The Impact of Immune System in Regulating Bone Metastasis Formation by Osteotropic Tumors by Lucia D’Amico, Ilaria Roato

“…Bone metastases are frequent and debilitating consequence for many tumors, such as breast, lung, prostate, and kidney cancer. Many studies report the importance of the immune system in the pathogenesis of bone metastasis. …”
Get full text

Constipation treatment safety at pregnancy by O. Z. Okhlobystina

“…Polyethylene glycol-containing laxatives, are safe and recommended as treatment of choice in constipation at pregnant and breast-feeding women. Macrogol-4000 is not metabolized and not absorbed, having therefore no undesirable effect on fetus.Conclusion. …”
Get full text

RPE Adenocarcinoma as the Presenting Sign of Bronchogenic Carcinoma: Diagnostic Dilemma in the Management of a Case by Namrata Adulkar, Santhi Radhakrishnan, N. Vidhya, Usha Kim

“…The possibility of a metastatic disease with possible primary sites as lung, breast, or kidney should be ruled out. Herein we report a case of adenocarcinoma arising from the RPE with a lung lesion suspicious of bronchogenic carcinoma. …”
Get full text

Revisiting Estrogen: Efficacy and Safety for Postmenopausal Bone Health by Sandra M. Sacco, Wendy E. Ward

“…While hormone therapy (HT) is an effective means to re-establish endogenous estrogen levels and reduce the risk of future fracture, its use can be accompanied by undesirable side effects such as stroke and breast cancer. In this paper, we revisit the issue of whether HT can be both safe and effective for the prevention of postmenopausal bone loss by examining standard and alternative doses and formulations of HT. …”
Get full text

Nanoparticle Albumin-Bound-Paclitaxel in the Treatment of Metastatic Urethral Adenocarcinoma: The Significance of Molecular Profiling and Targeted Therapy by Yasmin M. Abaza, Carlos Alemany

“…Nanoparticle albumin-bound-paclitaxel has been shown to be effective in the treatment of a number of malignancies including metastatic breast, pancreatic, and bladder cancer. We present a 67-year-old woman with advanced metastatic urethral adenocarcinoma resistant to two lines of chemotherapy (ifosfamide/paclitaxel/cisplatin and irinotecan/5-fluorouracil/leucovorin) that showed a dramatic response to nanoparticle albumin-bound-paclitaxel. …”
Get full text

Comunicación y empoderamiento ciudadano en salud: un caso de investigación-acción en la Venezuela polarizada by Nahón-Serfaty, Isaac, Eid, Mahmoud

“…An action-research project was implemented in Venezuela from 2009-2013 to empower social activists and patients in their fight against breast cancer (BC). The project was implemented in a context of high political and social polarization of the so-called «Bolivarian revolution». …”
Get full text

Peutz–Jeghers syndrome – Be in need of vigilance: A case report by Vandana S. Tomey, Sudhir Tomey, Kewal Dhone, Tanmay Tapase

“…Peutz–Jeghar syndrome (PJS) is an inherited condition that puts people at an increased risk for developing hamarotmatous polyps in the digestive tract as well as cancers of the breast, colon, rectum, pancreas, stomach, testicles, ovaries, lung and cervix. …”
Get full text

Specification of manual lactation traditional Chinese medicine technology by Siyao Wang, Ye Li, Xuejing Li, Yingyi Fan, Wei Xie, Xueting Mei, Ling Tang

“…Manual lactation traditional Chinese medicine technology is one of the important measures to improve the rate of breastfeeding, which can solve the problems of breast swelling, pain, and reduction of milk production. …”
Get full text

Cytotoxicity of Alkyl Derivatives of Protocetraric Acid by Danielle Bogo, Glaucia Alcantara, Ana Camila Micheletti, Neli Honda, Maria de Fátima Cepa Matos

“…In this work, we evaluated through the sulforhodamine B (SRB) assay the cytotoxic activity of seven alkyl ether derivatives of protocetraric acid (9´-O-alkyl protocetraric acid) against the following cell lines: HT-29 (colon carcinoma), 786-0 (kidney carcinoma), MCF7 (breast carcinoma), HEP2 (laryngeal carcinoma), PC-03 (prostate carcinoma), B16F10 (murine melanoma), UACC-62 (human melanoma), and NIH/3T3 (mouse embryonic fibroblast).  …”
Get full text

Delayed Diagnosis of McCune–Albright Syndrome by Bereket Fantahun, Seblewongel Desta

“…We report a female child who was symptomatic since the neonatal period with skin hyperpigmentation, breast enlargement, and vaginal bleeding. She was diagnosed with MAS at the age of five years. …”
Get full text

Interaction among Cells of Bone, Immune System, and Solid Tumors Leads to Bone Metastases by Ilaria Roato

“…Bone metastases are a dismal consequence for different types of solid tumors, such as breast, prostate, lung, and kidney cancer. The mechanisms regulating the interactions among bone, immune system, and tumor cells have been deeply investigated, and many studies are ongoing to define the specific role of the different cells in the bone metastatic process. …”
Get full text

Multiple Extramedullary Plasmacytoma with Lytic Bony Lesions: A Rare Case Report by Akhlak Hussain, Mohinder Singh, Kuldip Singh, Harjot Bagga

