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14301
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14302
Modification of the telomerase gene with human regulatory sequences resets mouse telomeres to human length
Published 2025-02-01“…These mice, with humanized telomere regulation, represent a valuable model to study human aging and cancer.…”
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14303
Imaging cell spheroid clusters: An MRI protocol for non-invasive standardized characterization
Published 2025-01-01“…Despite its limited spatial resolution, this method adeptly reveals information about the composition and vitality of stem cell and cancer spheroids and their micro-environment in a non-invasive manner. …”
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14304
Metal Complexes and Their Role in Treatment of the Arthritis
Published 2024-10-01“…Since then, many useful anti-cancer metal-based drugs have been introduced. However, less attention has been paid to improving inflammatory drugs based on metal complexes. …”
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14305
Lipoprotein Signal Peptide as Adjuvants: Leveraging Lipobox-Driven TLR2 Activation in Modern Vaccine Design
Published 2025-01-01“…The lipidation process is essential for TLR2 recognition and the activation of robust immune responses, positioning lipidated bacterial proteins as potent immunomodulators and adjuvants for vaccines against bacterial-, viral-, and cancer-related antigens. The structural diversity and cleavage pathways of bacterial SPs are critical in determining lipidation efficiency and protein localization, influencing their immunogenic potential. …”
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14306
Ultrabright contrast agents with synergistic Raman enhancements for precise intraoperative imaging and photothermal ablation of orthotopic tumor models
Published 2025-01-01“…Abstract Background Intraoperative imaging is critical for achieving precise cancer resection. Among available techniques, Raman spectral imaging emerges as a promising modality due to its high spatial resolution and signal stability. …”
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14307
Diagnosis dan Penatalaksanaan Karsinoma Sel Skuamosa Glotis Stadium Dini
Published 2016-08-01“…</p><p> </p><p><strong><em>Abstract</em></strong></p><p><em>Laryngeal carsinoma is the common head and neck cancer. More than 90% of laryngeal cancers are squamous cell carcinoma, if the early detected the cure rate can the better. …”
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14308
Cytotoxicity and Genotoxicity of Biogenic Silver Nanoparticles in A549 and BEAS-2B Cell Lines
Published 2022-01-01“…Biogenic silver nanoparticles (AgNPs-GA) were successfully synthesised using Garcinia atroviridis leaf extract as a reducing agent, which has ethnopharmacological claims against various diseases including cancer. Aim of the Study. Aim of the study is to discover whether AgNPs-GA has cytotoxic and genotoxic effects on cancerous (A549) and noncancerous (BEAS-2B) human lung cells. …”
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14309
Structural modeling of NAD+ binding modes to PARP-1
Published 2017-02-01“…Inhibitors of poly (ADP-ribose) polymerase have been shown to be effective in improvement of radiation therapy and chemotherapy of cancer in clinical testing. Development of new poly (ADP-ribose) polymerase-1 inhibitors based on derivatives of natural compounds such as NAD+ represents a novel and promising strategy. …”
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14310
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14311
Primary adenocarcinoma of duodenal bulb mimicking a pancreatic tumor: a case report
Published 2025-12-01“…Duodenal bulb adenocarcinoma is a rare malignancy of the gastrointestinal tract. This cancer often presents with an insidious onset, making it challenging to diagnose early. …”
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14312
p53 dosage can impede KrasG12D- and KrasQ61R-mediated tumorigenesis.
Published 2024-01-01“…Loss of the Trp53 gene encoding the tumor suppressor p53 enhances the ability of oncogenic Kras to initiate tumorigenesis in carcinogen and genetic models of lung cancer. Conversley, an extra copy of Trp53 (Super p53) was recently shown to suppress Kras-induced tumorigenesis in a genetic model of this disease. …”
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14313
Synthesis, Characterization, and In Vitro Drug Delivery Capabilities of (Zn, Al)-Based Layered Double Hydroxide Nanoparticles
Published 2015-01-01“…There is an urgent need for the development of alternative strategies for effective drug delivery to improve the outcome of patients suffering from deadly diseases such as cancer. Nanoparticles, in particular layered double hydroxide (LDH) nanoparticles, have great potential as nanocarriers of chemotherapeutic molecules. …”
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14314
Feasibility and Efficacy of S-Adenosyl-L-methionine in Patients with HBV-Related HCC with Different BCLC Stages
Published 2016-01-01“…To understand the feasibility and efficacy of treatment with SAMe in patients with hepatitis B-related HCC with different Barcelona Clinic Liver Cancer (BCLC) stages. Methods. We retrospectively enrolled 697 patients with BCLC early-stage (stages 0-A) and advanced-stage (stages B-C) HCC who underwent SAMe therapy (354 cases) or no SAMe therapy (343 cases). …”
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14315
A bird’s-eye view of the biological mechanism and machine learning prediction approaches for cell-penetrating peptides
Published 2025-01-01“…Creating drug delivery systems with CPP is associated with cancer, genetic disorders, and diabetes due to their unique chemical properties. …”
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14316
Medullary Thyroid Carcinoma with Micronodular Lung Metastases: A Case Report with an Emphasis on the Imaging Findings
Published 2010-01-01“…Here, we present a case of a micronodular radiographic pattern in metastatic medullary thyroid cancer in order to enhance awareness of the disease process. …”
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14317
The role of endoscopic ultrasound in the diagnosis and characterization of focal liver lesions
Published 2024-12-01“…These lesions are frequently found in patients with colorectal cancer, cirrhosis, or incidentally during evaluations for abdominal pain or shock. …”
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14318
Human microbiome, applied to clinical practice
Published 2018-08-01“…The model of bacterial involvement in colorectal cancer progression is under study. Besides, the increasing attention of doctors and scientists is attracted to the issue intestinal microflora changes at antibiotic treatment. …”
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14319
Follicular Thyroid Carcinoma Metastatic to the Kidney: Report of a Case with Cytohistologic Correlation
Published 2015-01-01“…Here we report a case of a 45-year-old female who underwent thyroidectomy for thyroid cancer and presented 20 years later with a left renal mass. …”
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14320
EUS Morphology Is Reliable in Selecting Patients with Mucinous Pancreatic Cyst(s) Most Likely to Benefit from Surgical Resection
Published 2017-01-01“…None of the patients without any of these morphologic features had cancer. Conclusions. In patients with mucinous pancreatic cyst(s), focal wall thickening, cyst size ≥ 3 cm, and PD dilation as assessed by EUS can help identify advanced mucinous cysts which require surgery and should routinely be evaluated during EUS surveillance.…”
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