Development of a TCR-like antibody and chimeric antigen receptor against NY-ESO-1/HLA-A2 for cancer immunotherapy by Xin Liu, Yang Du, Ningyan Zhang, Zhiqiang An, Wei Xiong, Yixiang Xu, Bingnan Yin, Yuqian Huang, Junjun Chu, Changsheng Xing, Chen Qian, Tianhao Duan, Helen Y Wang, John S. Yu, Rongfu Wang

“…In vivo antitumor activity was investigated in a triple-negative breast cancer (TNBC) model and primary melanoma tumor model in immunocompromised mice.Results Monoclonal antibody 2D2 identified from phage-displayed library specifically bound to NY-ESO-1157-165 in the context of human leukocyte antigen HLA-A*02:01 but not to non-A2 or NY-ESO-1 negative cells. …”
Get full text

Longitudinal Changes in Body Weight of Breastfeeding Mothers in the First Year after Delivery and its Relationship with Human Milk Composition: a Combined Longitudinal and Cross-se... by Huijuan Ruan, Yajie Zhang, Qingya Tang, Xuan Zhao, Xuelin Zhao, Yi Xiang, Wei Geng, Yi Feng, Wei Cai

“…Leptin and adiponectin in breast milk and leptin in plasma are associated with the maternal body composition. …”
Get full text

Changes in cancer incidence and stage during the COVID-19 pandemic in 2020–2021 in the Nordic countries by Anna Johansson, Anna Skog, Tom Børge Johannesen, Tor Åge Myklebust, Simon M. Kønig, Charlotte Wessel Skovlund, Lina Steinrud Mørch, Søren Friis, Marnar Fríðheim Kristiansen, David Pettersson, Eva María Gudmundsdóttir, Nanna Margrét Kristinsdóttir, Helgi Birgisson, Sandra Irenaeus, Johan Ahlgren, Mats Lambe, Elli Hirvonen, Janne Pitkäniemi, Giske Ursin

“…Incidence rates also declined in the second pandemic wave (Q1 2021), ranging from –8.6% [–10.2%; –6.9%] (Sweden) to –2.3% [–4.6%; 0.1%] (Norway), and in Sweden also by –3.1% [–4.8%; –1.3%] in the third pandemic wave (Q4 2021). Stage I breast cancer incidence declined during 2020 in Denmark/Norway/Sweden, with some catch-up in stage II incidence in 2021. …”
Get full text

Comparative Study on Growth Characteristics and Early Selection Efficiency of Hybrid Offspring of <i>Populus deltoides</i> ‘DD-109’ and <i>P. maximowiczii</i> in Liaoning, China... by Wei Liu, Chenggong Liu, Yan Zhang, Jinhua Li, Jiabao Ji, Xiaorui Qin, Fenfen Liu, Chengcheng Gao, Nairui Wang, Xueli Zhang, Ning Liu, Rusheng Peng, Qinjun Huang

“…The results indicated that the D × M population had superior diameter at breast height (DBH), tree height (H), and volume (V) compared to the M × D population, while the height-to-diameter ratio (HDR) was lower. …”
Get full text

Relationship between vaginal and gut microbiome and pregnancy outcomes in eastern Ethiopia: a protocol for a longitudinal maternal-infant cohort study (the EthiOMICS study) by Piet Cools, Alemseged Abdissa, Abera Kenay Tura, Nega Assefa, Merga Dheresa, Kedir Teji Roba, Tara Wilfong, Tesfaye Assebe Yadeta, Fitsum Weldegebreal, Desalegn Admassu Ayana, Akewok Sime Negesa, Yohannes Mulugeta Demmu, Tewodros Tesfa, Tegbaru Nibrat Alemu, Tadesse Gure Eticha, Abraham Geremew, Abel Abera Negash

“…Postnatally, newborns’ skin swabs (at birth) and rectal swabs will be obtained until 2 years of age. Moreover, breast milk samples at birth and 6 months and environmental samples (water, indoor air and soil) will be collected at enrolment, birth, 6, 12 and 24 months post partum. …”
Get full text

Bifidobacterium fermentation with infant formulas is associated with benefits for gut and brain barrier function by Emily G. Knox, Paula Sánchez-Díaz, Colin Buttimer, Sarah-Jane Leigh, Klara Vlckova, Colin Hill, Elaine Kennedy, Jonathan O’Regan, Seamus McSweeney, David Goulding, Maria Rodriguez Aburto, Caitriona M. O’Driscoll, John F. Cryan, Eoin Gunnigle, Gerard Clarke

