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12621
Levels and associated factors for early cessation of EBF among under six month children in Ethiopia
Published 2024-12-01“…Premature discontinuation can lead to risks of malnutrition, infections, impaired brain development, and increase the maternal susceptibility to breast and ovarian cancers. This study aimed to identify Multi-level risk factors for early termination of EBF for infants. …”
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12622
Assessment of residential exposures to agricultural pesticides: A scoping review.
Published 2020-01-01“…Of these, 98 (64.9%) were epidemiological studies investigating possible links between pesticide exposure and the onset of adverse health effects, principally cancers and reproductive outcomes. They predominantly used Geographic Information Systems and sometimes surveys or interviews to calculate surrogate exposure metrics, the most common being the amounts of pesticides applied or the surface area of crops around the dwelling. …”
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12623
Tracheostomy care quality improvement in low- and middle-income countries: A scoping review.
Published 2023-01-01“…Tracheostomy is a lifesaving, essential procedure performed for airway obstruction in the case of head and neck cancers, prolonged ventilator use, and for long-term pulmonary care. …”
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12624
Sex Differences in the Relation between Comorbidities and Prognosis in Hospitalized Patients with COVID-19
Published 2022-01-01“…Data on preexisting comorbid NCDs including hypertension, coronary heart disease (CHD), diabetes mellitus (DM), cancers, chronic renal disease (CRD), and chronic respiratory disease were collected through self-reported questionnaires. …”
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12625
Fulminant Diabetes in a Patient with Advanced Melanoma on Nivolumab
Published 2018-01-01“…Anti-PD-1 immunotherapy is effective in cancers refractory to standard chemotherapy. These agents can precipitate autoimmune disorders. …”
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12626
CRIP1 inhibits cutaneous melanoma progression through TFAM-mediated mitochondrial biogenesis
Published 2025-02-01“…CRIP1 (cysteine-rich protein 1) has been reported to be associated with malignant progression of several cancers. However, the biological function and underlying mechanisms of CRIP1 in melanoma progression are largely unknown. …”
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12627
iNOS Promotes the Development of Osteosarcoma via Wnt/β-Catenin Pathway
Published 2021-01-01“…Inducible nitric oxide synthase (iNOS), accompanied with protumor and antitumor activity, has been studied in multiple cancers. However, the role of iNOS expression in osteosarcoma (OS) is far from being fully understood. …”
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12628
Exploring novel and potent glycogen synthase kinase-3β inhibitors through systematic drug designing approach
Published 2025-02-01“…Abstract Significant implications of glycogen synthase kinase-3β (GSK-3β) have been reported in various neuronal disorders and malignant cancers. GSK-3β modulates diverse protein targets through phosphorylation, and its aberrant activity leads to neurological complications as well as tumour onset. …”
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12629
Chromatin remodeling in oligodendrogenesis
Published 2021-09-01“…Mutations in the genes encoding proteins of the remodeling complexes are often accompanied by serious disorders at early stages of embryogenesis and are frequently identified in various cancers. According to the domain arrangement of the ATP-hydrolyzing subunit, most of the identified ATP-dependent chromatin-remodeling complexes are classified into four subfamilies: SWI/SNF, CHD, INO80/SWR, and ISWI. …”
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12630
Performance Assessment of a Permeable Reactive Barrier on Reducing Groundwater Transport of Nitrate from an Onsite Wastewater Treatment System
Published 2025-01-01“…Elevated concentrations of nitrate in potable water supplies have been linked to negative health outcomes such as methemoglobinemia and various cancers. Groundwater can become contaminated with nitrate from sources including onsite wastewater treatment systems (OWTSs). …”
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12631
Overexpression of PAX8-AS1 Inhibits Malignant Phenotypes of Papillary Thyroid Carcinoma Cells via miR-96-5p/PKN2 Axis
Published 2021-01-01“…LncRNA PAX8-AS1, a tumor suppressor associated with various human cancers, has been reported to be relevant to the regulation of all sorts of cellular processes. …”
