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1361
Synthesis and Biological Evaluation of New (−)-Gossypol-Derived Schiff Bases and Hydrazones
Published 2017-01-01“…Compound 8a showed the greatest cytotoxic effect against hepatocellular carcinoma (HepG2), lung carcinoma (LU-1), and breast cancer (MCF-7) cell lines with IC50 values of 20.93, 13.58, and 9.40 μM, respectively. …”
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1362
Oral Cancer Awareness and Knowledge in the City of Valongo, Portugal
Published 2012-01-01“…The cancer that most subjects were aware of was breast cancer (99%). Oral cancer was the least mentioned cancer (68.6%). …”
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1363
Bridging the Gap: Interventions to Increase Cancer Screening Adherence in Individuals with Mental Disorders—A Systematic Review
Published 2025-01-01“…Two studies evaluated all three cancer screening programs, two studies evaluated breast cancer screenings, and two studies evaluated colorectal cancer screenings. …”
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1364
Spore-Derived Isolates from a Single Basidiocarp of Bioluminescent <i>Omphalotus olivascens</i> Reveal Multifaceted Phenotypic and Physiological Variations
Published 2025-01-01“…This same subset produced an anticancer agent that was highly potent against MDA-MB-468 breast cancer tumor cells. We interpret these variations in haploids as significant in altering <i>Omphalotus</i> physiology and its production of secondary metabolites, which may in turn alter their ecology and life cycle, and could be further applied to studying fungal physiologies and facilitate linking them to their genetic underpinnings.…”
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1365
Risk of second primary malignancies among survivors of cutaneous melanoma: A nationwide population-based study in the Republic of Korea
Published 2025-01-01“…Additionally, specific SPMs were more common among melanoma survivors, including nonmelanoma skin cancer, oral cavity and pharyngeal cancer, renal cancer, female breast cancer, lung cancer, pancreatic cancer, and liver cancer. …”
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1366
Anticancer, Antioxidant, Antimicrobial Activities, and HPLC Analysis of Alcoholic Extracts of Parthenocissus quinquefolia L. Plant Collected from Çanakkale
Published 2024-03-01“…Herein, fruit and leaf alcoholic extracts of the plant exhibited anticancer activity on triple negative breast cancer (TNBC) cell lines, estrogen receptor positive (ER+) (MCF-7), and human colon adenocarcinoma (HT-29) cancer cell lines. …”
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1367
Pregnancy after Cancer Treatment and Pregnancy Associated Cancer: A Single Center Experience with 96 Cases
Published 2015-08-01“…The most common type of cancer was the breast cancer in 25 patients, followed by thyroid, leukemia, osteosarcoma, lymphoma and ovarian cancer. …”
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1368
Everolimus Implicated in Case of Severe Gastrointestinal Hemorrhage
Published 2017-01-01“…Breast cancer remains the leading cause of cancer and the third leading cause of cancer related deaths among our population with an estimated number of 246,660 new cases and 40,450 deaths in 2016. …”
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1369
GC-MS Profiling and Therapeutic Potentials of Prosopis juliflora (Sw.) DC: Cytotoxic and Antimicrobial Insights
Published 2024-01-01“…Cytotoxic activity was seen in human breast cancer (MCF-7), human ovary adenocarcinoma (A2780), and human colon adenocarcinoma (HT-29) cell lines, as well as in normal human fetal lung fibroblasts (MRC-5), when subjected to the MTT assay. …”
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1370
A review on intrathecal administration of medications for leptomeningeal metastases in solid tumors
Published 2025-02-01“…It can occur in various types of cancers, with lung and breast cancer being the most frequently associated. The treatment approach for LMD includes a combination of supportive care, surgery, chemotherapy, radiotherapy, targeted therapy, immunotherapy, and intrathecal (IT) therapy, among other modalities. …”
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1371
Isolation and Bioactivity of Natural Products from <i>Streptomyces</i> sp. MA37
