Twist-Induced Epithelial-to-Mesenchymal Transition Confers Specific Metabolic and Mitochondrial Alterations by Haleigh N. Parker, Kayla L. Haberman, Tolulope Ojo, Juli Watkins, Adhwaitha Nambiar, Kayla Morales, Bernd Zechmann, Joseph H. Taube

“…Here, we analyze Twist-induced EMT in non-transformed HMLE cells as well as a breast cancer cell line with (MDA-MB-231) and without (MCF7) EMT features to compare differences in metabolic pathways and mitochondrial morphology. …”
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Fertility, gestation outcome and parasite congenital transmissibility in mice infected with TcI, TcII and TcVI genotypes of Trypanosoma cruzi. by Sabrina Cencig, Nicolas Coltel, Carine Truyens, Yves Carlier

“…Altogether, the results show that: i) for the three strains tested, acute infection occurring after the embryo implantation in the uterus (parasite inoculation 4 days before mating), or close to delivery (parasite inoculation on day 13 of gestation), prevents or severely jeopardizes gestation outcome (inducing pup mortality and intra-uterine growth retardation); ii) for the three strains tested, gestation during chronic infection results in intra-uterine growth retardation, whereas re-inoculation of TcVI parasites during gestation in such chronically infected mice, in addition, strongly increases pup mortality; iii) congenital infection remains a rare consequence of infection (occurring in approximately 4% of living pups born to acutely infected dams); iv) PCR, detecting parasitic DNA and not living parasites, is not convenient to detect congenial infection close to delivery; v) transmission of parasites by breast milk is unlikely. This study should encourage further investigations using other parasite strains and genotypes to explore the role of virulence and other factors, as well as the mechanisms of such effects on gestation and on the establishment of congenital infection.…”
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Sociobiology meets oncology: unraveling altruistic cooperation in cancer cells and its implications by Muhammad Sufyan bin Masroni, Evelyn Siew-Chuan Koay, Victor Kwan Min Lee, Siok Bian Ng, Soo Yong Tan, Karen Meiling Tan, Marco Archetti, Sai Mun Leong

“…Against the backdrop of existing knowledge on various social organisms found in nature, we explore the mechanisms underlying the manifestation of altruism within breast tumors, revealing a complex interplay of seemingly counteracting cancer signaling pathways and processes that orchestrate the delicate balance between cost and benefit underlying altruistic cooperation. …”
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Dynamic Modeling of Needle-Tissue Interaction Applied to Soft Tissue Damage During Needle Extraction by Erick D. Chavez Pereda, Hernan A. Gonzalez Rojas, Antonio J. Sanchez Egea

“…A hypodermic needle was inserted into ex vivo turkey breast tissue at different insertion speeds. The size of the tissue hole and the friction stress from the needle-tissue interaction were used to measure damage and develop the damage model. …”
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Synthesis and Characterization of Iodinated Chitosan Nanoparticles and Their Effects on Cancer Cells by Germán Alvarado Tenorio, Roberto Espinosa Neira, Carlos Alberto Ávila Orta, Gabriela Yolotzín Romero Zúñiga, Hortensia Ortega Ortiz

“…The cytotoxic effects on human tumor cells of chitosan and iodine-modified chitosan nanoparticles (CSNPs-I and CSNPs-IO3) were evaluated for 24 h in a range from 0.15 mg/mL to 0.95 mg/mL concentrations, where CSNPs-IO3 presented the lower viability for lung cancer A549, followed by cervical cancer HeLa cell and finally breast cancer MDA-MB-231, with a weight content of iodate ion in a range of 8.7 to 15 μg. …”
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Comparison of molecular analysis results determined by next-generation sequencing to immunohistochemical indicators and clinicopathological parameters in prostate adenocarcinomas by Merve Çırak Balta, İbrahim Halil Erdoğdu, Esin Oktay, Nil Çulhac

“…Results: As a result of statistical analysis, a significant relationship was found between the pathogenic mutation detected in androgen receptor and Breast Cancer Gene 2 genes and tumour volume. In all cases with a pathogenic mutation in the androgen receptor gene, a pathogenic mutation in the Protein Tyrosine Phosphatase and Tensin Homolog gene was also observed and a significant relationship was found between them. …”
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Incidence and Evaluation of Incidental Abnormal Bone Marrow Signal on Magnetic Resonance Imaging by Gunjan L. Shah, Aaron S. Rosenberg, Jamie Jarboe, Andreas Klein, Furha Cossor

“…One patient who had not undergone evaluation developed breast cancer 24 months after the MRI. Conclusions. …”
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Synthesis of Some Polysubstituted Nicotinonitriles and Derived Pyrido[2,3-d]pyrimidines as In Vitro Cytotoxic and Antimicrobial Candidates by Hassan M. Faidallah, Sherif A. F. Rostom, Khalid A. Khan

“…They were evaluated for their in vitro cytotoxic effects against three different human tumor cell lines (human colon carcinoma HT29, hepatocellular carcinoma Hep-G2, and Caucasian breast adenocarcinoma MCF7). Nine compounds displayed variable cytotoxic potential, among which alkylthio analogs 33, 34, and 37 emerged as the most active members, being almost twice as active as doxorubicin against the colon carcinoma HT29 cell line. …”
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Use of morphometry in the arborization of Paragominas city, Pará, Brazil, with Handroanthus impetiginosus (Mart. ex DC.) Mattos (Bignoniaceae) by Victor Pereira de Oliveira, Michael Douglas Roque Lima, Walmer Bruno Rocha Martins

“…Mean values for Total Height (TH), Canopy Width (CW), Diameter at Breast Height (DBH) and Canopy Diameter (CD) were 6.48, 3.98, 0.19 and 4.95, respectively. …”
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Profil Tumor Ganas Ovarium di Laboratorium Patologi Anatomi Fakultas Kedokteran Universitas Andalas Periode Januari 2011 Sampai Desember 2012 by Iwani Rahmah Rambe, Aswiyanti Asri, Adrial .

