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221
PLIN1 suppresses glioma progression through regulating lipid metabolism
Published 2025-01-01“…Abstract Glioma is a common and destructive brain tumor, which is highly heterogeneous with poor prognosis. …”
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222
Glioblastoma Multiforme Stem Cells
Published 2011-01-01“…Glioblastoma multiforme (GBM) is an aggressive, malignant, and lethal brain tumor, resistant to all current forms of treatment. …”
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223
Malignant Glioma in the Cerebellum Presenting as Multiple Small Lesions
Published 2019-01-01“…Malignant glioma, the most common malignant primary brain tumor in adults, usually occurs in supratentorial space as a single mass lesion, and cerebellar location and multiple appearance are uncommon. …”
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224
Mapping naturally presented T cell antigens in medulloblastoma based on integrative multi-omics
Published 2025-02-01“…Abstract Medulloblastoma is the most frequent malignant primary brain tumor in children. Despite recent advances in integrated genomics, the prognosis in children with high-risk medulloblastoma remains devastating, and new tumor-specific therapeutic approaches are needed. …”
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225
Brain CT image classification based on mask RCNN and attention mechanism
Published 2024-11-01“…The application of machine learning, and block-chain techniques into medical image retrieval, classification and auxiliary diagnosis has become one of the research hotspots at present. Brain tumor is one of the major diseases threatening human life. …”
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226
Synergistic strategies for glioblastoma treatment: CRISPR-based multigene editing combined with immune checkpoint blockade
Published 2025-02-01“…Abstract Glioblastoma (GBM) is a primary brain tumor known for its high levels of aggressiveness and resistance to current treatments such as radiotherapy and chemotherapy. …”
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227
MicroRNAs-Proteomic Networks Characterizing Human Medulloblastoma-SLCs
Published 2016-01-01“…Medulloblastoma (MB) is the most common malignant brain tumor of pediatric age and is characterized by cells expressing stem, astroglial, and neuronal markers. …”
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228
Brain Midline Shift Measurement and Its Automation: A Review of Techniques and Algorithms
Published 2018-01-01“…Shift of midline intracranial structures helps diagnosing intracranial lesions, especially traumatic brain injury, stroke, brain tumor, and abscess. Being a sign of increased intracranial pressure, MLS is also an indicator of reduced brain perfusion caused by an intracranial mass or mass effect. …”
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229
Brain gliomas new transcriptomic discoveries from differentially expressed genes to therapeutic targets
Published 2025-01-01“…Abstract Gliomas are a prevalent form of primary malignant brain tumor, yet the intricate molecular mechanisms underlying its pathogenesis remain unclear. …”
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230
In vivo MRI visualization of growth and morphology in the orthotopic xenotrasplantation U87 glioblastoma mouse SCID model
Published 2015-12-01“…The study of tumor formation and the evaluation of new therapies for GBM require accurate and reproducible experimental brain tumor animal models. In this study we used MRI for investigation of tumor morphology and growth dynamic in an orthopic xenotransplantation immunodeficient mouse model (SCID mouse line). …”
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231
Case report: A rare case of a long-term survivor of glioblastoma who underwent two courses of hypofractionated radiotherapy as part of her care
Published 2025-02-01“…Glioblastoma (GB) is a primary brain tumor that is lethal and challenging to treat. …”
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232
Identification of CDKN3 overexpression as a marker of poor prognosis and potential therapeutic target in low-grade glioma
Published 2025-01-01“…Abstract Low-grade glioma (LGG) is a primary, slow-growing brain tumor; however, its treatment and prognosis remain challenging. …”
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233
Profiling the Secretome of Glioblastoma Cells Under Histone Deacetylase Inhibition Using Mass Spectrometry
Published 2025-02-01“…Glioblastoma (GBM) is the most aggressive brain tumor, and different efforts have been employed in the search for new drugs and therapeutic protocols for GBM. …”
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234
Radiation-Induced Growth Retardation and Microstructural and Metabolite Abnormalities in the Hippocampus
Published 2016-01-01“…Cranial radiotherapy (CRT) increases survival in pediatric brain-tumor patients but can cause deleterious effects. …”
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235
Application of Multifunctional Metal Nanoparticles in the Treatment of Glioma
Published 2025-01-01“…Yanhong Ren,1,2,* Han Yang,3,* Duo Xu,4 Zhengkui Zhang,4 Shangfeng Gao,1,4 Rutong Yu1,4 1Department of Neurosurgery, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, 221002, People’s Republic of China; 2Beijing Institute of Brain Disorders, Capital Medical University, Beijing, 100069, People’s Republic of China; 3Department of Neurology, The First Hospital of Changsha, Changsha, 410008, People’s Republic of China; 4Institute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, Jiangsu, 221002, People’s Republic of China*These authors contributed equally to this workCorrespondence: Shangfeng Gao; Rutong Yu, Email gaoshangfeng@xzhmu.edu.cn; rtyu@xzhmu.edu.cnAbstract: Glioma is the most common primary malignant brain tumor with a poor survival rate. It is characterized by diffuse and invasive growth and heterogeneity, which limits tumor identification and complete resection. …”
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236
A Critical Review of Constraint-Induced Movement Therapy and Forced Use in Children With Hemiplegia
Published 2005-01-01“…Hemiplegia is a physical impairment that can occur in childhood following head trauma, cerebral vascular accident or transient ischemic attack (stroke), brain tumor, or congenital or perinatal injury. One of the most disabling symptoms of hemiplegia is unilaterally impaired hand and arm function. …”
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237
The Effect of SP/NK1R on the Expression and Activity of Catalase and Superoxide Dismutase in Glioblastoma Cancer Cells
Published 2021-01-01“…Glioblastoma is the most malignant brain tumor with different therapeutic protocols, including surgery, radiotherapy, and chemotherapy. …”
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238
Multimodal Medical Image Fusion of Positron Emission Tomography and Magnetic Resonance Imaging Using Generative Adversarial Networks
Published 2022-01-01“…Multimodal medical fusion of brain image helps to medical practitioners to simultaneously visualize hard portion like skull and soft portion like tissue. Brain tumor segmentation can be accurately performed by utilizing the image obtained after multimodal medical image fusion. …”
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239
MAP4 kinase-regulated reduced CLSTN1 expression in medulloblastoma is associated with increased invasiveness
Published 2025-01-01“…Abstract De-regulated protein expression contributes to tumor growth and progression in medulloblastoma (MB), the most common malignant brain tumor in children. MB is associated with impaired differentiation of specific neural progenitors, suggesting that the deregulation of proteins involved in neural physiology could contribute to the transformed phenotype in MB. …”
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240
Impact of Childhood Cancer on Family Functioning and Family Quality of Life in the Western Region of Saudi Arabia
Published 2024-01-01“…Leukemia represents the highest disease prevalence followed by brain tumor. The highest score of the impact on the family survey was familial social concerns domains followed by financial burden with mean scores of 3.59 (98.8%) and 3.56 (98.0%), respectively. …”
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