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12632
Factors Leading To Early Versus Late Presentation In Patients With Neck Masses
Published 2023-12-01“…This study helped to identify the role of various suspected risk factors for late presentation in head and neck cancers in an attempt to reinforce or negate their importance which will help to guide the formation of screening protocols thereby improving morbidity, and mortality and reducing financial costs. …”
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12633
Genome-Wide Expression Difference of MicroRNAs in Basal Cell Carcinoma
Published 2021-01-01“…Functional analysis of predicted target genes of DEMs in BCCs shows that these miRNAs are primarily involved in various types of cancers, immune response, epithelial growth, and morphogenesis, as well as energy production and metabolism, indicating that BCC development is caused, at least in part, by changes in miRNA regulation for biological and disease processes. …”
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12634
Comprehensive analysis of publications concerning combinations of immunotherapy and targeted therapies for hepatocellular carcinoma: a bibliometric study
Published 2025-02-01“…The authors Kudo Masatoshi and Hatanaka Takeshi were the most prolific, each with nine publications. The journal Cancers emerged as the top publisher, with 48 relevant articles and an Impact Factor of 5.2 in 2022. …”
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12635
Hyperlipidemia May Synergize with Hypomethylation in Establishing Trained Immunity and Promoting Inflammation in NASH and NAFLD
Published 2021-01-01“…Our findings provide novel insights on the synergies between hyperlipidemia and hypomethylation in establishing TI and promoting inflammation in NASH and NAFLD progression and novel targets for future therapeutic interventions for NASH and NAFLD, metabolic diseases, transplantation, and cancers.…”
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12636
ROS-ERK Pathway as Dual Mediators of Cellular Injury and Autophagy-Associated Adaptive Response in Urinary Protein-Irritated Renal Tubular Epithelial Cells
Published 2021-01-01“…ERK, an extracellular signal-regulated protein kinase, is involved in various biological responses, such as cell proliferation and differentiation, cell morphology maintenance, cytoskeletal construction, apoptosis, and canceration of cells. In this study, we focused on ERK pathway on cellular injury and autophagy-associated adaptive response in urinary protein-irritated renal tubular epithelial cells and explored the potential mechanisms underlying it. …”
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12637
Primary Fallopian Tube Carcinoma: Results of a Single-Institutional Retrospective Analysis of 17 Patients with Evaluation of Staging and Prognostic Factors
Published 2021-12-01“… OBJECTIVE: Primary carcinoma of the fallopian tubes is one of the less common gynecological cancers. It constitutes (0.14-0.18%) of gynecological malignancies. …”
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12638
Effect of bortezomib on the treatment of multiple myeloma: a systematic review protocol
Published 2022-06-01“…Introduction Multiple myeloma (MM) is an incurable malignant neoplasm that accounts for approximately 1% of all cancers and 10% of haematological malignancies. Bortezomib is one of the most commonly used medications in first-line treatment and subsequent relapses, either as a single agent or in combination with other therapies. …”
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12639
CD4+CD25highCD127low/−FoxP3+ Regulatory T Cell Subpopulations in the Bone Marrow and Peripheral Blood of Children with ALL: Brief Report
Published 2018-01-01“…CD4+CD25highCD127low/−FoxP3+ regulatory T cells (Tregs) are currently under extensive investigation in childhood acute lymphoblastic leukemia (ALL) and in other human cancers. Usually, Treg cells maintain the immune cell homeostasis. …”
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12640
Liver Resection Promotes (Regulates) Proinflammatory Cytokines in Patients with Hepatocellular Carcinoma
Published 2021-01-01“…Several animal studies have shown the roles of cytokines in regulating liver regeneration following liver resection (LR), which is a type of surgery designed to remove cancerous tumors from the liver. This study investigated how the expressions and serum levels of some pro- and anti-inflammatory cytokines in patients with hepatocellular carcinoma (HCC) were changed during LR. …”
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