Network analyses of brain tumor multiomic data reveal pharmacological opportunities to alter cell state transitions by Brandon Bumbaca, Jonah R. Huggins, Marc R. Birtwistle, James M. Gallo

“…Abstract Glioblastoma Multiforme (GBM) remains a particularly difficult cancer to treat, and survival outcomes remain poor. …”
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A phase I study of the CDK4/6 inhibitor ribociclib combined with gemcitabine in patients with advanced solid tumors by Aurora Norman, Mahesh Seetharam, Jacob Allred, Jianping Kong, Mateusz Opyrchal, Wen Wee Ma, Yanyan Lou, Grace K. Dy, Amit Mahipal, S. John Weroha, Andrea E. Wahner Hendrickson, Joel M. Reid, Alex A. Adjei

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Evaluation of Mast Cells in Oral Potentially Malignant Disorders and Oral Squamous Cell Carcinoma by Ashish Shrestha, Shashi Keshwar, Toniya Raut

“…Proper quantification of mast cells using specific stains can guide to define prognosis in oral potentially malignant disorders and oral cancer.…”
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Comparison of Antioxidant and Alpha-Glucosidase Inhibitory Properties of Moringa peregrina and Ferulago carduchorum Leaf Extracts and Microencapsulation of Superior Plant by Shiva Nouri, Maryam Moslehishad, Seyede Marzieh Hosseini, Mina Etemadi

“…Today, medicinal plants have a crucial role in treating diseases such as diabetes and cancer. These plants do not impose any side effects owing to their bioactive compounds in comparison with chemical drugs. …”
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Mixoid Liposarcoma by Azamris Azamris, Peri Handayani, Muhammad Rifki

“…Liposarcoma is malignant tumor or cancer at fatty tissue, characterized by abortif differentiated cells to lipocyte and the common type of soft tissue sarcoma, appearing slowly, enlarged, painless, nonulceratif mass submucosal at the middle age. …”
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Laminin-5 γ2 Chain Expression Correlates with Unfavorable Prognosis in Colon Carcinomas by C. Lenander, J. K. Habermann, Å. Öst, B. Nilsson, H. Schimmelpenning, K. Tryggvason, G. Auer

“…The results indicate that laminin-5 γ2 chain expression is up-regulated during the progression of human colon cancer and that it plays a role in the aggressiveness of these tumors. …”
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Cytotoxic and Antioxidant Effects of Antimalarial Herbal Mixtures by Isaac Dadzie, Shaibu Adams Avorgbedo, Regina Appiah-Opong, Obed Cudjoe

“…On the other hand, these mixtures may have anticancer potential activity characterized by cytotoxicity to cancer cells. The aim of the study was to determine the cytotoxic and antioxidant effects of five different antimalarial herbal mixtures. …”
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Dynamic Challenges of Active Tuberculosis: Prevalence and Risk Factors of Co-Infection in Clinical and Microbiological Characteristics at King Abdulaziz University Hospital, Jeddah... by Mokhtar JA, Attallah DM, Jiman-Fatani AA, Al-Rabia MW, Alqarni MA, Saleh BH, Amboon MM, Altorki TA, Alkuwaity KK, Abujamel T, Kaki R, Albarakati TN, Daghistani H, Ismail MA, Alharbi O, Abu ITM, Alfadil A, Ibrahem K, Mufrrih M, Sait AM

“…Patients undergoing hemodialysis, and those with respiratory comorbidities, cancer, diabetes, and smoking were found to have a higher mortality hazard, indicating these as significant risk factors for TB.Conclusion: This study highlights TB’s prevalence and drug resistance at KAUH, emphasizing high-risk groups, including males and young adults. …”
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Comparative evaluation of multimarker algorithms for early-stage HCC detection in multicenter prospective studies by Jinlin Hou, Thomas Berg, Arndt Vogel, Teerha Piratvisuth, Jörg Trojan, Enrico N. De Toni, Masatoshi Kudo, Katarina Malinowsky, Peter Findeisen, Johannes Kolja Hegel, Wenzel Schöning, Kairat Madin, Konstantin Kroeniger, Henry Lik-Yuen Chan, Ashish Sharma

