NFIB-Mediated lncRNA PVT1 Aggravates Laryngeal Squamous Cell Carcinoma Progression via the miR-1301-3p/MBNL1 Axis by Tian Tang, Feng Zeng

“…Laryngeal squamous cell carcinoma (LSCC) is one of the most common malignant tumors of head and neck cancers. In the past decades, although the therapy strategies of LSCC have made considerable improvement, the terrible outcomes of LSCC still bring an enormous burden to the world health care system. …”
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Metastatic Breast Carcinoma to the Prostate Gland by Meghan E. Kapp, Giovanna A. Giannico, Mohamed Mokhtar Desouki

“…Cancer of the male breast is an uncommon event with metastases to the breast occurring even less frequently. …”
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Regulation and Function of the Peg3 Imprinted Domain by Hongzhi He, Joomyeong Kim

“…The Peg3 domain also displays some unique features, including YY1-mediated regulation of transcription and imprinting; conversion and adaptation of several protein-coding members as ncRNA genes during evolution; and its close connection to human cancers through the potential tumor suppressor functions of Peg3 and Usp29. …”
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Integrins and Their Extracellular Matrix Ligands in Lymphangiogenesis and Lymph Node Metastasis by Jie Chen, J. Steven Alexander, A. Wayne Orr

“…Lymphangiogenesis inhibitors reduce lymph node metastasis, the leading indicator of poor prognosis, whereas inducing lymphangiogenesis promotes lymph node metastasis even in cancers not prone to lymphatic dissemination. Recent works highlight a role for integrins in lymphangiogenesis and suggest that integrin inhibitors may serve as therapeutic targets to limit lymphangiogenesis and lymph node metastasis. …”
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Multiple Functions of Phosphoinositide-3 Kinase Enhancer (PIKE) by Chi Bun Chan, Keqiang Ye

“…Interestingly, the PIKE gene (CENTG1) is also amplified in a variety of human cancers and enhances Akt activity, leading to their resistance against apoptosis and invasion. …”
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Transcriptional Regulators of Claudins in Epithelial Tight Junctions by Niamat Khan, Abdul R. Asif

“…Altered function of claudins is implicated in different form of cancers, inflammatory bowel diseases (IBDs), and leaky diarrhea. …”
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Multifaceted functions of the Wilms tumor 1 protein: From its expression in various malignancies to targeted therapy by Qing Nian, Yan Lin, Jinhao Zeng, Yanna Zhang, Rongxing Liu

“…This article provides information on the roles of WT1 in the pathogenesis of different cancers and provides insights into drugs and immunotherapies targeting WT1. …”
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Lipid Antigens: Revealing the Hidden Players in Adaptive Immune Responses by Tamana Eskandari, Yasamin Eivazzadeh, Fatemeh Khaleghinia, Fatemeh Kashi, Valentyn Oksenych, Dariush Haghmorad

“…These advancements have paved the way for lipid-based vaccines and immunotherapies through the application of nanoparticles and synthetic lipid antigens designed to boost immune responses against cancers and infectious diseases. Lipid trafficking, CD1 molecule interactions, and the immune system’s response to lipid antigens are yet to be completely understood, particularly in the context of autoimmunity and microbial infections. …”
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Artificial intelligence links CT images to pathologic features and survival outcomes of renal masses by Ying Xiong, Linpeng Yao, Jinglai Lin, Jiaxi Yao, Qi Bai, Yuan Huang, Xue Zhang, Risheng Huang, Run Wang, Kang Wang, Yu Qi, Pingyi Zhu, Haoran Wang, Li Liu, Jianjun Zhou, Jianming Guo, Feng Chen, Chenchen Dai, Shuo Wang

“…Improving the diagnosis of benign renal masses and distinguishing aggressive cancers from indolent ones is key to better treatment selection. …”
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Expressions of CXCL12/CXCR4 in Oral Premalignant and Malignant Lesions by Juan Xia, Na Chen, Yun Hong, Xiaobing Chen, Xiaoan Tao, Bin Cheng, Yulei Huang

