Brain gliomas new transcriptomic discoveries from differentially expressed genes to therapeutic targets by Shiwen Pei, Zhiquan Jiang, Hongwei Cheng

“…Gene set enrichment analysis and immunocytometric analysis further explored the biological functions and pathways of identified genes, which were validated using The Cancer Genome Atlas and Genotype-Tissue Expression datasets. …”
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Neurotrophic Receptor Tyrosine Kinase 2 (NTRK2) Alterations in Low-Grade Gliomas: Report of a Novel Gene Fusion Partner in a Pilocytic Astrocytoma and Review of the Literature by Siobhan S. Pattwell, Eric Q. Konnick, Yajuan J. Liu, Rebecca A. Yoda, Laligam N. Sekhar, Patrick J. Cimino

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ASPM Promotes the Progression of Anaplastic Thyroid Carcinomas by Regulating the Wnt/β-Catenin Signaling Pathway by Liang Jiang, Shuai Zhang, Ning An, Guoqing Chai, Changhong Ye

“…Abnormal spindle-like microcephaly-associated protein (ASPM) is closely correlated with several malignant tumors, whereas little is known about the role of ASPM in anaplastic thyroid cancer (ATC). Herein, we sought to investigate whether ASPM is involved in the pathogenesis of ATC and the underlying mechanisms. …”
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A Novel 8-Gene Prognostic Signature for Survival Prediction of Uveal Melanoma by Zhongjun Tang, Kebo Cai

“…In the validation phase, the signature was validated in The Cancer Genome Atlas database. Results. Forty-one genes were identified as hub genes of metastasis by WGCNA. …”
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Renal Tubular Acidosis an Adverse Effect of PD-1 Inhibitor Immunotherapy by Sandy El Bitar, Chanudi Weerasinghe, Elie El-Charabaty, Marcel Odaimi

“…We report the case of a 79-year-old female with metastatic non-small cell lung cancer on anti-PD-1 therapy nivolumab. After the 4th administration of nivolumab, the treatment course was complicated with normal anion gap metabolic acidosis. …”
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A Novel del(20q) in Aggressive Nodal Marginal Zone Lymphoma by Jason B. Kern, Deiter J. Duff, Jamie L. Odem, Magda Esebua, Lisa R. Smith, Donald Doll, Michael Wang

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In-silico tool based on Boolean networks and meshless simulations for prediction of reaction and transport mechanisms in the systemic administration of chemotherapeutic drugs. by Fabián Mauricio Vélez Salazar, Iván David Patiño

“…Subsequently, a Boolean model is developed to determine the presence, interaction and rates of RTMs based on the comparison of the spatio-temporal evolution of the drug concentration ratios, being this the main contribution of the present work to the comprehension of the phenomena involved in the systemic administration of chemotherapeutic drugs in cancer tumors. Different combinations of E (0 kV/m, 46 kV/m, 70 kV/m), λinl (1x10-4m/s, 1x10-3m/s, 1x10-2m/s) and PK (One-short tri-exponential, mono-exponential) are examined. …”
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SHP2-Mediated Signal Networks in Stem Cell Homeostasis and Dysfunction by Chen Kan, Fan Yang, Siying Wang

“…Gain-of-function (GOF) or loss-of-function (LOF) SHP2 in various cells, especially for stem cells, disrupt organism self-balance and lead to a plethora of diseases, such as cancer, maldevelopment, and excessive hyperblastosis. …”
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Inhibitory effect of taspine derivative TAD1822-7 on tumor cell growth and angiogenesis via suppression of EphrinB2 and related signaling pathways by Liu Rui, Yu Runze, Cui Yuxin, Fan Mengying, Wang Bo, Zhang Yanmin

“…The aim of this study was to investigate the inhibitory effect of TAD1822-7, a synthesized taspine derivative, on cancer through its effects on tumor cell growth and angiogenesis via suppression of EphrinB2. …”
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Naringenin induces ferroptosis in osteosarcoma cells through the STAT3-MGST2 signaling pathway by Yingang Li, Xizhuang Bai

“…Naringenin is a flavonoid known for its anti-cancer properties, yet its role in osteosarcoma has not been thoroughly studied. …”
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Heavy Metal Content and Health Risk Assessment of Some Selected Medicinal Plants from Obuasi, a Mining Town in Ghana by Flora Amerley Amarh, Eric Selorm Agorku, Ray Bright Voegborlo, Gerheart Winfred Ashong, Enoch Nii Klu Nortey, Napoleon Jackson Mensah

“…Results obtained from hazard indices such as the hazard quotient and carcinogenic risk show that the medicinal plants are not likely to cause cancer if they are consumed over a prolonged period of time.…”
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Extramedullary Hematopoiesis in a Sentinel Lymph Node as an Early Sign of Chronic Myelomonocytic Leukemia by Joslin M. Bowen, Anamarija M. Perry, Erin Quist, Mojtaba Akhtari

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Contemporary Approaches to the Treatment of Gastroesophageal Reflux Disease by Boris D. Starostin

“…In the presence of Barrett’s esophagus, this measure is considered from the standpoint of cancer prevention.Conclusion. The use of PPIs is considered to be the key approach in the drug treatment of GERD. …”
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New Insights into Chemical Profiles and Health-Promoting Effects of Edible Mushroom <i>Dictyophora indusiate</i> (Vent ex. Pers.) Fischer: A Review by Yogesh Kumar, Baojun Xu

“…Mushrooms help regulate metabolism and improve lipid profiles, with potential applications in managing metabolic disorders, cancer, cardiovascular diseases, diabetes, and neurodegenerative conditions. …”
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Metástasis ósea como presentación del linfoma de Hodgkin. Reporte de un caso by Dianelí Lorely Reyes Hernández, Lidia Brito Martínez, Roselí González Cruz

“…Dada la poca frecuencia de estos casos se considera necesaria su publicación para alertar sobre la inclusión de este pensamiento diagnóstico en pacientes que presentan dolores óseos como inicio de un cáncer aún no diagnosticado.…”
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BEHAVIOUR AMONG FEMALE MIGRANTS IN MAKURDI, BENUE STATE by ONYEMA ANGELA ABEL

“…Increased alcohol consumption, depression, suicides, cancer, unwanted pregnancies, STDs are all consequences of risky sexual behavior. …”
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Gene-Gene Interaction Analysis for the Accelerated Failure Time Model Using a Unified Model-Based Multifactor Dimensionality Reduction Method by Seungyeoun Lee, Donghee Son, Wenbao Yu, Taesung Park

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Nicotine Impairs the Response of Lung Epithelial Cells to IL-22 by Hannah My-Hanh Nguyen, Jaclene Amber Torres, Sudhanshu Agrawal, Anshu Agrawal

“…Smoking is a major risk factor for pulmonary diseases that include chronic obstructive pulmonary diseases (COPD) and cancer. Nicotine is the toxic and addictive component of tobacco products, like cigarettes, that negatively affects the immune system. …”
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Current Treatment Approaches to HCC with a Special Consideration to Transplantation by N. Bhardwaj, M. T. P. R. Perera, M. A. Silva

“…Hepatocellular carcinoma (HCC) is the third leading cause of cancer deaths worldwide. The mainstay of treatment of HCC has been both resectional and transplantation surgery. …”
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Harnessing the power of seaweed: unveiling the potential of marine algae in drug discovery by Leonel Pereira, Ana Valado

“…Seaweeds have demonstrated particular promise in the areas of cancer research, with certain species showing potent antitumor properties. …”
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