Implementing a nurse-enabled, integrated, shared-care model involving specialists and general practitioners in early breast cancer post-treatment follow-up (EMINENT): a single-centre, open-label, phase 2, parallel-group, pilot, randomised, controlled trialResearch in context by Raymond J. Chan, Fiona Crawford-Williams, Chad Yixian Han, Lee Jones, Alexandre Chan, Daniel McKavanagh, Marissa Ryan, Christine Carrington, Rebecca L. Packer, Megan Crichton, Nicolas H. Hart, Emma McKinnell, Melissa Gosper, Juanita Ryan, Bethany Crowe, Ria Joseph, Carolyn Ee, Jane Lee, Steven M. McPhail, Katharine Cuff, Laisa Teleni, Jon Emery

Subjects: “…Breast cancer…”
Get full text

Multiomics analysis reveals the involvement of NET1 in tumour immune regulation and malignant progression by Jian Pang, Xiaoyan Huang, Ya Gao, Xinyu Guan, Lejia Xiong, Lun Li, Nana Yin, Mei Dai, Tong Han, Wenjun Yi

Subjects: Get full text

Ly6E on tumor cells impairs anti-tumor T-cell responses: a novel mechanism of tumor-induced immune exclusion by Lan Hailin, Chen Yiting, Wu Yue, Li Lijun, Zhang Renlu, Chen Yunhan, Zhu Yanyang, Zhang Qiuyu

Subjects: Get full text

Genome-wide association studies are enriched for interacting genes by Peter T. Nguyen, Simon G. Coetzee, Irina Silacheva, Dennis J. Hazelett

Subjects: Get full text

In vitro antitumor effects of methanolic extracts of three Ganoderema mushrooms by Elshahat A. Toson, Amira A. El-Fallal, Marwa A. Oransa, Hoda M. El-Gharabawy

Subjects: Get full text

Fluorescence Lifetime Imaging for Quantification of Targeted Drug Delivery in Varying Tumor Microenvironments by Amit Verma, Vikas Pandey, Catherine Sherry, Taylor Humphrey, Christopher James, Kailie Matteson, Jason T. Smith, Alena Rudkouskaya, Xavier Intes, Margarida Barroso

Subjects: “…breast tumor…”
Get full text

HEalth-Related Quality of Life-Intervention in Survivors of Breast and Other Cancers Experiencing Cancer-Related Fatigue and Associated Cognitive Symptoms Using TraditionAL Chinese Medicine: The ‘HERBAL’ Trial by Alexandre Chan PharmD, Daniella Chan BS, Ding Quan Ng BSPharm, Huang Fang Zheng MD, Quan Ming Tan MCM, Chia Jie Tan PhD, Jolene Hui Min Toh BS, Ning Yi Yap PhD, Yi Long Toh PhD, Yu Ke PhD, Edmund Chun Ann Wang BS, Queenie Pei Ni Lim BSocSc, Han Kiat Ho PhD, Lita Chew MMS, Tira J. Tan MBBS

“…Both groups were predominantly Chinese (93% vs 62%), breast cancer patients (87% vs 62%), and diagnosed with stage 2 cancer (60% vs 46%). …”
Get full text

Comparison of Characteristics of Breast Cancer Detected through Different Imaging Modalities in a Large Cohort of Hong Kong Chinese Women: Implication of Imaging Choice on Upcoming Local Screening Program by Yik Shuen Chan, Wai Ka Hung, Lok Wa Yuen, Ho Yan Yolanda Chan, Chiu Wing Winnie Chu, Polly Suk Yee Cheung

“…The Breast Journal…”
Get full text

Clinical Features and Prognosis Analysis of Hormone Receptor-Positive, HER2-Negative Breast Cancer with Differential Expression Levels of Estrogen and Progesterone Receptors: A 10-Year Retrospective Study by Jin Liu, Mingyu Gan, Zijing Lin, Qin Deng, Juan Deng, Bin Zeng, Yanling Shi, Jia Ming

“…The Breast Journal…”
Get full text

Resolution on the results of scientific-practical conference "Clinical evidence of increasing overall survival in the treatment of metastatic breast cancer", held on 29 November 2014 under the auspices of the Department of health of Moscow by E. T. Bairamov, A. V. Belonogov, V. V. Brusnichkina, A. V. Bulakh, M. Y. Byahov, S. N. Gurov, G. G. Eremeev, N. V. Zhukov, L. G. Zhukova, L. M. Kogonia, P. V. Koposov, L. K. Ovchinnikova, V. V. Radlevich, E. A. Samyshina, A. P. Seryakov, M. D. Ter-Ovanesov, I. E. Shumskaya

“…Objectives: discussion of modern treatment options for metastatic breast cancer (MBC), the determining of the optimal treatment for subgroups of patients with poor prognosis.…”
Get full text

A qualitative study to explore healthcare providers' perspectives on barriers and enablers to early detection of breast and cervical cancers among women attending primary healthcare clinics in Johannesburg, South Africa. by Gugulethu Tshabalala, Charmaine Blanchard, Keletso Mmoledi, Desiree Malope, Daniel S O'Neil, Shane A Norris, Maureen Joffe, Janan Janine Dietrich

“…We explored contextual enablers and barriers for early detection of breast and cervical cancers according to facility managers and clinical staff at primary healthcare clinics in the Soweto neighbourhood of Johannesburg, South Africa. …”
Get full text

Correction: miR-630 targets IGF1R to regulate response to HER-targeting drugs and overall cancer cell progression in HER2 over-expressing breast cancer by Claire Corcoran, Sweta Rani, Susan Breslin, Martina Gogarty, Irene M Ghobrial, John Crown, Lorraine O’Driscoll

