Unraveling multimodality of digital health records by comparing mortality trajectories of diagnoses of diseases from over 12 million patients. by Hyojung Paik

“…For example, viral hepatitis, a known predisposing feature of liver cancer in Asia, was observed to initiate in younger Koreans. …”
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Doubling of Decipher Biopsy Genomic Score Is Related to Disease Reclassification on Subsequent Surveillance Biopsy but Not Adverse Features on Radical Prostatectomy by Kamyar Ghabili, Nathan Paulson, Jamil S. Syed, Cayce B. Nawaf, Ghazal Khajir, Darryl T. Martin, John Onofrey, Michael S. Leapman, Angelique Levi, Jeffrey C. Weinreb, Peter A. Humphrey, Preston C. Sprenkle

“…In a man on active surveillance for low-risk prostate cancer, a doubling of the Decipher biopsy score within genomic low-risk category from first to the second biopsy related to biopsy reclassification to Gleason grade group 4 on the third biopsy. …”
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A Case Report Demonstrating How the Clinical Presentation of the Diffuse Sclerosing Variant of Papillary Thyroid Carcinoma Can Mimic Benign Riedel’s Thyroiditis by Jennifer Walsh, Tomas P. Griffin, Carmel B. Ryan, James Fitzgibbon, Patrick Sheahan, Matthew S. Murphy

“…DSV-PTC is one of the more aggressive forms of thyroid cancer but with early diagnosis and appropriate treatment patients may have excellent outcomes.…”
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Misdiagnosis of Extensive Maxillofacial Infection and Its Relationship with Periodontal Problems and Hyperglycemia by Cristian Statkievicz, Leonardo P. Faverani, Pedro Henrique Silva Gomes-Ferreira, Gabriel Ramalho-Ferreira, Idelmo Rangel Garcia-Junior

“…The patient was then referred to oral oncology center by emergency physician with cancer suspicion. After 15 days, the patient returned to the same emergency room and was attended by the surgical and maxillofacial trauma team, presenting tachycardia, tachypnea, dysphagia, and trismus. …”
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KRAS Mutation in Serous Borderline Tumor of the Testis: Report of a Case and Review of the Literature by Sarah Bouri, Jean-Christophe Noël, Xavier Catteau, Walid Al Hajj Obeid, Ilyas Svistakov, Thierry Roumeguère, Nicky D’Haene, Sandrine Rorive

“…The tumor cells express cytokeratin 7 (CK7), cytokeratin 5-6 (CK5-6), cancer antigen 125 (CA125), estrogen (ER), progesterone (PR), Wilm’s tumor gene (WT1), paired box gene 8 (PAX8), Ber-EP4, and epithelial membrane antigen (EMA). …”
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Novel cis-Pt(II) Complexes with Alkylpyrazole Ligands: Synthesis, Characterization, and Unusual Mode of Anticancer Action by Jana Kasparkova, Hana Kostrhunova, Vojtech Novohradsky, Аlexey A. Logvinov, Viktor V. Temnov, Nataliya E. Borisova, Tatiana A. Podrugina, Lenka Markova, Pavel Starha, Alexey. A. Nazarov, Viktor Brabec

“…It is noteworthy that while chlorido complexes display activity in a variety of cancer cell lines comparable to cisplatin, iodido complexes are considerably more potent due to their enhanced hydrophobicity and consequently enhanced cellular accumulation. …”
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Monoclonal Antibodies for Non-Hodgkin's Lymphoma: State of the Art and Perspectives by Giulia Motta, Michele Cea, Eva Moran, Federico Carbone, Valeria Augusti, Franco Patrone, Alessio Nencioni

“…Monoclonal antibodies have been the most successful therapeutics ever brought to cancer treatment by immune technologies. The use of monoclonal antibodies in B-cell Non-Hodgkin's lymphomas (NHL) represents the greatest example of these advances, as the introduction of the anti-CD20 antibody rituximab has had a dramatic impact on how we treat this group of diseases today. …”
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Synthesis of Arginase Inhibitors: An Overview by Maria Cristina Molaro, Chiara Battisegola, Marica Erminia Schiano, Mariacristina Failla, Maria Grazia Rimoli, Loretta Lazzarato, Konstantin Chegaev, Federica Sodano

“…In recent decades, the abnormal expression of ARG-1 or ARG-2 has been reported to be increasingly linked to a variety of diseases, including cardiovascular disease, inflammatory bowel disease, Alzheimer’s disease, and cancer. Therefore, considering the current relevance of this topic and the need to address the growing demand for new and more potent ARG inhibitors in the context of various diseases, this review was conceived. …”
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The Role of Gut Microbiota in Tumor Immunotherapy by Miao Wu, Jiawei Bai, Chengtai Ma, Jie Wei, Xianjin Du

“…Some bacteria help fight tumors by activating immunity, while some bacteria mediate immunosuppression to help cancer cells escape from the immune system. More and more studies have revealed that the effects and complications of tumor immunotherapy are related to the composition of the gut microbiota. …”
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Role of the Surgical Method in Development of Postoperative Cholangiocarcinoma in Todani Type IV Bile Duct Cysts by Hong-tian Xia, Tao Yang, Bin Liang, Jian-ping Zeng, Jia-hong Dong

