Genetic Variants Associated with Chronic Obstructive Pulmonary Disease Risk: Cumulative Epidemiological Evidence from Meta-Analyses and Genome-Wide Association Studies by Caiyang Liu, Ran Ran, Xiaoliang Li, Gaohua Liu, Xiaoyang Xie, Ji Li

Get full text

Nano-Azo Ligand and Its Superhydrophobic Complexes: Synthesis, Characterization, DFT, Contact Angle, Molecular Docking, and Antimicrobial Studies by Gehad G. Mohamed, Walaa H. Mahmoud, Ahmed M. Refaat

“…The binding between H2L and its Cd(II) complex with receptors of the crystal structure of S. aureus (PDB ID: 3Q8U), crystal structure of protein phosphatase (PPZ1) of Candida albicans (PDB ID: 5JPE), receptors of breast cancer mutant oxidoreductase (PDB ID: 3HB5), and crystal structure of Escherichia coli (PDB ID: 3T88) was predicted and given in detail using molecular docking.…”
Get full text

Gallbladder Carcinomas: An Immunoprognostic Evaluation of P53; Bcl-2; CEA and Alpha-Fetoprotein by R Kanthan, JM Radhi, SC Kanthan

“…The p53 gene is the most frequently mutated gene in many human cancers, including those of the colon, breast, lung, esophagus, liver and brain. Such genetically mutated tumours are generally associated with progression of the disease and poor clinical outcome. …”
Get full text

When a sore throat turns into deadly multiple serous cavity effusions: the role of Prevotella oris in rapidly progressing infection—a case report by Fangqi Zhang, Juan-Li Wang, Jian Zhu, Shaokui Si, Hao Guo, Xiang Yue, Wei Wen

Get full text

The Association of Autoantibodies in Hyperthyroid Heart Disease Combined with Pulmonary Hypertension by Xiujuan Zhang, Lin Chen, Jianping Sheng, Chaoying Li, Yong He, WenXia Han

Get full text

Synthesis, Characterization, Anticancer, and Antioxidant Studies of Ru(III) Complexes of Monobasic Tridentate Schiff Bases by Ikechukwu P. Ejidike, Peter A. Ajibade

“…In vitro anticancer studies of the synthesized complexes against renal cancer cells (TK-10), melanoma cancer cells (UACC-62), and breast cancer cells (MCF-7) was investigated using the Sulforhodamine B assay. …”
Get full text

Drug Target Investigation of <i>N</i>-<i>p</i>-Coumaroyl-<i>N</i>’-Caffeoylputrescine, a Naturally-Occurring Alkaloid Derived from <i>Saxifraga tangutica</i> by Chuang Liu, Jun Dang, Minchen Wu

“…An in vitro study on liver (HepG2) cells and breast (MCF-7) cancer cells revealed that PCC modulates HSP90AA1, subsequently affecting Mut-p53 expression, triggering a cascade effect that reduced adriamycin-induced drug resistance in cells. …”
Get full text

Comparative Study of Gleason 7 (3+4) and (4+3) Prostatic Adenocarcinomas with Prognostic Criteria and Immunohistochemical Profiles of AMACR, PSA and Ki-67 by Clarice F. E. M. Osório, Waldemar S. Costa, Carla B. M. Gallo, Luciano A. Favorito, Francisco J. B. Sampaio

“…Proportion and intensity criteria were used to quantify the anti-PSA antibody and for the anti-Ki 67 antibody, the quantification by similarity of this antibody in breast carcinomas. Anti-AMACR protein expression was based on four scores: negative, weak, moderate and strong. …”
Get full text

Thinning enhances whitebark pine (Pinus albicaulis) growth and resin duct defenses by Nickolas E. Kichas, Erin K. Shanahan, Sharon M. Hood

“…In the nine years following thinning treatments, we found that whitebark pine trees (>12.7 cm diameter at breast height [dbh]) responded favorably to thinning and experienced a 60% increase in basal area increment (52% increase in ring width index) while also producing 34% more resin ducts. …”
Get full text

Human microbiomes in cancer development and therapy by Chenglai Xia, Jiyan Su, Can Liu, Zhikai Mai, Shuanghong Yin, Chuansheng Yang, Liwu Fu

Get full text

Real-world clinical multi-omics analyses reveal bifurcation of ER-independent and ER-dependent drug resistance to CDK4/6 inhibitors by Zhengyan Kan, Ji Wen, Vinicius Bonato, Jennifer Webster, Wenjing Yang, Vladimir Ivanov, Kimberly Hyunjung Kim, Whijae Roh, Chaoting Liu, Xinmeng Jasmine Mu, Jennifer Lapira-Miller, Jon Oyer, Todd VanArsdale, Paul A. Rejto, Jadwiga Bienkowska

