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2021
Flavonoids as Strong Inhibitors of MAPK3: A Computational Drug Discovery Approach
Published 2023-01-01“…Mitogen-activated protein kinase 3 (MAPK3) mediates the onset, progression, metastasis, drug resistance, and poor prognosis in various malignancies, including glioma, liver, ovarian, thyroid, lung, breast, gastric, and oral cancers. Negative regulation of MAPK3 expression using miRNAs has led to therapeutic effects in cancer. …”
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2022
Experience in conducting clinical trials in Cienfuegos
Published 2018-02-01“…The highest percentage of research were aimed at confirming the efficacy and safety of product for the treatment of cancer. with the conduction of 30 clinical trials (46.8%) in locations as lungs, hematologic system, breast, head and neck and prostate. A number of 2420 patients were included. …”
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2023
Cancer Mortality by Ethnicity in Colombia Between 2011 and 2022: A Population-Based Study
Published 2025-02-01“…Compared to the Mestizo population, Raizales and Afro-Colombians experienced disproportionately higher age-standardized mortality rates due to prostate cancer (26.6/100,000 and 8.6/100,000 vs. 8.1/100,000), and for Raizales and Rom breast cancer (14.0/100,000 and 103.2/100,000 vs. 9.1/100,000).ConclusionThe disparities in cancer mortality in ethnic minorities in Colombia call for investigating cancer etiology and access to care among the Rom and the Raizal populations.…”
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2024
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2025
A comprehensive dataset of above-ground forest biomass from field observations, machine learning and topographically augmented allometric models over the Kashmir HimalayaZenodo
Published 2025-02-01“…Data were collected and generated through remote sensing techniques and extensive in-situ measurements of 6220 trees (n=275 plots), including tree diameter at breast height, species composition, and tree density to map forest area and model AGB across varied terrain. …”
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2026
Prospects for the use of <i>Bacillus anthracis</i> toxin in cancer therapy
Published 2022-12-01“…The analysis of literature demonstrated good prospects for the potential use of the lethal factor to combat such types of cancer as liver, lung, colon, breast, pancreatic, ovarian, prostate, stomach and nervous system cancers. …”
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2027
Purine-rich element binding protein alpha: a DNA/RNA binding protein with multiple roles in cancers
Published 2025-01-01“…Most recently, several studies have revealed that PURα is dysregulated in multiple cancers, such as breast cancer (BC) and esophageal squamous cell carcinoma (ESCC). …”
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2028
Investigating the effect of freezing method, voltage gradient, and probe type on quality characteristics of Turkey meat during the ohmic thawing process
Published 2025-01-01“…This research addresses the gap in efficient thawing methods by investigating the effects of ohmic thawing variables and freezing methods on the thawing speed and quality attributes of ground turkey breast, aiming to identify the optimal ohmic thawing method and compare it with traditional air and water thawing techniques. …”
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2029
Atypical Origin of Lateral Pectoral Nerve: A Case Report
Published 2025-01-01“…A thorough understanding of Pectoral Nerve (PN) anatomy is a must for surgeons practicing mastectomies, breast augmentation surgery, axillary dissection, harvesting pectoralis major muscle island flap, and dealing with trauma and fracture of the shoulder.…”
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2030
Sub-Tenon Injections of Triamcinolone Acetonide Had Limited Effect on Cystoid Macular Edema Secondary to Nanoparticle Albumin-Bound-Paclitaxel (Abraxane)
Published 2015-01-01“…A 39-year-old Japanese woman with breast cancer presents with decreased vision in both eyes while receiving nab-paclitaxel. …”
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2031
Assessment of Antioxidant and Cytotoxicity Activities of Saponin and Crude Extracts of Chlorophytum borivilianum
Published 2013-01-01“…Cytotoxicity evaluation of crude extract and total saponin fraction against MCF-7, PC3, and HCT-116 cancer cell lines using 3-(4,5-dimethylthiazol-2-yl)-2,5 diphenyltetrazolium bromide (MTT) cell viability assay indicated a higher cytotoxicity activity of the crude extract than the total saponin fraction on all cell lines, being most effective and selective on MCF-7 human breast cancer cell line.…”
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2032
Cardamom extract alleviates tamoxifen-induced liver damage by suppressing inflammation and pyroptosis pathway
Published 2025-02-01“…Abstract Tamoxifen (TAM) is extensively used to manage estrogen receptor-positive breast cancer. Despite its effectiveness, its administration can negatively impact various organs, including the liver. …”
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2033
DVGEDR: a drug repositioning method based on dual-view fusion and graph enhancement mechanism in heterogeneous networks
Published 2024-12-01“…In case study, DVGEDR identifies 10 new candidate drugs for breast cancer and COVID-19, demonstrating not only superior performance in experimental settings but also potential therapeutic advantages in clinical environments. …”
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2034
Cerebellar re-irradiation after whole brain radiotherapy significant symptom relief with minimal toxicity in metastatic brain patients
Published 2025-02-01“…The cohort’s median age was 53 years, with breast cancer being the most prevalent histology (71%). …”
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2035
A New Network-Based Strategy for Predicting the Potential miRNA-mRNA Interactions in Tumorigenesis
Published 2017-01-01“…The strategy was validated by using the data sets of acute myeloid leukemia (AML), breast invasive carcinoma (BRCA), and kidney renal clear cell carcinoma (KIRC). …”
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2036
FOTELP-VOX 2024: Comprehensive overview of its capabilities and applications
Published 2024-01-01“…This study presents the application of FOTELP-VOX in simulating absorbed dose distributions in various clinical scenarios, including radiotherapy treatment planning for salivary gland tumors, eye melanoma and breast cancer. The results demonstrate the program's capability to replicate complex dose distributions with high accuracy, in comparison with clinical techniques like volumetric modulated arc therapy and 3-D conformal radiotherapy. …”
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2037
46, XY Complete Gonadal Dysgenesis (Swyer Syndrome) Presenting as Primary Amenorrhea in a Normomorphic Adult Female From Kakamega, Kenya
Published 2025-01-01“…Physical examination revealed Tanner stage 3 breast development, Tanner stage 4 pubic hair, normal external genitalia, and a gynoid body shape. …”
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2038
Population Structure and Regeneration Status of Woody Species in Kenech Forest, Southwest Ethiopia
Published 2021-01-01“…Any woody species of trees and shrubs with the diameter at breast height (DBH) ≥2.5 cm was measured at 1.5 m from the ground. …”
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2039
Signal Persistence of Bispectral Index and State Entropy during Surgical Procedure under Sedation
Published 2012-01-01“…Methods. 28 females undergoing breast surgery under local anesthesia and sedation were studied. …”
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2040
The diagnostic and prognostic significance of HOXC13-AS and its molecular regulatory mechanism in human cancer
Published 2025-02-01“…This review summarizes the clinical significance of HOXC13-AS as a biomarker for human tumor diagnosis and prognosis and outlines the function and molecular regulation mechanism of HOXC13-AS in various types of cancer, including nasopharyngeal carcinoma, breast cancer, oral squamous cell carcinoma, glioma, and cervical cancer. …”
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