“…Results: In STOP-HCC-ARP (algorithm development cohort), 1,006 patients {297 HCC (41.4% early-stage [Barcelona Clinic Liver Cancer {BCLC} 0/A) and 709 CLD} were included. Area under the curve (AUCs) for discriminating between early-stage HCC vs. …”
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Effect of Interleukin-17 in the Activation of Monocyte Subsets in Patients with ST-Segment Elevation Myocardial Infarction by Montserrat Guadalupe Garza-Reyes, Mónica Daniela Mora-Ruíz, Luis Chávez-Sánchez, Alejandra Madrid-Miller, Alberto Jose Cabrera-Quintero, José Luis Maravillas-Montero, Alejandro Zentella-Dehesa, Luis Moreno-Ruíz, Selene Pastor-Salgado, Erick Ramírez-Arias, Nataly Pérez-Velázquez, Adriana Karina Chávez-Rueda, Francisco Blanco-Favela, Wendy Guadalupe Vazquez-Gonzalez, Alicia Contreras-Rodríguez

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Protocol for Home-Based Solution for Remote Atrial Fibrillation Screening to Prevent Recurrence Stroke (HUA-TUO AF Trial): a randomised controlled trial by Jing Tan, Yan Liang, Yong Liu, Wei Jiang, Duo Huang, Ning Tan, Chung-Wah Siu, Jo Jo Hai, Xiaoyu Huang, Jianfeng Ye, Ji-yan Chen, Chun Ka Wong, Mi Zhou, Li-Xue Yin, Ming-Liang Zuo, Kui Kai Lau, Zhen Lei, Yingqing Feng, Bryan P Yan, Wen-Sheng Yue, Wen-Jun Zhang, Yuk-Ming Lau, Hin-Wai LUI, Koon-Ho Chan, Toi Meng Mok, Weng-Chio Tam, Kun-Chong Tam, Xiuhua Feng, Xiaofei Jiang, Guanming Tan, Mario Alberto Evora

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Reduced p63 expression is linked to unfavourable prognosis in muscle‐invasive urothelial carcinoma of the bladder by Kira Furlano, Henning Plage, Sebastian Hofbauer, Sarah Weinberger, Bernhard Ralla, Annika Fendler, Florian Roßner, Simon Schallenberg, Sefer Elezkurtaj, Martina Kluth, Maximilian Lennartz, Niclas C. Blessin, Andreas H. Marx, Henrik Samtleben, Margit Fisch, Michael Rink, Marcin Slojewski, Krystian Kaczmarek, Thorsten Ecke, Stefan Koch, Nico Adamini, Sarah Minner, Ronald Simon, Guido Sauter, Joachim Weischenfeldt, Tobias Klatte, Thorsten Schlomm, David Horst, Henrik Zecha

“…Abstract Objective There is a shortage of established prognostic biomarkers in bladder cancer. One candidate is tumour protein 63 (p63), a transcription factor of the p53 gene family that is expressed in the normal urothelium. …”
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Prognostic factors and outcomes of adjuvant and first-line metastatic treatments in melanoma a Turkish oncology group study by Nargiz Majidova, Hacı Arak, Faruk Recep Ozalp, Onur Bas, Gulhan Ozcelik Koker, Erkan Buket Ozmarasalı, Yasemin Sagdıc Karateke, Teoman Sakalar, Sendag Yaslikaya, Ilknur Deliktas Onur, Goncagul Akdag, Ali Ogul, Murad Guliyev, Elif Sahin, Ebru Engin Delipoyraz, Ali Alkan, Okan Aydın, Nurullah Ilhan, Ozkan Alan, Sinem Akbas, Yaprak Cağlar, Ali Kaan Guren, Nadiye Sever, Halil Ibrahim Ellez, Fatih Selcukbiricik, Mustafa Muhammed Atcı, Ahmet Bilici, Nebi Serkan Demirci, Tugba Basoglu, Cengiz Karacin, Ismail Oguz Kara, Bulent Yıldız, Turkkan Evrensel, Mustafa Karaca, Omer Dizdar, Elif Atag, Alpaslan Ozgun, Osman Kostek

