Chimeric antigen receptor with novel intracellular modules improves antitumor performance of T cells by Pengju Wang, Yiyi Wang, Xiaojuan Zhao, Rui Zheng, Yiting Zhang, Ruotong Meng, Hao Dong, Sixin Liang, Xinyi He, Yang Song, Haichuan Su, Bo Yan, An-Gang Yang, Lintao Jia

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Multiple large language models versus experienced physicians in diagnosing challenging cases with gastrointestinal symptoms by Xintian Yang, Tongxin Li, Han Wang, Rongchun Zhang, Zhi Ni, Na Liu, Huihong Zhai, Jianghai Zhao, Fandong Meng, Zhongyin Zhou, Shanhong Tang, Limei Wang, Xiangping Wang, Hui Luo, Gui Ren, Linhui Zhang, Xiaoyu Kang, Jun Wang, Ning Bo, Xiaoning Yang, Weijie Xue, Xiaoyin Zhang, Ning Chen, Rui Guo, Baiwen Li, Yajun Li, Yaling Liu, Tiantian Zhang, Shuhui Liang, Yong Lv, Yongzhan Nie, Daiming Fan, Lina Zhao, Yanglin Pan

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DHX37 Impacts Prognosis of Hepatocellular Carcinoma and Lung Adenocarcinoma through Immune Infiltration by Yanni Xu, Qiongchao Jiang, Hejun Liu, Xiaoyun Xiao, Dinghong Yang, Phei Er Saw, Baoming Luo

“…Recently, RNA helicases have been considered potential targets in cancers. So far, there has been no detailed investigation of the biological functions of RNA helicase DHX37 in cancers. …”
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Application of large language models in disease diagnosis and treatment by Xintian Yang, Tongxin Li, Qin Su, Yaling Liu, Chenxi Kang, Yong Lyu, Lina Zhao, Yongzhan Nie, Yanglin Pan, Yuanyuan Ji

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Site Specific Effect of Tobacco Addiction in Upper Aerodigestive Tract Tumors: A Retrospective Clinicopathological Study by Ashok Kumar, Amita Sharma, Babita Ahlawat, Sonam Sharma

“…Among only smokers, 69.2% cases were of laryngeal and oro- and hypopharynx as compared to 11.5% of oral cavity cancers (nearly 6 times). Tobacco (smokeless) chewing is associated with oral cancers whereas tobacco smoking is associated with laryngeal and hypopharyngeal carcinoma. …”
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Clinicopathological features of Lynch syndrome pedigrees with MSH2 c.351G>A gene variant by Shuai Zhang, Guanyu Fu, Gongping Sun, Yuanxin Tang, Jin Meng, Zhigang Wang, Rongjun Su, Wei Liu, Xiaoxia Li

“…Results Nine patients with 19 primary cancers were found in this family, with a wide spectrum of synchronous and metachronous cancers, including digestive, reproductive, respiratory, urinary, and other systems. …”
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Establishment and internal validation of a model to predict the efficacy of Adalimumab in Crohn’s disease by Fang Wang, He Zhou, Yujie Zhang, Yu Da, Tiantian Zhang, Yanting Shi, Tong Wu, Jie Liang

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Response of Immunotherapy to Tumour-TICLs Interactions: A Travelling Wave Analysis by Joseph Malinzi, Precious Sibanda, Hermane Mambili-Mamboundou

“…There are several cancers for which effective treatment has not yet been identified. …”
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Reporting and representation of participant race and ethnicity in phase III clinical trials for solid tumors by Tianyi Wang, Dinorah J Villanueva, Ambily Banerjee, Dina Gifkins

“…Compared with SEER data, the percentages were lower for Asian/Pacific Islander across all cancers, Black/African American in breast and prostate cancers, American Indian or Alaska Native in colorectal, breast, and prostate cancers in US solely trials.Conclusions Reporting and enrollment of racial and ethnic minorities in trials remain inadequate but improving. …”
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A Rare Cause of Testicular Metastasis: Upper Tract Urothelial Carcinoma by Alper Nesip Manav, Ercan Kazan, Mehmet Şirin Ertek, Akın Soner Amasyalı, Nil Çulhacı, Haluk Erol