“…Multiple extramedullary plasmacytoma lesions involving subcutaneous tissue, breast, mediastinal tissue, spleen, and soft tissue of pelvic region along with multiple bones plasmacytomas without marrow plasmacytosis are a very rare presentation. …”
Get full text

Wings for life in the Guamuhaya Butterflies: the importance of a project by Eneida Bravo Polanco, Asleny Sánchez Leandro

“…During 2020, 3,887 people in Cuba were diagnosed with breast cancer, which represents a rate of 39.6, and 1,714 died, for a rate of 30.4. …”
Get full text

Bilateral De Quervain Syndrome after Aromatase Inhibitor Administration: A Case Report and Review of the Literature by Konstantinos Papadimitriou, Panteleimon Kountourakis, Emmanouil Morakis, Vassilios Vassiliou, Vasileios Barbounis, Alexandros Ardavanis

“…Aromatase inhibitors are widely used as one of the main treatment options of both early and advanced hormone receptor-positive breast cancer in postmenopausal women. Unfortunately, musculoskeletal symptoms are often presented in patients treated with aromatase inhibitors (AIs), and, although the pathogenesis is unknown, postulated mechanisms have been described. …”
Get full text

Anti-K1 (Kell) Antibody Expressed in Maternal Breastmilk: A Case Report of a Neonate with Multiple Intrauterine Transfusions and Postnatal Exposure to Kell Antibody in Maternal Bre... by Patrick DeMoss, Mohamed Asfour, Kelly Hersey

“…We review the pathophysiology of anti-Kell antibodies, the immunology of breast milk, and the intersection of these two topics.…”
Get full text

A morphometric signature to identify ductal carcinoma in situ with a low risk of progression by Marcelo Sobral-Leite, Simon P. Castillo, Shiva Vonk, Hendrik A. Messal, Xenia Melillo, Noomie Lam, Brandi de Bruijn, Yeman B. Hagos, Myrna van den Bos, Joyce Sanders, Mathilde Almekinders, Lindy L. Visser, Emma J. Groen, Petra Kristel, Caner Ercan, Leyla Azarang, Jacco van Rheenen, E. Shelley Hwang, Yinyin Yuan, Grand Challenge PRECISION Consortium, Renee Menezes, Esther H. Lips, Jelle Wesseling

“…Abstract Ductal carcinoma in situ (DCIS) may progress to ipsilateral invasive breast cancer (iIBC), but often never will. Because DCIS is treated as early breast cancer, many women with harmless DCIS face overtreatment. …”
Get full text

Determinants of formula feeding among mothers with infants and young children in six Sub Sahara African countries: Multilevel analysis of data from demographic and health survey. by Mohammed Seid Ali, Alebachew Ferede Zegeye, Belayneh Shetie Workneh, Gebreeyesus Abera Zeleke, Enyew Getaneh Mekonen, Agazhe Aemro, Berhan Tekeba, Tadesse Tarik Tamir, Mulugeta Wassie, Bewuketu Terefe

“…<h4>Introduction</h4>Formula feeding is providing infants with prepared formula as an alternative to or alongside breastfeeding. While breast milk is widely regarded as the optimal source of nutrition for infants, formula feeding is a common practice. …”
Get full text

Effects of supplementation with vitamin D3 on growth performance, lipid metabolism and cecal microbiota in broiler chickens by Jiawei Li, Ximei Li, Jiamin Tian, Linna Xu, Yan Chen, Susu Jiang, Guohua Zhang, Jianxiong Lu

“…Supplementary VD3 significantly enhanced average daily gain (ADG) in broilers aged 57-84 d and 1-84 d, and increased leg muscle rate and fat content in breast and leg muscles and reduced abdominal fat rate of broilers at 84 d. …”
Get full text

Blockades of effector T cell senescence and exhaustion synergistically enhance antitumor immunity and immunotherapy by Xia Liu, Emily Shaw, Fusheng Si, Guangyong Peng, Yan Tao, Feiya Ma, David Bagley, Yuanqin Zhang

“…Therefore, a better understanding of the molecular mechanism responsible for T cell senescence in the TME and development of novel strategies to prevent effector T cell senescence are urgently needed for cancer immunotherapy.Methods Senescent T cell populations in the TMEs in mouse lung cancer, breast cancer, and melanoma tumor models were evaluated. …”
Get full text

Human Serum Albumin and Human Serum Albumin Nanoparticles as Carriers of 10-(2′-Pyrimidyl)-3,6-diazaphenothiazine: In Vitro Spectroscopic Studies by Aleksandra Owczarzy, Karolina Kulig, Beata Morak-Młodawska, Małgorzata Jeleń, Tammam Muhammetoglu, Wojciech Rogóż, Małgorzata Maciążek-Jurczyk

“…Due to nontoxicity and biocompatibility, this protein can be used as a nanocarrier. 10-(2′-Pyrimidyl)-3,6-diazaphenothiazine (10-Pyr-3,6-DAPT) is a phenothiazine showing high anticancer potential in vitro against glioma, melanoma and breast cancer cells. Additionally, this compound is characterized by selectivity of action towards MCF-7 breast cancer and has low cytotoxicity towards normal cells. …”
Get full text