Lung adenocarcinoma metastasis within a pituitary neuroendocrine tumor: a case report with review of literature by Koji Suzuki, Shigeyuki Tahara, Yujiro Hattori, Shinichiro Teramoto, Eitaro Ishisaka, Chie Inomoto, Robert Yoshiyuki Osamura, Akio Morita, Yasuo Murai

“…A 75-year-old man who underwent tumor resection 36 and 18 years prior to presentation for bladder and colon cancer, respectively, without recurrence presented with bitemporal hemianopsia, ptosis, and diplopia of the right eye. …”
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Synchronous Occurrence of Splenic Pleomorphic Mantle Cell Lymphoma and Esophageal Adenocarcinoma with Overexpression of BCL1 Protein by Dominik Dabrowski, Roberto F. Silva, Michael Constantinescu, Rodney E. Shackelford, Nestor Dela Cruz, Eric X. Wei

“…Furthermore, he was lost to follow-up for a year and only received treatment after his third cancer was diagnosed. We have reviewed previous reports of synchronic mantle cell lymphoma and other solid tumors or hematological malignancies in the literature.…”
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Overexpression of IL-6 and STAT3 may provide new insights into ovine pulmonary adenocarcinoma development by Corina Toma, Roxana Popa, Lidia Ciobanu, Ioana Baldea, Irina Amorim, Diana Bochynska, Alan Wolfe, Andrada Negoescu, Claudiu Gal, Marian Taulescu

“…Abstract Background Ovine pulmonary adenocarcinoma (OPA) is caused by Jaagsiekte sheep retrovirus (JSRV) and is considered an important potential animal model for human lung cancer. The precise mechanisms of OPA oncogenesis are still uncertain. …”
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Mortality Predictive Value of APACHE II and SOFA Scores in COVID-19 Patients in the Intensive Care Unit by Mohammad Taghi Beigmohammadi, Laya Amoozadeh, Forough Rezaei Motlagh, Mojgan Rahimi, Maziar Maghsoudloo, Behzad Jafarnejad, Babak Eslami, Mohammad Reza Salehi, Kazem Zendehdel

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Daily versus three-times-weekly azithromycin in Chinese patients with non-cystic fibrosis bronchiectasis: protocol for a prospective, open-label and randomised controlled trial by Jing Li, Fei Chen, Wei Xiao, Feng Li, Lan Chen, Ting He, Yanxiong Mao, Aiping Zou, Bo Fan, Weihao Ni, Huimin You, Wenjiang Fu

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Development and validation of a prediction model for all-cause mortality in maintenance dialysis patients: a multicenter retrospective cohort study by Jingcan Wu, Xuehong Li, Hong Zhang, Lin Lin, Man Li, Gangyi Chen, Cheng Wang

“…The discrimination and accuracy of the prediction model were assessed using C-indexes and calibration curves, while the clinical value was assessed by decision curve analysis (DCA).Results The best predictors of 1-, 3-, and 5-year all-cause mortality contained nine independent factors, including age, body mass index (BMI), diabetes mellitus (DM), cardiovascular disease (CVD), cancer, urine volume, hemoglobin (HGB), albumin (ALB), and pleural effusion (PE). …”
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Trace metals potential human health risks assessment through consuming common food spices in Ado Ekiti, Southwest, Nigeria by J.A. Olusola, O.B. Akintan, O. Osanyinlusi

“…The assessment involved various methods such as Estimation of Daily Intake (EDI), Hazard Quotient (THQ), Total Hazard Quotient (TTHQ), and Cancer Risk (CR). Results: The results indicated that iron (Fe) levels varied from 0.62 mg/kg in dry onion to 210.40 mg/kg in turmeric, with an average concentration of 45.09±59.83 mg/kg. …”
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Demographic Correlates of Infant Feeding Practices and Growth Performance in the First Year of Life by Leila M. Shinn, Christy C. Tangney, Caitlyn Busche, Christine M. Sharp, Mary C. Mullen

