Targeting ferroptosis: a promising approach for treating lung carcinoma by Ziyang Wu, Yan Zhang, Wendi Zhong, Kunjian Wu, Tian Zhong, Tao Jiang

“…In addition, research on ferroptosis in the diagnosis and treatment of lung cancer has been growing exponentially. Therefore, it is necessary to provide a thorough summary of the latest advancements in the field of ferroptosis. …”
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A Structural Bioinformatics-Guided Study of Adenosine Triphosphate-Binding Cassette (ABC) Transporters and Their Substrates by Iqra Younus, Robert C. Ford, Stephen M. Prince

“…Human ABC transporters are closely linked to the pathogenesis of diseases such as cancer, metabolic diseases, and Alzheimer’s disease. …”
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A Simple Methodology for Conversion of Mouse Monoclonal Antibody to Human-Mouse Chimeric Form by Vinh T. Dang, Kedar D. Mandakhalikar, Oi-Wing Ng, Yee-Joo Tan

“…Passive immunotherapy has mainly been used as a therapy against cancer and inflammatory conditions. Recent studies have shown that monoclonal antibody-(mAb-) based passive immunotherapy is a promising approach to combat virus infection. …”
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Diffeomorphic Registration of Images with Variable Contrast Enhancement by Guillaume Janssens, Laurent Jacques, Jonathan Orban de Xivry, Xavier Geets, Benoit Macq

“…The method is validated in the context of radiotherapy for lung cancer patients on several 4D respiratory-correlated CT scans of the thorax with and without variable contrast enhancement.…”
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Generational Expression of Muir-Torre Syndrome in a Canadian Family by Kaitlin Alexandra Vanderbeck, R. Gary Sibbald, Nirosha Murugan

“…Muir-Torre syndrome (MTS) is a rare autosomal dominant inherited genodermatosis that is considered to be a phenotypic subtype of hereditary nonpolyposis colorectal cancer (HNPCC), commonly referred to as Lynch syndrome. …”
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Single-Cell Sequencing Technology in Oncology: Applications for Clinical Therapies and Research by Baixin Ye, Qingping Gao, Zhi Zeng, Creed M. Stary, Zhihong Jian, Xiaoxing Xiong, Lijuan Gu

“…Cellular heterogeneity is a fundamental characteristic of many cancers. A lack of cellular homogeneity contributes to difficulty in designing targeted oncological therapies. …”
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Dynamic Tracking of Lung Deformation during Breathing by Using Particle Method by Subas Chhatkuli, Seiichi Koshizuka, Mitsuru Uesaka

“…To reduce the side effects and to improve the efficiency of radiation therapy in lung cancer, a pinpoint radiation therapy system is under development. …”
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Antioxidant and anti-inflammatory roles of tea polyphenols in inflammatory bowel diseases by Van-Long Truong, Woo-Sik Jeong

“…High intake of tea polyphenols has been described to prevent and/or attenuate a variety of chronic pathological conditions like cardiovascular diseases, neurodegenerative diseases, diabetes, and cancer. This review focuses on established antioxidant and anti-inflammatory properties of tea polyphenols and underlying mechanisms of their involvement in inflammatory bowel diseases (IBD). …”
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Aldehyde Dehydrogenases: Not Just Markers, but Functional Regulators of Stem Cells by Giuseppe Vassalli

“…Over the past decade, high ALDH activity has been increasingly used as a selectable marker for normal cell populations enriched in stem and progenitor cells, as well as for cell populations from cancer tissues enriched in tumor-initiating stem-like cells. …”
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Comparative genomics reveal a novel phylotaxonomic order in the genus Fusobacterium by Cristian Molteni, Diego Forni, Rachele Cagliani, Manuela Sironi

“…Abstract Fusobacteria have been associated to different diseases, including colorectal cancer (CRC), but knowledge of which taxonomic groups contribute to specific conditions is incomplete. …”
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Differential Toxicity of DNA Adducts of Mitomycin C by Jill Bargonetti, Elise Champeil, Maria Tomasz