Published 2025-01-01“…We also demonstrate that legonoxamine A possesses potent anticancer activity (IC<sub>50</sub> = 2.2 µM), exhibiting a remarkable ~30-fold increase in potency against MCF-7 ATCC HTB-22 breast cancer cells compared to desferrioxamine B, a structural analogue of legonoxamine A (IC<sub>50</sub> = 61.1 µM). …”
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1372
Actin-Binding Proteins as Potential Biomarkers for Chronic Inflammation-Induced Cancer Diagnosis and Therapy
Published 2021-01-01“…This is the case for breast cancer, gastric cancer, lung cancer, prostate cancer, liver cancer, esophageal cancer, pancreatic cancer, melanoma, and colorectal cancer. …”
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1373
A Rare Case of Large-Vessel Vasculitis following Checkpoint Inhibitor Therapy and Pegfilgrastim
Published 2022-01-01“…We present a 59-year-old female with left stage IIA (cT2N0M0) triple-negative breast cancer receiving neoadjuvant decitabine and pembrolizumab prior to neoadjuvant chemotherapy (NAC). …”
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1374
Synthesis, DNA-Binding, Anticancer Evaluation, and Molecular Docking Studies of Bishomoleptic and Trisheteroleptic Ru-Diimine Complexes Bearing 2-(2-Pyridyl)-quinoxaline
Published 2021-01-01“…MTT experiments revealed that both complexes induce apoptosis of MCF-7 (breast cancer) cells in low concentrations. Confocal microscopy indicated that 2 localizes in the nucleus and internalizes more efficiently in MCF-7 than in HEK-293.…”
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1375
Risk of recurrence and bleeding in patients with cancer‐associated venous thromboembolism treated with rivaroxaban: A nationwide cohort study
Published 2019-03-01“…At 6 months, recurrent VTE occurred in 6.1% (15.1 events per 100 person‐years) with the highest absolute risks for genitourinary cancer (8.1%), gastrointestinal cancer (7.3%), and breast cancer (6.5%). Major bleeding occurred in 1.9% (5.3 events per 100 person‐years), in particular, in genitourinary cancer (4.5%) and lung cancer (4.2%). …”
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1376
Synthesis of Phthalimide Imine Derivatives as a Potential Anticancer Agent
Published 2020-01-01“…On the other hand, the halogenated H6 Schiff base structure was successful in securing effective cancer inhibition to both colon and breast cancer cell lines, while maintaining selective action toward normal tissues. …”
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1377
Nano-Azo Ligand and Its Superhydrophobic Complexes: Synthesis, Characterization, DFT, Contact Angle, Molecular Docking, and Antimicrobial Studies
Published 2020-01-01“…The binding between H2L and its Cd(II) complex with receptors of the crystal structure of S. aureus (PDB ID: 3Q8U), crystal structure of protein phosphatase (PPZ1) of Candida albicans (PDB ID: 5JPE), receptors of breast cancer mutant oxidoreductase (PDB ID: 3HB5), and crystal structure of Escherichia coli (PDB ID: 3T88) was predicted and given in detail using molecular docking.…”
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1378
Synthesis, Characterization, Anticancer, and Antioxidant Studies of Ru(III) Complexes of Monobasic Tridentate Schiff Bases
Published 2016-01-01“…In vitro anticancer studies of the synthesized complexes against renal cancer cells (TK-10), melanoma cancer cells (UACC-62), and breast cancer cells (MCF-7) was investigated using the Sulforhodamine B assay. …”
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1379
Real-world clinical multi-omics analyses reveal bifurcation of ER-independent and ER-dependent drug resistance to CDK4/6 inhibitors
Published 2025-01-01“…Abstract To better understand drug resistance mechanisms to CDK4/6 inhibitors and inform precision medicine, we analyze real-world multi-omics data from 400 HR+/HER2- metastatic breast cancer patients treated with CDK4/6 inhibitors plus endocrine therapies, including 200 pre-treatment and 227 post-progression samples. …”
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1380
Can a physical activity program improve functional capacity and fatigue in people with cancer? A retrospective analysis
Published 2025-02-01“…Results Among the 264 participants (age 57.36 ± 12.43 years; 189 women; 134 with breast cancer), 125 (47%) completed the program. Walking capacity (+ 41.63 ± 91.00 m) and fatigue (-2.01 ± 3.77) were improved after the program (p < 0.001). …”
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