A Critical Review of Constraint-Induced Movement Therapy and Forced Use in Children With Hemiplegia by Jeanne Charles, Andrew M. Gordon

“…Hemiplegia is a physical impairment that can occur in childhood following head trauma, cerebral vascular accident or transient ischemic attack (stroke), brain tumor, or congenital or perinatal injury. One of the most disabling symptoms of hemiplegia is unilaterally impaired hand and arm function. …”
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Radiation-Induced Growth Retardation and Microstructural and Metabolite Abnormalities in the Hippocampus by Shaefali P. Rodgers, Janice A. Zawaski, Iman Sahnoune, J. Leigh Leasure, M. Waleed Gaber

“…Cranial radiotherapy (CRT) increases survival in pediatric brain-tumor patients but can cause deleterious effects. …”
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In-depth inference of transcriptional regulatory networks reveals NPM1 as a therapeutic ribosomal regulator in MYC-amplified medulloblastoma by Tong Chen, Huiyao Chen, Mingyang Xia, Yunfei Liao, Hao Li, Xinran Dong, Yifeng Lin, Wenhao Zhou

“…Abstract Medulloblastoma (MB) is an aggressive pediatric brain tumor with distinct molecular heterogeneity. Identifying subtype-specific signatures within Group 3 and Group 4 remains challenging due to shared cytogenetic alterations and limitations of conventional differential gene expression analysis. …”
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The role of reaction temperature in synthesizing clove-derived copper oxide nanoparticles for brain cancer treatment by Mehrnoosh Fakhredin, Fatemeh Shariatmadar Tehrani, Maryam Aliannezhadi

“…Notably, CuO NPs obtained at a reaction temperature of 50°C exhibited better primary properties, facilitating their potential application in cancer treatment. Brain tumors constitute a disproportionately significant contributor to the overall cancer mortality burden, particularly in cases where surgical intervention is not a viable treatment option. …”
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In vivo MRI visualization of growth and morphology in the orthotopic xenotrasplantation U87 glioblastoma mouse SCID model by E. L. Zavjalov, I. A. Razumov, L. A. Gerlinskaya, A. V. Romashchenko

“…The study of tumor formation and the evaluation of new therapies for GBM require accurate and reproducible experimental brain tumor animal models. In this study we used MRI for investigation of tumor morphology and growth dynamic in an orthopic xenotransplantation immunodeficient mouse model (SCID mouse line). …”
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The Effect of SP/NK1R on the Expression and Activity of Catalase and Superoxide Dismutase in Glioblastoma Cancer Cells by Faranak Korfi, Hossein Javid, Reza Assaran Darban, Seyed Isaac Hashemy

“…Glioblastoma is the most malignant brain tumor with different therapeutic protocols, including surgery, radiotherapy, and chemotherapy. …”
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Multimodal Medical Image Fusion of Positron Emission Tomography and Magnetic Resonance Imaging Using Generative Adversarial Networks by R. Nandhini Abirami, P. M. Durai Raj Vincent, Kathiravan Srinivasan, K. Suresh Manic, Chuan-Yu Chang

“…Multimodal medical fusion of brain image helps to medical practitioners to simultaneously visualize hard portion like skull and soft portion like tissue. Brain tumor segmentation can be accurately performed by utilizing the image obtained after multimodal medical image fusion. …”
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MAP4 kinase-regulated reduced CLSTN1 expression in medulloblastoma is associated with increased invasiveness by Ece Sönmez, Shen Yan, Meng-Syuan Lin, Martin Baumgartner

“…Abstract De-regulated protein expression contributes to tumor growth and progression in medulloblastoma (MB), the most common malignant brain tumor in children. MB is associated with impaired differentiation of specific neural progenitors, suggesting that the deregulation of proteins involved in neural physiology could contribute to the transformed phenotype in MB. …”
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Comprehensive Analysis Identifies <i>THEMIS2</i> as a Potential Prognostic and Immunological Biomarker in Glioblastoma by Jianan Chen, Qiong Wu, Anders E. Berglund, Robert J. Macaulay, Arnold B. Etame

“…Glioblastoma (GBM) is a highly aggressive brain tumor characterized by its ability to evade the immune system, hindering the efficacy of current immunotherapies. …”
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Cinnamaldehyde impacts key cellular signaling pathways for induction of programmed cell death in high-grade and low-grade human glioma cells by Yoo Na Kim, Ketki Patil, S. Balakrishna Pai

“…Abstract Objective Primary tumors of the brain and a large percent of malignant brain tumors are gliomas. Gliomas comprise high-grade gliomas like glioblastoma multiforme (GBMs), many of which have mutation in the tumor suppressor p53 gene and low-grade gliomas (LGGs). …”
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Impact of Childhood Cancer on Family Functioning and Family Quality of Life in the Western Region of Saudi Arabia by Tagwa Yousif Omer

