Multiple Group Testing Procedures for Analysis of High-Dimensional Genomic Data by Hyoseok Ko, Kipoong Kim, Hokeun Sun

“…Also, we applied all methods considered in simulation studies to identify genes associated with ovarian cancer from over 20,000 genetic sites generated from Illumina Infinium HumanMethylation27K Beadchip. …”
Get full text

To study the expression of estrogen, progesterone receptor and p53 immunohistochemistry markers in subtyping endometrial carcinoma by Anuja Yadav, Anuradha Sistla, Meenakshi Swain, Swarnalata Gowrishankar, Michelle de Padua, Tejal Modi, Rallabandi Himabindu, Neha Agarwal, Aditya Kulkarni, Trilok Bhandari, Hemanth Vudayaraju, Chinnababu, Vijay A. Reddy

“…Background: Endometrial cancer is one of the most commonly diagnosed cancers in women worldwide. …”
Get full text

Classification of Thyroid Nodules with Stacked Denoising Sparse Autoencoder by Zexin Li, Kaiji Yang, Lili Zhang, Chiju Wei, Peixuan Yang, Wencan Xu

“…The classifier performed well in discriminating malignant and benign thyroid nodules, with an area under the curve of 0.785 [0.638–0.931], accuracy of 92.9% [92.7–93.0%], sensitivity of 98.6% [95.9–101.3%], specificity of 58.3% [30.4–86.2%], positive likelihood ratio of 2.367 [1.211–4.625], and negative likelihood ratio of 0.024 [0.003–0.177]. In the cancer prevalence range of 20–40% for indeterminate thyroid nodules in cytology, the range of negative predictive value of this classifier was 37–61%, and the range of positive predictive value was 98–99%. …”
Get full text

A novel approach to earlobe reconstruction using the V to Y advancement flap by Laura Allen, Kelti Munroe, S. Mark Taylor

“…All patients had a non-melanoma skin cancer involving the earlobe. All surgeries were performed under local anesthetic at a tertiary care centre in Halifax, Canada. …”
Get full text

Identification of Key Genes and Pathways Associated with Age-Related Macular Degeneration by Junyu Zhang, Yu Zhou

“…Furthermore, several significantly enriched biological processes, including cancer, organismal injury and abnormalities, and ophthalmic disease, were identified associated with these DEGs. …”
Get full text

A Review of Caveats in Statistical Nuclear Image Analysis by Helene Schulerud, Gunner B. Kristensen, Knut Liestøl, Liljana Vlatkovic, Albrecht Reith, Fritz Albregtsen, Hàvard E. Danielsen

“…The present article discusses some of the difficulties in statistical evaluation of nuclear image analysis, and a study of cervical cancer is presented in order to illustrate the problems. …”
Get full text

Can Primary Cardiac Myxofibrosarcoma Grow Quickly from Zero to a Size Leading to Left-Sided Heart Failure within 9 Months? by Levan Karazanishvili, Eduard Limonjiani

“…The following pathologic diagnosis was finally made: myxofibrosarcoma, FNCLCC (National Federation of Cancer Centres) Grade 2. Immunohistochemistry showed positivity for Epithelial membrane antigen (EMA), desmin, calretinin, Ki67, Smooth Muscle Actin (SMA), and S100. …”
Get full text

Use of Hospital Patient and Family Advisory Councils: A Scoping Study by Barbara Lewis MBA, Chris Cochran PhD, Erika Marquez PhD, MPH, Neeraj Bhandari PhD, Jennifer Pharr PhD, Soumya Upadhyay PhD, Stowe Shoemaker PhD

“…Of the articles about specific PFACs, 70% either dealt with a condition, such as cancer, the type of person, such as youth, or both. …”
Get full text

The tyrosine kinase inhibitor lenvatinib is oxidized by rat cytochromes P450 and affects their expression in rat liver by Indra Radek, Jelínková Sandra, Kollárová Katarína, Zahumenská Petra, Dvořák Josef, Dušková Šárka, Dračínská Helena

“…Lenvatinib is an orally effective tyrosine kinase inhibitor used to treat several types of tumors, including progressive, radioiodine-refractory differentiated thyroid cancer and advanced renal cell carcinoma. Although this drug is increasingly used in therapy, its metabolism and effects on the organism are still not described in detail. …”
Get full text

Thermal performance and MHD peristaltic flow of hybrid nanofluid (Au-Ta/Blood) in an asymmetric conduit with electro-osmosis and shape factor effects by K. Thirunavukarasan, G. Sucharitha

“…The current research aims to create a mathematical model for targeted drug delivery systems, applicable in areas like cancer treatment, genetic disorder therapies, and infection management. …”
Get full text

