, Rayan Ghanem, Christiane Soubhieh, Abdallah Adra, Anwar Nassar, Ali Khalil

    Published 2022-01-01
    “…The study aims to report on the feasibility and associated adverse events of HPV-Vaccination (HPVV) in a private clinic setting in Lebanon and, when available, the results of subsequent cervical cancer screening. Methods. Opportunistic HPV vaccination is offered at the Women’s Health Center of the AUBMC. …”
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  15. 14475

    Drug repurposing screen for the rare disease ataxia-telangiectasia by Namrata Jayanth, Gurvan Mahé, Matthew Campbell, Mike Lipkin, Shushant Jain, Rhea van de Bospoort, Jennifer Thornton, Brad Margus, David F. Fischer

    Published 2025-01-01
    “…Ataxia Telangiectasia (A-T) is a rare, autosomal recessive genetic disorder characterized by a variety of symptoms, including progressive neurodegeneration, telangiectasia, immunodeficiency, and an increased susceptibility to cancer. It is caused by bi-allelic mutations impacting a gene encoding a serine/threonine kinase ATM (Ataxia Telangiectasia Mutated), which plays a crucial role in DNA repair and maintenance of genomic stability. …”
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  16. 14476
  17. 14477

    Design, synthesis, and apoptotic antiproliferative action of new benzimidazole/1,2,3-triazole hybrids as EGFR inhibitors by Alshimaa A. Y. Ahmed, Anber F. Mohammed, Zainab M. Almarhoon, Stefan Bräse, Bahaa G. M. Youssif

    Published 2025-01-01
    “…IntroductionThis work outlines the design, synthesis, and biological evaluation of a new series of benzimidazole/1,2,3-triazole hybrids as apoptotic antiproliferative agents that inhibit the EGFR pathway.MethodsThe research assesses the antiproliferative efficacy of compounds 6a-i and 10a-i against various cancer cell lines.Results and DiscussionThe research emphasizing hybrids 6i and 10e for their remarkable activity, with GI50 values of 29 nM and 25 nM, respectively. …”
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  18. 14478

    The anti-melanoma roles and mechanisms of tricholoma isoflavone derivative CA028 by Cheng Liang, Jianfu Jiang, Jinkai Li, Xiao Lin, Wenjun Huang, Keng Po Lai, Jian Chen

    Published 2025-01-01
    “…Abstract As a form of skin cancer, melanoma’s incidence rate is continuing to rise globally. …”
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  19. 14479

    Phytochemical Constituents and Biological Activities of Jasonia glutinosa L.: The First Report for the Plant Growing in North Africa by Hamdoon A. Mohammed, Abdulnaser Kh. Abdulkarim, Abdullah D. Alamami, Fatma A. Elshibani

    Published 2022-01-01
    “…The in vitro antioxidant assays showed 265.55, 513.32, and 27.10 μM Trolox eq/mg of extract in the ABTS, ORAC, and FRAP assays, respectively. Cancer cell growth inhibitions of 9.23, 11.42, and 34.01% at a concentration of 100 μg/mL against MCF-7, HepG2, and PANC-1 cell lines were obtained, which is considered a weak cytotoxic effect when compared to the standard anticancer agent, doxorubicin (DOX). …”
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  20. 14480

    Sub-Tenon Injections of Triamcinolone Acetonide Had Limited Effect on Cystoid Macular Edema Secondary to Nanoparticle Albumin-Bound-Paclitaxel (Abraxane) by Naoki Matsuoka, Hiruma Hasebe, Tetsuji Mayama, Takeo Fukuchi

    Published 2015-01-01
    “…A 39-year-old Japanese woman with breast cancer presents with decreased vision in both eyes while receiving nab-paclitaxel. …”
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