Novel cis-Pt(II) Complexes with Alkylpyrazole Ligands: Synthesis, Characterization, and Unusual Mode of Anticancer Action by Jana Kasparkova, Hana Kostrhunova, Vojtech Novohradsky, Аlexey A. Logvinov, Viktor V. Temnov, Nataliya E. Borisova, Tatiana A. Podrugina, Lenka Markova, Pavel Starha, Alexey. A. Nazarov, Viktor Brabec

“…It is noteworthy that while chlorido complexes display activity in a variety of cancer cell lines comparable to cisplatin, iodido complexes are considerably more potent due to their enhanced hydrophobicity and consequently enhanced cellular accumulation. …”
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Monoclonal Antibodies for Non-Hodgkin's Lymphoma: State of the Art and Perspectives by Giulia Motta, Michele Cea, Eva Moran, Federico Carbone, Valeria Augusti, Franco Patrone, Alessio Nencioni

“…Monoclonal antibodies have been the most successful therapeutics ever brought to cancer treatment by immune technologies. The use of monoclonal antibodies in B-cell Non-Hodgkin's lymphomas (NHL) represents the greatest example of these advances, as the introduction of the anti-CD20 antibody rituximab has had a dramatic impact on how we treat this group of diseases today. …”
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Synthesis of Arginase Inhibitors: An Overview by Maria Cristina Molaro, Chiara Battisegola, Marica Erminia Schiano, Mariacristina Failla, Maria Grazia Rimoli, Loretta Lazzarato, Konstantin Chegaev, Federica Sodano

“…In recent decades, the abnormal expression of ARG-1 or ARG-2 has been reported to be increasingly linked to a variety of diseases, including cardiovascular disease, inflammatory bowel disease, Alzheimer’s disease, and cancer. Therefore, considering the current relevance of this topic and the need to address the growing demand for new and more potent ARG inhibitors in the context of various diseases, this review was conceived. …”
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Colposcopy Value in Young Child-bearing Women: Is New Recommendations Necessary? by Fahimeh Sabet, Avishan Aminizad, Fariba Behnamfar, Tajossadat Allameh, Seyedeh Ghazal Shahrokh, Rostami Koushan, Amirmohammad Taravati, Leila Mousavi Seresht

“…Background: Cervical cancer is a common malignancy in women and HPV infection is directly linked to it and can be considerably prevented through routine screenings. …”
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The Role of Gut Microbiota in Tumor Immunotherapy by Miao Wu, Jiawei Bai, Chengtai Ma, Jie Wei, Xianjin Du

“…Some bacteria help fight tumors by activating immunity, while some bacteria mediate immunosuppression to help cancer cells escape from the immune system. More and more studies have revealed that the effects and complications of tumor immunotherapy are related to the composition of the gut microbiota. …”
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Current advancements in microneedle technology for therapeutic and biomedical applications by Olivia Sen, Poulami Poddar, Poulami Sarkar, Sanchita Das, Sreejan Manna

“…Silicon, stainless steel, polymers, coating materials, biodegradable materials, several crosslinking techniques and biosensing devices are used to fabricate microneedles. can be employed as a leading novel technology for drug administration, vaccinations, cosmetics, diagnostics, tissue engineering, cancer studies, and wound care. This review narrates the fabrication techniques of microneedles alongside its applications in drug delivery and biomedical field including sensory applications.…”
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Role of the Surgical Method in Development of Postoperative Cholangiocarcinoma in Todani Type IV Bile Duct Cysts by Hong-tian Xia, Tao Yang, Bin Liang, Jian-ping Zeng, Jia-hong Dong

“…Radical resection of both intra- and extrahepatic cysts combined with hepatic resection and Roux-en-Y hepaticojejunostomy is associated with a reduced risk of subsequent cancer development. Procedures in which radical cyst excision is not performed are associated with a greater risk of subsequent malignancy.…”
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The quantitative characteristic of morphological and structural changes in the diverted regions of the large intestine by A. S. Akopyan, E. V. Manukyan, T. G. Bagdasaryan, A. F. Abramyan, A. A. Akopyan

“…Radical surgery at complicated forms of colorectal cancer frequently results in colostoma formation. …”
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Systemic inflammatory response index improves prognostic predictive value in intensive care unit patients with sepsis by Tuo Xu, Shuaiwei Song, Ke Zhu, Yin Yang, Chengyu Wu, Naixue Wang, Shu Lu

“…The systemic inflammatory response index (SIRI), a new inflammatory indicator, has shown good predictive value in chronic infection, stroke, and cancer. The purpose of this study was to investigate the connection between sepsis and SIRI and evaluate its predictive usefulness. …”
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Therapeutic Effects of Yoga in Reducing Stress in Hypertensive Patients by Evelyn Carolina Betancourt Rubio, Walter Alberto Vayas Valdiviezo, Daniela Abigail Cobo Álvarez

“…Evidence shows that stress contributes to the etiology of heart disease, cancer and stroke. <br /><strong>Objective:</strong> to evaluate the effects of yoga as a therapy in reducing stress in patients with high blood pressure. …”
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A cross-sectional survey on the effects of ambient temperature and humidity on health outcomes in individuals with chronic respiratory disease by Samantha Mekhuri, Shirley Quach, Caroline Barakat, Winnie Sun, Mika L Nonoyama

