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14141
Comprehensive Analysis of the Expression, Prognostic Value, and Immune Infiltration Activities of GABRD in Colon Adenocarcinoma
Published 2023-01-01“…Multiple lines of evidence point to the possibility that genetic variables and clinicopathological traits are connected to the onset and development of cancer. In the past, a number of studies have revealed that gamma-aminobutyric acid type A receptor subunit delta (GABRD) plays a role in the advancement of a number of different cancers. …”
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14142
Biphasic Chromatin Structure and FISH Signals Reflect Intranuclear Order
Published 2005-01-01“…Similarly, a genome-wide monoallelic replication may tilt the balance of heterozygosity resulting in aneusomy, initiating early events in malignant transformation and in predicting cancer mortality.…”
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14143
Semantic Modeling for SNPs Associated with Ethnic Disparities in HapMap Samples
Published 2014-03-01“…Our semantic modeling for ethnicity-specific SNPs showed interesting results in the three categories, including three diseases ("AIDS-associated nephropathy," "Hypertension," and "Pelvic infection"), one drug ("Methylphenidate"), and five pathways ("Hemostasis," "Systemic lupus erythematosus," "Prostate cancer," "Hepatitis C virus," and "Rheumatoid arthritis"). …”
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14144
Screening of multi deep learning-based de novo molecular generation models and their application for specific target molecular generation
Published 2025-02-01“…Moreover, we evaluated the performance of these NLP-based generation models and another new model architecture based on a selective state space and selected the best approach jointing a transfer learning strategy for de novo drug discovery to target L858R/T790M/C797S-mutant EGFR in non-small cell lung cancer.…”
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14145
Risk of Exposure to Trace Elements through the Application of Facial Makeup Powders
Published 2022-01-01“…Dermal exposure to trace elements from cosmetics resulted in a lifetime cancer risk (LCR) that was higher than what was considered tolerable (LCR >10−6) due to the presence of Pb, As, and Cr. …”
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14146
Gene Editing in Pluripotent Stem Cells and Their Derived Organoids
Published 2021-01-01“…Gene editing in PSCs creates visualized in vitro models, providing opportunities for examining mechanisms of known and unknown mutations and offering new possibilities for the treatment of cancer, genetic diseases, and other serious or refractory disorders. …”
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14147
Association between Obesity, Serum Lipids, and Colorectal Polyps in Old Chinese People
Published 2013-01-01“…Background. Colorectal cancer mostly arises from the polyps of colon. The aim of our study was to examine the association of body mass index (BMI) and serum lipids with the colorectal polyps in old Chinese people. …”
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14148
The Role of Physical Activity in Reducing Inflammation: Implications for Preventive Medicine
Published 2025-01-01“…Physical inactivity is associated with the development of various chronic diseases including cancer, cardiovascular, metabolic and neurodegenerative diseases [1]. …”
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14149
Pulmonary Artery Pseudoaneurysm: A Rare Cause of Fatal Massive Hemoptysis
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14150
Insights into the mechanism of antiproliferative effects of primaquine-cinnamic acid conjugates on MCF-7 cells
Published 2018-09-01“…In our previous paper, we showed that three primaquine-cinnamic acid conjugates composed of primaquine (PQ) residue and cinnamic acid derivatives (CADs) bound directly by an amide linkage (1) or through an acylsemicarbazide spacer (2 and 3) had significant growth inhibitory effects on some cancer cell lines. Compound 1 induced significant growth inhibition in the colorectal adenocarcinoma (SW620), human breast adenocarcinoma (MCF-7) and cervical carcinoma (HeLa) cell lines, while compounds 2 and 3 selectively inhibited the growth of MCF-7 cells. …”
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14151
Clinical outcomes and risk factors of post-polypectomy microperforation in patients with colorectal neoplasia: a case-control study
Published 2025-01-01“…Background: Colonoscopic polypectomy significantly reduces the incidence of colorectal cancer, but it carries potential risks, with colonic perforation being the most common and associated with significant morbidity. …”
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14152
A Universal Analysis Pipeline for Hybrid Capture-Based Targeted Sequencing Data with Unique Molecular Indexes
Published 2018-12-01“…First, we generated hybrid capture-based data using genomic DNA extracted from tumor tissues of colorectal cancer patients. Sequencing libraries were prepared and pooled together, and an 8-plexed capture library was processed to the enrichment step before 150-bp paired-end sequencing with Illumina HiSeq series. …”
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14153
An In Silico Approach for Evaluating a Fraction-Based, Risk Assessment Method for Total Petroleum Hydrocarbon Mixtures
Published 2012-01-01“…Furthermore, the results support the general methodology of mixture risk assessment to assess both cancer and noncancer risk values after the application of fractionation.…”
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14154
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14155
The zinc finger protein560(ZNF560) functions as a novel oncogenic gene in osteosarcoma
Published 2025-01-01“…Results: By analyzing data from both the GEO and the Cancer Genome Atlas (TCGA) databases, increased expression of ZNF560 in OS tissues was verified, which was significantly associated with poorer outcomes in osteosarcoma patients both in TCGA-SARC and our own OS cohorts. …”
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14156
Assistance for the Prescription of Nutritional Support Must Be Required in Nonexperienced Nutritional Teams
Published 2013-01-01“…The study included 120 patients bearing a surgical disease in 86.7% of cases and 10% of medical cases. 50% of the patients had cancer. Nutritional status was correctly evaluated in 38.3% by the initial doctors’ diagnosis—consistent with the software’s evaluation. …”
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14157
DCE-MRI and DWI Integration for Breast Lesions Assessment and Heterogeneity Quantification
Published 2012-01-01“…In order to better predict and follow treatment responses in cancer patients, there is growing interest in noninvasively characterizing tumor heterogeneity based on MR images possessing different contrast and quantitative information. …”
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14158
Applying multi-theory model to determine intentions to smoking cessation among male health worker smokers in Kabul, Afghanistan
Published 2025-01-01“…IntroductionSmoking causes lung cancer and a wide range of acute and chronic diseases annually throughout the world. …”
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14159
Comprehensive Analysis of the Role of SLC2A3 on Prognosis and Immune Infiltration in Head and Neck Squamous Cell Carcinoma
Published 2022-01-01“…SLC2A3 is upregulated in various cancer types and promotes proliferation, invasion, and metabolism. …”
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14160
Natural compounds in the management of polycystic ovary syndrome: a comprehensive review of hormonal regulation and therapeutic potential
Published 2025-02-01“…This disorder affects approximately 6–20% of individuals, primarily emerging during early adolescence, and considerably increases the risk of conditions such as impaired glucose tolerance, type 2 diabetes, endometrial cancer, cardiovascular diseases, dyslipidemia, and postpartum complications. …”
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