A mathematical model of stem cell regeneration with epigenetic state transitions by Qiaojun Situ, Jinzhi Lei

“…As an example, we apply the model to study the dynamics of state transition in breast cancer stem cells.…”
Get full text

Multiple Myeloma Breast Involvement: A Case Report by Heba O. E. Ali, Zafar Nasir, Ahmed M. S. M. Marzouk

“…The patient was managed for multiple spinal lesions that were primarily thought to be metastasis from primary breast cancer.…”
Get full text

Subepithelial Corneal Deposits Associated with Exemestane by Annahita Amireskandari, Elena Nguyen, David Hinkle, Thomas Mauger

“…This is a case report of corneal deposits noted in a 69-year-old female patient taking the aromatase inhibitor, exemestane, after undergoing a mastectomy and chemotherapy for breast cancer. The patient presented to our eye clinic for a new-onset floater in one eye, and bilateral subepithelial opacities were found incidentally on exam. …”
Get full text

Immune Checkpoint Inhibitor Therapy for Bone Metastases: Specific Microenvironment and Current Situation by Chang Liu, Miao Wang, Changli Xu, Bo Li, Juxiang Chen, Jianchun Chen, Zhiwei Wang

“…On this basis, we expounded the clinical application of immune checkpoint inhibitors for bone metastasis of common tumors, including non-small-cell lung cancer, renal cell carcinoma, prostate cancer, melanoma, and breast cancer. Then, the deficiencies and limitations in current researches were summarized. …”
Get full text

Molecular Alterations of KIT Oncogene in Gliomas by Ana L. Gomes, Jorge S. Reis-Filho, José M. Lopes, Olga Martinho, Maryou B. K. Lambros, Albino Martins, Fernando Schmitt, Fernando Pardal, Rui M. Reis

Get full text

Evaluating pre-processing and deep learning methods in medical imaging: Combined effectiveness across multiple modalities by Thien B. Nguyen-Tat, Tran Quang Hung, Pham Tien Nam, Vuong M. Ngo

“…These datasets include two X-ray collections: the COVID-19 Pneumonia Normal Chest PA Dataset and the Osteoporosis Knee X-ray Dataset; two CT scan datasets: the Chest CT-Scan Images Dataset and the Brain Stroke CT Image Dataset; two MRI datasets: the Breast Cancer Patients MRI and the Brain Tumor MRI Dataset; and two ultrasound datasets: the Ultrasound Breast Images for Breast Cancer and the MT Small Dataset. …”
Get full text

A Threshold Technique Study to Understand Patient Preference for Smooth Versus Textured Breast Implants by Dallas Wood, PhD, Peyton N. Williams, MPH, Jessica E. Thompson, PhD, Susana Peinado, PhD, Avery A. Tilley, MS, David Gebben, PhD, Jacqueline M. Major, PhD, Jessica P. Weinberg, MPP, Sung W. Yoon, MD, Michelle E. Tarver, MD, PhD

“…We fielded a threshold technique survey to 405 respondents from 4 cohorts: (1) patients with breast cancer who were considering but did not receive reconstruction with implants, (2) patients with breast cancer who had received reconstruction with implants, (3) persons considering breast augmentation with implants, and (4) patients who had received breast augmentation with implants. …”
Get full text

Dynamin-1 is a potential mediator in cancer-related cognitive impairment by Ding Quan Ng, Casey Hudson, Tracy Nguyen, Sukesh Kumar Gupta, Yong Qin Koh, Munjal M. Acharya, Alexandre Chan

“…Following that, a syngeneic young-adult WT (C57BL/6) female mouse model of breast cancer chemobrain was developed to study DNM1 expression in the hippocampus. …”
Get full text

Individualized resting-state functional connectivity abnormalities unveil two major depressive disorder subtypes with contrasting abnormal patterns of abnormality by Keke Fang, Lianjie Niu, Baohong Wen, Liang Liu, Ya Tian, Huiting Yang, Ying Hou, Shaoqiang Han, Xianfu Sun, Wenzhou Zhang

Get full text

Women's Health Crisis in Pakistan by Zafar Mirza

“…Women also face a heightened risk of communicable and non-communicable diseases, including the highest breast cancer rate in Asia. Economic factors, such as low workforce participation and wage gaps, further exacerbate these challenges. …”
Get full text

A Case Report on Ductal Carcinoma in situ Arising from Axillary Accessory Breast Tissue by Kyung Eun Lee, Juhee Kang, Woo Young Kang, Ok Hee Woo

“…Malignancies arising in accessory breast tissue are rare, representing approximately 0.3%–0.6% of all breast cancer cases. When evaluating accessory breasts, it is essential to apply the same management strategies used for conventionally positioned breasts. …”
Get full text

Genetic factors for breast carcinogenesis by Pedro Enrique Miguel-Soca, Ivis Argüelles González, Marisol Peña González

