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11681
Assessment of antenatal care quality in Ethiopia: Facility-based study using service provision assessment data.
Published 2025-01-01“…Blood pressure measurement was the most commonly performed ANC component, at 79.5%, and breast examination for cancer screening was the most neglected component of ANC, at 3.3%. …”
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11682
Classification of Nanomaterial Drug Delivery Systems for Inflammatory Bowel Disease
Published 2025-02-01“…Patients with IBD frequently experience recurrent abdominal pain and bloody diarrhea, while severe cases may result in intestinal obstruction, perforation, and cancer. Lifelong maintenance therapy may thus be needed to manage these symptoms; however, traditional IBD drugs, such as 5-aminosalicylic acid, glucocorticoids, immunosuppressants, and biological agents, are often associated with problems including poor solubility, instability, and ineffective targeting, as well as causing serious side effects in non-target tissues. …”
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11683
Exploring the prevalence of gout among underrepresented low socioeconomic status type 2 diabetes populations
Published 2025-01-01“…Exclusion criteria were a personal history of cancer, organ transplantation, or current pregnancy. …”
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11684
Disulfidptosis-related gene SLC3A2: a novel prognostic biomarker in nasopharyngeal carcinoma and head and neck squamous cell carcinoma
Published 2025-01-01“…Several studies in recent years have extensively investigated the function of the disulfidoptosis-related SLC7A11 gene in cancer, but the role of its partner protein, SLC3A2, remains unknown unclear in NPC.MethodsGEO database analysis confirmed SLC3A2's prognostic impact on nasopharyngeal carcinoma. …”
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11685
Argonaute2 modulates megakaryocyte development and sex-specific control of platelet protein expression and reactivity
Published 2025-01-01“…Female Ago2-deleted platelets selectively showed downregulation of a protein cohort established in breast cancer cells to be transcriptionally regulated by estrogen receptor-beta coupled to Ago2, whereas male Ago2-deleted platelets did not. …”
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11686
Nanoparticle accumulation and penetration in 3D tumor models: the effect of size, shape, and surface charge
Published 2025-01-01“…Preclinical studies have demonstrated that nanoparticles (NPs) hold significant potential for advancing cancer therapy by enhancing therapeutic efficacy while reducing side effects. …”
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11687
BTEX Exposure Assessment and Inhalation Health Risks to Traffic Policemen in the Klang Valley Region, Malaysia
Published 2020-06-01“…A probabilistic method based on Monte Carlo simulation was applied to determine the cancer risk (CR) and hazard quotient (HQ), and a sensitivity analysis was performed to identify the greatest contributors to the estimated risks. …”
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11688
Characterizing Industrial VOC Hotspots in One of Eastern China’s Largest Petrochemical Parks Using Mobile PTR–ToF–MS Measurements
Published 2025-01-01“…The overall OH reactivity, aerosol formation potential, and lifetime cancer risk of the industrial zone were also substantially higher than those in the background zone. …”
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11689
Exosomal miR-21-5p from glioma associated mesenchymal stem cells promotes the progression and glycolysis of glioblastoma via PDHA1
Published 2025-01-01“…Pyruvate dehydrogenase A1 (PDHA1) is a key component in both the tricarboxylic acid cycle and glycolysis, playing an important role in the metabolic processes related to cancer, but its role in GBM remains unclear. Glioma associated mesenchymal stem cells (GaMSC) play a significant role in the development of glioma. …”
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11690
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11691
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11692
Tumor Microenvironment‐Responsive Nanoparticles Enhance IDO1 Blockade Immunotherapy by Remodeling Metabolic Immunosuppression
Published 2025-02-01“…Mechanistically, HMP1G NPs downregulated tumor cell‐derived IDO1 via the aryl hydrocarbon receptor/signal transducer and activator of transcription 3/interleukin signaling axis to improve kynurenine/tryptophan metabolism and immunosuppression. In a murine breast cancer model, treatment with HMP1G NPs elicited effective antitumor immunity and enhanced survival outcomes. …”
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11693
Consumo alimentar de pacientes oncológicos: onde estão as inadequações?
Published 2024-12-01“…Introdução: Os hábitos alimentares podem influenciar diretamente no estado de saúde do indivíduo, e modulam o risco para doenças crônicas não transmissíveis, como o câncer. Objetivo: Avaliar a qualidade da dieta de indivíduos em tratamento oncológico. …”
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11694
Population- and Gender-Based Investigation for Prevalence of Helicobacter pylori in Dhamar, Yemen
Published 2023-01-01“…Among 35 species of genus Helicobacter, H. pylori is the most common causative agent of human gastritis, peptic ulcer, and gastric cancer. The infection can spread through direct human-to-human contact, fecal–oral route, and contaminated water. …”
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11695
Gliomas Difusos do Adulto: Prevalência da Mutação IDH1 em um Hospital Universitário
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11696
Beneficial Effects of <i>In Vitro</i> Reconstructed Human Gut Microbiota by Ginseng Extract Fermentation on Intestinal Cell Lines
Published 2025-01-01“…Among the natural compounds that we can introduce by the diet, <i>Panax ginseng</i> extract is one of the most utilized since it contains a vast number of bioactive molecules such as phenolic acids, flavonoids, and polysaccharides that have been shown to possess antioxidant, anti-ageing, anti-cancer, and immunomodulatory activity. In this work, the ability of a <i>P. ginseng</i> extract in combination with a probiotic formulation was taken into consideration to evaluate its effects on the modulation of <i>in vitro</i> reconstructed human gut microbiota (HGM). …”
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11697
TLR7/8/9 agonists and low-dose cisplatin synergistically promotes tertiary lymphatic structure formation and antitumor immunity
Published 2025-01-01“…Abstract In situ vaccination (ISV) triggers antitumor immune responses using the patient’s own cancer antigens, yet limited neoantigen release hampers its efficacy. …”
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11698
Evaluation of maSSS/maSES-PEG2-RM26 for their potential therapeutic use after labeling with Re-188. Could their [99mTc]Tc-labeled counterparts be used to estimate dosimetry?
Published 2025-01-01“…Abstract Background Gastrin releasing peptide receptor (GRPR)-directed radiopharmaceuticals for targeted radionuclide therapy may be a very promising addition in prostate and breast cancer patient management. Aiming to provide a GRPR-targeting theranostic pair, we have utilized the Tc-99m/Re-188 radiometal pair, in combination with two bombesin based antagonists, maSSS-PEG2-RM26 and maSES-PEG2-RM26. …”
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11699
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11700
Effects of genetic ablation and pharmacological inhibition of HuR on gene expression, iron metabolism, and hormone levels
Published 2025-01-01“…Elevated HuR levels are associated with multiple disorders, including cancer and neurodegenerative diseases. Despite the identification of small molecule inhibitors targeting HuR, their detailed characterization remains limited. …”
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