In vivo MRI visualization of growth and morphology in the orthotopic xenotrasplantation U87 glioblastoma mouse SCID model by E. L. Zavjalov, I. A. Razumov, L. A. Gerlinskaya, A. V. Romashchenko

“…Glioblastoma multiforme (GBM) is the most common and lethal type of brain cancer with the average lifespan of patients about 9–12 months. …”
Get full text

Effective and Safe Treatment of Risky Localized Liver Tumors Using Microwave Ablation in Patients with Comorbid Lung Diseases Unfit for Deep Anesthesia by Murat ASIK

“…Conclusions: Percutaneous MWA results in very low mortality and morbidity, coupled with high complete ablation rates for liver cancer. Most liver tumors can be treated safely and effectively with percutaneous MWA, even in cases of high-risk localization, without the need for deep anesthesia.…”
Get full text

Discovery of novel TACE inhibitors using graph convolutional network, molecular docking, molecular dynamics simulation, and Biological evaluation. by Muhammad Yasir, Jinyoung Park, Eun-Taek Han, Jin-Hee Han, Won Sun Park, Mubashir Hassan, Andrzej Kloczkowski, Wanjoo Chun

“…Vorinostat, originally an FDA-approved drug for cancer treatment, exhibited strong binding interactions with key TACE residues, suggesting its repurposing potential. …”
Get full text

Xerostomia: a silent burden for people receiving palliative care – a qualitative descriptive study by Emir Murphy Dourieu, Dominika Lisiecka, William Evans, Patricia Sheahan

“…Results The majority of participants (35/40) had cancer. Xerostomia was reported to have multiple physical, psychological, and daily life consequences. …”
Get full text

Clinical Presentation and Course of Crohn's Disease in Southeastern Ontario by William T. Depew, Jose Medeiros, Ivan T. Beck, Laurington R. Dacosta, Aubrey Groll

“…None of the patients had either large or small bowel cancer during the follow-up period and there were no deaths related directly to Crohn's disease, its complications or related surgery.…”
Get full text

Remodelling of the immune landscape by IFNγ counteracts IFNγ-dependent tumour escape in mouse tumour models by Vivian W. C. Lau, Gracie J. Mead, Zofia Varyova, Julie M. Mazet, Anagha Krishnan, Edward W. Roberts, Gennaro Prota, Uzi Gileadi, Kim S. Midwood, Vincenzo Cerundolo, Audrey Gérard

“…Our work thus serves mechanistic insight for the crosstalk between tumour IFNγ resistance and anti-tumour immunity, and implicates this regulation for future cancer therapy.…”
Get full text

A Pancreatic Head Tumor Arising as a Duodenal GIST: A Case Report and Review of the Literature by Fabian Bormann, Wolfgang Wild, Hüseyin Aksoy, Pius Dörr, Sanja Schmeck, Matthias Schwarzbach

“…We present a case of a sixty-four-year-old woman who presented with abdominal pain and cardialgia for a follow-up examination after breast cancer surgery. On laparotomy there was a 3 × 5 cm hypervascular mass arising from the pancreatic head with macroscopically no attachment to the duodenum. …”
Get full text

Structural Modifications Reveal Dual Functions of the C-4 Carbonyl Group in the Fatty Acid Chain of Ipomoeassin F by Arman Khosravi, Precious Nnamdi, Alexa May, Kelsey Slattery, Robert E. Sammelson, Wei Q. Shi

“…Ipomoeassin F (Ipom-F) is a plant-derived macrocyclic resin glycoside that potently inhibits cancer cell growth through blockage of Sec61-mediated protein translocation at the endoplasmic reticulum. …”
Get full text

DNA Cleavage, Cytotoxic Activities, and Antimicrobial Studies of Ternary Copper(II) Complexes of Isoxazole Schiff Base and Heterocyclic Compounds by Vijay Kumar Chityala, K. Sathish Kumar, Ramesh Macha, Parthasarathy Tigulla, Shivaraj

“…In vitro antitumor activity of Cu(II) complexes was assayed against human cervical carcinoma (HeLa) cancer cells and it was observed that few complexes exhibit good antitumor activity on HeLa cell lines. …”
Get full text

Metastatic Follicular Thyroid Carcinoma Secreting Thyroid Hormone and Radioiodine Avid without Stimulation: A Case Report and Literature Review by Syed A. Abid, Brendan C. Stack, Donald L. Bodenner

“…This is an extremely rare case of a patient with metastatic follicular thyroid cancer who continued to produce thyroid hormone and was iodine scan positive without stimulation after thyroidectomy and radioiodine (I-131) therapy. …”
Get full text