“…Abstract To better understand drug resistance mechanisms to CDK4/6 inhibitors and inform precision medicine, we analyze real-world multi-omics data from 400 HR+/HER2- metastatic breast cancer patients treated with CDK4/6 inhibitors plus endocrine therapies, including 200 pre-treatment and 227 post-progression samples. …”
Get full text

Umbrella review of adjuvant photodynamic therapy for cholangiocarcinoma palliative treatment by Hanhan Chen, Honglin Li, Huijie Li, Zhen Zhang

Get full text

Seabuckthorn juice alleviates allergic symptoms in shrimp-induced food allergy mice by Hong Ren, Xiaofan Zhu, Shiyu Zhai, Xiaoping Feng, Zhuomin Yan, Jiao Sun, Ye Liu, Zhenpeng Gao, Fangyu Long

Get full text

Synthesis, Spectral Characterization, and Thermal and Cytotoxicity Studies of Cr(III), Ru(III), Mn(II), Co(II), Ni(II), Cu(II), and Zn(II) Complexes of Schiff Base Derived from 5-H... by Amani S. Alturiqi, Abdel-Nasser M. A. Alaghaz, Reda A. Ammar, Mohamed E. Zayed

“…The cytotoxic activities of all inspected compounds were evaluated towards human breast (MCF-7) and lung cancer (A549) cell lines.…”
Get full text

Can a physical activity program improve functional capacity and fatigue in people with cancer? A retrospective analysis by Aline Reinmann, Edouard Laré, Anne-Violette Bruyneel, Joseph Gligorov, Alexandre Bodmer, Thibaud Koessler

“…Results Among the 264 participants (age 57.36 ± 12.43 years; 189 women; 134 with breast cancer), 125 (47%) completed the program. Walking capacity (+ 41.63 ± 91.00 m) and fatigue (-2.01 ± 3.77) were improved after the program (p < 0.001). …”
Get full text

Clinical Application of Autologous Adipose Stem Cells in Patients with Multiple Sclerosis: Preliminary Results by Adam Stepien, Natalia L. Dabrowska, Marzena Maciagowska, Renata Piusinska Macoch, Aleksandra Zolocinska, Slawomir Mazur, Katarzyna Siennicka, Emilia Frankowska, Rafał Kidzinski, Małgorzata Chalimoniuk, Zygmunt Pojda

Get full text

Efficient Implementation of Mahalanobis Distance on Ferroelectric FinFET Crossbar for Outlier Detection by Musaib Rafiq, Yogesh Singh Chauhan, Shubham Sahay

“…The proposed implementation utilizes two crossbar arrays of ferroelectric FinFETs to calculate the Mahalanobis distance and detect outliers in the popular Wisconsin breast cancer dataset using a novel inverter-based threshold circuit. …”
Get full text

Association between Endocrine Disrupting Phenols in Colostrums and Maternal and Infant Health by B. Yi, C. Kim, M. Park, Y. Han, J. Y. Park, M. Yang

“…We performed biomonitoring of these phenols in colostrums to assess risk of the phenols in breast-fed neonates. Study subjects were the lactating mothers who delivered babies within 2 weeks (N=325; 30.67 ± 3.45 years) and their neonates (N=326; embryonic period, 39.1 ± 1.5 weeks). …”
Get full text

Vulvar Metastasis in Renal Cell Carcinoma: A Case Report Highlighting the Aggressive Nature of Clear Cell Renal Cell Carcinoma by Andreea Boiangiu, Ana-Maria Cioca, Gabriel-Petre Gorecki, Romina-Marina Sima, Liana Pleș, Marius-Bogdan Novac, Ionut-Simion Coman, Valentin-Titus Grigorean, Vasile Lungu, Mihai-Teodor Georgescu, George-Alexandru Filipescu

“…More rarely, metastases from breast cancer and renal cell carcinoma have been reported in the vulva. …”
Get full text

A Comprehensive Systematic Review of Etiology and Risk Factors of Surgical Site Infections by Aferdita Ademi, Ferizat Dika Haxhirexha, Agron Dogjani, Kastriot Haxhirexha

“…Most of the patients were operated on because of cholecystolithiasis, inguinal, ventral, and umbilical hernias, breast cancer, acute appendicitis, and neoplasia of the colon and ileus. …”
Get full text