Get full text

Influence of diet nutrient density and a multicarbohydrase containing α-galactosidase on performance, carcass characteristics, breast myopathies, and nutrient utilization of broilers reared from 1 to 42 days of age by J.P. Gulizia, J.I. Vargas, S.M. Bonilla, J.R. Hernandez, L.M. Almeida, P. Soster, S. Thuekeaw, B. Hutson, S. Llamas-Moya, T. Duong, W.J. Pacheco

“…Broiler performance (d 14, 28, and 42), processing yields (d 43), breast myopathies (d 43), apparent ileal nutrient digestibility (d 42), and digestible nutrient intake (d 29 to 42) were determined. …”
Get full text

Neoadjuvant pyrotinib and trastuzumab in HER2-positive breast cancer with no early response (NeoPaTHer): efficacy, safety and biomarker analysis of a prospective, multicentre, response-adapted study by Fei Wang, Yongjiu Wang, Bin Xiong, Zhenlin Yang, Jingfen Wang, Yumin Yao, Lixiang Yu, Qinye Fu, Liang Li, Qiang Zhang, Chao Zheng, Shuya Huang, Liyuan Liu, Chun Liu, Huaibo Sun, Beibei Mao, Dong-Xu Liu, Zhigang Yu

“…Abstract The potential benefits of pyrotinib for patients with trastuzumab-insensitive, HER2-positive early-stage breast cancer remain unclear. This prospective, multicentre, response-adapted study evaluated the efficacy and safety of adding pyrotinib to the neoadjuvant treatment of HER2-positive breast cancer patients with a poor response to initial docetaxel plus carboplatin and trastuzumab (TCbH). …”
Get full text

Cell Counts, rather than Proportion, of CD8/PD-1 Tumor-Infiltrating Lymphocytes in a Tumor Microenvironment Associated with Pathological Characteristics of Chinese Invasive Ductal Breast Cancer by Qingkun Song, Feng Shi, Maya Adair, Hong Chang, Xiudong Guan, Yanjie Zhao, Yuchen Li, Guangjiang Wu, Jiangping Wu

“…Methods. 133 patients diagnosed with primary invasive ductal breast cancer were recruited into the cross-sectional study consecutively. …”
Get full text

Study protocol of a pilot randomised controlled trial assessing the feasibility and acceptability of RecoverEsupport: a digital health intervention to enhance recovery in women undergoing surgery for breast cancer by Christopher Oldmeadow, Mitch J Duncan, Penny Reeves, Priscilla Viana da Silva, Rebecca Wyse, Helen Moore, Alison Zucca, Sancha Robinson, Stephen Ridley Smith, Emma Sansalone, Owen Morris, Rebecca Chenery, Lara Riley, Anna Palazzi-Parsons

“…Introduction Internationally, breast cancer is the second most diagnosed cancer with approximately 2.3 million people diagnosed each year. 40% will require a mastectomy which has an average length of hospital stay of 1–2 days. …”
Get full text

Reduction on Proinflammatory Cytokines after Application of Transcutaneous Electrical Nerve Stimulation (TENS) in Patients with a Breast Cancer: A Nonrandomized, Open, and Single-Arm Study Protocol with Paired Analysis by Tábata Cristina do Carmo Almeida, Simone Meneghette Zatta, Laércio da Silva Paiva, Luís Eduardo Werneck de Carvalho, Jean Schoueri, Luiz Carlos de Abreu, Fernando Luiz Affonso Fonseca, Fernando Adami

“…The aim of this study will be to evaluate the effect of TENS on blood reduction of proinflammatory cytokines in breast cancer patients. Methods. This study will evaluate at least 59 patients, over 18 years of age, diagnosed with breast cancer, but who have not yet started any treatment. …”
Get full text

Hypoxic BMSC-derived exosomal miR-210-3p promotes progression of triple-negative breast cancer cells via NFIX-Wnt/β-catenin signaling axis by Meng Wang, Yi Zheng, Qian Hao, Guochao Mao, Zhijun Dai, Zhen Zhai, Shuai Lin, Baobao Liang, Huafeng Kang, Xiaobin Ma

Subjects: “…Triple-negative breast cancer…”
Get full text

Neoadjuvant Endocrine Therapy Compared to Neoadjuvant Chemotherapy in Node-Positive HR+, HER2− Breast Cancer (Nodal pCR and the Rate of ALND): A Systematic Review and Meta-Analysis by Mahtab Vasigh, Mohammadreza Karoobi, Austin D. Williams, Fasika Molla Abreha, Richard J. Bleicher, Seyed Mostafa Meshkati Yazd, Tahereh Shamsi, Ramesh Omranipour, Ahmad Elahi, David Farhat, Mehran Habibi

“…The Breast Journal…”
Get full text

Oncometabolite D-2HG drives tumor metastasis and protumoral macrophage polarization by targeting FTO/m6A/ANGPTL4/integrin axis in triple-negative breast cancer by Siyue Zhang, Ning Zhang, Tong Wan, Yinqiao He, Jie Hao, Yiwei Liu, Yidong Liu, Bing Chen, Wenjing Zhao, Lijuan Wang, Dan Luo, Chao Gao, Qifeng Yang

“…Previous studies have reported the diverse effects of D-2HG in pathophysiological processes, yet its role in breast cancer remains largely unexplored. Methods We applied an advanced biosensor approach to detect the D-2HG levels in breast cancer samples. …”
Get full text