Proteomics and Its Current Application in Biomedical Area: Concise Review by Semira Gobena, Bemrew Admassu, Mebrie Zemene Kinde, Abebe Tesfaye Gessese

“…In the biomedical field, proteomics finds widespread application in cancer research and diagnosis, stem cell studies, and the diagnosis and research of both infectious and noninfectious diseases. …”
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Proteomic Technology “Lens” for Epithelial-Mesenchymal Transition Process Identification in Oncology by Monica Neagu, Carolina Constantin, Marinela Bostan, Constantin Caruntu, Simona Rebeca Ignat, Sorina Dinescu, Marieta Costache

“…We present herein, using various proteomic technologies, the identification in cancer cell lines and in tumour tissue EMT-related proteins, proteins that are involved in the activation of different cellular pathways. …”
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Clinical Characteristics of Cutaneous Melanoma and Second Primary Malignancies in a Dutch Hospital-Based Cohort of Cutaneous Melanoma Patients by Haike M. J. van der Velden, Michelle M. van Rossum, Willeke A. M. Blokx, Jan B. M. Boezeman, Marie-Jeanne P. Gerritsen

“…In conclusion, 48 patients developed a subsequent malignancy. As nonmelanoma skin cancer is the most frequent second malignancy, our results subscribe to the necessity of follow-up by a dermatologist.…”
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Aspects of improving metrological characteristics of a sensor based on palladium nanoparticles for methionine determination by Eduard V. Gorchakov, Darya O. Perevezentseva, Elena A. Vaitulevich, Oksana V. Dubinina

“…It is also a radioprotector and can be used in cancer diagnosis. Methionine is commonly used as an amino acid supplement in poultry and cattle feed, as well as in sports nutrition and medicine. …”
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Helicobacter pylori Infection and Hepatobiliary Pathology by S. V. German, I. P. Bobrovnitsky

“…Different species of the Helicobacter genus, including H. pylori, are shown to contribute to the development of liver cancer. However, some researchers report data against the involvement of H. pylori in the pathogenesis of various hepatobiliary diseases.Conclusion.  …”
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Macrophages in Tumor Microenvironments and the Progression of Tumors by Ning-Bo Hao, Mu-Han Lü, Ya-Han Fan, Ya-Ling Cao, Zhi-Ren Zhang, Shi-Ming Yang

“…Recently, it was also found that tumor-associated macrophages interact with cancer stem cells. This interaction leads to tumorigenesis, metastasis, and drug resistance. …”
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Effect of Dietary Inclusion of Chitosan on Survival and Selected Cellular Antioxidants in <i>Drosophila melanogaster</i> by O.G. Igharo, L.I. Abadaike, J.O. Osunbor, I.C. Owie, A.I. Aruomaren, E.L. Igharo, K.I. Ikeke

“…Reduced antioxidant levels have been linked to accelerated aging and conditions leading to death like cancer. Based on the fact that antioxidant slow aging process and reduces risks of life threatening conditions. …”
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Evaluation of the genotoxic and transformation potential induced by asbestos compared to cleavage fragments by Sebastiano La Maestra, Gaia M. Militello, Stefano Alberti, Mirko Benvenuti, Laura Gaggero

“…This study used human epithelial cancer cells (A549) and a mouse fibroblast cell line (Balb/c 3T3) to compare the genotoxic and carcinogenic effects of a sample of amphibole asbestos with samples of fibrous not asbestiform named cleavage fragments (CV) obtained by grinding non-asbestiform amphiboles. …”
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Halodule uninervis extract facilitates the green synthesis of gold nanoparticles with anticancer activity by Nadine Wehbe, Joelle Edward Mesmar, Riham El Kurdi, Ali Al-Sawalmih, Adnan Badran, Digambara Patra, Elias Baydoun

“…The produced AuNPs exhibited anticancer activity against several human cancer cell lines, highlighting their potential efficacy as anticancer therapeutic agents. …”
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Mechanisms and Therapeutic Potential of GPX4 in Pain Modulation by Shiwen Fan, Kaixin Wang, Tianhao Zhang, Daling Deng, Jiwei Shen, Bowen Zhao, Daan Fu, Xiangdong Chen