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Long-term real-world evidence of CPX-351 of high-risk patients with AML identified high rate of negative MRD and prolonged OS by Thomas Cluzeau, Fabio Guolo, Edmond Chiche, Paola Minetto, Ramy Rahme, Sarah Bertoli, Luana Fianchi, Jean-Baptiste Micol, Michele Gottardi, Pierre Peterlin, Sara Galimberti, Xavier Thomas, Giuliana Rizzuto, Olivier Legrand, Michela Rondoni, Emmanuel Raffoux, Giambattista Bertani, Alexis Caulier, Michelina D’Argenio, Caroline Bonmati, Atto Billio, Caroline Lejeune, Barbara Scappini, Arnaud Pigneux, Patrizia Zappasodi, Christan Recher, Francesco Grimaldi, Lionel Ades, Roberto M. Lemoli

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Machine Learning Based on a Multiparametric and Multiregional Radiomics Signature Predicts Radiotherapeutic Response in Patients with Glioblastoma by Zi-Qi Pan, Shu-Jun Zhang, Xiang-Lian Wang, Yu-Xin Jiao, Jian-Jian Qiu

“…Although radiotherapy has become one of the main treatment methods for cancer, there is no noninvasive method to predict the radiotherapeutic response of individual glioblastoma (GBM) patients before surgery. …”
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In Vitro Antibacterial, Antioxidant, Cytotoxicity Activity, and In Silico Molecular Modelling of Compounds Isolated from Roots of Hydnora johannis by Teshome Degfie, Milkyas Endale, Muhdin Aliye, Rajalakshmanan Eswaramoorthy, Tariku Nefo Duke, Aman Dekebo

“…The cytotoxicity of extracts from roots of H. johannis was conducted against MCF-7 cell lines (human breast cancer) by MTT assay. According to the cytotoxicity study, n-hexane extract exhibited a high level of toxicity with 28.9 ± 5.6% cell viability. …”
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Management for Patients with De Novo or Recurrent Tumors in the Residual Kidney after Surgery for Nonfamilial Bilateral Renal Cell Carcinoma by Noboru Hara, Tsutomu Nishiyama, Norihiko Yoshimura, Satoshi Takaki, Kyoichiro Yamakado, Yasuo Kitamura, Kazuya Suzuki, Kota Takahashi

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Temporal relationship between hospital admissions for pneumonia and weather conditions in Shanghai, China: a time-series analysis by Yuan Liu, David Rogers, Yue Zhang, Haidong Kan, Weibing Wang, Jianming Xu, Renjie Chen, Xiaofang Ye, Li Peng

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Catastrophic Brain Aspergillosis after Liver Transplantation by Mohammadmahdi Abbasi, Shirin Shams Ardakani, Nasir Fakhar, Hamid Eshaghi, Hosein Alimadadi, Toktam Faghihi, Behdad Gharib, Meisam Sharifzadeh, Masoomeh Safaei

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An Incarcerated Colon Inguinal Hernia That Perforated into the Scrotum and Exhibited an Air-Fluid Level by Seisuke Ota, Toshio Noguchi, Tomoya Takao, Takumi Sakamoto, Yuichiro Kanie, Ken-ichi Omae, Shunji Fujie, Yoshiaki Kanaya, Akinori Kasahara, Tadashi Matsumra

“…He reported a history of gastric cancer that was surgically treated more than 30 years ago. …”
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