Evaluation of Podoplanin in Oral Leukoplakia and Oral Squamous Cell Carcinoma by Ashok Patil, Kishor Patil, Suyog Tupsakhare, Mahesh Gabhane, Shrikant Sonune, Shilpa Kandalgaonkar

“…Recent studies have demonstrated that podoplanin was expressed in some dysplastic lesions adjacent to primary oral cancers suggesting that podoplanin expression may occur in early oral tumorigenesis and lymphangiogenesis and therefore is related to tumor growth. …”
Get full text

Exploring Unique Extracellular Vesicles Associated Signatures: Prognostic Insights, Immune Microenvironment Dynamics, and Therapeutic Responses in Pancreatic Adenocarcinoma by Kai Nan, Ming Zhang, Zilong Geng, Yuankai Zhang, Lin Liu, Zhi Yang, Peng Xu

“…Initially, we identified differentially expressed lncRNAs (DELs) from The Cancer Genome Atlas (TCGA) and Genotype-Tissue Expression (GTEx) project datasets. …”
Get full text

Prognostic Value of Microvascular Density in Dukes A and B (T1–T4, N0, M0) Colorectal Carcinomas by Rafael Uribarrena A, Javier Ortego, Javier Fuentes, Nuria Raventós, Pilar Parra, Rafael Uribarrena E

“…Aproximatelly 30% of patients operated on for colorectal cancer (CRC), with an expectedly favourable prognosis (Dukes A-B/T1–T4, N0, M0) suffer recurrence and/or die. …”
Get full text

A clinical study of minimal blood flow clamping combined with 3D printing technology in laparoscopic nephron-sparing surgery by Lingbo Yang, Pengtao Wei, Xiaohui Li, Jiantao Sun

“…ObjectiveTo compare the safety and effectiveness of minimum flow clamping combined with 3D printing technology and highly selective renal artery clamping in laparoscopic nephron-sparing surgery.MethodsFifty-two patients with renal cancer undergoing partial resection admitted to Luoyang Central Hospital Affiliated with Zhengzhou University from 2018-01 to 2021-12 were randomly divided into two groups. …”
Get full text

The Multifaceted Role of Extracellular Vesicles in Glioblastoma: microRNA Nanocarriers for Disease Progression and Gene Therapy by Natalia Simionescu, Radu Zonda, Anca Roxana Petrovici, Adriana Georgescu

“…Glioblastoma (GB) is the most aggressive form of brain cancer in adults, characterized by poor survival rates and lack of effective therapies. …”
Get full text

Nafion®-Containing Solid Lipid Nanoparticles as a Tool for Anticancer Pt Delivery: Preliminary Studies by Maddalena Sguizzato, Elisabetta Esposito, Marcus Drechsler, Eleonora Gallerani, Riccardo Gavioli, Paolo Mariani, Federica Carducci, Rita Cortesi, Paola Bergamini

“…To evaluate the in vitro cytotoxicity, NAF were tested on human cancer cell lines K562 and A2780. No cytotoxic effect was found on both cell lines. …”
Get full text

Morphological aspects of cell-based reconstruction of rectal mucosa at surgical treatment of familial adenomatosis coli by Ye. A. Kogan, D. V. Vyshegorodtsev, N. M. Faizullina, T. A. Demura, A. M. Kuzminov, Yu. A. Shelygin, G. T. Sukhikh

“…Original method can be applied for treatment of FAC as it delays polyps and rectal cancer development for many years.…”
Get full text

A thermo-magnetohydrodynamic particle-fluid suspension moves peristaltically through a porous medium by N.M. Hafez, A.M. Abd-Alla, S.R. Mahmoud

“…In addition to managing blood flow during surgery by adjusting magnetic field intensity, the current study has biomechanical implications for cancer therapy, medication administration, and chyme motility regulation in the gastrointestinal tract.…”
Get full text

Harnessing the immunomodulatory potential of natural products in precision medicine—a comprehensive review by Maya G. Pillai, Helen Antony

“…Clinical applications of NP-based immunotherapies, such as curcumin and resveratrol in cancer treatment, highlight their diverse pharmacological properties. …”
Get full text

Risk Factors Analysis of Cutaneous Adverse Drug Reactions Caused by Targeted Therapy and Immunotherapy Drugs for Oncology and Establishment of a Prediction Model by Zimin Zhang, Mingyang Zhu, Weiwei Jiang

“…Nine risk factors were eventually identified: age, treatment modality, cancer types, history of allergies, age‐corrected Charlson comorbidity index, percentage of eosinophils, absolute number of monocytes, Eastern Cooperative Oncology Group Performance Status, and C‐reactive protein. …”
Get full text

