Effect of Trandolapril on Regression of Retinopathy in Hypertensive Patients with Type 2 Diabetes: A Prespecified Analysis of the Benedict Trial by Piero Ruggenenti, Ilian Iliev, Marco Filipponi, Stefano Tadini, Annalisa Perna, Maria Ganeva, Bogdan Ene-Iordache, Paolo Cravedi, Roberto Trevisan, Antonio Bossi, Giuseppe Remuzzi

“…Concomitant treatment with or without Non-Dihydropyridine Calcium Channel Blockers (ndCCBs) did not appreciably affect the incidence of retinopathy regression. …”
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Characteristics, Mortality, and Clinical Outcomes of Hospitalized Patients with COVID-19 and Diabetes: A Reference Single-Center Cohort Study from Poland by Michał Kania, Konrad Mazur, Michał Terlecki, Bartłomiej Matejko, Jerzy Hohendorff, Zlata Chaykivska, Mateusz Fiema, Marianna Kopka, Małgorzata Kostrzycka, Magdalena Wilk, Tomasz Klupa, Przemysław Witek, Barbara Katra, Marek Klocek, Marek Rajzer, Maciej T. Malecki

“…Factors contributing to lower mortality were in-hospital use of statin, thiazide diuretic, and calcium channel blocker. Conclusion. In this large COVID-19 cohort, DPs constituted more than a quarter of hospitalized patients. …”
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Effects of rosemary extract and its residue on production, immune performance, and gut microbiota in geese by Yuzhi Huang, Lanmeng Xu, Hang He, Lijuan Peng, Qinfeng Liao, Kun Wan, Simeng Qin, Lijing Cao, Jie Zhang

“…Moreover, for both RE and RR treatments, semi-eviscerated, eviscerated weights, and calcium apparent digestibility increased significantly, along with a decrease in the duodenal index (p < 0.05). …”
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Modified Delphi expert elicitation of the clinical and economic burden of obstructive hypertrophic cardiomyopathy in England and Northern Ireland by Faizel Osman, Michael Hurst, Belinda Sandler, Taryn Krause, Carla Zema, Teresa Lemmer, Kathleen Noon, Deepak Alexander

“…Prescription of beta-blockers was higher than calcium channel blockers, irrespective of NYHA class.Conclusions Treatment of obstructive HCM is associated with a substantial clinical and economic burden in England and Northern Ireland; the burden of the disease increasing with NYHA class is driven by the need for intensive disease management, hospitalisations and the potential burden of undertaking SRTs.…”
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An Evaluation of the Biocompatibility and Chemical Properties of Two Bioceramic Root Canal Sealers in a Sealer Extrusion Model of Rat Molars by Shintaro Takahara, Naoki Edanami, Razi Saifullah Ibn Belal, Kunihiko Yoshiba, Shoji Takenaka, Naoto Ohkura, Nagako Yoshiba, Susan Gomez-Kasimoto, Yuichiro Noiri

“…Furthermore, the extruded EBC and NBG became calcium- and phosphorus-rich, showing a Raman band for hydroxyapatite on Day 28. …”
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Gender inequalities in prescribing and initiation patterns of guideline-recommended drugs after acute myocardial infarction by Irene López-Ferreruela, Sara Malo, Blanca Obón-Azuara, María José Rabanaque, Adriana Gamba, Sara Castel-Feced, Isabel Aguilar-Palacio

“…Comedications such as rivaroxaban and calcium channel blockers were more likely to be prescribed in women. …”
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Impact of rock mineralogy on reactive transport of CO2 during carbon sequestration in a saline aquifer by Mohamed Gamal Rezk, Ahmed Farid Ibrahim

“…Anorthite dissolution provides ions for kaolinite precipitation, and the release of calcium ions from anorthite dissolution contributes to carbonate minerals precipitation. …”
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Decreased S100A9 Expression Promoted Rat Airway Smooth Muscle Cell Proliferation by Stimulating ROS Generation and Inhibiting p38 MAPK by Lei-Miao Yin, Xiao-Jie Han, Ting-Ting Duan, Yu-Dong Xu, Yu Wang, Luis Ulloa, Yong-Qing Yang