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Engineered ipilimumab variants that bind human and mouse CTLA-4 by Brett Robison, SJ Diong, Anusha Kumar, Thomas M. Moon, Olin Chang, Bryant Chau, Christine Bee, Ishita Barman, Arvind Rajpal, Alan J. Korman, Sean West, Pavel Strop, Peter S. Lee

“…The antibody 9D9, which binds mouse CTLA-4, is a commonly used surrogate for CTLA-4 checkpoint blockade studies in mouse cancer models. In this work, we reveal that 9D9 has significant biophysical dissimilarities to therapeutic CTLA-4 antibodies. …”
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Diagnostic cholangioscopy for surgical planning of extrahepatic cholangiocarcinoma by Min Je Sung, Suk Pyo Shin, Chang-Il Kwon, Incheon Kang, Sung Hwan Lee, Seok Jeong Yang, Beodeul Kang, Hong Jae Chon, Gwangil Kim, Chansik An, Kwang Hyun Ko

“…Abstract The recent clinical outcomes of multi-regimen chemotherapy included prolonged survival and a high rate of conversion to surgery in Asian patients with advanced biliary tract cancer. The ability of single-operator cholangioscopy (SOC) to detect and stage extrahepatic cholangiocarcinoma (CCC) in intraductal lesions is becoming more important in determining the extent of surgery. …”
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Preferential Expression of B7-H6 in Glioma Stem-Like Cells Enhances Tumor Cell Proliferation via the c-Myc/RNMT Axis by Hanqing Chen, Yundi Guo, Jing Sun, Jun Dong, Qinghua Bao, Xueguang Zhang, Fengqing Fu

“…B7 homologue 6 (B7-H6), a newly identified member of the B7 costimulatory molecule family, is not only a crucial regulator of NK cell-mediated immune responses through binding to NKp30 but also has clinical implications due to its abnormal expression in human cancers. Here, we show that B7-H6 expression is abnormally upregulated in glioma tissue and that B7-H6 is coexpressed with stem cell marker Sox2. …”
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Association between transarterial chemoembolization refractoriness and prognosis in Chinese patients with hepatocellular carcinoma: a large retrospective cohort study by Qinxue Sun, Ziliang Wu, Xi Yin, Feng Li, Ri Liu

“…The Chinese College of Interventionalists (CCI) proposed a tailored definition, but its impact on HCC prognosis is still limited.MethodsThis study included 844 patients with Barcelona Clinic Liver Cancer (BCLC) stage B HCC from a multicenter dataset. …”
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Toxicity and Safety Evaluation of Doxorubicin-Loaded Cockleshell-Derived Calcium Carbonate Nanoparticle in Dogs by Abubakar Danmaigoro, Gayathri Thevi Selvarajah, Mohd Hezmee Mohd Noor, Rozi Mahmud, Md Zuki Abu Bakar

“…This finding offers opportunity to dogs with cancer that might require long-term administration of DOX without adverse effects.…”
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Current Trends in Mortality Attributable to Racial or Ethnic Disparities in Post-Surgical Population in The United States: A Population-Based Study by Christian Mpody, MD, PhD, MPH, MBA, Ana F. Best, PhD, Clara N. Lee, MD, MPP, David L. Stahl, MD, Vidya T. Raman, MD, MBA, Richard D. Urman, MD, MBA, Joseph D. Tobias, MD, Olubukola O. Nafiu, MD, FRCA, MS

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METHODS OF EVALUATION OF THE FUNCTIONAL STATUS OF THE LIVER IN THE PLANNING OF ANATOMICAL RESECTIONS ABOUT PRIMARY AND METASTATIC TUMORS: CURRENT STATE OF THE PROBLEM, THEIR OWN EX... by D. V. Sidorov, N. A. Rubtsova, A. V. Leontyev, M. V. Lozhkin, L. O. Petrov, T. N. Lazutina, I. V. Pylova, P. A. Korolev, A. G. Isaeva