“…The gut and blood-brain barrier are essential components of the microbiota-gut-brain axis and are influenced by diet, particularly in infancy. Breast milk supports gut and brain barrier function, but infant formulas often lack key protective components. …”
Get full text

Biomimetic Targeted Co‐Delivery System Engineered from Genomic Insights for Precision Treatment of Osteosarcoma by Tianqi Luo, Zhijin Fan, Anyu Zeng, Anqi Wang, Yuanwei Pan, Yanyang Xu, Hongmin Chen, Weiqing Chen, Dingmeng Nie, Jiaming Lin, Anfei Huang, Ming Gong, Yufeng Huang, Yun Ding, Xiaojun Zhu, Lang Rao, Jin Wang

Get full text

The practice and exploration of SPOC-based online-offline mixed teaching mode in Traditional Chinese Medicine nursing teaching (基于SPOC的线上-线下混合式教学模式在中医护理教学中的实践与探索)... by WANG Li (王黎), MA Xueling (马雪玲), WANG Zhen (王臻), CHEN Hong (陈宏), WENG Zhiwen (翁志文), WANG Junxiang (王俊翔)

Get full text

Estimation of mangrove carbon stocks using unmanned aerial vehicle over coastal vegetation by S.H. Larekeng, M. Nursaputra, M.F. Mappiasse, S. Ishak, M. Basyuni, E. Sumarga, V.B. Arifanti, A.A. Aznawi, Y.I. Rahmila, M. Yulianti, R. Rahmania, A. Mubaraq, S.G. Salmo III, H. Ali, I. Yenny

“…Field surveys were conducted to determine the species composition of each mangrove stand and measure their diameter at breast height. The allometric formula was then used to calculate mangrove biomass, which was subsequently converted into carbon stock values. …”
Get full text

TP53 germline testing and hereditary cancer: how somatic events and clinical criteria affect variant detection rate by Paula Rofes, Carmen Castillo-Manzano, Mireia Menéndez, Álex Teulé, Sílvia Iglesias, Elisabet Munté, Mireia Ramos-Muntada, Carolina Gómez, Eva Tornero, Esther Darder, Eva Montes, Laura Valle, Gabriel Capellá, Marta Pineda, Joan Brunet, Lidia Feliubadaló, Jesús del Valle, Conxi Lázaro

“…Methods TP53 was analyzed in 6161 suspected hereditary cancer non-related patients categorized into three subgroups: (1) 495 patients fulfilling any LFS/Chompret clinical criteria; (2) 2481 patients diagnosed with early-onset breast/colorectal cancer; (3) 3185 patients without clinical criteria suggestive of hTP53rc. …”
Get full text

Dietary Se-enrich Cardamine violifolia supplementation decreases lipid deposition and improves antioxidant status in the liver of aging laying hens by Mengke Yan, Xin Cong, Hui Wang, Kun Qin, Yuhui Tang, Xiao Xu, Dan Wang, Shuiyuan Cheng, Yulan Liu, Huiling Zhu

“…Dietary SEC + SEY and SEY supplementation increased (P < 0.05) Se content in egg yolk and breast muscle compared to CON diet. Dietary SEC, SEY or SEC + SEY supplementation increased (P < 0.05) the activity of antioxidant enzymes (GSH-PX, T-AOC and T-SOD) in the plasma and liver and decreased (P < 0.05) MDA content in the plasma compared to CON diet. …”
Get full text

Nursing of a patient with COPD complicated with type II respiratory failure treated by sequential non-invasive positive pressure ventilation via nasal high-flow oxygen therapy (经鼻高... by QIAO Xinli (乔新立), MA Hailian (马海莲), LI Na (李娜), CHEN Hong (陈宏), TANG Ling (唐玲), ZHANG Ning (张宁), WANG Jingjing (王晶晶), ZHANG Tingting (张婷婷), ZHOU Jie (周洁)

Get full text

Investigating the Effect of Solanum lycopersicum L. (Tomato) Pomace on Growth Performance and some Blood Indices of Broiler Chickens by Meta-Analysis Method by Zahra Sahragard, seyyed javad Hosseini-vashan, Hossein Naeemipour Younesi, Seyyed Homayon Farhangfar

“…The effect of inclusion of tomato pomace on weight gain during the growth period, feed intake in all periods and FCR in the starter, grower, and finisher period, the blood concentration of triglyceride, glucose, and the percentage of abdominal fat, liver, heart, pancreas and gall bladder, also breast was not significantly affected by tomato pomace. …”
Get full text