Examining adherence to oral anticancer medications through a human factors engineering framework: Protocol for a scoping review. by Irene D Lin, Matthew B Shotts, Ahmad Al-Hader, Kellie Jones Weddle, Richard J Holden, Emily L Mueller, Monica R Macik, Mirian Ramirez, Ephrem Abebe

“…<h4>Background</h4>The number of oral anticancer medications has increased over the past few decades, opening new possibilities in cancer care and improving convenience for patients and caregivers. …”
Get full text

A model of competing saturable kinetic processes with application to thepharmacokinetics of the anticancer drug paclitaxel by Rebeccah E. Marsh, Jack A. Tuszyński, Michael Sawyer, Kenneth J. E. Vos

“…A saturable multi-compartment pharmacokinetic model for the anti-cancer drug paclitaxel is proposed based on a meta-analysis of pharmacokinetic data published over the last two decades. …”
Get full text

A case of immune checkpoint inhibitor-related conjunctivitis controlled by tacrolimus eye drops by Ayaka Kawaguchi, Hayato Tanaka, Hitoshi Tabuchi, Kei Nakai, Atsuki Fukushima

“…The patient was previously undergoing treatment for gastric cancer with nivolumab, with the final dose administered one week before the first ophthalmology visit. …”
Get full text

Prognosis of the Keratinizing Squamous Cell Carcinoma of the Tongue Based on Surveillance, Epidemiology, and End Results Database by Hai Yu, Shuping Xie, Xinkai Zheng, Qiqi Zhao, Xichun Xia, Wai-Kit Ming, Leong Nga Cheng, Xi Duan, WenHsien Ethan Huang, Fang Huang, Jun Lyu, Liehua Deng

“…The model indicated that age, radiotherapy sequence, SEER stage, marital status, tumor size, American Joint Committee on Cancer (AJCC) stage, radiotherapy status, race, lymph node dissection status, and sex were factors influencing the OS of patients with KTSCC. …”
Get full text

Metachronous Rectum Metastases from Gastric Adenocarcinoma: A Case Report by Deniz Tural, Fatih Selçukbiricik, Abdülkadir Erçalışkan, Berin İnanç, Feray Günver, Evin Büyükünal

“…Cytokeratin 7 (CK7) was found to be extensively strongly positive, Cytokeratin 20 (CK20) was negative in the immunohistochemical staining of the biopsy obtained from rectosigmoid area. Conclusion. Gastric cancer is among the frequent cancers today, most of which are adenocarcinomas. …”
Get full text

A Mechanistic Study on the Non-genotoxic Carcinogenicity of the Food Contaminant Semicarbazide by Daniel P. Fitzpatrick

“…These changes in the cellular environment could be the initiation mechanism that facilitates the manifestation of cancer in a cell population. The induced upregulation of protein kinase C activity within NRK cells by semicarbazide can be extrapolated to downstream mediators of the Ca2+ dependent signalling pathway and the mitogen activated protein kinase signalling pathway. …”
Get full text

Risk Assessment of BRONJ in Oncologic Patients Treated with Bisphosphonates: Follow-Up to 18 Months by Scilla Sparabombe, Lucia Vitali, Alessandra Nori, Ricarda Sara Berlin, Marta Mazur, Giovanna Orsini, Angelo Putignano

“…The aim of the study is to monitor the BRONJ level of risk health in patients with cancer, according to a preventive clinical protocol, which is firstly aimed at reducing risk factors such as the periodontal infections. …”
Get full text

Dual-mode-driven nanomotors targeting inflammatory macrophages for the MRI and synergistic treatment of atherosclerosis by Min Wei, Qiaoji Jiang, Shuang Bian, Pengzhao Chang, Bangbang Li, Changzhou Shi, Yangang Zhu, Yanchen Wang, Pingfu Hou, Jingjing Li

Get full text

Gastric MALT Lymphoma with Giant Ulcer from Untreated H. pylori: Role of Endoscopic Biopsy – A Case Report. by Hysni Dede, Rovena Roshi, Gentiana Cekodhima, Manjola Tahiraj, Augusto Orlandi

“…It often presents with nonspecific symptoms like dyspepsia, nausea, and epigastric pain and can mimic other gastric pathologies, such as peptic ulcers or gastric cancer. This case report is significant as it highlights the importance of thorough biopsy procedures in diagnosing gastric MALT lymphoma. …”
Get full text

Transposição da artéria gastroduodenal na reconstrução vascular de lesão invasiva do hilo hepático por metástase de adenocarcinoma colorretal: relato de caso by Lucas Lourenço de Oliveira, Iasmin Maria Rodrigues Saldanha, Yago Eloy Souza Barbosa, Renato Mazon Lima Verde Leal, Abner Moreira Sampaio, Annya Costa Araújo de Macedo Goes, Marcelo Leite Vieira Costa

“…Resumo O câncer colorretal é um dos cânceres mais prevalentes no Brasil. …”
Get full text