COVID-19 infection: neurological symptoms and encephalitis by A. Jasionis, R. Mameniškienė

“…This article discusses published data on neurological manifestations of COVID-19 and their possible explanation, and presents reported encephalitis cases. Brain injury caused by other coronaviruses is also examined. …”
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Outcomes and predictors of unplanned intensive care unit admission for pediatric trauma patients by Tyler Liang, MD, Areg Grigorian, MD, Robert Painter, MD, James Jeng, MD, Theresa Chin, MD, Laura F. Goodman, MD MPH, Yigit S. Guner, MD, Catherine Kuza, MD, Jeffry Nahmias, MD MHPE

“…Significant predictors of UIA include ureteral, esophageal and brain injury.…”
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Protective effects of wogonin in the treatment of central nervous system and degenerative diseases by Qingan Fu, Qingyun Yu, Hongdan Luo, Zhekang Liu, Xiaowei Ma, Huijian Wang, Zhijuan Cheng

“…This review elucidates the pharmacological mechanisms underlying the protective effects of wogonin in CNS diseases, including ischemic stroke, hemorrhagic stroke, traumatic brain injury, epilepsy, anxiety, neurodegenerative diseases, and CNS infections. …”
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The transcriptional response of cortical neurons to concussion reveals divergent fates after injury by Mor R. Alkaslasi, Eliza Y. H. Lloyd, Austin S. Gable, Hanna Silberberg, Hector E. Yarur, Valerie S. Tsai, Mira Sohn, Gennady Margolin, Hugo A. Tejeda, Claire E. Le Pichon

“…Abstract Traumatic brain injury (TBI) is a risk factor for neurodegeneration, however little is known about how this kind of injury alters neuron subtypes. …”
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GABAB receptors regulate the neural stem cell potential of Pkd2l1+ cerebrospinal fluid-contacting neurons via the PI3K/Akt signaling pathway by Liang Cao, Wei-Hong Yan, Wenjun Pi, Yi Zhang, Yan-Xiang Xiong, V. Wee Yong, Mengzhou Xue, Qing Li, Chunfu Zheng, Leiluo Yang

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Protocol for a living systematic review for the management of concussion in adults by Mark Bayley, Diana Velikonja, Shawn Marshall, Alexander Lithopoulos, Dorothyann Curran, Lisa Fischer, Christopher Knee, Julia Lauzon, Margaret Nevison

“…Introduction Concussion/mild traumatic brain injury (mTBI) often presents initially with disabling symptoms that resolve, but for an unfortunate minority some of these symptoms may become prolonged. …”
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Sequencing and Integration of Cervical Manual Therapy and Vestibulo-oculomotor Therapy for Concussion Symptoms: Retrospective Analysis by Christopher Kevin Wong, Lauren Ziaks, Samantha Vargas, Tessia DeMattos, Chelsea Brown

“…# Background After concussion many people have cervicogenic headache, visual dysfunction, and vestibular deficits that can be attributed to brain injury, cervical injury, or both. While clinical practice guidelines outline treatments to address the symptoms that arise from the multiple involved systems, no preferred treatment sequence for post-concussion syndrome has emerged…”
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Postictal Psychosis: Case Report and Literature Review by Joana Regala, João Lourenço, Francisco Moniz-Pereira, António Bento

“…Additionally, she had previous cognitive impairment and encephalomalacia in the right parietooccipital region as a sequela of a moderate-to-severe traumatic brain injury known to precede the emergence of the epilepsy. …”
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Community Integration of Disability: A Bibliometric and Knowledge-Map Analysis by Wang S, Li D, Liu C, Sun X, Shi Y, Wang H, Zhang H

“…The three most frequent keywords is Brain Injury (571, 13%), Individuals (488, 11%), Quality of Life (434, 10%). …”
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Acquired Hemophilia A with a Rare Presentation of Acute Subdural Hematoma by Yoshihide Sehara, Yuka Hayashi, Jun Mimuro

