Association of Glycemic Indices (Hyperglycemia, Glucose Variability, and Hypoglycemia) with Oxidative Stress and Diabetic Complications by Eleftheria Papachristoforou, Vaia Lambadiari, Eirini Maratou, Konstantinos Makrilakis

“…Oxidative stress has been associated with a variety of pathologic conditions, including diabetes mellitus (DM), cancer, atherosclerosis, neurodegenerative diseases, rheumatoid arthritis, ischemia/reperfusion injury, obstructive sleep apnea, and accelerated aging. …”
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Ornamental Exterior versus Therapeutic Interior of Madagascar Periwinkle (Catharanthus roseus): The Two Faces of a Versatile Herb by Naghmeh Nejat, Alireza Valdiani, David Cahill, Yee-How Tan, Mahmood Maziah, Rambod Abiri

“…The ethnobotanical significance of MP is exemplified by its international usage as a traditional remedy for abundant ailments and not only for cancer. TIAs are present only in micro quantities in the plant and are highly poisonous per se rendering a challenge for researchers to increase yield and reduce toxicity.…”
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Calculation of Involved and Noninvolved Organs Doses in Carbon Therapy of Brain Tumor Using GEANT4 Simulation Toolkit by Maria Ahmadi, Seyed Mohammad Motevalli, Payvand Taherparvar, Vahid zanganeh

“…Notably, neutrons and photons can significantly increase energy transfer to distant organs, raising secondary cancer risk.Conclusion: The findings presented in this article demonstrated that the involvement of secondary particles in the dose received by both the brain and other organs remains minimal, as the highest absorbed dose was predominantly localized within the tumor.…”
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Textural Analysis of Nuclear Mitotic Apparatus Antigen (NuMA) Spatial Distribution in Interphase Nuclei from Human Drug-Resistant CEM Lymphoblasts by Naima Rafki‐Beljebbar, Françoise Liautaud‐Roger, Dominique Ploton, Jean Dufer

“…In tumour cell lines, the resistance of cancer cells to a variety of structurally unrelated chemotherapeutic drugs is termed multidrug‐resistance or MDR. …”
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Prognostic factors for survival in patients with advanced cholangiocarcinoma treated with percutaneous transhepatic drainage by Tomas Rohan, Barbora Cechova, Peter Matkulcik, Matej Straka, Jan Zavadil, Michal Eid, Michal Uher, Marek Dostal, Tomas Andrasina

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CD169 Expression in Lymph Nodes is Associated with Increased Infiltration of CD8+ T Cells in Tumors: A Systematic Review and Meta-Analysis by Yong Wang, Xiao-Ting Wu, Jing Chen

“…The risk of death was 55% lower for patients with high CD169 expression, and high CD169 expression may be associated with favorable survival outcomes in cancer patients. However, the number and heterogeneity of the studies should be taken into consideration when evaluating the analysis. …”
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Peptide-Based Vaccination Therapy for Rheumatic Diseases by Bin Wang, Shiju Chen, Qing Zheng, Yuan Liu, Guixiu Shi

“…Peptide-based vaccination is a highly desirable strategy in treating noninfection diseases, such as cancer and autoimmune diseases, and has gained increasing attentions. …”
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Repeated Liver Resection for Colorectal Liver Metastases: A Comparison with Primary Liver Resections concerning Perioperative and Long-Term Outcome by Kristoffer Jönsson, Gerd Gröndahl, Martin Salö, Bobby Tingstedt, Roland Andersson

“…The study aimed to evaluate differences in intraoperative blood loss and complications comparing the primary and the repeated liver resection for metastases of colorectal cancer (CRC), as well as to evaluate differences in long-time follow-up. …”
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Therapeutic Mechanism and Effect of Camptothecin on Dextran Sodium Sulfate-Induced Ulcerative Colitis in Mice by Yizhuo Wang, Kunjian Liu, Zhiyong Qi, Tong Chen, Wei Yu, Yang Jiang, Guofeng Li, Huijie Xiao

“…It possesses various antitumor activities and is mainly used in the treatment of colon, ovarian, liver, and bone cancers as well as leukemia. CPT inhibits the expressions of inflammatory genes and can prevent death from chronic inflammation. …”
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Efficacy of endoscopic vacuum therapy in esophageal luminal defects: a systematic review and meta-analysis by Ishaan Vohra, Harishankar Gopakumar, Neil R. Sharma, Srinivas R. Puli

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The Use of Noninvasive Velacur® for Discriminating between Volunteers and Patients with Chronic Liver Disease: A Feasibility Study by Michael P. Curry, Edward Tam, Caitlin Schneider, Noha Abdelgelil, Tarek Hassanien, Nezam H. Afdhal

“…Nonalcoholic fatty liver disease is the leading cause of chronic liver disease globally and can progress to cirrhosis, liver failure, and liver cancer. Current AASLD, AGA, and ADA guidelines recommend assessment for liver fibrosis in all patients with NAFLD. …”
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Arsenic Induces Continuous Inflammation and Regulates Th1/Th2/Th17/Treg Balance in Liver and Kidney In Vivo by Xiaoxu Duan, Guowei Xu, Jinlong Li, Nan Yan, Xin Li, Xuping Liu, Bing Li

