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1761
Capecitabine-induced Hand-foot Syndrome with Hyperpigmentation on Oral Mucosa and Nails: A Rare Entity
Published 2025-02-01“…Case 1 A 28-year-old female, previously diagnosed with stage 4 left-sided inflammatory breast cancer, along with metastases to the right breast and skeletal sites one year ago, as confirmed by trucut biopsy and Positron Emission Tomography scan (PET), presented to our clinic with complaints of fatigue and generalised weakness persisting for the last month. …”
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1762
Loss of correlated proteasomal subunit expression selectively promotes the 20SHigh state which underlies luminal breast tumorigenicity
Published 2025-01-01“…By integrating the gene coexpression signatures of proteasomal subunits in breast cancer (BrCa) patient tissues with the atomistic details of 26S holocomplex, we find that the transcriptional deregulation induced-stoichiometric imbalances perpetuate with disease severity. …”
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1763
ErbB- and MUC1-targeted CAR-T cell immunotherapy of oral squamous cell carcinoma
Published 2023-03-01“…Currently, there are few clinical trials investigating the use of CAR-T cells in HNSCC/OSCC; however, results from trials investigating similar solid tumours, such as breast cancer, can be adopted to help evaluate the use of CAR-T in this cancer. …”
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1764
Clinical, Radiological and Pathological evaluation of breast lumps: a crosssectional study from a tertiary care hospital of north-east India
Published 2025-02-01“…Differentiating these lesions accurately is critical for timely diagnosis and treatment, especially in resource-limited settings. In India, breast cancer remains the most common cancer among women, with variable presentations. …”
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1765
Cancer Mortality by Ethnicity in Colombia Between 2011 and 2022: A Population-Based Study
Published 2025-02-01“…Compared to the Mestizo population, Raizales and Afro-Colombians experienced disproportionately higher age-standardized mortality rates due to prostate cancer (26.6/100,000 and 8.6/100,000 vs. 8.1/100,000), and for Raizales and Rom breast cancer (14.0/100,000 and 103.2/100,000 vs. 9.1/100,000).ConclusionThe disparities in cancer mortality in ethnic minorities in Colombia call for investigating cancer etiology and access to care among the Rom and the Raizal populations.…”
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1766
Purine-rich element binding protein alpha: a DNA/RNA binding protein with multiple roles in cancers
Published 2025-01-01“…Most recently, several studies have revealed that PURα is dysregulated in multiple cancers, such as breast cancer (BC) and esophageal squamous cell carcinoma (ESCC). …”
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1767
Extraction efficiency and bioactive evaluation of Tamarix nilotica and Arthrocnemum macrostachyum extracts for anti-cancer potential.
Published 2025-01-01“…Results suggest that: 1) MAE is more efficient than maceration in recovering metabolites from plant biomass based on measurements of total phenolic content, radical scavenging activity, and bioactivity of extracts based on in vitro cytotoxicity. 2) Only T. nilotica extracts were found to be bioactive based on cytotoxicity measurements. 3) Cancer cell lines displayed differential sensitivity to T. nilotica crude extracts, with breast cancer cells being the most sensitive and lung cancer cells being the least sensitive. 4) Solid-phase fractionation of T. nilotica crude extract using different percentages of methanol resulted in several fractions that were 100-fold more cytotoxic compared to the crude unfractionated extract. …”
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1768
Sulfoxidation of pyrimidine thioate derivatives and study their biological activities
Published 2025-01-01“…Notably, compounds 10 and 12 displayed promising anti-tumor effects, with compound 12 demonstrating superior efficacy against the MCF-7 breast cancer cell line compared to compound 10. The study revealed a spectrum of biological activities across the synthesized derivatives, with modifications often resulting in diminished bioactivity compared to the parent compound 1. …”
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1769
Sub-Tenon Injections of Triamcinolone Acetonide Had Limited Effect on Cystoid Macular Edema Secondary to Nanoparticle Albumin-Bound-Paclitaxel (Abraxane)
Published 2015-01-01“…A 39-year-old Japanese woman with breast cancer presents with decreased vision in both eyes while receiving nab-paclitaxel. …”
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1770