“…An 80-year-old man was admitted for acute subdural hematoma caused by a mild brain injury. His coagulation test showed an isolated prolongation of activated partial thromboplastin time (aPTT). …”
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Current Controversies in Newer Therapies to Treat Birth Asphyxia by Pia Wintermark

“…Unfortunately, this neuroprotective strategy seems efficient in preventing brain injury in some asphyxiated newborns, but not in all of them. …”
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Understanding the Mechanisms of Recovery and/or Compensation following Injury by Michael J. Hylin, Abigail L. Kerr, Ryan Holden

“…Injury due to stroke and traumatic brain injury result in significant long-term effects upon behavioral functioning. …”
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Risen Alive: The Lazarus Phenomenon by Waqar Haider Gaba, Shahad Abobakar El Hag, Shaima Mustafa Bashir

“…The patient survived; however, she developed significant neurological deficits secondary to prolonged anoxic brain injury. She was discharged after a ten-week stay in the hospital but did not achieve full neurologic, cognitive, and motor recovery. …”
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IGF-1 impacts neocortical interneuron connectivity in epileptic spasm generation and resolution by Carlos J. Ballester-Rosado, John T. Le, Trang T. Lam, Anne E. Anderson, James D. Frost, Jr., John W. Swann

“…Little is known about the mechanisms that generate epileptic spasms following perinatal brain injury. Recent studies have implicated reduced levels of Insulin-like Growth Factor 1 (IGF-1) in these patients’ brains. …”
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The Rise of Inflow Cisternostomy in Resource-Limited Settings: Rationale, Limitations, and Future Challenges by Ulrick Sidney Kanmounye

“…Low- and middle-income countries (LMICs) bear most of the global burden of traumatic brain injury (TBI), but they lack the resources to address this public health crisis. …”
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Terson’s syndrome: An interesting case report by Rajwinder Kaur, Mehak Mangla, Balbir Khan, Harleen Kaur

“…Terson’s syndrome is described as an intra-ocular hemorrhage (sub hyaloid, intraretinal, subretinal bleed, or vitreous) occurring secondary to raised intracranial pressure (ICP) secondary to any intra cranial hemorrhage or traumatic brain injury. This report presents a case of a 34-year-old male who was diagnosed with a ruptured aneurysm of the left middle cerebral artery, which led to intracranial hemorrhage followed by raised ICP. …”
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P2Y Receptors in Synaptic Transmission and Plasticity: Therapeutic Potential in Cognitive Dysfunction by Segundo J. Guzman, Zoltan Gerevich

“…The findings discussed here may explain how P2Y1 receptor activation during brain injury, hypoxia, inflammation, schizophrenia, or Alzheimer’s disease leads to an impairment of cognitive processes. …”
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Purinergic Receptors of the Central Nervous System: Biology, PET Ligands, and Their Applications by Hamideh Zarrinmayeh PhD, Paul R. Territo PhD

“…Based on their endogenous ligands, purinergic receptors are classified into P1 or adenosine, P2X and P2Y receptors. During brain injury or under pathological conditions, rapid diffusion of extracellular adenosine triphosphate (ATP) or uridine triphosphate (UTP) from the damaged cells, promote microglial activation that result in the changes in expression of several of these receptors in the brain. …”
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An open window: the crucial role of the gut-brain axis in neurodevelopmental outcomes post-neurocritical illness by Victoria Ronan

“…The most common diagnoses for a neurocritical illness admission include traumatic brain injury, status epilepticus, post-cardiac arrest, hypoxic ischemic encephalopathy, meningo/encephalitis, and stroke. …”
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Beyond the Hit: The Hidden Costs of Repetitive Head Trauma by Sikandar Khan, Lora Talley

“…While impact-reducing techniques have shown some efficacy in decreasing brain injury incidence, proper tackling techniques, such as “heads-up play,” also play a vital role in minimizing risk. …”
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