Showing 361 - 380 results of 1,915 for search '"cancer"', query time: 0.06s Refine Results
  1. 361
  2. 362
  3. 363

    Discrete vulnerability to pharmacological CDK2 inhibition is governed by heterogeneity of the cancer cell cycle by Vishnu Kumarasamy, Jianxin Wang, Michelle Roti, Yin Wan, Adam P. Dommer, Hanna Rosenheck, Sivasankar Putta, Alec Trub, John Bisi, Jay Strum, Patrick Roberts, Seth M. Rubin, Costakis Frangou, Karen McLean, Agnieszka K. Witkiewicz, Erik S. Knudsen

    Published 2025-02-01
    “…Abstract Cyclin dependent kinase 2 (CDK2) regulates cell cycle and is an emerging target for cancer therapy. There are relatively small numbers of tumor models that exhibit strong dependence on CDK2 and undergo G1 cell cycle arrest following CDK2 inhibition. …”
    Get full text
    Article
  4. 364

    Improving neuroendocrine tumor treatments with mathematical modeling: lessons from other endocrine cancers by John Metzcar, Rachael Guenter, Yafei Wang, Kimberly M Baker, Kate E Lines

    Published 2025-02-01
    “…Causal or mechanistic mathematical modeling is widely deployed in disease areas such as breast and prostate cancers, aiding the understanding of observations and streamlining in vitro and in vivo modeling efforts. …”
    Get full text
    Article
  5. 365
  6. 366
  7. 367
  8. 368

    Real-World Treatment Patterns in Men with Castration- Resistant Prostate Cancer Receiving Docetaxel by Keith L. Davis, Benjamin Gutierrez, Teresa Zyczynski, James A. Kaye

    Published 2015-01-01
    “…**Background:** Docetaxel has been a standard of care for castration-resistant prostate cancer (CRPC) in the United States since 2004, yet little has been reported on its patterns of use in routine practice. …”
    Get full text
    Article
  9. 369
  10. 370
  11. 371

    Accelerated failure model with empirical analysis and application to colon cancer data: Testing and validation by John Abonongo, Anuwoje Ida L. Abonongo, Abdussalam Aljadani, Mahmoud M. Mansour, Haitham M. Yousof

    Published 2025-02-01
    “…Application of the proposed model to a colon cancer dataset reveal its superior parametric fit compared to the Cox proportional hazards (Cox-PH) model and other competing AFT models, as indicated by information criteria and goodness-of-fit measures. …”
    Get full text
    Article
  12. 372
  13. 373
  14. 374

    Effect of cytotoxic CD8+ T-cells secretory proteins on hypoxic pancreatic cancer cells. by Eiman Abdo, Mohammad A Ismail, Sabal Al Hadidi, Mairvat Al-Mrahleh, Tareq Saleh, Malik Zihlif, Nidaa A Ababneh

    Published 2025-01-01
    “…<h4>Background</h4>Hypoxia in tumor cells is linked to increased drug resistance and more aggressive behavior. In pancreatic cancer, the tumor microenvironment is notably hypoxic and exhibits strong immunosuppressive properties. …”
    Get full text
    Article
  15. 375
  16. 376

    A comprehensive analysis of deep learning and transfer learning techniques for skin cancer classification by Manishi Shakya, Ravindra Patel, Sunil Joshi

    Published 2025-02-01
    “…This research focus on skin cancer images and provides solution using deep learning approaches. …”
    Get full text
    Article
  17. 377
  18. 378
  19. 379
  20. 380