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301
Anti-VEGF therapy improves EGFR-vIII-CAR-T cell delivery and efficacy in syngeneic glioblastoma models in mice
Published 2023-03-01“…We previously showed that blocking vascular endothelial growth factor (VEGF) signaling can normalize tumor vessels in murine and human tumors, including GBM, breast, liver, and rectal carcinomas. Moreover, we demonstrated that vascular normalization can improve the delivery of CD8+ T cells and the efficacy of immunotherapy in breast cancer models in mice. …”
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302
Dysbiosis and extraintestinal cancers
Published 2025-02-01“…This review aims to comprehensively summarize the existing evidence that points to the potential role of dysbiosis in the malignant transformation of extraintestinal organs such as the liver, breast, lung, and pancreas. Additionally, we delve into the limitations inherent in current methodologies, particularly the challenges associated with differentiating low loads gut-derived microbiome within tumors from potential sample contamination or symbiotic microorganisms. …”
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303
Detection of Masses in Mammogram Images Based on the Enhanced RetinaNet Network With INbreast Dataset
Published 2025-02-01“…Until now, analyzing mammogram images is still the main method used by doctors to diagnose and detect breast cancers. However, this process usually depends on the experience of radiologists and is always very time consuming.Patients and Methods: We propose to introduce deep learning technology into the process for the facilitation of computer-aided diagnosis (CAD), and address the challenges of class imbalance, enhance the detection of small masses and multiple targets, and reduce false positives and negatives in mammogram analysis. …”
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304
The PDE4DIP-AKAP9 axis promotes lung cancer growth through modulation of PKA signalling
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305
The current and future cancer burden in the Gulf Cooperation Council (GCC) countries
Published 2024-09-01“…Colorectal (14%) followed by breast cancer (9%) were the leading causes of cancer death, though the magnitude of rates of the major cancer types varied substantially across the GCC countries. …”
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306
Women's Health Crisis in Pakistan
Published 2025-02-01“…Women also face a heightened risk of communicable and non-communicable diseases, including the highest breast cancer rate in Asia. Economic factors, such as low workforce participation and wage gaps, further exacerbate these challenges. …”
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307
Constipation treatment safety at pregnancy
Published 2010-12-01“…Polyethylene glycol-containing laxatives, are safe and recommended as treatment of choice in constipation at pregnant and breast-feeding women. Macrogol-4000 is not metabolized and not absorbed, having therefore no undesirable effect on fetus.Conclusion. …”
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308
Blockades of effector T cell senescence and exhaustion synergistically enhance antitumor immunity and immunotherapy
Published 2022-10-01“…Therefore, a better understanding of the molecular mechanism responsible for T cell senescence in the TME and development of novel strategies to prevent effector T cell senescence are urgently needed for cancer immunotherapy.Methods Senescent T cell populations in the TMEs in mouse lung cancer, breast cancer, and melanoma tumor models were evaluated. …”
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309
Effect of 25-hydroxycholecalciferol and high phytase doses on performance, vitamin D status, bone mineralization, and mechanistic target of rapamycin gene expression of broilers
Published 2025-02-01“…The mRNA expression of mechanistic target of rapamycin in breast muscle assessed at 42 d was enhanced with 2 000 FYT/kg (P < 0.001). …”
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310
Syringoid eccrine carcinoma of the nipple in a male patient with lymph node metastasis: A case report
Published 2024-04-01“…Here we present a rare case of SEC/ syringomatous carcinoma of nipple in a 51-year-old male breast with associated axillary lymph node metastasis. …”
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311
IMPACT OF HYGIENE BATHING AND BREASTFEEDING OF LACTATING MOTHERS ON INFANT MORTALITY IN KATSINA STATE
Published 2024-06-01“…This will educate women to understand the dangers associated with delay, denial, and importance offrequent breast feeding of infant at regular interval. …”
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312
A Rare Case Report: Primary Vulvar Adenocarcinoma of Mammary Gland Type