“…Our previous study showed that S100A9 (S100 calcium-binding protein A9; 400 and 800 ng/mL) significantly inhibited rat ASMCs proliferation at 48 h, and 50–800 ng/mL S100A9 (50, 100, 200, 400, and 800 ng/mL) also induced a lasting effect by significantly inhibiting rat ASMCs proliferation at 72 h in a dose-dependent manner. …”
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Phα1β interaction with the Kv11.1 potassium channel in HEK293 cells transfected with the human ERG channel by João B. Calixto, Adara Aurea dos Santos, Juliano Ferreira, Alessandra Hubner Souza, Célio José de Castro Junior, Marcus Vinicius Gomez

“…Phα1β inhibits high-voltage calcium channels and acts as an antagonist of the TRPA1 receptor, both of which play crucial roles in pain transduction pathways. …”
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Nutritional and anti-nutritional evaluation of injera made from Sorghum, Rice, Teff, and Flaxseed flours using D-optimal mixture design by Moges Amtataw, Estifanos Kassahun, Solomon Tibebu, Tadele Andargie, Takele Ayanaw, Agimassie Agazie, Mesfin Wogayehu, Abebaw Teshome, Sadik Jemal, Deginet Teferi

“…This blend resulted in Injera containing 3.02% fiber, 9.30% protein, 83.16% carbohydrate, 393.24 kcal/100 g energy, 13.99 mg/100 g iron, 4.06 mg/100 g calcium, and 3.78 mg/100 g zinc. The optimization process identified this blend as optimal for improving the nutritional quality of Injera. …”
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Generation of INS-jGCaMP7f knock-in Ca2+ reporter human embryonic stem cell line, GZLe001-C, using CRISPR/Cas9-based gene targeting by Xin Liu, Feng Zhang, Deqi Chen, Jiaxiang Yin, Zirong Bi, Lihua Chen, Jiawei Yan, Qifei Dong, Wei Peng, Tao Xu, Yanying Guo, Haopeng Lin, Huisheng Liu

“…As a member of the single-fluorophore genetically encoded calcium indicators (GECIs), jGCaMP7f is widely applied to investigate intracellular Ca2+ concentrations. …”
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Technosols constructed from urban waste enhance carbon stabilization through improved soil aggregation by Thalita Fernanda Abbruzzini, Blanca Lucia Prado Pano, Lucy Mora Palomino, Alan Ulises Loredo-Jasso, María del Pilar Ortega Larrocea, Ceres Perez Vargas, Victor Manuel Peña Ramirez

“…While C levels remained stable in all technosols, TN decreased in CwO, increasing its C/N ratio to 27, indicating potential N immobilization. Calcium concentrations increased across all technosols (CwO = WCB > EwO), while Na levels decreased, improving aggregate stability. …”
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System- and fish-size-specific reference intervals for plasma analytes in Atlantic salmon (Salmo salar L.) reared in commercial fresh- and saltwater recirculating aquaculture syste... by Thomas Amlie, David Persson, Simen Foyn Nørstebø, Asgeir Østvik, Marit Stormoen, Øystein Evensen

“…Biochemical analyses included sodium, chloride, potassium, osmolality, calcium, magnesium, total protein, albumin, and globulin. …”
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The Effect of A2E on the Ca2+-PKC Signaling Pathway in Human RPE Cells Exposed to Blue Light by Maomei Luo, Shu Wang, Yun Tang, Chun Zeng, Shanjun Cai

“…In a model of blue light-induced damage in N-retinylidene-N-retinylethanolamine (A2E)-loaded human retinal pigment epithelial (RPE) cells, we examined the effect of A2E on the calcium (Ca2+)-protein kinase C (PKC) signaling pathway. …”
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A comprehensive review of probiotics and human health-current prospective and applications by Bhutada Sarita, Dahikar Samadhan, Md Zakir Hassan, Md Zakir Hassan, Elena G. Kovaleva