“…Radical resection of both intra- and extrahepatic cysts combined with hepatic resection and Roux-en-Y hepaticojejunostomy is associated with a reduced risk of subsequent cancer development. Procedures in which radical cyst excision is not performed are associated with a greater risk of subsequent malignancy.…”
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The quantitative characteristic of morphological and structural changes in the diverted regions of the large intestine by A. S. Akopyan, E. V. Manukyan, T. G. Bagdasaryan, A. F. Abramyan, A. A. Akopyan

“…Radical surgery at complicated forms of colorectal cancer frequently results in colostoma formation. …”
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Systemic inflammatory response index improves prognostic predictive value in intensive care unit patients with sepsis by Tuo Xu, Shuaiwei Song, Ke Zhu, Yin Yang, Chengyu Wu, Naixue Wang, Shu Lu

“…The systemic inflammatory response index (SIRI), a new inflammatory indicator, has shown good predictive value in chronic infection, stroke, and cancer. The purpose of this study was to investigate the connection between sepsis and SIRI and evaluate its predictive usefulness. …”
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Therapeutic Effects of Yoga in Reducing Stress in Hypertensive Patients by Evelyn Carolina Betancourt Rubio, Walter Alberto Vayas Valdiviezo, Daniela Abigail Cobo Álvarez

“…Evidence shows that stress contributes to the etiology of heart disease, cancer and stroke. <br /><strong>Objective:</strong> to evaluate the effects of yoga as a therapy in reducing stress in patients with high blood pressure. …”
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A cross-sectional survey on the effects of ambient temperature and humidity on health outcomes in individuals with chronic respiratory disease by Samantha Mekhuri, Shirley Quach, Caroline Barakat, Winnie Sun, Mika L Nonoyama

“…., asthma, sleep apnea, interstitial lung disease, lung cancer) and residing in Canada for ≥ 1 year. Negative responders to weather extremes were *a priori* defined as having a change of ≥ 2 points in the CAT…”
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Optimal Analysis Method for Dynamic Contrast-Enhanced Diffuse Optical Tomography by Michael Ghijsen, Yuting Lin, Mitchell Hsing, Orhan Nalcioglu, Gultekin Gulsen

“…Hence, implementation of a combined MRI-DOT system to image ICG enhancement can potentially be a promising tool for breast cancer imaging.…”
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Successful pancreatic pseudocyst drainage using lumen-apposing metal stent for preventing re-rupture of splenic artery pseudoaneurysm by Takashi Ito, Tsukasa Ikeura, Koh Nakamaru, Masataka Masuda, Shinji Nakayama, Makoto Naganuma

“…A 59-year-old man presented with back pain, and contrast-enhanced computed tomography (CECT) revealed pancreatic tail cancer with multiple liver metastases. After three courses of chemotherapy, CECT revealed good response with shrinkage of the tumors. …”
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Genomic landscape and comparative analysis of tissue and liquid-based NGS in Taiwanese anaplastic thyroid carcinoma by Chun-Nan Yeh, Shu-Fu Lin, Chia-Ling Wu, Miaw-Jene Liou, I-Wen Chen, Chiao-Ping Chen, Ching-Fu Chang, Qi‑An Wang, Chiao-En Wu

“…Abstract Anaplastic thyroid carcinoma (ATC) is an aggressive cancer that requirements rapid diagnosis and multimodal treatment. …”
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Unraveling relationship between the genetic polymorphism CYP2A13 and nicotine metabolism of male smokers in Medan, Indonesia by Noni Novisari Soeroso, Rozaimah Zain-Hamid, Syamsul Bihar, Chaliza Soliha, Fannie Rizki Ananda, Aida

“…CYP2A13, a key enzyme in nicotine and xenobiotic metabolism, is implicated in tobacco smoke-related lung cancer. Aim This study investigated the association between CYP2A13 genetic polymorphism and nicotine metabolism in male smokers in Medan, Indonesia. …”
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Development of a UPLC-MS/MS Method for the Quantification of VS-5584 and Its Application in Pharmacokinetic Studies in Rats by Chunling Zhou, Xiaoxin Li, Aiping He, Tianzhu Liu, Jinmiao Tian, Meihua Jiang, Lina Fang

“…VS-5584 is a small-molecular compound that showed equivalent activity against mTOR and all class I PI3K isoforms and demonstrated preclinical activity in diverse cancer cell lines and xenograft tumor model, and rational combination of VS-5584 and other target therapies achieved promising outcomes in oncology. …”
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siRNA therapeutics for effective management of rheumatoid arthritis by Vishakha R. Chakole, Tathagata Dutta, Priyankar Sen

“…This property makes siRNA a valuable tool for developing RNAi therapeutics, particularly for managing conditions like osteoporosis, cancer, genetic disorders, and autoimmune disorders. …”
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