Published 2025-02-01“…The tumor cells were positive for SOX10, TRPS1, and E-cadherin, and negative for ER, PR, and HER-2/neu, ruling out metastatic breast carcinoma. This case underscores the importance of specific markers like TRPS1 in accurately diagnosing rare vulvar malignancies and guiding effective treatment strategies. …”
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313
Clinical Gynecologic Endocrinology and Infertility /
Published 2011Table of Contents: “…Molecular biology for clinicians -- Hormone biosynthesis, metabolism, and mechanism of action -- The ovary-embryology and development -- The uterus -- Neuroendocrinology -- Regulation of the menstrual cycle -- Sperm and egg transport, fertilization, and implantation -- The endocrinology of pregnancy -- Normal and abnormal sexual development -- Normal and abnormal growth and pubertal development -- Amenorrhea -- Chronic anovulation and the polycystic ovary syndrome -- Hirsutism -- Menstrual disorders -- Abnormal uterine bleeding -- The breast -- Menopause and the perimenopausal transition -- Postmenopausal hormone therapy -- Obesity -- Reproduction and the thyroid -- Family planning, sterilization, and abortion -- Oral contraception -- Vaginal and transdermal estrogen-progestin contraception -- Long-acting methods of contraception -- Intrauterine contraception -- Barrier methods of contraception and withdrawal -- Female infertility -- Recurrent early pregnancy loss -- Endometriosis -- Male infertility -- Induction of ovulation -- Assisted reproductive technologies -- Ectopic pregnancy -- Appendix-I: Interpreting epidemiologic reports -- Appendix-II: Selected laboratory values and the international system of units (SI Units).…”
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314
Long non-coding RNA involved in the carcinogenesis of human female cancer - a comprehensive review
Published 2025-02-01“…This review provides an overview of the various lncRNA entities that influence and regulate the gynaecological cancers, namely, cervical, breast, ovarian and uterine cancers. The review curates a list of the key players and their effect on cellular processes. lncRNA molecules show immense potential to be used as diagnostic and prognostic indicators and in therapeutic strategies. …”
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315
Colorectal cancer spectrum: From subtypes and epidemiology to oncotherapies
Published 2025-04-01“…Colorectal cancer (CRC) has an incidence rate of 10 % and is the third most common cause of mortality worldwide, following breast and lung cancer. The clinical symptoms of CRC appear in the last phases of the disease and there is a substantial golden period between the formation of polyps and the onset of cancer. …”
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316
Neoadjuvant anti-PD-1-based immunotherapy: evolving a new standard of care
Published 2025-01-01“…Groundbreaking regulatory approvals in triple-negative breast cancer, non-small cell lung cancer and melanoma will certainly be followed by additional approvals in other disease indications, as clinical and basic research are burgeoning globally in hundreds of clinical trials across dozens of cancer types. …”
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318
Rat Model of Cystic Neutrophilic Granulomatous Mastitis by Corynebacterium Kroppenstedtii
Published 2025-02-01“…The expression levels of C-reactive protein and interleukin-1 beta were detected.Results: Rats in groups A, D, and E exhibited breast masses with erythema, with some showing ulceration, and granulomatous structures in pathological. …”
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319
Metabolomics, network pharmacology, and microbiome analyses uncover the mechanisms of the Chinese herbal formula for the improvement of meat quality in spent hens
Published 2025-02-01“…Results The results indicated that CHF supplementation improved the meat quality by reducing drip loss (P < 0.05), b* value (P = 0.058), and shear force (P = 0.099) and increasing cooked meat percentage (P = 0.054) and dry matter (P < 0.05) of breast muscle. The addition of CHF improved the nutritional value of breast muscle by increasing (P < 0.05) the content of C18:2n-6, n-6/n-3 polyunsaturated fatty acids (PUFA), total PUFA, PUFA-to-saturated fatty acids (SFA) ratio, and hypocholesterolemic-to-hypercholesterolemic ratio, and tending to increase serine content (P = 0.069). …”
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320
Impact of social support and breastfeeding success on the self-efficacy levels of adolescent mothers during the postpartum period
Published 2025-02-01“…Methods Following ethical approval, The Socio-Demographic Data Form, the Breast Milk and Breastfeeding Information Form, the Multidimensional Scale of Perceived Social Support (MSPSS), the Breastfeeding Self-Efficacy Short Form Scale (BFSES) and the LATCH Breastfeeding Diagnostic and Assessment Scale were used to collect data and the study was completed with 163 participants. …”
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