The significance of magnetized thermal radiation on the magnetohydrodynamic (MHD) behavior of Williamson hybrid ferrofluids over a stretching sheet by D. Thenmozhi, M. Eswara Rao, P.D. Selvi, RLV. Renuka Devi, S. Kiranmaiye, Ch. Nagalakshmi

“…The novelty of this work lies in its application of the Williamson nanofluid model to real-time medical applications, such as cancer treatment through magnetic hyperthermia, and its potential use in advanced biomedical devices.…”
Get full text

The Interaction of lncRNA-HEIH and lncRNA-HULC with HBXIP in Hepatitis B Patients by Lingjuan Ruan, Lifei Huang, Lilai Zhao, Qiang Wang, Xiaocheng Pan, Anmin Zhang, Qiuping Bai, Zongjun Lv

“…Many studies have shown that long noncoding RNAs (lncRNAs) that are highly expressed in HCC (lncRNA-HEIH) and highly upregulated in liver cancer (lncRNA-HULC) have been implicated in the development and progression of hepatitis B-related HC and HCC. …”
Get full text

A viabilidade da pratica de treinamento físico em pacientes com leucemia aguda: uma revisão sistemática by Alan Moraes, Claudio Battaglini, Douglas Smielewski, Ariany Vieira, Magnus Benetti

“…Pesquisas com pacientes oncohematológicos vêm mostrando que o treinamento físico possa ser capaz de minimizar os efeitos adversos do tratamento quimioterápico do câncer. Objetivo: Verificar a viabilidade de um programa estruturado de treinamento físico especificamente em pacientes com leucemia mielóide aguda e leucemia linfoide aguda durante o tratamento inicial da doença. …”
Get full text

Core Cross-linked Star Polymers for Temperature/pH Controlled Delivery of 5-Fluorouracil by Elizabeth Sánchez-Bustos, José M. Cornejo-Bravo, Angel Licea-Claverie

“…The prepared core cross-linked star polymers represent advanced drug delivery vehicles optimized for 5-FU with potential application in cancer treatment.…”
Get full text

Reaching Syrian migrants through Dutch municipal registries for hepatitis B and C point-of-care testing. by Chrissy P B Moonen, Elfi E H G Brouwers, Christian J P A Hoebe, Nicole H T M Dukers-Muijrers, Jamila Bouchaara, Inge H M van Loo, Casper D J den Heijer

“…Undetected chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) infections can lead to cirrhosis and liver cancer. Syrian migrants are the largest non-European migrant group in the Netherlands with HBV and HCV prevalence rates above 2%. …”
Get full text

Identification and Validation of TEAD Family’s Prognostic Effects and Immune Microenvironment Regulations in Glioma by Zhengyuan Huo, Shaorui Gu, Zheng Bian, Wenli Wang, Zhifeng Jiang

“…Functional analyses revealed TEAD involvement in cancer cell transcription. The high expression of TEADs was greatly related to the myeloid-derived suppressor cells (MDSCs) and regulatory T-cells (Tregs) infiltration. …”
Get full text

Identification of a Novel Prognostic Lymphangiogenesis-Related Signature Associated with Tumor Immunity for Guiding Therapy in Lung Adenocarcinoma by Juan Peng, Dan Liu, Hong-feng Zhang, Qi-hao Hu, Wen Chen, Juan Zou, Juan Zhang, Hui Li, An-bo Gao, Yu-kun Li

“…Lymphangiogenesis, an integral contributor to lymphatic metastasis, is a significant reason for the poor prognosis of cancer patients. Anti-lymphangiogenesis treatment is a promising novel therapeutic direction, especially for tumors resistant to conventional therapies. …”
Get full text

EMFF-Net: Edge-Enhancement Multi-Scale Feature Fusion Network by Xuhui Guan, Jiwang Zhou, Jian Chen, Xiaodan Xu, Yizhang Jiang, Kaijian Xia

“…According to medical research, colorectal polyps are considered typical precancerous lesions, making colonoscopic polyp images crucial for the early diagnosis of rectal cancer. However, variations in polyp size and shape, texture inconsistencies, and boundary ambiguities often pose significant challenges for polyp segmentation. …”
Get full text

A Case of De Novo CD5+ Disseminated Intravascular Large B-Cell Lymphoma Presenting as Multiorgan Failure by Daulath Singh, Devika Kapuria, Suparna Nanua, Rakesh Gaur

Get full text

Exploring the Mechanisms of Zhenbao Pills in the Treatment of Stroke through Network Pharmacology Combined with Mendelian Randomization by Yanhong Liu, Yunqi Hua, Xiaoe Jia

Get full text