“…., asthma, sleep apnea, interstitial lung disease, lung cancer) and residing in Canada for ≥ 1 year. Negative responders to weather extremes were *a priori* defined as having a change of ≥ 2 points in the CAT…”
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In Vivo Evaluation of 1-O-(4-(2-Fluoroethyl-Carbamoyloxymethyl)-2-Nitrophenyl)-O-β-D-Glucopyronuronate: A Positron Emission Tomographic Tracer for Imaging β-Glucuronidase Activity... by Iněs F. Antunes, Hidde J. Haisma, Philip H. Elsinga, Aren van Waarde, Antoon T.M. Willemsen, Rudi A. Dierckx, Erik F.J. de Vries

“…The enzyme has also been investigated as a target in prodrug therapy for cancer. To investigate the role of β-GUS in pathologies and to optimize β-GUS-based prodrug therapies, we recently developed a positron emission tomographic (PET) tracer, 1-O-(4-(2-fluoroethyl-carbamoyloxymethyl)-2-nitrophenyl)-O-β-D>-glucopyronuronate ([ 18 F]FEAnGA), which proved to be selectively cleaved by β-GUS. …”
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The impact of age on genetic risk for common diseases. by Xilin Jiang, Chris Holmes, Gil McVean

“…We find evidence for age-varying relative risk profiles in nine diseases, including hypertension, skin cancer, atherosclerotic heart disease, hypothyroidism and calculus of gallbladder, several of which show evidence, albeit weak, for multiple distinct profiles of genetic relative risk. …”
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Optimal Analysis Method for Dynamic Contrast-Enhanced Diffuse Optical Tomography by Michael Ghijsen, Yuting Lin, Mitchell Hsing, Orhan Nalcioglu, Gultekin Gulsen

“…Hence, implementation of a combined MRI-DOT system to image ICG enhancement can potentially be a promising tool for breast cancer imaging.…”
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Successful pancreatic pseudocyst drainage using lumen-apposing metal stent for preventing re-rupture of splenic artery pseudoaneurysm by Takashi Ito, Tsukasa Ikeura, Koh Nakamaru, Masataka Masuda, Shinji Nakayama, Makoto Naganuma

“…A 59-year-old man presented with back pain, and contrast-enhanced computed tomography (CECT) revealed pancreatic tail cancer with multiple liver metastases. After three courses of chemotherapy, CECT revealed good response with shrinkage of the tumors. …”
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Genomic landscape and comparative analysis of tissue and liquid-based NGS in Taiwanese anaplastic thyroid carcinoma by Chun-Nan Yeh, Shu-Fu Lin, Chia-Ling Wu, Miaw-Jene Liou, I-Wen Chen, Chiao-Ping Chen, Ching-Fu Chang, Qi‑An Wang, Chiao-En Wu

“…Abstract Anaplastic thyroid carcinoma (ATC) is an aggressive cancer that requirements rapid diagnosis and multimodal treatment. …”
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Health and economic impact of caregiving on informal caregivers of people with chronic diseases in sub-Saharan Africa: A systematic review. by Ephraim Kisangala, Etheldreda Leinyuy Mbivnjo, Edward J D Webb, Barbara Barrett, Godfrey Zari Rukundo, Eve Namisango, Margaret Heslin

“…The articles were from all sub-regions of sub-Saharan Africa with more than half (25/47) of the studies focussing on caregivers for patients with cancer. Although the primary motivation for becoming caregivers was love and responsibility, the caring responsibilities described in twenty studies, had profound effects on the caregiver's lives. …”
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Spectrum of Renal Tumors Other Than Renal Cell Carcinoma with Emphasis on Cytomorphological, Immunohistochemical, and Cytogenetic Study by Soumya Alashetty, Priya Dharmalingam, Sindhu Ramamurthy, Bidadi Lingappa Kavitha, Siddappa Shanthala, Rajasab Subhan Ali

“…Materials and Methods: Data of 238 cases of ultrasound-guided renal FNAC performed in our tertiary cancer institute over 4 years were collected from the department registry. …”
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Unraveling relationship between the genetic polymorphism CYP2A13 and nicotine metabolism of male smokers in Medan, Indonesia by Noni Novisari Soeroso, Rozaimah Zain-Hamid, Syamsul Bihar, Chaliza Soliha, Fannie Rizki Ananda, Aida

“…CYP2A13, a key enzyme in nicotine and xenobiotic metabolism, is implicated in tobacco smoke-related lung cancer. Aim This study investigated the association between CYP2A13 genetic polymorphism and nicotine metabolism in male smokers in Medan, Indonesia. …”
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Development of a UPLC-MS/MS Method for the Quantification of VS-5584 and Its Application in Pharmacokinetic Studies in Rats by Chunling Zhou, Xiaoxin Li, Aiping He, Tianzhu Liu, Jinmiao Tian, Meihua Jiang, Lina Fang

“…VS-5584 is a small-molecular compound that showed equivalent activity against mTOR and all class I PI3K isoforms and demonstrated preclinical activity in diverse cancer cell lines and xenograft tumor model, and rational combination of VS-5584 and other target therapies achieved promising outcomes in oncology. …”
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