Surgical Treatment Intensity at the End of Life in Patients With Cancer: A Systematic Review by Samuel Lawday, BMBS, MByRes, Benjamin E. Zucker, MA, MBBS, MRCS, Shona Gardner, MBChB, MRCS, James Robb, MBChB, MA, Lorna Leandro, MA, BM, BCh, William Hollingworth, PhD, Jane Blazeby, MBChB, MD, Angus G.K. McNair, PhD, FRCS, Charlotte Chamberlain, PhD, MRCP

“…Concern regarding overly ‘aggressive’ care or high health care utilization at the EoL, particularly in cancer, is growing. The contribution surgery makes to the quality and cost of EoL care in cancer has not yet been quantified. …”
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Artificial intelligence propels lung cancer screening: innovations and the challenges of explainability and reproducibility by Mario Mascalchi, Chiara Marzi, Stefano Diciotti

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Distinct MicroRNA Subcellular Size and Expression Patterns in Human Cancer Cells by Beibei Chen, Bo Zhang, Huaxia Luo, Jiao Yuan, Geir Skogerbø, Runsheng Chen

“…Here, we show distinct genome-wide sub-cellular localization distribution profiles of small noncoding RNAs in human breast cancer cells. Methods. We separated breast cancer cell nuclei from cytoplasm, and identified small RNA sequences using a high-throughput sequencing platform. …”
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Prioridades e Desafios para a Prevenção e Vigilância do Câncer by Gulnar Azevedo e Silva, Roberto de Almeida Gil

“… O editorial enfoca o peso do câncer no mundo e no Brasil, contextualizando as principais questões envolvidas na projeção da incidência dos diversos tipos, bem como no conhecimento científico que vem sendo acumulado em termos de prevenção. …”
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Neoadjuvant chemoradiotherapy up-regulates PD-L1 in radioresistant colorectal cancer by Sung Uk Bae, Hye Won Lee, Jee Young Park, Incheol Seo, Jae-Min Cho, Jin Young Kim, Ju Yup Lee, Yoo Jin Lee, Seong Kyu Baek, Nam Kyu Kim, Sang Jun Byun, Shin Kim

Subjects: “…Locally advanced rectal cancer…”
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Effect of Propolis on PPP2R1A and Apoptosis in Cancer Cells by Burak Durmaz, Latife Merve Oktay Çelebi, Ayşe Çekin, Ayshan Ahadova, Nur Selvi Günel, Hatice Kalkan Yıldırım, Ali Mert Özgönül, Eser Yıldırım Sözmen

“…Recently, it has been shown that protein phosphatase 2A (PP2A) dysfunction was common in many cancer types and was mediated by various inactivation mechanisms. …”
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Anti-lung Cancer Mechanism of Quercetin Based on Network Pharmacology and Experimental Validation by Yi WANG, Xiaofang PU

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Lung and Gut Microbiota as Potential Hidden Driver of Immunotherapy Efficacy in Lung Cancer by Carmine Carbone, Geny Piro, Vincenzo Di Noia, Ettore D’Argento, Emanuele Vita, Miriam Grazia Ferrara, Sara Pilotto, Michele Milella, Giovanni Cammarota, Antonio Gasbarrini, Giampaolo Tortora, Emilio Bria

“…Lung cancer is one of the deadliest and most common malignancies in the world, representing one of the greatest challenges in cancer treatment. …”
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Humoral Immune Response to Keyhole Limpet Haemocyanin, the Protein Carrier in Cancer Vaccines by A. Kantele, M. P. Häkkinen, J. Zivny, C. O. Elson, J. Mestecky, J. M. Kantele

“…KLH serving as protein carrier in several vaccines, the homing profile of KLH-specific response may be applicable to the cancer antigen parts in the same vaccines. The present data reflect a systemic homing profile, which appears advantageous for the targeting of immune response to cancer vaccines.…”
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Cardiac Effects of Thyrotropin Oversuppression with Levothyroxine in Young Women with Differentiated Thyroid Cancer by Kyung-Soon Hong, Jung-Woo Son, Ohk Hyun Ryu, Moon-Gi Choi, Ji Yeon Hong, Seong Jin Lee

“…We investigated the cardiac effects of TSH (thyroid-stimulating hormone) oversuppression in women with thyroidectomized differentiated thyroid cancer (DTC) during levothyroxine suppression therapy. …”
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The Importance of CD44 as a Stem Cell Biomarker and Therapeutic Target in Cancer by Ranjeeta Thapa, George D. Wilson

“…CD44 is a compelling marker for cancer stem cells of many solid malignancies. In addition, interaction of HA and CD44 promotes EGFR-mediated pathways, consequently leading to tumor cell growth, tumor cell migration, and chemotherapy resistance in solid cancers. …”
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Neutrophil to Lymphocyte Ratio as a Predictive Factor in Iraqi Patients with Thyroid Cancer by Fatima Falah Hassan, Wafaa Fadhil Hamed, Luma Yousif Mehdi

“… Thyroid cancer is one of the fastest growing malignancies in recent years, with an increase of 14.51% per year. …”
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The Impact of COVID-19 Pandemic on the Diagnosis, Treatment, and Outcomes of Colorectal Cancer in Singapore by Hui Lionel Raphael Chen, Piea Peng Lee, Yun Zhao, Wei Hao Caleb Ng, Jiashen Zhao, Yu En Christopher Tan, Bo Jie Sean Loh, Kah-Hoe Pierce Chow, Hiang Khoon Tan, Kwong-Wei Emile Tan

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Experimental approach to obtaining subcutaneous xenograft of non-small cell lung cancer by E. A. Lukbanova, M. V. Mindar, E. A. Dzhenkova, A. Yu. Maksimov, A. S. Goncharova, Yu. S. Shatova, A. A. Maslov, A. V. Shaposhnikov, E. V. Zaikina, Yu. N. Lazutin

Subjects: “…non-small cell lung cancer…”
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A Comparison of Cholesterol Uptake and Storage in Inflammatory and Noninflammatory Breast Cancer Cells by Breonna J. Martin, Kenneth L. van Golen

“…International Journal of Breast Cancer…”
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Development and test of reliability and validity of the Health Belief Scale for Prostate Cancer Screening by YU Lina, LUO Cui, LIU Shuangtai, XU Huan, LI Xiaoyan, ZHANG Xiaomeng, WANG Ting

Subjects: “…prostate cancer…”
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A Primer on the Role of TP53 Mutation and Targeted Therapy in Endometrial Cancer by Bohao Zhang, Haozhe Zhang, Yanru Qin

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A Rare Case of Endometrial Cancer Metastatic to the Sigmoid Colon and Small Bowel by Jeffrey A. Hubers, Anurag Soni

“…Metastatic endometrial cancer to the small bowel or colon has been described but is quite rare. …”
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Toxicology and Disease/Cancer Therapy in Reactive Oxygen Species-Mediated Drugs and Treatments by Hsueh-Wei Chang, Shao-Yu Chen, Li-Yeh Chuang, Sanjay Guleria

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Magnitude of cancer-associated thrombosis in Africa: A systematic review and meta-analysis by Astewle Andargie Baye, Agimasie Tigabu, Yirgalem Abere, Birara Ayichew Tilaye, Demewoz Kefale, Lakachew Yismaw Bazezew, Birhanu Mengist Munie, Berihun Bantie, Abebu Tegenaw Delie, Dessalegn Haile

“…Summary: Comprehensive data on the epidemiology of cancer-related thrombosis in Africa has been sparse until recently. …”
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