Persistent effects of legal status on healthcare access and outcomes: findings from a state-wide representative cross-sectional survey in California by Lei Chen, Michelle Kao Nakphong, May Sudhinaraset, Nadereh Pourat, Maria-Elena De Trinidad Young

Get full text

RITUXIMAB VERSUS SPLENECTOMY IN CHRONIC PRIMARY ITP: EXPERIENCE OF A SINGLE HEMATOLOGY CLINIC by Rawanda Shamoon, Ahmed Khudair Yassin, Sarah Laith Alnuaimi

Get full text

Distinct Chromosomal Profiles in Metastasizing and Non-Metastasizing Colorectal Carcinomas by B. Michael Ghadimi, Marian Grade, Carsten Mönkemeyer, Bettina Kulle, Jochen Gaedcke, Bastian Gunawan, Claus Langer, Torsten Liersch, Heinz Becker

“…Background: The prognosis of colorectal cancer patients is to a considerable extent determined by the metastatic potency of the primary tumor. …”
Get full text

Evaluating Medicinal Plants for Anticancer Activity by Elisha Solowey, Michal Lichtenstein, Sarah Sallon, Helena Paavilainen, Elaine Solowey, Haya Lorberboum-Galski

“…Most chemotherapeutic drugs for cancer treatment are molecules identified and isolated from plants or their synthetic derivatives. …”
Get full text

Chronic Gastritis in Dermatitis Herpetiformis: A Controlled Study by Anna Alakoski, Teea T. Salmi, Kaisa Hervonen, Hannu Kautiainen, Maarit Salo, Katri Kaukinen, Timo Reunala, Pekka Collin

“…Atrophic gastritis may increase the risk of gastric cancer. We advocate performing upper endoscopy with sufficient histologic samples in DH.…”
Get full text

Morbidity and Mortality Outcomes of Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy at a Single Institution in Japan by Akiyoshi Mizumoto, Emel Canbay, Masamitsu Hirano, Nobuyuki Takao, Takayuki Matsuda, Masumi Ichinose, Yutaka Yonemura

“…Total of 284 procedures of CRS were performed on patients with pseudomyxoma peritonei, peritoneal carcinomatosis (PC) from colon cancer and gastric cancer between 2007 and 2011 in our institution. …”
Get full text

Adjuvant Radiochemotherapy with a 23-Month Overall Survival Time in a Patient after a Surgery due to Splenic Hemangiosarcoma Rupture: A Case Report with the Literature Review by M. Bilski, D. Surdyka, I. Paśnik, M. Bilska, P. Cisek, P. Korona, J. Szumiło, L. Grzybowska-Szatkowska

“…The case shows that adjuvant radiotherapy as part of cancer treatment strategy may prolong the overall survival.…”
Get full text

Risk Factors for Predicting Lymph Nodes Posterior to Right Recurrent Laryngeal Nerve (LN-prRLN) Metastasis in Thyroid Papillary Carcinoma: A Meta-Analysis by Cunfu Li, Jun Xiang, Yunjun Wang

Get full text

Microwave Imaging Using CMOS Integrated Circuits with Rotating 4 × 4 Antenna Array on a Breast Phantom by Hang Song, Afreen Azhari, Xia Xiao, Eiji Suematsu, Hiromasa Watanabe, Takamaro Kikkawa

“…A digital breast cancer detection system using 65 nm technology complementary metal oxide semiconductor (CMOS) integrated circuits with rotating 4 × 4 antenna array is presented. …”
Get full text

Effects of Nonsurgical Periodontal Therapy on Clinical Response, Microbiological Profile, and Glycemic Control in Malaysian Subjects with Type 1 Diabetes by Samira Mukhtar Buzinin, Aied Mohammed Alabsi, Alexander Tong Boon Tan, Vui King Vincent-Chong, Dasan Swaminathan

Get full text

Food Safety Analysis of Milk and Beef in Southwestern Uganda by Phyllis Candy, Natabo, Keneth Iceland, Kasozi, Sarah, Namubiru, Dickson Stuart, Tayebwa, Andrew, Tamale, Pwaveno H., Bamaiyi

“…In this study, we established levels of lead (Pb), zinc (Zn), cadmium (Cd), copper (Cu), and iron (Fe) in milk and beef and obtained the estimated daily intake (EDI) and incremental lifetime cancer risk (ILCR) as measures of risk to the Ugandan population. …”
Get full text

Porto Alegre Line predicts lenticulostriate arteries encasement and extent of resection in insular gliomas. A preliminary study by Gustavo Rassier Isolan, Gustavo Rassier Isolan, Gustavo Rassier Isolan, Samir Ale Bark, Samir Ale Bark, Jander Moreira Monteiro, Jander Moreira Monteiro, Tobias A. Mattei, Kaan Yağmurlu, Rafaela Fernandes Gonçalves, Rafaela Fernandes Gonçalves, Osvaldo Malafaia, Rafael Roesler, Rafael Roesler, Rafael Roesler, Jurandir Marcondes Ribas Filho

Get full text

Machine learning based on blood test biomarkers predicts fast progression in advanced NSCLC patients treated with immunotherapy by Jie Yang, Jian-Guo Zhou, Benjamin Frey, Hu Ma, Haitao Wang, Markus Hecht, Rainer Fietkau, Udo Gaipl, Xiaofei Chen, Ada Hang-Heng Wong, Fangya Tan, Si-Si He, Gang Shen, Yun-Jia Wang, Wenzhao Zhong