Therapeutic Potential of Acanthospermum hispidum: A Comprehensive Analysis of Its Antimicrobial, Antioxidant, and Anticancer Properties
Published 2024-01-01“…Cytotoxicity assay was performed against human breast cancer cell line MCF7 using the MTT assay. Bioactive compounds were identified using GC-MS. …”
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1771
Effect of Preventive Hormonal Therapy on Breast Density: A Systematic Qualitative Review
Published 2014-01-01“…Breast density (BD) is recognized as one of the strongest independent risk factors of breast cancer (BC). Unlike most other risk factors, BD can be modified, suggesting that it may be a biomarker for preventive interventions. …”
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1772
Assessment of Antioxidant and Cytotoxicity Activities of Saponin and Crude Extracts of Chlorophytum borivilianum
Published 2013-01-01“…Cytotoxicity evaluation of crude extract and total saponin fraction against MCF-7, PC3, and HCT-116 cancer cell lines using 3-(4,5-dimethylthiazol-2-yl)-2,5 diphenyltetrazolium bromide (MTT) cell viability assay indicated a higher cytotoxicity activity of the crude extract than the total saponin fraction on all cell lines, being most effective and selective on MCF-7 human breast cancer cell line.…”
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1773
Cardamom extract alleviates tamoxifen-induced liver damage by suppressing inflammation and pyroptosis pathway
Published 2025-02-01“…Abstract Tamoxifen (TAM) is extensively used to manage estrogen receptor-positive breast cancer. Despite its effectiveness, its administration can negatively impact various organs, including the liver. …”
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1774
DVGEDR: a drug repositioning method based on dual-view fusion and graph enhancement mechanism in heterogeneous networks
Published 2024-12-01“…In case study, DVGEDR identifies 10 new candidate drugs for breast cancer and COVID-19, demonstrating not only superior performance in experimental settings but also potential therapeutic advantages in clinical environments. …”
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1775
Cerebellar re-irradiation after whole brain radiotherapy significant symptom relief with minimal toxicity in metastatic brain patients
Published 2025-02-01“…The cohort’s median age was 53 years, with breast cancer being the most prevalent histology (71%). …”
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1776
FOTELP-VOX 2024: Comprehensive overview of its capabilities and applications
Published 2024-01-01“…This study presents the application of FOTELP-VOX in simulating absorbed dose distributions in various clinical scenarios, including radiotherapy treatment planning for salivary gland tumors, eye melanoma and breast cancer. The results demonstrate the program's capability to replicate complex dose distributions with high accuracy, in comparison with clinical techniques like volumetric modulated arc therapy and 3-D conformal radiotherapy. …”
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1777
A Nonpalpable Nodule in Ectopic Axillary Breast Tissue: Consider Phyllodes Tumor
Published 2016-01-01“…Benign and malignant pathology can develop in ectopic axillary breast tissue, such as fibroadenomas, phyllodes tumors, and breast cancer. We present a rare case of an asymptomatic 43-year-old woman with an axillary nodule which was identified during screening mammography within ectopic axillary breast tissue, initially considered as a suspicious lymph node. …”
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1778
The diagnostic and prognostic significance of HOXC13-AS and its molecular regulatory mechanism in human cancer
Published 2025-02-01“…This review summarizes the clinical significance of HOXC13-AS as a biomarker for human tumor diagnosis and prognosis and outlines the function and molecular regulation mechanism of HOXC13-AS in various types of cancer, including nasopharyngeal carcinoma, breast cancer, oral squamous cell carcinoma, glioma, and cervical cancer. …”
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1779
Fat Grafting With Lymphedema Fat: From Trash to Treasure?
Published 2025-01-01“…This innovative approach addresses breast cancer-related lymphedema and offers potential benefits in regenerative and lymphangiogenic effects without the need for microsurgical expertise. …”
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1780
Microwave Imaging Using CMOS Integrated Circuits with Rotating 4 × 4 Antenna Array on a Breast Phantom
Published 2017-01-01“…A digital breast cancer detection system using 65 nm technology complementary metal oxide semiconductor (CMOS) integrated circuits with rotating 4 × 4 antenna array is presented. …”
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