Network Graph Analysis of Gene-Gene Interactions in Genome-Wide Association Study Data by Sungyoung Lee, Min-Seok Kwon, Taesung Park

“…Most common complex traits, such as obesity, hypertension, diabetes, and cancers, are known to be associated with multiple genes, environmental factors, and their epistasis. …”
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Better understanding the phenotypic effects of drugs through shared targets in genetic disease networks by Elena Díaz-Santiago, Aurelio A. Moya-García, Jesús Pérez-García, Raquel Yahyaoui, Raquel Yahyaoui, Christine Orengo, Florencio Pazos, James R. Perkins, James R. Perkins, James R. Perkins, Juan A. G. Ranea, Juan A. G. Ranea, Juan A. G. Ranea, Juan A. G. Ranea

“…The top results include phenotype-drug associations that represent intended effects, particularly for cancers such as chronic myelogenous leukemia, which was linked with nilotinib. …”
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Fucosylated haptoglobin promotes inflammation via Mincle in sepsis: an observational study by Taylor Roh, Sungeun Ju, So Young Park, Yeonghwan Ahn, Jiyun Chung, Miyako Nakano, Gyoungah Ryu, Young Jae Kim, Geumseo Kim, Hyewon Choi, Sung-Gwon Lee, In Soo Kim, Song-I Lee, Chaeuk Chung, Takashi Shimizu, Eiji Miyoshi, Sung-Soo Jung, Chungoo Park, Sho Yamasaki, Seung-Yeol Park, Eun-Kyeong Jo

“…Despite extensive research on Hp glycosylation as a glyco-biomarker for cancers, understanding glycosylated modifications of Hp in sepsis patients (SPs) remains limited. …”
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Parathyroid Carcinoma in the Setting of Tertiary Hyperparathyroidism: Case Report and Review of the Literature by Federico Cappellacci, Fabio Medas, Gian Luigi Canu, Maria Letizia Lai, Giovanni Conzo, Enrico Erdas, Pietro Giorgio Calò

“…Parathyroid carcinoma is one of the rarest cancers in normal population, and it is extremely uncommon in the setting of tertiary hyperparathyroidism. …”
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Eupalinolide B inhibits periodontitis development by targeting ubiquitin conjugating enzyme UBE2D3 by Wenhua Kuang, Ruishen Zhuge, Ping Song, Letai Yi, Shujie Zhang, Ying Zhang, Yin Kwan Wong, Ruixing Chen, Junzhe Zhang, Yuanbo Wang, Dandan Liu, Zipeng Gong, Peili Wang, Xiangying Ouyang, Jigang Wang

“…Eupalinolide B (EB) is a sesquiterpenoid natural product extracted from Eupatorium lindleyanum and has been reported as a potential drug for cancers and immune disorders. Here, we explored the ameliorative effects and underlying molecular mechanism of EB on periodontitis for the first time. …”
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Risk Factors and Predictive Model for Disseminated Intravascular Coagulation in Patients with Multiple Myeloma by Rong Bao MM, Mengtong Fan MM, Min Hu MM, Ling Li BD,   Hasichaolu BD

“…Objectives Multiple myeloma (MM) is a hematologic malignancy comprising approximately 10% of all blood cancers. Patients with MM are at risk for disseminated intravascular coagulation (DIC), a serious complication characterized by systemic coagulation activation, leading to microthrombi, organ dysfunction, and severe bleeding. …”
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Targeting the activated allosteric conformation of the endothelin receptor B in melanoma with an antibody-drug conjugate: mechanisms and therapeutic efficacy by Amaury Herbet, Marie Hautière, Frédéric Jean-Alphonse, Delphine Vivier, Christophe Leboeuf, Narciso Costa, Aloïse Mabondzo, Guilhem Bousquet, Franck Denat, Eric Reiter, Didier Boquet

“…Abstract Background Endothelin 1 receptors are one of the drivers of tumor progression in many cancers. Inhibition of their signaling pathways with antagonist drugs has been the subject of numerous clinical trials, but the results have not met expectations probably due to the high endothelin concentrations in the tumor microenvironment and their unusually high affinity for their receptors. …”
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Chromosomal Changes in relation to Clinical Outcome in Larynx and Pharynx Squamous Cell Carcinoma by Mario Hermsen, Marta Alonso Guervós, Gerrit Meijer, Paul van Diest, Carlos Suárez Nieto, Cesar Alvarez Marcos, Andrés Sampedro

“…Here we present Results of CGH analysis of 56 clinically well-characterized set of head and neck cancers, consisting of larynx and pharynx only. The aim was to find possible associations with clinical outcome. …”
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Nurses’ Knowledge of Palliative Care in the Pneumological Hospital by Inarvis Medina González, Elicerio Jorge Chacón Reyes, Odalys Tomaida Hernández Quintero

“…Fifty four point five percent consider that palliative care should not be provided at home; 63.6% believe that they should not be provided to patients with chronic non-cancerous diseases in advanced stages; 69.9% suggest that mixed therapies should not be used for pain management; 51.5% do not consider that breathing techniques should be used to control dyspnea. …”
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Major heavy metals and human gut microbiota composition: a systematic review with nutritional approach by Mahsa Rezazadegan, Bita Forootani, Yeganeh Hoveyda, Niloufar Rezazadegan, Reza Amani