“…This review systematically explores GPX4’s functions across various pain models, including neuropathic, inflammatory, low back, and cancer-related pain. Specifically, the focus includes GPX4’s physiological roles, antioxidant defense mechanisms, regulation of ferroptosis, involvement in signal transduction pathways, and metabolic regulation. …”
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Endoscopic Retroperitoneal Adrenalectomy for Adrenal Metastases by Gintaras Simutis, Givi Lengvenis, Virgilijus Beiša, Kęstutis Strupas

“…A retrospective study was conducted, and clinical data, tumor characteristics, and oncologic outcomes were acquired and analyzed. Results. Renal cancer was the primary site of malignancy in 44.4% of cases. …”
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Regulating the PI3K and AMPK pathway: the secret of 1-deoxynojirimycin's success in alleviating chronic diseases by Chengwei Yu, Qirui Hu

“…Meanwhile, DNJ has also been proved to exert anti-obesity, anti-cardiovascular diseases and anti-cancer effects. However, the underlying mechanisms are unclear yet, which hinders the applications of DNJ in clinic and food industry. …”
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Acquired Elliptocytosis as a Manifestation of Myelodysplastic Syndrome Associated with Deletion of Chromosome 20q by Sukesh Manthri, Naresh K. Vasireddy, Sindhura Bandaru, Swati Pathak

“…A 73-year-old male with a history of prostate cancer presented to the hospital for evaluation of bleeding gums. …”
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CAR T cells for treating autoimmune diseases by Dimitrios Mougiakakos, Ulrike Koehl, Stephan Fricke, Ulrich Blache, Sandy Tretbar

“…In the wake of its success in cancer therapy, adoptive transfer of engineered T cells modified with chimeric antigen receptors (CAR) for target recognition could now become a therapeutic option for some autoimmune diseases. …”
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Structure-guided identification of mitogen-activated protein kinase-1 inhibitors towards anticancer therapeutics. by Md Nayab Sulaimani, Shazia Ahmed, Farah Anjum, Taj Mohammad, Anas Shamsi, Ravins Dohare, Md Imtaiyaz Hassan

“…Hence, targeting MAPK1 can be crucial to control metastasis in cancer therapeutics. In this study, we utilized a structure-guided virtual screening approach to screen a library of thousands of natural compounds from the ZINC database. …”
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Gremlin, a Bone Morphogenetic Protein Antagonist, Is a Crucial Angiogenic Factor in Pituitary Adenoma by Kenta Koketsu, Daizo Yoshida, Kyongsong Kim, Yudo Ishii, Shigeyuki Tahara, Akira Teramoto, Akio Morita

“…Several recent reports have shown that Gremlin is also involved in angiogenesis of lung cancer and diabetic retinopathy. The purpose of this study was to investigate the role of Gremlin in tumor angiogenesis in pituitary adenoma. …”
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Transcriptome Analysis of the Thymus in Short-Term Calorie-Restricted Mice Using RNA-seq by Zehra Omeroğlu Ulu, Salih Ulu, Soner Dogan, Bilge Guvenc Tuna, Nehir Ozdemir Ozgenturk

“…Calorie restriction (CR), which is a factor that expands lifespan and an important player in immune response, is an effective protective method against cancer development. Thymus, which plays a critical role in the development of the immune system, reacts to nutrition deficiency quickly. …”
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Geographical prevalence and risk factors for pterygium: a systematic review and meta-analysis by Zhe Yuan, Lei Liu, Jingyang Wu, Desheng Huang, Jin Geng

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lncRNA ZFAS1 Promotes HMGCR mRNA Stabilization via Binding U2AF2 to Modulate Pancreatic Carcinoma Lipometabolism by Luoluo Wang, Yi Ruan, Xiang Wu, Xinhua Zhou

“…ZFAS1 expression in PC and normal counterparts retrieved from the Genotype-Tissue Expression (GTEx) project and The Cancer Genome Atlas (TCGA) database was analysed by GEPIA2. …”
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