“…Evidence is reviewed that various adducts are capable of inducing different cell death pathways in cancer cells.This evidence is derived from a parallel study of MC and its derivatives 2,7-diaminomitosene (2,7-DAM) which is the main metabolite of MC and forms two mono-adducts with DNA, and decarbamoyl mitomycin C (DMC), which alkylates and cross-links DNA, predominantly with a chirality opposite to that of the DNA adducts of MC. 2,7-DAM is not cytotoxic and does not activate the p53 pathway while MC and DMC are cytotoxic and able to activate the p53 pathway. …”
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Acute Myeloid Leukemia (AML) Detection Using AlexNet Model by Maneela Shaheen, Rafiullah Khan, R. R. Biswal, Mohib Ullah, Atif Khan, M. Irfan Uddin, Mahdi Zareei, Abdul Waheed

“…Acute Myeloid Leukemia (AML) is a kind of fatal blood cancer with a high death rate caused by abnormal cells’ rapid growth in the human body. …”
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Calcium Alginate and Calcium Alginate-Chitosan Beads Containing Celecoxib Solubilized in a Self-Emulsifying Phase by Lorena Segale, Lorella Giovannelli, Paolo Mannina, Franco Pattarino

“…The rationale of this work was linked to the desire to improve celecoxib therapeutic effectiveness reducing its gastric adverse effects and to favor its use in the prophylaxis of colon cancer and as adjuvant in the therapy of familial polyposis. …”
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Investigation of photophysical properties and potential biological applications of substituted tris(polypyridyl)ruthenium(II) complexes by T. Sumitha Celin, G. Allen Gnana Raj, T. S. Prathima, M. M. Balamurali

“…Following the above, the anticancer properties were evaluated against breast cancer-related proteins. The results revealed that the complex possesses comparable anticancer and antioxidant potential to that of [Ru(bpy)3]2+. …”
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Induction of Cell Activation Processes by Low Frequency Electromagnetic Fields by Myrtill Simkó

“…Electromagnetic fields (EMF) such as those from electric power transmission and distribution lines (50/60 Hz) have been associated with increased risk of childhood leukemia, cancer of the nervous system, and lymphomas. Several in vitro studies on EMF effects were performed to clarify the existing controversies, define the risks, and determine the possible mechanisms of adverse effects. …”
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Paradigm shift in head and neck oncology patient management by Chiquit van Linden van den Heuvell, Florence van Zuuren, Mary Wells, Geert van der Laan, Harry Reintsema

“…Abstract Objective This article describes a paradigm shift in what is considered to be good care for patients living with and after (head and neck) cancer. HNO patients often experience severe and difficult physical and psychosocial problems due to the nature and location of the disease. …”
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Predicting appropriateness of antibiotic treatment among ICU patients with hospital-acquired infection by Ella Goldschmidt, Ella Rannon, Daniel Bernstein, Asaf Wasserman, Michael Roimi, Anat Shrot, Dan Coster, Ron Shamir

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A Simple and Rapid LC-MS/MS Method for Quantification of Total Daidzein, Genistein, and Equol in Human Urine by Shikha Saha, Paul A Kroon

“…Isoflavones and isoflavandiols have shown many health benefits, such as reducing cardiovascular disease, cancer, age-related disease, and osteoporosis. However, to investigate the relationships between consumption of isoflavones and their health benefits, it is important to be able to accurately quantify exposure in the large numbers of samples typically produced in association studies (i.e., several thousands). …”
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Rectal Ischemia Mimicked Tumor Mass by Nicolaos Zikos, Panagiota Aggeli, Evangelia Louka, George Pappas-Gogos

“…A percentage of 10%–20% of patients with ischemic colitis usually have a distal potentially obstructing lesion or disorder such as cancer, diverticulitis or fecal impaction. Ischemic colitis, when mucosal and submucosal edema is severe and hemorrhagic nodules are large enough, can mimic a neoplasmatic lesion. …”
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Design, Synthesis and Potential Anti-Proliferative Activity of Some Novel 4-Aminoquinoline Derivatives by Ghorab Mostafa M., Al-Said Mansour S., Arafa Reem K.

“…All the newly synthesized comounds were tested for in vitro antiproliferative activity against the MCF-7 breast cancer cell line. Seventeen of the novel compounds showed higher activity than the reference drug doxorubicin. …”
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