An integrative analysis reveals cancer risk associated with artificial sweeteners by Jumin Xie, Ying Zhu, Zixuan Yang, Zhang Yu, Mingzhi Yang, Qingzhi Wang

“…Conclusion This study integrated data mining, machine learning, network toxicology, molecular docking, molecular dynamics simulations, and clinical sample analysis to demonstrate that AS increases the risk of kidney cancer, low-grade glioma, breast cancer, and prostate cancer through multiple targets and signaling pathways. …”
Get full text

Effect of Autolyzed Yeast on Performance and Physiological Indices of Broiler Chickens Reared at High Stock Density by Samaneh Ghaseminejad, Smayyeh Salari

“…On the 37th day of the experiment, two birds from each replicate were randomly selected and the weight of different parts of the carcass including the weight of gastrointestinal tract, breast, thigh, gizzard, liver, pancreas, and spleen (as a percentage of live body weight) were recorded. …”
Get full text

Effects of replacing soybean meal with cottonseed meal on growth performance, carcass trait, intestinal development and intestinal microbiota of broiler chickens by Lei Yan, Sha An, Xiaoguo Lv, Zunzhou Lv, Beibei Zhang, Mingan Choct, Yuming Guo, Zhengguo Wang, Baozuo Yan, Yong Li

“…Moreover, 5 % and 10 % CSM significantly decreased breast meat pH in 24 h (P < 0.05). Cottonseed meal had no significant effect on the alpha diversity, beta diversity, and taxonomic composition at the phylum and genus levels of the ileal microbiota in broilers (P > 0.05). …”
Get full text

A study of relationship between cardiac exposure dose-volume and cardiovascular autonomic dysfunction in radiotherapy by CHEN Hongyu, SU Pengyu, LUO Wenzi, PANG Dequan, WANG Feiran

“…Inclusion criteria: ① Patients who were pathologically confirmed to have malignant tumors (lung cancer breast cancer or esophageal cancer); ② patients with radiation therapy indications as recommended by the guidelines; ③ patients with an ECOG score of 0-1; ④ patients with no significant abnormalities in electrocardiogram and echocardiography results. …”
Get full text

Social vulnerability and genetic service utilization among unaffected BRIDGE trial patients with inherited cancer susceptibility by Jemar R. Bather, Melody S. Goodman, Adrian Harris, Guilherme Del Fiol, Rachel Hess, David W. Wetter, Daniel Chavez-Yenter, Lingzi Zhong, Lauren Kaiser-Jackson, Rachelle Chambers, Richard Bradshaw, Wendy Kohlmann, Sarah Colonna, Whitney Espinel, Rachel Monahan, Saundra S. Buys, Ophira Ginsburg, Kensaku Kawamoto, Kimberly A. Kaphingst, on behalf of the BRIDGE research team

Get full text

Investigating POU3F4 in cancer: Expression patterns, prognostic implications, and functional roles in tumor immunity by Weiwei Chen, Yaya Ji, Rui Wang, Ruijie Ji, Yujian Lin, Yuhang Wu, Lehan Liu, Tianle Sha, Wen Li, Lei Zhang, Longfei Yang, Xinhua Zhang, Jianxiang Song

“…The analysis revealed that POU3F4 expression is typically low in most cancers but is elevated in breast invasive carcinoma, glioblastoma multiforme (GBM), liver hepatocellular carcinoma, and thyroid carcinoma, with the highest levels in GBM. …”
Get full text

Derivation of allometric equations and carbon content estimation in mangrove forests of Malaysia by Waseem Razzaq Khan, Michele Giani, Stanislao Bevilacqua, Shoaib Ahmad Anees, Kaleem Mehmood, M. Nazre, Abdul Aziz Bin Abdul Haddy, Abang Norizan Bin Abang Median, Japanie Bin Bujang, Fatin-Norliyana Mohamad-Ismail, Johar Mohamed, Zaiton Samdin, Rambod Abiri, Tuan-Marina Tuan-Ibrahim, Lydia-Suzieana Mohammad, Hamid-Reza Naji, Seemab Akram, Hazandy Abdul-Hamid, Timothy Dube

“…We measured 1403 trees across ten species, with Rhizophora apiculata identified as the dominant species. Using diameter at breast height (DBH) and tree height, we developed site species-specific allometric equations to estimate aboveground biomass. …”
Get full text