“…Breast cancer is a multifactorial genenetic disease in which oncogenes derived from normal cellular genes intervene, which constitute positive signals of cellular proliferation and tumour suppressor genes and represent negative signals of cells multiplication and differentiation. …”
Get full text

Revisiting Estrogen: Efficacy and Safety for Postmenopausal Bone Health by Sandra M. Sacco, Wendy E. Ward

“…While hormone therapy (HT) is an effective means to re-establish endogenous estrogen levels and reduce the risk of future fracture, its use can be accompanied by undesirable side effects such as stroke and breast cancer. In this paper, we revisit the issue of whether HT can be both safe and effective for the prevention of postmenopausal bone loss by examining standard and alternative doses and formulations of HT. …”
Get full text

Dysphagia and Neck Swelling in a Case of Undiagnosed Lhermitte-Duclos Disease and Cowden Syndrome by Zishuo Ian Hu, Lev Bangiyev, Roberta J. Seidman, Jules A. Cohen

“…This case illustrates the importance of the overlap between LDD, Cowden syndrome, thyroid disease, and breast cancer.…”
Get full text

Diabetic Mastopathy as a Radiographically Occult Palpable Breast Mass by Uma Thanarajasingam, Beiyun Chen, Cindy L. Tortorelli, James W. Jakub, Karthik Ghosh

“…Diabetic mastopathy is an uncommon, benign disease of the breast that can occur in women with diabetes and clinically mimic breast cancer. We describe a patient with long-standing type 1 diabetes who presented with a palpable breast mass with negative imaging findings on mammography, ultrasonography, and breast MRI. …”
Get full text

Wings for life in the Guamuhaya Butterflies: the importance of a project by Eneida Bravo Polanco, Asleny Sánchez Leandro

“…During 2020, 3,887 people in Cuba were diagnosed with breast cancer, which represents a rate of 39.6, and 1,714 died, for a rate of 30.4. …”
Get full text

Bilateral De Quervain Syndrome after Aromatase Inhibitor Administration: A Case Report and Review of the Literature by Konstantinos Papadimitriou, Panteleimon Kountourakis, Emmanouil Morakis, Vassilios Vassiliou, Vasileios Barbounis, Alexandros Ardavanis

“…Aromatase inhibitors are widely used as one of the main treatment options of both early and advanced hormone receptor-positive breast cancer in postmenopausal women. Unfortunately, musculoskeletal symptoms are often presented in patients treated with aromatase inhibitors (AIs), and, although the pathogenesis is unknown, postulated mechanisms have been described. …”
Get full text

A morphometric signature to identify ductal carcinoma in situ with a low risk of progression by Marcelo Sobral-Leite, Simon P. Castillo, Shiva Vonk, Hendrik A. Messal, Xenia Melillo, Noomie Lam, Brandi de Bruijn, Yeman B. Hagos, Myrna van den Bos, Joyce Sanders, Mathilde Almekinders, Lindy L. Visser, Emma J. Groen, Petra Kristel, Caner Ercan, Leyla Azarang, Jacco van Rheenen, E. Shelley Hwang, Yinyin Yuan, Grand Challenge PRECISION Consortium, Renee Menezes, Esther H. Lips, Jelle Wesseling

“…Abstract Ductal carcinoma in situ (DCIS) may progress to ipsilateral invasive breast cancer (iIBC), but often never will. Because DCIS is treated as early breast cancer, many women with harmless DCIS face overtreatment. …”
Get full text

Blockades of effector T cell senescence and exhaustion synergistically enhance antitumor immunity and immunotherapy by Xia Liu, Emily Shaw, Fusheng Si, Guangyong Peng, Yan Tao, Feiya Ma, David Bagley, Yuanqin Zhang

“…Therefore, a better understanding of the molecular mechanism responsible for T cell senescence in the TME and development of novel strategies to prevent effector T cell senescence are urgently needed for cancer immunotherapy.Methods Senescent T cell populations in the TMEs in mouse lung cancer, breast cancer, and melanoma tumor models were evaluated. …”
Get full text

Human Serum Albumin and Human Serum Albumin Nanoparticles as Carriers of 10-(2′-Pyrimidyl)-3,6-diazaphenothiazine: In Vitro Spectroscopic Studies by Aleksandra Owczarzy, Karolina Kulig, Beata Morak-Młodawska, Małgorzata Jeleń, Tammam Muhammetoglu, Wojciech Rogóż, Małgorzata Maciążek-Jurczyk

“…Due to nontoxicity and biocompatibility, this protein can be used as a nanocarrier. 10-(2′-Pyrimidyl)-3,6-diazaphenothiazine (10-Pyr-3,6-DAPT) is a phenothiazine showing high anticancer potential in vitro against glioma, melanoma and breast cancer cells. Additionally, this compound is characterized by selectivity of action towards MCF-7 breast cancer and has low cytotoxicity towards normal cells. …”
Get full text