“…Objective Fast progression (FP) represents a desperate situation for advanced non-small cell lung cancer (NSCLC) patients undergoing immune checkpoint inhibitor therapy. …”
Get full text

Detection of Circulating Tumor DNA in Patients with Thyroid Nodules by Krupal B. Patel, Nicholas Cormier, James Fowler, Allison Partridge, Julie Theurer, Morgan Black, Nicole Pinto, John Yoo, Kevin Fung, Danielle MacNeil, William Stecho, Christopher Howlett, Muriel Brackstone, John W. Barrett, Anthony Nichols

“…Detection of circulating tumor DNA (ctDNA) in cancer patients can potentially serve as a noninvasive, sensitive test of disease status. …”
Get full text

Economic Evaluation of Robotic-assisted Radical Prostatectomy: A Systematic Review and Meta-analysis by Tanan Bejrananda, Win Khaing, Sajesh K. Veettil, Therdpong Thongseiratch, Nathorn Chaiyakunapruk

“…The findings of this review can support decision-making for prostate cancer treatment options.…”
Get full text

Long-Term Analysis of Recurrence Beyond Milan Criteria Following Ablation of Solitary Early-Stage Hepatocellular Carcinoma ≤3 cm in Potentially Transplantable Patients: A Over 1... by Chen S, Qi H, Tan H, Cao F, Xie L, Huang T, Wu Y, Wen C, Wang Y, Shen L, Fan W

“…Shuanggang Chen,1,2,* Han Qi,1,2,* Hongtong Tan,1,2,* Fei Cao,1,2 Lin Xie,1,2 Tao Huang,1,2 Ying Wu,3 Chunyong Wen,1,2 Yujia Wang,1,2 Lujun Shen,1,2 Weijun Fan1,2 1Department of Minimally Invasive Interventional Therapy, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, People’s Republic of China; 2State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for cancer, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, People’s Republic of China; 3Department of Interventional Therapy, Shenzhen second People’s Hospital, The First Affiliated Hospital of Shenzhen University, Shenzhen, 518035, People’s Republic of China*These authors contributed equally to this workCorrespondence: Weijun Fan, Email fanwj@sysucc.org.cn; Lujun Shen, Email shenlj@sysucc.org.cnBackground: Salvage liver transplantation is promising for hepatocellular carcinoma(HCC) recurrence post-ablation but is significantly affected by recurrence beyond Milan Criteria (RBM).Materials and Methods: A retrospective cohort study of potentially transplantable HCC patients undergoing ablation between 2007 and 2017 assessed median time to recurrence beyond Milan Criteria(TRBM) via Kaplan-Meier curves and predictive capacity of recurrence and RBM for overall survival(OS) via Receiver Operating Characteristic Curves, and identified independent risk factors for TRBM and RBM via Cox and binary logistic regression models.Results: We enrolled 191 potentially transplantable patients with early-stage HBV-related HCC ≤ 3 cm who underwent ablation. …”
Get full text

Associations between night-time sleep duration and fasting glucose and ratio of triglyceride to high-density lipoprotein cholesterol among adults free of type 2 diabetes or without... by Rong Zhang, Li Zhang, Qiang Li, Minying Zhang, Feng Liu, Shuo Chen, Yu-Jie Niu, Xin Qi, Chunjun Li, Jiangshan He, Chenglin Hong, Yuxue Wang, Yaqi Fan, Pei Guo, Binbin Zhang, Shitao Ma, Mianzhi Zhang

Get full text

Hypoxia-tropic delivery of nanozymes targeting transferrin receptor 1 for nasopharyngeal carcinoma radiotherapy sensitization by Ruofei Zhang, Yanfang Shen, Xiaoying Zhou, Jianru Li, Hanqing Zhao, Zixia Zhang, Jun Zhao, Hongjun Jin, Shuanshuan Guo, Hui Ding, Guohui Nie, Zhe Zhang, Ying Wang, Xiyun Yan, Kelong Fan

Get full text

Wilms tumor primary cultures capture phenotypic heterogeneity and facilitate preclinical screening by Lisa Götz, Jenny Wegert, Alireza Paikari, Silke Appenzeller, Sabrina Bausenwein, Christian Vokuhl, Taryn D. Treger, Jarno Drost, Christin Linderkamp, Dominik T. Schneider, Karen Ernestus, Steven W. Warman, Jörg Fuchs, Nils Welter, Norbert Graf, Sam Behjati, Rhoikos Furtwängler, Manfred Gessler

“…Sensitivity was related to MYCN status, a marker associated with adverse outcome across human cancers including WT. The combination of the three culture techniques represents a promising tool to both explore tumor heterogeneity in vitro and to facilitate characterization of candidate driver genes, in order to improve treatment regimens in the future.…”
Get full text

Regulation of human papillomavirus E6 oncoprotein function via a novel ubiquitin ligase FBXO4 by Arushi Vats, Luca Braga, Nezka Kavcic, Paola Massimi, Edoardo Schneider, Mauro Giacca, Laimonis A. Laimins, Lawrence Banks

“…This study, for the first time, identifies a novel ubiquitin ligase, FBXO4 that targets the degradation of HPV E6 oncoprotein in the absence of E6AP in cervical cancer-derived cell lines. This may have significant implications for our understanding of HPV-associated cancers by providing deeper insights into the intricate interplay between viral proteins and host cellular machinery and the development of targeted therapies.…”
Get full text