The impact of death and caring for the dying and their families on surgeons - an AI assisted systematic scoping review by Jun Rong Tan, Yun Ting Ong, Victoria Jia En Fam, Annushkha Sinnathamby, Nila Ravindran, Yaoyi Ng, Lalit Kumar Radha Krishna

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Synthetic Computed Tomography generation using deep-learning for female pelvic radiotherapy planning by Rachael Tulip, Sebastian Andersson, Robert Chuter, Spyros Manolopoulos

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MAAT: a new nonparametric Bayesian framework for incorporating multiple functional annotations in transcriptome-wide association studies by Han Wang, Xiang Li, Teng Li, Zhe Li, Pak Chung Sham, Yan Dora Zhang

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Protein tyrosine phosphatase delta is a STAT3-phosphatase and suppressor of metabolic liver disease by Thomas F Baumert, Charlotte Bach, Patrick Pessaux, Catherine Schuster, Frank Jühling, Sarah C Durand, Yujin Hoshida, Fabien Zoulim, Atish Mukherji, Naoto Fujiwara, Marine A Oudot, Armando Andres Roca Suarez, Michel L Tremblay, Barbara Testoni, Joachim Lupberger, Romain Parent, Laurent Mailly, Nassim Dali-Youcef, Emanuele Felli, Maria Saez-Palma, Julien Moehlin, Alessia Virzì, Nicolas Brignon, Eugenie Schaeffer, Romain Martin, Laura Meiss-Heydmann, Zakaria Boulahtouf, Lea Girard, Emma Osswald, Carole Jamey, Daniel Brumaru, Bhuvaneswari Koneru

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Ulcerative colitis: STRIDE-ing beyond symptoms with new standards by Shu Wen Tay, Kevin Kim Jun Teh, Tiing-Leong Ang, Malcolm Tan

“…Controlling the burden of disease activity also lowers the risk of developing colorectal cancer. Colorectal cancer screening now requires the use of dye-based agents and high-definition colonoscopy to improve the detection of colonic neoplasms.…”
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Characterization of the genomic landscape of canine diffuse large B-cell lymphoma reveals recurrent H3K27M mutations linked to progression-free survival by Anna Darlene van der Heiden, Raphaela Pensch, Sophie Agger, Heather L. Gardner, William Hendricks, Victoria Zismann, Shukmei Wong, Natalia Briones, Bryce Turner, Karin Forsberg-Nilsson, Cheryl London, Kerstin Lindblad-Toh, Maja Louise Arendt

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Mycochemistry, antioxidant, anticancer activity, and molecular docking of compounds of F12 of ethyl acetate extract of Astraeus asiaticus with BcL2 and Caspase 3 by Swapan Kumar Ghosh, Koushik Pandey, Madhuparna Ghosh, Pradip Kumar Sur

“…Abstract Globally the current research is going for cancer disease management by different strategies as frequency and severity of this disease are increasing day by day. …”
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Peripheral neuropathy in the phase 3 ASPEN study of Bruton tyrosine kinase inhibitors for Waldenström macroglobulinemia by Benjamin M. Heyman, Stephen S. Opat, Björn E. Wahlin, Meletios-Athanasios C. Dimopoulos, Jorge J. Castillo, Alessandra Tedeschi, Constantine S. Tam, Christian Buske, Roger G. Owen, Véronique Leblond, Judith Trotman, Gisoo Barnes, Wai Y. Chan, Jingjing Schneider, Heather Allewelt, Aileen Cohen, Jeffrey V. Matous

“…Health-related quality of life (HRQOL) was assessed using the validated European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30. Forty-nine patients with PN symptoms were included (zanubrutinib treated, n = 27; ibrutinib treated, n = 22). …”
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Harnessing nanoparticles for reshaping tumor immune microenvironment of hepatocellular carcinoma by JinSong Li, GuanBo Zhang, Gang Li, Jie Zhang, Zhi Yang, Lin Yang, ShiJie Jiang, JiaXing Wang

“…Abstract Hepatocellular carcinoma (HCC) is one of the most prevalent cancers, characterized by high morbidity and mortality rates. …”
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Colony-Forming and Cell Viability Assay to Assess Nanotoxicity of Maleic Acid and N-vinyl Caprolactam-Based Nanoarchitectures by Bekar Buse, Akar Burcu, Akan Handan Sevim, Can Hatice Kaplan

“…Nanocomposites significantly inhibited colony formation in both cancer cell lines, particularly in the HeLa cell line. …”
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Integrative analysis of SEPN1 in glioma: Prognostic roles, functional implications, and potential therapeutic interventions. by Zisong Wang, Danwen Wang, Xuanyu Wang, Yihang Xu, Yunhe Yuan, Yuxin Chen, Zhiqiang Li, Xiaoping Liu