“…Numerous studies on arsenic-induced hepatonephric toxicity including cancer have been reported. Given that chronic inflammatory response and immune imbalance are associated with oncogenesis, we investigated whether arsenic could influence the hepatic and nephritic expression of inflammatory factors and the differentiation of T cells. …”
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Phylostratigraphic analysis of gene networks of human diseases by Z. S. Mustafin, S. A. Lashin, Yu. G. Matushkin

“…It was also shown that among the gene networks analyzed, the highest proportion of evolutionarily young genes was found in the networks associated with diseases of the immune system (65 %), and the highest proportion of evolutionarily ancient genes was found in the networks responsible for the formation of human dependence on substances that cause addiction to chemical compounds (88 %); gene networks responsible for the development of infectious diseases caused by parasites are signif icantly enriched for evolutionarily young genes, and gene networks responsible for the development of specif ic types of cancer are signif icantly enriched for evolutionarily ancient genes.…”
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An Investigation of Electrospun Clerodendrum phlomidis Leaves Extract Infused Polycaprolactone Nanofiber for In Vitro Biological Application by Siranjeevi Ravichandran, Rajesh Jegathaprathaban, Jeyalakshmi Radhakrishnan, R. Usha, V. Vijayan, Aklilu Teklemariam

“…PCL-CPM mats exposed to oral cancer (HSC-3) and renal cell carcinoma (ACHN) cell lines displayed promising anticancer activity with less than 50% survival rate after 24 h of incubation. 2,2-Diphenyl-1-picrylhydrazyl (DPPH) assay performed on PCL-CPM nanofibers revealed the antioxidant scavenging activity with maximum inhibition of 34% suggesting the role of the secondary metabolites release from scaffold. …”
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Perception of the Importance of Inherited Genetics and Lifestyle on the Development of Chronic Diseases: A UK Cross‐Sectional Survey by Aamir Hussain, Lourdes Santos‐Merx, Mariasole Da Boit

“…Moreover, the majority of the respondents chose lifestyle over inherited genes as most important factor for cancer, cardiovascular disease and Type 2 Diabetes development (50.8% vs. 29.6%, 79% vs. 11.9%, 85.7% vs. 9.6%; respectively), while 60.6% of respondents selected inherited genes for rheumatoid arthritis (p < 0.05). …”
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The Kidney Transplant Evaluation Process in the Elderly: Reasons for Being Turned down and Opportunities to Improve Cost-Effectiveness in a Single Center by Beatrice P. Concepcion, Rachel C. Forbes, Aihua Bian, Heidi M. Schaefer

“…After adjustment for patient demographics and comorbid conditions, history of CAD, PVD, or both (OR = 1.75, 95% CI (1.20, 2.56), p=0.004), chronic obstructive pulmonary disease (OR = 8.75, 95% CI (2.81, 27.20), p=0.0002), and cancer (OR 2.59, 95% CI (1.18, 5.67), p=0.02) were associated with a higher risk of being turned down. 14.8% of patients underwent unnecessary basic testing and 9.6% underwent unnecessary supplementary testing with the charges over a 3-year period estimated at $304,337. …”
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C-reactive protein as a diagnostic marker for ovarian carcinoma by Angga Dewi Umar Wahyu, Syahrul Rauf, Susiawaty Susiawaty, Maisuri T. Chalid, Nugraha Utama Pelupessy, Irma Savitri

“… Ovarian carcinoma is a leading cause of death in gynecological cancers, making early detection crucial for improving survival rates. …”
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Melanoma Mimicking Malignant Peripheral Nerve Sheath Tumor with Spread to the Cerebellopontine Angle: Utility of Next-Generation Sequencing in Diagnosis by Katie Fox Hanson, Paul Birinyi, Ronald Walker, Constantine Raptis, Rebecca Chernock, Jeroen Coppens, Katherine E. Schwetye

“…Next-generation sequencing of a panel of cancer-associated genes demonstrated 19 identical, clinically significant mutations as well as a high tumor mutation burden in both the parotid-region and CP angle tumors, indicating a metastatic relationship between the two and a melanocytic identity of the parotid-region tumor.…”
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Free radicals and their impact on health and antioxidant defenses: a review by Nisansala Chandimali, Seon Gyeong Bak, Eun Hyun Park, Hyung-Jin Lim, Yeong-Seon Won, Eun-Kyung Kim, Sang-Ik Park, Seung Jae Lee

“…Chronic conditions such as cancer, cardiovascular diseases, neurodegenerative disorders, and inflammatory diseases have been strongly associated with the harmful effects of free radicals. …”
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Annotation-free deep learning for predicting gene mutations from whole slide images of acute myeloid leukemia by Bo-Han Wei, Xavier Cheng-Hong Tsai, Kuo-Jui Sun, Min-Yen Lo, Sheng-Yu Hung, Wen-Chien Chou, Hwei-Fang Tien, Hsin-An Hou, Chien-Yu Chen

“…Despite the demonstrated potential for characterizing gene mutations directly from WSIs in certain cancers, challenges remain due to image resolution and reliance on manual annotations for acute myeloid leukemia (AML). …”
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