“…Evidently, it is related to leaky gut, oxidative stress, and several diseases such as inflammatory bowel disease and cancers. Probiotic treatment and nutritional strategies such as high fiber intake and following antioxidant-rich diets should be considered in terms of HMs exposure.…”
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Mast cells: key players in digestive system tumors and their interactions with immune cells by Feihong Shu, Jie Yu, Youjia Liu, Fang Wang, Guoyou Gou, Min Wen, Chen Luo, Xianmin Lu, Yanxia Hu, Qian Du, Jingyu Xu, Rui Xie

“…It also explores the prognostic significance of mast cells in patients with various gastrointestinal cancers at different stages of the disease. Additionally, the article investigates the interactions between mast cells and immune cells, as well as the potential relationships among intratumoral bacteria, immune cells, and mast cell within digestive system microenvironment. …”
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Rapid Screening Method for Detecting Ethinyl Estradiol in Natural Water Employing Voltammetry by Chalder Nogueira Nunes, Lucas Ely Pauluk, Maria Lurdes Felsner, Vanessa Egéa dos Anjos, Sueli Pércio Quináia

“…17α-Ethinyl estradiol (EE2), which is used worldwide in the treatment of some cancers and as a contraceptive, is often found in aquatic systems and is considered a pharmaceutically active compound (PhACs) in the environment. …”
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Extracellular Vesicle-Encapsulated MicroRNA-375 from Bone Marrow-Derived Mesenchymal Stem Cells Inhibits Hepatocellular Carcinoma Progression through Regulating HOXB3-Mediated Wnt/... by Zhaoxia Yu, Ju Liu, Qiqi Fan, Jun Yu, Xiaoting Ren, Xiaobin Wang

“…Nowadays, microRNA-375 (miR-375) has been implicated in many types of cancers, including hepatocellular carcinoma (HCC), and the functions of miRNAs encapsulated by extracellular vesicles (EV) in HCC progression have also been extensively investigated. …”
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Meta-analysis of risk factors for postoperative lower extremity deep vein thrombosis in patients with gynecologic malignancies by Danzhu Gong, Qi Wang

“…IntroductionThis study aims to elucidate the risk factors associated with postoperative lower extremity deep vein thrombosis (DVT) in patients afflicted with gynecologic malignancies.MethodsA comprehensive search was conducted across CNKI, CQVIP, Wanfang, and PubMed databases for literature published from January 1, 2024, concerning the risk factors for postoperative DVT in patients with gynecologic cancers. Two researchers independently and objectively screened, extracted, and evaluated the pertinent data. …”
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Effect of Interleukin and Hepcidin in Anemia of Chronic Diseases by Maha F. Yacoub, Hala Fouad Ferwiz, Fadwa Said

“…Anemia of chronic disease (ACD) also termed as the anemia of inflammation has been found to be associated with inflammations, chronic infections, and cancers, particularly in old age. Recent studies revealed that interleukin-6 (IL-6), a proinflammatory cytokine, and hepcidin, an antimicrobial hepatic peptide, play a key role in ACD pathogenesis. …”
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HER2 Negative Mammary Paget’s Disease or In Situ Melanoma? A Case Report and Review of the Literature by Luana-Andreea Boșoteanu, Mariana Așchie, Cristian Ionuţ Orǎșanu, Mădălina Boșoteanu

“…Mammary Paget’s disease (MPD) is a rare histological condition, accounting for 1-4% of female breast cancers, which may appear either independently (1.4-13% of the cases), or in association with an in situ or invasive ductal carcinoma (approximately 90% of the cases). …”
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Is neutropenic fever an obstacle to effective stem cell harvesting? by Semih Başcı, Ersin Bozan, Samet Yaman, Bahar Uncu Ulu, Mehmet Bakırtaş, Tuğçe Nur Yiğenoğlu, Ali Kılınç, Nurgül Özcan, Mehmet Sinan Dal, Merih Kızıl Çakar, Fevzi Altuntaş

“…INTRODUCTION: Autologous stem cell transplantation (ASCT) is a well-established consolidation treatment for many hematologic cancers which delivers prolonged survival. A subset of patients’ adequate stem cell harvest is not achievable with a solitary use of granulocyte colony-stimulating agents (G-CSF). …”
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Differential expression of “A Disintegrin and Metalloproteinase 10” in hepatocellular carcinoma and the noncancerous hepatic tissues: Contribution to HCV-promoted hepatocarcinogene... by Amal Abd El Hafez, Basem H. Elesawy, Heba S. E. I. Hany

“…Background: A disintegrin and metalloproteinases (ADAMs) have emerged as therapeutic targets in many cancers. ADAM10 was particularly studied in hepatocellular carcinoma (HCC) for its potential role in hepatocarcinogenesis and HCC progression. …”
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Histological risk score and its role in predicting recurrence in early-stage oral squamous cell carcinomas by Daphne Fonseca, Rashmi Khemani, Mohan K. Pasam, Ravindranath Tagore, B. Vishal Rao, Suseela Kodandapani, Chandrasekhara Rao, K. V. V. N. Raju, T Subramanyeshwar Rao

“…Context: Oral squamous cell carcinoma (OSCC) comprises more than 90% of oral cancers and is the most common carcinoma affecting the oral cavity. …”
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Usual prevention in unusual settings: A scoping review of place-based health interventions in public-facing businesses. by Jack Tsai, Nicholas A McCann

“…These 42 studies were categorized based on health conditions of focus, including cardiovascular health (12 studies); HIV (6 studies); diabetes (5 studies); cancers (13 studies); and all other conditions (14 studies). …”
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