“…<br />Kata kunci: tumor ganas ovarium, paritas, sel asal tumor</p><p>Abstract<br />Malignant ovarian tumour is third rank after malignant cervic tumour and malignant breast tumour that cause death in Indonesia. The research found 143 cases of malignant ovarian tumours. …”
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Effect of Forest Management on Carbon Stock of Tropical Moist Afromontane Forest by Damena Edae Daba, Bikila Workineh Dullo, Teshome Soromessa

“…A total of 100 main plots of 400 m2 were laid to record trees and shrubs with a diameter at breast height (DBH) ≥ 5 cm. The soil data were collected from 1 m2 subplots established at the four corners and the center of each main plot. …”
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Impacts of Filtration on Contrast-Detail Detectability of an X-ray Imaging System

“…The corresponding X-ray spectra and contrast-detail detectabilities were measured using two phantoms of different thicknesses simulating breast tissue under different exposures. The added Mo filters reduced the low-energy as well as the high-energy photons, hence providing a narrowband for imaging quality improvement. …”
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Rheological Characterization and Printability of Sodium Alginate–Gelatin Hydrogel for 3D Cultures and Bioprinting by Mohan Kumar Dey, Ram V. Devireddy

“…The optimized 7% alginate and 8% gelatin blend demonstrated favorable printability, mechanical strength, and cell compatibility with MDA-MB-213 breast cancer cells, exhibiting high cell proliferation rates and minimal cytotoxicity over a 2-week culture period. …”
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Analysis of single nucleotide polymorphism of p16 gene in cytological samples of patients with oral potentially malignant disorders (OPMD) and oral squamous cell carcinoma (OSCC) by Neetu Oommen, Vasanthi V, Ramya Ramadoss, Rajkumar Krishnan

“…Frequent homozygous deletions of the pl6 gene have been reported in many tumor cell lines including the brain, breast, osteosarcomas, melanomas, kidney, bladder, and ovary. …”
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Insights into the mechanism of antiproliferative effects of primaquine-cinnamic acid conjugates on MCF-7 cells by Mabeta Peace, Pavić Kristina, Zorc Branka

“…Compound 1 induced significant growth inhibition in the colorectal adenocarcinoma (SW620), human breast adenocarcinoma (MCF-7) and cervical carcinoma (HeLa) cell lines, while compounds 2 and 3 selectively inhibited the growth of MCF-7 cells. …”
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Exploring the prognosis of calponin h1 in carcinogenesis: A novel target in biomedical research by Roshna Sankar, Sharon John, Priya Devi, Sameer Gupta, Shalini Gupta

“…Calponin plays varied roles in different types of cancer, such as stomach adenocarcinoma, bladder, colorectal, oral malignancies, fibrosarcoma, lung squamous cell carcinoma, breast and leiomyosarcoma. Its functions may also vary in terms of tissue specificity and varying expression levels. …”
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A High-Status Middle Sarmatian Burial from the Kovalevka Burial Complex in the Volgograd Region by Valeriy M. Klepikov

“…The set of three phalars, which can be functionally defined as breast and shoulder plates of a horse harness, was found on the other side of the cauldron. …”
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Quantum computational infusion in extreme learning machines for early multi-cancer detection by Anas Bilal, Muhammad Shafiq, Waeal J. Obidallah, Yousef A. Alduraywish, Haixia Long

“…Results demonstrate that Q-GBGWO-ELM improves diagnostic accuracy by an average of 6.5% compared to traditional methods, with notable accuracy rates across various cancers: 98.80% for breast cancer, 92.30% for brain tumors, 97.00% for skin cancer, and 96.98% for lung cancer. …”
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Comparison of ropivacaine with ropivacaine–dexamethasone combination for postoperative analgesia in the pectoral nerve block for modified radical mastectomy: A randomized clinical... by Veena Mathur, Brijesh Kumari, Anand Kumar Verma, Arvind Khare, Deepak Kumar Garg

“…Methods: This prospective, randomized, double-blind study was conducted on a total of 80 women with breast cancer belonging to American Society of Anesthesiologist class I and II scheduled for MRM, which were randomly allocated into two groups – Group R (n = 40) received 0.25% ropivacaine 29 ml + NS 1 ml and Group RD (n = 40) received 0.25% ropivacaine 29 ml + dexamethasone (4 mg) 1 ml. …”
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Immune Cell Profiling Reveals a Common Pattern in Premetastatic Niche Formation Across Various Cancer Types by Shigeaki Sugiyama, Kanae Yumimoto, Keiichi I. Nakayama

“…Materials and Methods We performed comprehensive flow cytometric analysis of lung and peripheral immune cells at three time points (early premetastatic, late premetastatic, and micrometastatic phases) for mice with subcutaneous implants of three types of cancer cells (breast cancer, lung cancer, or melanoma cells). The immuno‐cell profiles were then used to predict the metastatic phase by machine learning. …”
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