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9181
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9182
MicroRNA-Based Markers of Oral Tongue Squamous Cell Carcinoma and Buccal Squamous Cell Carcinoma: A Systems Biology Approach
Published 2023-01-01“…Oral tongue squamous cell carcinoma (OTSCC) and buccal squamous cell carcinoma (BSCC) are the first and second leading causes of oral cancer, respectively. OTSCC and BSCC are associated with poor prognosis in patients with oral cancer. …”
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9183
A dynamic co-expression approach reveals Gins2 as a potential upstream modulator of HNSCC metastasis
Published 2025-01-01“…Abstract Head and neck squamous cell carcinoma (HNSCC) is an aggressive cancer that is notably associated with a high risk of lymph node metastasis, a major cause of cancer mortality. …”
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9184
Evaluating the impact of COVID-19 protection measures and staff absence on radiotherapy practice: A simulation study.
Published 2025-01-01“…<h4>Background</h4>Radiotherapy practice for cancer treatment is resource-intensive and demands optimised processes for patient throughput while guaranteeing the quality and safety of the therapy. …”
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9185
A New Pyrrolidone Alkaloid and Other Constituents from Rourea oligophlebia Stems
Published 2021-01-01“…Compound 11 exhibited good antimicrobial activity on Gram (+) strains and moderate cytotoxicity against KB, Hep-G2, and LU cancer cell lines. Compounds 6 and 8–10 showed selective activity on HepG-2 and MCF-7 over KB and LU cancer cell lines, while compound 7 exhibited similar effects on KB, HepG-2, and MCF-7 cell lines with IC50 values of 36.46 ± 0.81, 32.00 ± 0.58, and 32.03 ± 0.61 µg/mL, respectively.…”
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9186
Pegylated NIR Fluorophore-Conjugated OBHSA Prodrug for ERα-Targeted Theranostics with Enhanced Imaging and Long-Term Retention
Published 2025-01-01“…OBHSA-PEG-DCM holds promise as a theranostic agent for ERα-positive breast cancer, offering both therapeutic and diagnostic capabilities. …”
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9187
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9188
Comparing simple and functional jejunal interposition with preserved duodenal passage after total gastrectomy
Published 2025-02-01“…Conclusion: This study shows that both FJI and SJI are effective at maintaining nutrition, quality of life, and survival rate after total gastrectomy for gastric cancer. Although FJI is more complex, SJI is preferred due to its shorter duration. …”
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9189
EXO1 is a key gene for lung-resident memory T cells and has diagnostic and predictive values for lung adenocarcinoma
Published 2025-02-01“…An increasing number of studies indicated that tissue-resident memory T (TRM) cells played significant roles in anti-cancer immunity. In our previous study, EXO1 was found to be a core gene for TRM cells in the prognosis of LUAD. …”
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9190
The effect of consuming bread contaminated with heavy metals on cardiovascular disease and calculating its risk assessment
Published 2025-01-01“…The findings indicated that bread intake in the study region is not correlated with non-carcinogenic or carcinogenic risks, since the cancer risk and incremental lifetime cancer risk for both groups were below 1*10^-6. …”
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9191
Concurrent Viewing of H&E and Multiplex Immunohistochemistry in Clinical Specimens
Published 2025-01-01“…<b>Results:</b> Application is made to several clinically relevant specimens, including breast cancer (HER2, ER, and PR), prostate cancer (PSMA, P504S, basal cell, and CD8), Hodgkin’s lymphoma (CD15 and CD30), and melanoma (LAG3). …”
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9192
Capivasertib enhances chimeric antigen receptor T cell activity in preclinical models of B cell lymphoma
Published 2025-03-01“…Phosphatidylinositol 3-kinase (PI3K)/protein kinase B (AKT) signaling is involved in the growth of normal and cancer cells and is crucial for T cell activation. …”
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9193
Heavy metal concentrations in fishes from Zakrzówek Reservoir and the Vistula River near Kraków: Human risk assessment
Published 2024-07-01“…Metal pollution index (MPI), estimated daily intake (EDI), target hazard quotient (THQ), and hazard index (HI) analyses showed no significant non-carcinogenic risk to human health from the consumption of the muscle meat of the fishes analyzed. Cancer risk (CR) values, calculated based on maximum Ni concentrations in fish muscle tissue, did not exceed the upper limit of the acceptable cancer risk range. …”
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9194
M cells targeted H. pylori antigen SAM-FAdE displayed on bacterium-like particles induce protective immunity
Published 2025-01-01“…Abstract Background Helicobacter pylori (H. pylori), a specific bacterium capable of surviving in the acidic environment of the stomach, has been recognized as a group of causative agents of gastric cancer. Therefore, the development of mucosal vaccines against H. pylori is expected to provide an important direction for the treatment of chronic gastritis and the prevention of gastric cancer. …”
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Multi-stage structure-based virtual screening approach combining 3D pharmacophore, docking and molecular dynamic simulation towards the identification of potential selective PARP-1...
Published 2025-02-01“…Abstract Presently, humanity is confronted with a range of diseases that have high death rates, especially those linked to cancerous growths. Several enzymes and proteins have been discovered as highly attractive targets for cancer treatment. …”
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9197
A Review on Bioactive Phytochemical Constituents and Pharmacological Activities of Aegiceras corniculatum: A Pharmaceutically Important Mangrove Plant
Published 2024-01-01“…These phenolic chemicals also reduce oxidative stress and help treat cancer and other inflammatory diseases. The extract of this plant activates the κ-opioid receptor, causing central antinociception. …”
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9198
Preoperative Thrombocytopenia May Predict Poor Surgical Outcome after Extended Hepatectomy
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9199
Antitumor Activity of Whole-Plant Extracts from In Vitro Cultured and Wild-Growing <i>Clinopodium vulgare</i> Plants on a Panel of Human Tumor Cell Lines
Published 2025-01-01“…The ability of <i>C. vulgare</i> to inhibit cancer cell migration and induce apoptosis in the tumor cells was examined by wound healing assay and fluorescence microscopic methods. …”
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9200
Discovery of novel serum peptide biomarkers for cholangiocarcinoma recurrence through MALDI-TOF MS and LC–MS/MS peptidome analysis
Published 2025-01-01“…Abstract Cholangiocarcinoma (CCA) is an aggressive cancer originating from bile duct epithelial cells, with a high rate of recurrence following surgical resection. …”
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