“…Metastatic testicular cancers are rare. Primary tumor sources are prostate, lung, and gastrointestinal tract for metastatic testicular cancers. …”
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Does Onsite Cytotechnology Evaluation Improve the Accuracy of Endoscopic Ultrasound-Guided Fine-Needle Aspiration Biopsy? by Fahad Alsohaibani, Safwat Girgis, Gurpal Singh Sandha

“…BACKGROUND: Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) is the preferred modality for the cytological diagnosis of various cancers. Onsite cytopathology interpretation is not available in most centres.…”
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ORIGINAL RESEARCH by Ciprian Camil Mireştean, Anda Crişan, Liliana Eleonora Semenescu, Adina Mitrea, Florinel Bădulescu

“…The evolution of the neutrophil-lymphocyte ratio (NLR) and the platelet-lymphocyte ratio during polychemotherapy in head and neck cancers Imaging of pericardial compressive syndromes – cardiac tamponade in oncologic patients…”
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A Study On The Histopathological Analysis Of Nasal Masses Among Patients Attending The Ent Department Of Pakistan Institute Of Medical Sciences, Islamabad by Malik Jawad Faisal, Muhammad Arshad, Moniba Zafar, Ahmed Hasan Ashfaq, Syed Fahd Shah

“…Results: The most numerous groups of changes were non-cancerous nasal growth; 55 cases (68.25%), then 25 cases (32.25%) of nasal tumours, 16 benign, and 9 malignant cases in cancerous tumours. …”
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Total Pancreatectomy for Ampullary Adenocarcinoma in a 74-Year-Old Patient: Case Report and Literature Review by Gabriela A. Arroyo Murillo, Eleonore Choppin De Janvry, Manuela Garofalo, Fatima Della Pietra

“…It represents <0.5% of all gastrointestinal cancers and approximately 7% of all periampullary cancers. …”
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BRCA2 Heterozygosity Delays Cytokinesis in Primary Human Fibroblasts by Asta Björk Jonsdottir, Maaike P. G. Vreeswijk, Ron Wolterbeek, Peter Devilee, Hans J. Tanke, Jorunn E. Eyfjörd, Karoly Szuhai

“…Background: Inherited mutations in the tumour suppressor gene BRCA2 greatly increase the risk of developing breast, ovarian and other types of cancers. So far, most studies have focused on the role of BRCA-pathways in the maintenance of genomic stability.…”
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Gastric Outlet Obstruction as the Initial Presentation of Upper Tract Urothelial Carcinoma by Karl Andersen, Sarah Burroughs, Assad Munis, Ryan T. Hoff, Alan Shapiro

“…The most common neoplasms associated with GOO include gastric, pancreatic, and biliary tract cancers. Urinary tract urothelial carcinoma has been a rarely documented cause of GOO.…”
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Blockchain-enabled digital twin system for brain stroke prediction by Venkatesh Upadrista, Sajid Nazir, Huaglory Tianfield

“…However, their application in predicting serious conditions such as heart attacks, brain strokes and cancers remains under investigation, with current research showing limited accuracy in such predictions. …”
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Disseminated Intravascular Coagulation and Malignancy: A Case Report and Literature Review by Sumit Sohal, Akhilesh Thakur, Aleena Zia, Mina Sous, Daniela Trelles

“…Disseminated Intravascular Coagulation (DIC) is a disorder of coagulation which is commonly seen as a complication of infections, traumas, obstetric diseases, and cancers especially hematological and rarely solid cancers. …”
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Patterns of Use of Flexible Sigmidoscopy, Colonoscopy and Gastroscopy: A Population-Based Study in a Canadian Province by Robert J Hilsden

“…Pressure on endoscopy resources is expected due to increased screening for GI cancers. The present study examined patterns of use of GI endoscopy in a Canadian province, Alberta, with universal health care insurance.…”
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Body Mass Index Is Associated with Hypercholesterolemia following Thyroid Hormone Withdrawal in Thyroidectomized Patients by Dong Yeob Shin, Kwang Joon Kim, Yongin Cho, Kyeong Hye Park, Sena Hwang, Woong Youn Chung, Eun Jig Lee

“…Thyroid hormone withdrawal (THW) for postoperative radioiodine adjuvant therapy or diagnostic radioiodine whole body scan in patients with differentiated thyroid cancers results in acute thyroid hormone deficiency and abnormal lipid profiles. …”
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