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141
Multiple Extracranial Metastases from Primary Gliosarcoma in a Patient with Two Previous Different Primary Cancers
Published 2019-01-01“…Gliosarcoma (GS) constitutes a minor fraction of primary glioblastoma (GBM), which is the most frequent malignant brain tumor in adults. Despite the fact that malignant gliomas are highly invasive, extracranial metastases are very rarely seen, and the mechanisms behind extracranial dissemination are still unclarified. …”
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142
Analysis of Circulating Plasma MicroRNA Profile in Low-Grade and High-Grade Glioma – A Cross-Sectional Study [version 1; peer review: 2 approved, 1 approved with reservations, 1 no...
Published 2024-11-01“…Background Glioma is the second most common type of brain tumor, accounting for 24% of all brain tumor cases. …”
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143
Recent Advances of the NLRP3 Inflammasome in Central Nervous System Disorders
Published 2016-01-01“…In addition, we summarize the recent researches on the role of NLRP3 inflammasome in central nervous system (CNS) diseases, including traumatic brain injury, ischemic stroke and hemorrhagic stroke, brain tumor, neurodegenerative diseases, and other CNS diseases. …”
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144
New Immunotherapeutic Approaches for Glioblastoma
Published 2021-01-01“…Glioblastoma (GBM) is the most common primary malignant brain tumor with a high mortality rate. The current treatment consists of surgical resection, radiation, and chemotherapy; however, the median survival rate is only 12–18 months despite these alternatives, highlighting the urgent need to find new strategies. …”
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145
Advancements in the Use of Hydrogels for Regenerative Medicine: Properties and Biomedical Applications
Published 2022-01-01“…Hydrogels represent a potential alternative to regenerating tissue lost after removing a brain tumor and/or brain injuries. This reason presents them as an exciting alternative to highly complex human physiological problems, such as injuries to the central nervous system and neurodegenerative disease.…”
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146
Glioblastoma. Past, present and future
Published 2024-07-01“…<p>Glioblastoma is the most advanced, common and malignant stage of primary brain tumors in adults. It represents about 57% of all glial tumors. …”
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147
Gene Therapy for Glioblastoma Multiforme
Published 2025-01-01“…Glioblastoma multiforme (GBM) is a devastating, aggressive primary brain tumor with poor patient outcomes and a five-year survival of less than 10%. …”
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148
Glioblastoma Multiforme Stem Cells
Published 2011-01-01“…Glioblastoma multiforme (GBM) is an aggressive, malignant, and lethal brain tumor, resistant to all current forms of treatment. …”
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149
Anticancer effects of ABTL0812, a clinical stage drug inducer of autophagy-mediated cancer cell death, in glioblastoma models
Published 2022-11-01“…BackgroundGlioblastoma multiforme (GBM) is the most malignant adult brain tumor. Current standard of care treatments have very limited efficacy, being the patients´ overall survival 14 months and the 2-year survival rate less than 10%. …”
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150
Comparative analysis of pediatric SHH medulloblastoma DAOY spheres and adherent monolayers: implications for medulloblastoma research
Published 2025-01-01“…Abstract Medulloblastoma, the most prevalent brain tumor among children, requires a comprehensive understanding of its cellular characteristics for effective research and treatment. …”
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151
Toxic Epidermal Necrolysis Associated with Antiepileptic Drugs and Cranial Radiation Therapy
Published 2013-01-01“…Although TEN is a rare toxicity, physicians should pay a special attention to the monitoring of brain tumor patients on antiepileptic prophylaxis during cranial irradiation; furthermore, patients should be counselled to notify their physicians if they develop any new or unusual symptoms.…”
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152
Glioma Stem Cells: Signaling, Microenvironment, and Therapy
Published 2016-01-01“…Glioblastoma remains the most common and devastating primary brain tumor despite maximal therapy with surgery, chemotherapy, and radiation. …”
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153
Brain gliomas new transcriptomic discoveries from differentially expressed genes to therapeutic targets
Published 2025-01-01“…Abstract Gliomas are a prevalent form of primary malignant brain tumor, yet the intricate molecular mechanisms underlying its pathogenesis remain unclear. …”
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154
PLIN1 suppresses glioma progression through regulating lipid metabolism
Published 2025-01-01“…Abstract Glioma is a common and destructive brain tumor, which is highly heterogeneous with poor prognosis. …”
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155
Brain Midline Shift Measurement and Its Automation: A Review of Techniques and Algorithms
Published 2018-01-01“…Shift of midline intracranial structures helps diagnosing intracranial lesions, especially traumatic brain injury, stroke, brain tumor, and abscess. Being a sign of increased intracranial pressure, MLS is also an indicator of reduced brain perfusion caused by an intracranial mass or mass effect. …”
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156
Brain CT image classification based on mask RCNN and attention mechanism
Published 2024-11-01“…The application of machine learning, and block-chain techniques into medical image retrieval, classification and auxiliary diagnosis has become one of the research hotspots at present. Brain tumor is one of the major diseases threatening human life. …”
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157
LncRNA-PVT1 enhances glucose metabolism of pediatric low-grade glioma cells through sponging miR-187-3p
Published 2024-12-01“…Studies have revealed critical roles of long non-coding RNAs (lncRNAs) in brain tumor progressions. Here, we aimed to investigate the clinical roles and molecular mechanisms of lncRNA PVT1 in PLGG. …”
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158
Discontiguous recurrences of IDH-wildtype glioblastoma share a common origin with the initial tumor and are frequently hypermutated
Published 2025-01-01“…Abstract Glioblastoma is the deadliest primary brain tumor, largely due to inevitable recurrence of the disease after treatment. …”
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159
Application of Multifunctional Metal Nanoparticles in the Treatment of Glioma
Published 2025-01-01“…Yanhong Ren,1,2,* Han Yang,3,* Duo Xu,4 Zhengkui Zhang,4 Shangfeng Gao,1,4 Rutong Yu1,4 1Department of Neurosurgery, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, 221002, People’s Republic of China; 2Beijing Institute of Brain Disorders, Capital Medical University, Beijing, 100069, People’s Republic of China; 3Department of Neurology, The First Hospital of Changsha, Changsha, 410008, People’s Republic of China; 4Institute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, Jiangsu, 221002, People’s Republic of China*These authors contributed equally to this workCorrespondence: Shangfeng Gao; Rutong Yu, Email gaoshangfeng@xzhmu.edu.cn; rtyu@xzhmu.edu.cnAbstract: Glioma is the most common primary malignant brain tumor with a poor survival rate. It is characterized by diffuse and invasive growth and heterogeneity, which limits tumor identification and complete resection. …”
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160
Identification of CDKN3 overexpression as a marker of poor prognosis and potential therapeutic target in low-grade glioma
Published 2025-01-01“…Abstract Low-grade glioma (LGG) is a primary, slow-growing brain tumor; however, its treatment and prognosis remain challenging. …”
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