“…<h4>Background</h4>SEPN1, a selenoprotein involved in redox regulation and endoplasmic reticulum stress response, has an unclear role in cancer. This study aims to investigate the expression, prognostic significance, and tumor microenvironment (TME) relevance of SEPN1 across pan-cancer, with a particular focus on glioma.…”
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Vitiligo and cutaneous malignancy: what is the risk? by Sahngeun Jenny Mun, Monisha Gupta

“…It is a long-held belief that patients with vitiligo have an increased risk for skin cancers due to the loss of melanin, a pigment which protects the skin against carcinogenesis. …”
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Comparison of Frozen and Final Pathology Results in Patients Operated for Endometrial Hyperplasia by Gonca Turker Ergun, Ugurcan Zorlu, Burak Elmas, Bengü Nur Baris Akcan, Gul Kurtaran, Kadir Cetinkaya, Melike Doganay

“… OBJECTIVE: Our study aimed to determine the frequency of endometrial cancer in patients undergoing surgery with a diagnosis of endometrial hyperplasia and to evaluate the concordance between preoperative diagnosis, frozen section examination, and final pathology results. …”
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A sensitive ERK fluorescent probe reveals the significance of minimal EGF-induced transcription by Zhang Weisheng, Jun Nakayama, Yukino Inomata, Shigeki Higashiyama, Toru Hiratsuka

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Targeting ceramide transfer protein sensitizes AML to FLT3 inhibitors via a GRP78-ATF6-CHOP axis by Xiaofan Sun, Yue Li, Juan Du, Fangshu Liu, Caiping Wu, Weihao Xiao, Guopan Yu, Xiaowei Chen, Robert Peter Gale, Hui Zeng

“…Abstract Sphingolipid, ceramide for example, plays an essential role in regulating cancer cell death. Defects in the generation and metabolism of ceramide in cancer cells contribute to tumor cell survival and resistance to chemotherapy. …”
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Modeling Radionuclide Transfer from Pasture to Milk in Kisoro, South- Western Uganda by Habakwiha V, Oruru B, Tumps Ireeta W

“…Comparing with the safe values of annual effective dose equivalent in foodstuffs of 0.14 mSv y l-1 which translates to excess cancer risk of 0.42 10-3, these contributions to radiological effects only account for about 1.5% of the total safe value of excess lifetime cancer risk, therefore, radionuclide transfer from pasture to milk causes a minimal radiation hazard to the milk consumers in Kisoro District.…”
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18F-FDG PET/CT assessment of metabolic tumor burden predicts survival in patients with metastatic posterior uveal melanoma by Tine Gadegaard Hindso, Torben Martinussen, Camilla Wium Bjerrum, Sune Høgild Keller, Annika Loft, Mette Bagger Sjøl, Kristoffer Nissen, Carsten Faber, Marco Donia, Inge Marie Svane, Eva Ellebaek, Steffen Heegaard, Jens Folke Kiilgaard, Karine Madsen

“…Abstract The prognostic value of metabolic tumor burden parameters obtained from 18F-FDG PET/CT imaging was evaluated in this retrospective national multicenter study of patients with metastatic posterior uveal melanoma (PUM) and compared to the largest diameter of the largest metastatic lesion (LDLM) and the American Joint Committee on Cancer (AJCC) staging system. The Maximal Standard Uptake Value (SUVmax), Metabolic Tumor Volume (MTV), and Total Lesion Glycolysis (TLG) were obtained in 106 patients. …”
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Personalized treatment strategies for breast adenoid cystic carcinoma: A machine learning approach by Sakhr Alshwayyat, Mahmoud Bashar Abu Al Hawa, Mustafa Alshwayyat, Tala Abdulsalam Alshwayyat, Siya sawan, Ghaith Heilat, Hanan M. Hammouri, Sara Mheid, Batool Al Shweiat, Hamdah Hanifa

“…Background: Breast adenoid cystic carcinoma (BACC) is a rare subtype of breast cancer that accounts for less than 0.1 % of all cases. …”
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Clinical outcomes after immune checkpoint inhibitor-associated acute kidney injury: a cohort study by Vin-Cent Wu, Ting-Ya Yang, Min-Hsiang Chuang, Hong-Min Lin, Heng-Chih Pan, Yun Chou, Jui-Yi Chen

“…Objectives Immune checkpoint inhibitors (ICPi) have significantly improved survival for patients with advanced cancers. However, the occurrence of ICPi-associated acute kidney injury (AKI) and its clinical impact remains unclear. …”
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Synchronous multiple myeloma and lung adenocarcinoma: A clinical series by Fang Ye, Huan Wang, Ningning Li, Aijun Liu, Wenming Chen

“…Rarely, MM and lung cancer are synchronously present in the same patient. …”
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