“…The chemokine receptor CXCR4 and its ligand CXCL12 have been suggested to play important roles in the initiation or progression of cancers. The goal of the present study was to investigate alterations of CXCL12/CXCR4 in oral premalignant lesions and oral squamous cell carcinoma (OSCC). …”
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The Skin-Lightening Power of Tirbanibulin 1% Ointment by Federica Li Pomi, Andrea d’Aloja, Michelangelo Rottura, Mario Vaccaro, Francesco Borgia

“…Methods We report a single-center retrospective study of patients affected by solar lentigines (SLs) and AKs in the context of field cancerization treated with tirbanibulin 1% ointment. …”
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Recent Advances, Research Trends, and Clinical Relevance of Hyaluronic Acid Applied to Wound Healing and Regeneration by Gloria Huerta-Ángeles, Edgar Mixcoha

“…The synthesis/catabolism of HA is critical in several pathologies and has been used as a marker for the prognosis of cancers. Among its physiological roles, HA is used for wound healing applications. …”
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Using Health Utility Index (HUI) for Measuring the Impact on Health-Related Quality of Life (HRQL) Among Individuals with Chronic Diseases by Frank Mo, Bernard C.K. Choi, Felix C.K. Li, Joav Merrick

“…Urinary incontinence, Alzheimer/other dementia, effects of stroke, cancers, thyroid condition, and back problems have a moderate impact. …”
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True Lies: The Double Life of the Nucleotide Excision Repair Factors in Transcription and DNA Repair by Nicolas Le May, Jean-Marc Egly, Frédéric Coin

“…NER defects lead to three genetic disorders that result in predisposition to cancers, accelerated aging, neurological and developmental defects. …”
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A Western Case of Intravascular Large B-Cell Lymphoma as Unusual Cause of Persistent Fever by Pier Paolo Piccaluga, Stefania Paolini, Cristina Campidelli, Nicola Vianelli, Luigi Bolondi

“…Fever of unknown origin (FUO) is a common and challenging clinical condition that can be referred, among others, to infections, drug’s effects, various inflammatory disorders, and cancers. Among the latter, lymphomas can indeed cause fever, which is therefore accounted as a lymphoma-related sign in patients’ staging. …”
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Sarcoma primitivo de mama. Presentación de un caso by Lidia Torres Ajá

“…El sarcoma primitivo de la mama es el tumor maligno no epitelial menos frecuente, representa solamente menos del 1 % de los cánceres de la mama. Presentan un pronóstico sombrío con la presencia de metástasis tempranas, principalmente a nivel de pulmón y hueso y tienen una sobrevida muy pobre de solo 5 años. …”
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Pediatric Ovarian Growing Teratoma Syndrome by Rebecca M. Rentea, Aaron Varghese, Atif Ahmed, Alexander Kats, Michelle Manalang, Tazim Dowlut-McElroy, Richard J. Hendrickson

“…Ovarian immature teratoma is a germ cell tumor that comprises less than 1% of ovarian cancers and is treated with surgical debulking and chemotherapy depending on stage. …”
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Identification of Potential Selective PAK4 Inhibitors Through Shape and Protein Conformation Ensemble Screening and Electrostatic-Surface-Matching Optimization by Xiaoxuan Zhang, Meile Zhang, Yihao Li, Ping Deng

“…P21-activated kinase 4 (PAK4) plays a crucial role in the proliferation and metastasis of various cancers. However, developing selective PAK4 inhibitors remains challenging due to the high homology within the PAK family. …”
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SOCS1, a Negative Regulator of Cytokine Signals and TLR Responses, in Human Liver Diseases by Minoru Fujimoto, Tetsuji Naka

“…The studies using SOCS1-deficient mice revealed that endogenous SOCS1 is critical for the prevention of liver diseases such as hepatitis, cirrhosis, and cancers. Recent studies on humans suggest that SOCS1 is involved in the development of various liver disorders in humans. …”
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Krait2: a versatile software for microsatellite investigation, visualization and marker development by Lianming Du, Jiahao Chen, Dalin Sun, Kelei Zhao, Qianglin Zeng, Nan Yang

“…Microsatellite expansions play pivotal roles in gene expression regulation and are implicated in various neurological diseases and cancers. Although much effort has been devoted to developing efficient tools for microsatellite identification, there is still a lack of a powerful tool for large-scale microsatellite analysis. …”
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