Absorbed Dose Measurements for Teletheraphy Prediction of Superficial Dose Using Halcyon Linear Accelerator by Raymond Njinga, Adeneye Samuel, Akinyode Ajimo, Christopher Olowookere

Get full text

Risk Factors and Prevalence of Helicobacter pylori Infection in Persistent High Incidence Area of Gastric Carcinoma in Yangzhong City by Yangchun Zhu, Xiaoying Zhou, Junbei Wu, Jing Su, Guoxin Zhang

“…The aim of this study was to investigate the prevalence and risk factors of H. pylori infection in areas with high prevalence of gastric cancer in Jiangsu Province, China. Methods. A prospective epidemiologic survey of H. pylori infection was accomplished in a natural population of 5417 individuals in Yangzhong city. …”
Get full text

Engagement of the Mannose Receptor by Tumoral Mucins Activates an Immune Suppressive Phenotype in Human Tumor-Associated Macrophages by P. Allavena, M. Chieppa, G. Bianchi, G. Solinas, M. Fabbri, G. Laskarin, A. Mantovani

“…Tumor-Associated Macrophages (TAMs) are abundantly present in the stroma of solid tumors and modulate several important biological processes, such as neoangiogenesis, cancer cell proliferation and invasion, and suppression of adaptive immune responses. …”
Get full text

Enitociclib, a selective CDK9 inhibitor: in vitro and in vivo preclinical studies in multiple myeloma by Son Tran, Patrick Sipila, Melanie M. Frigault, Beatrix Stelte-Ludwig, Amy J. Johnson, Joseph Birkett, Raquel Izumi, Ahmed Hamdy, Ranjan Maity, Nizar J. Bahlis, Paola Neri, Aru Narendran

“…Abstract: Multiple myeloma (MM) is a cancer of plasma cells that remains incurable despite advances in treatment options. …”
Get full text

High Percentage of ADAM-10 Positive Melanoma Cells Correlates with Paucity of Tumor-Infiltrating Lymphocytes but Does Not Predict Prognosis in Cutaneous Melanoma Patients by Piotr Donizy, Marcin Zietek, Marek Leskiewicz, Agnieszka Halon, Rafal Matkowski

“…Decreased immunoreactivity of ADAM-10 in cancer cells from regional lymph nodes was correlated with worse prognosis; however this correlation was statistically nonsignificant (P=0.065). …”
Get full text

Spatial Distribution and Dietary Risk Assessment of Aflatoxins in Raw Milk and Dairy Feedstuff Samples from Different Climate Zones in China by Xueli Yang, Bolin Liu, Lei Zhang, Xiaodan Wang, Jian Xie, Jiang Liang

“…On average, the estimated dietary exposure to AFM1 from milk and dairy products for Chinese consumers ranged from 0.0138 to 0.0281 ng/kg bw/day, with the MOE values below 10,000, and liver cancer risk of 0.00004–0.00009 cases/100,000 persons/year. …”
Get full text

Synthesis and Cytotoxic Evaluation of Steroidal Copper (Cu (II)) Complexes by Yanmin Huang, Erbin Kong, Junyan Zhan, Shuang Chen, Chunfang Gan, Zhiping Liu, Liping Pang, Jianguo Cui

“…The results show that all steroidal copper (II) complexes display obvious antiproliferative activity against the tested cancer cells. The IC50 values of complexes 5 and 12 against Bel-7404 (human liver carcinoma) are 5.0 and 7.0 μM.…”
Get full text

Plant Sources, Extraction Methods, and Uses of Squalene by M. Azalia Lozano-Grande, Shela Gorinstein, Eduardo Espitia-Rangel, Gloria Dávila-Ortiz, Alma Leticia Martínez-Ayala

“…Scientific research has shown that SQ reduces skin damage by UV radiation, LDL levels, and cholesterol in the blood, prevents the suffering of cardiovascular diseases, and has antitumor and anticancer effects against ovarian, breast, lung, and colon cancer. The inclusion of SQ in the human diet is recommended without causing health risks; however, its intake is low due to the lack of natural sources of SQ and efficient extraction methods which limit its commercialization. …”
Get full text

Intraosseous Mucoepidermoid Carcinoma in the Mandible by George Borja de Freitas, Arthur José Barbosa de França, Stefanny Torres dos Santos, Miqueias Oliveira de Lima Júnior, Adilis Stepple da Fonte Neto, Paula Bernardon

Get full text

Leg Lengthening as a Means of Improving Ambulation Following an Internal Hemipelvectomy by Wakyo Sato, Hiroshi Okazaki, Takahiro Goto

Get full text