“…Methacetin breath test and 99mTc-technephyt hepatobiliary scintigraphy were performed prior to major resection in 53 high-risk patients, including 48 patients with hepatic metastases from colorectal cancer and 5 patients with hepatocellular carcinoma . …”
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Strategies for H-score Normalization of Preanalytical Technical Variables with Potential Utility to Immunohistochemical-Based Biomarker Quantitation in Therapeutic Reponse Diagnost... by William E. Pierceall, Michele Wolfe, Jessica Suschak, Hua Chang, Yan Chen, Kam M. Sprott, Jeffery L. Kutok, Stella Quan, David T. Weaver, Brian E. Ward

“…In this study, we present data on two candidate calibrator nuclear-localized proteins, SNRPA and SnRNP70, with robust and consistent expression levels across breast cancers. Quantitative expression measurement of these two candidate biomarkers may potentially be used to eliminate the effect of differences in preanalytic processing of specimens by normalizing H-scores derived from test biomarkers of interest. …”
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Ethnopharmocology, phytochemistry and pharmacology of the genus Orthosiphon: A review by Rui Wang, Ling Qiu, Qing-wen Zhang, Ligen Lin

“…Previous reports have demonstrated the diverse pharmacological properties of extracts and constituents derived from Orthosiphon, such as anti-cancer, anti-diabetic, anti-inflammatory, antioxidant, hepatoprotective, analgesic, and nephroprotective effects. …”
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Insight into Nigeria’s progress towards the universal coverage of reproductive, maternal, newborn and child health services: a secondary data analysis by Xiaohui Wang, Joy James Mafiana, Xiping Shen, Wenping Hu

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Cannabidiol Ameliorates Doxorubicin-Induced Myocardial Injury via Activating Hippo Pathway by Dong T, Li J, Liang X, Wang W, Chen M, Yang G, Wu D

“…Tianwei Dong,1 Jinlian Li,2 Xinfang Liang,3 Wang Wang,3 Meichi Chen,4 Guangyuan Yang,5 Dongmei Wu4 1Key Laboratory of Microecology-Immune Regulatory Network and Related Diseases, School of Basic Medicine, Jiamusi University, Jiamusi, Heilongjiang, 154000, People’s Republic of China; 2College of Pharmacy, Jiamusi University, Jiamusi, Heilongjiang, 154007, People’s Republic of China; 3Department of Cardiology, The First Affiliated Hospital of Jiamusi University, Jiamusi, Heilongjiang, 154002, People’s Republic of China; 4School of Basic Medicine, Jiamusi University, Jiamusi, Heilongjiang, 154000, People’s Republic of China; 5Cardiovascular Medicine, The First Affiliated Hospital of Jiamusi University, Jiamusi, Heilongjiang, 154002, People’s Republic of ChinaCorrespondence: Dongmei Wu; Guangyuan Yang, Email dmwu@jmsu.edu.cn; Ygy665@126.comBackground: Doxorubicin (DOX) is a chemotherapeutic agent widely used for cancer treatment and has non-negligible cardiotoxicity. …”
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Utilizing vaginal natural orifice to facilitate bowel manipulation during totally intracorporeal ileal conduit construction: a retrospective cohort study by Kaipeng Jia, Shiwang Huang, Zhun Wang, Yuda Lin, Yiduo Bai, Chong Shen, Zhe Zhang, Zhouliang Wu, Yunkai Qie, Hailong Hu

“…Objective To explore the feasibility and efficacy of the modified technique of totally intracorporeal ileal conduit (IC) construction via vaginal approach following robot-assisted radical cystectomy (RARC) in females.Methods By comparing the perioperative outcomes of the modified technique with extracorporeal urinary diversion (ECUD), 31 females treated for bladder cancer with RARC and IC from May 2020 to December 2023 were retrospectively analyzed and divided into two groups: the ECUD group (10 patients) and the modified intracorporeal urinary diversion (MICUD group) (21 patients). …”
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