“…Natural encapsulating materials including sodium alginate, calcium chloride, gel beads and polysaccharide promoting safeguards in probiotics during the digestive process. …”
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Development of bone-mimicking resin for 3D printing with enhanced mechanical properties using ceramic filler by Wei-Chun Lin, Chia-Cheng Cheng, Jui-Fu Tang, Kuan-Chung Huang, Kevin Chiou, Ying-Ruei Liu, Yu-An Chen, Zhi-Xian Wu, Yu-Hsien Chu, Yu-Chun Huang, Wei-Chih Chen

“…Two ceramic particles—aluminum oxide and calcium carbonate—are mixed with the photosensitive resin before polymerization. …”
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Lipidic folding pathway of α-Synuclein via a toxic oligomer by Vrinda Sant, Dirk Matthes, Hisham Mazal, Leif Antonschmidt, Franz Wieser, Kumar T. Movellan, Kai Xue, Evgeny Nimerovsky, Marianna Stampolaki, Magdeline Nathan, Dietmar Riedel, Stefan Becker, Vahid Sandoghdar, Bert L. de Groot, Christian Griesinger, Loren B. Andreas

“…Consistent with reports of anti-parallel β-strands being a defining feature of toxic αS pre-fibrillar intermediates, I1 impacts viability of neuroblasts and disrupts cell membranes, resulting in an increased calcium influx. Our results integrate the occurrence of anti-parallel β-strands as salient features of toxic oligomers with their significant role in the amyloid fibril assembly pathway. …”
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Effect of Different Anti-hypertensive Drugs on Circadian Blood Pressure Profile in Elderly Hypertensive Patients by Bingqing YU, Jinping ZHOU, Zhongxian FENG, Junxia XU

“…According to the survey of drug use, 204 elderly hypertension patients who were treated in cadre's wards of Fuzhou General Hospital were divided into five groups: 1) long-acting calcium channel blockers (CCB group)(<italic>n</italic>=50);2) angiotensin converting enzyme inhibitors (ACEIs) or angiotensinⅡreceptor blockers (ARBs)(AA group)(<italic>n</italic>=22);3) treated with joint anti-hypertensive scheme including ACEIs or ARBs (but not including diuretics)(AAND group)(<italic>n</italic>=60);4) treated with joint anti-hypertensive scheme including diuretics (but not including ACEIs or ARBs)(DNAA group)(<italic>n</italic>=19);5) treated with joint anti-hypertensive scheme including diuretics and ACEIs or ARBs group (DAA group)(<italic>n</italic>=53), to observe the profile on circadian blood pressure in each group, binary <italic>Logistic</italic> regression analysis was used to evaluate the correlation between circadian blood pressure profile and its influencing factors.Results:Compared to the CCB group, the level of all day average SBP and daytime SBP in the DAA group were both lower (all <italic>P</italic>&lt;0.01), the decreasing level of SBP at night in the DAA group was higher (<italic>P</italic>&lt;0.05). …”
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Electrical Stimulation Promotes Cardiac Differentiation of Human Induced Pluripotent Stem Cells by Damián Hernández, Rodney Millard, Priyadharshini Sivakumaran, Raymond C. B. Wong, Duncan E. Crombie, Alex W. Hewitt, Helena Liang, Sandy S. C. Hung, Alice Pébay, Robert K. Shepherd, Gregory J. Dusting, Shiang Y. Lim

“…Beating EBs were also shown to cycle calcium and were responsive to the chronotropic agents, isoproterenol and carbamylcholine, in a concentration-dependent manner. …”
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Using benthos a bioindicator to assess the efficiency constructed wetland community wastewater treatment system by K. Seethong, K. Chunkao, N. Dampin, W. Wararam

“…Soil samples were taken before and during planting at 2-week intervals, evaluating organic matter, pH, electrical conductivity, salinity, phosphorus, potassium, calcium, magnesium, and plant growth indicators. Benthos sampling involved polyvinyl chloride pipe cores at a depth of 5 cm from the soil surface. …”
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