“…Leukemia represents the highest disease prevalence followed by brain tumor. The highest score of the impact on the family survey was familial social concerns domains followed by financial burden with mean scores of 3.59 (98.8%) and 3.56 (98.0%), respectively. …”
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The doppel (Dpl) Protein Influences In Vitro Migration Capability in Astrocytoma-Derived Cells by Alberto Azzalin, Elena Sbalchiero, Giulia Barbieri, Silvia Palumbo, Cristina Muzzini, Sergio Comincini

“…Recently, the protein has been described to be ectopically expressed in astrocytomas and its potential association to the brain tumor malignancy progression has been advanced. …”
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Synergism of d-limonene and temozolomide on migratory and apoptotic behaviors of human glioblastoma cell lines by Megha Gautam, Reema Gabrani

“…Introduction: Glioblastoma (GBM), which is a heterogeneous and aggressive type of brain tumor, is known for its poor survival outcomes. …”
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Deciphering the dose-dependent effects of thymoquinone on cellular proliferation and transcriptomic changes in A172 glioblastoma cells. by Rachana Pandey, Purushothaman Natarajan, Umesh K Reddy, Wei Du, Cristian Sirbu, Moussa Sissoko, Gerald R Hankins

“…Glioblastoma multiforme (GBM), the most prevalent primary malignant brain tumor in adults, exhibits a dismal 6.9% five-year survival rate post-diagnosis. …”
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Nootkatone inhibits the progression of glioblastoma by activating the ATF4-CHOP-CHAC1 pathway by Qian Wang, Xiumin Xue, Zhichao Chen, Wei Zhang, Yiming Qian, Danni Chen, Lin Lin, Yinfeng Yuan, Weiqiao Zhao, Zhihui Huang, Yongjie Wang

“…Abstract Glioblastoma multiforme (GBM) represents a primary brain tumor that is widely prevalent, and clinical drugs available for its treatment exhibit varying degrees of resistance. …”
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Comparative Analysis of Edge Detection Operators Using a Threshold Estimation Approach on Medical Noisy Images with Different Complexities by Vladimir Maksimovic, Branimir Jaksic, Mirko Milosevic, Jelena Todorovic, Lazar Mosurovic

“…This study focuses on medical images from three distinct datasets: retinal images, brain tumor segmentation, and lung segmentation from CT scans. …”
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Malignant Glioma in the Cerebellum Presenting as Multiple Small Lesions by Takashi Mamiya, Shinji Shimato, Toshihisa Nishizawa, Takashi Yamanouchi, Kojiro Ishikawa, Makoto Ito, Masato Abe, Kyozo Kato

“…Malignant glioma, the most common malignant primary brain tumor in adults, usually occurs in supratentorial space as a single mass lesion, and cerebellar location and multiple appearance are uncommon. …”
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Nanoparticle-in-Hydrogel Delivery System for the Sequential Release of Two Drugs by Demian van Straten, Jaime Fernández Bimbo, Wim E. Hennink, Tina Vermonden, Raymond M. Schiffelers

“…Background/Objectives: Glioblastoma is the most common and lethal primary brain tumor. Patients often suffer from tumor- and treatment induced vasogenic edema, with devastating neurological consequences. …”
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Development of a New Reporter Gene System-dsRed/Xanthine Phosphoribosyltransferase-Xanthine for Molecular Imaging of Processes Behind the Intact Blood-Brain Barrier by Mikhail Doubrovin, Vladimir Ponomarev, Inna Serganova, Suren Soghomonian, Tadashi Myagawa, Tatiana Beresten, Lyudmila Ageyeva, Michel Sadelain, Jason Koutcher, Ronald G Blasberg, Juri G. Gelovani Tjuvajev

“…The accumulation in vivo in the transfected flank tumor was to 2.4 ± 0.3% dose/g, compared to 0.78 ± 0.02% dose/g and 0.64 ± 0.05% dose/g in the control flank tumors and intact muscle, respectively. [ 14 C]-Xanthine appeared to be capable of specific accumulation in the transfected infiltrative brain tumor (RG2-dsRed/XPRT), which corresponded to the 585 nm fluorescent signal obtained from the adjacent cryosections. …”
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A realistic human head phantom for electromagnetic detection of brain diseases by Zelin Bai, Diyou Chen, Ke Ma, Gui Jin, Jinlong Qiu, Quanquan Li, Haocheng Li, Mingsheng Chen

“…It proved valuable for studying the distribution of electromagnetic fields in the human head and for investigating novel electromagnetic detection techniques exploiting brain tissue dielectric properties. (4) The created physical model and the numerical model were derived from the same person, which provided a good continuity between simulation experiments and physical experiments, and provided a realistic verification platform for the research of electromagnetic detection technology for brain diseases, such as differentiating the kind of stroke, monitoring brain edema, brain tumor microwave imaging, and diagnosis of Alzheimer’s disease.…”
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