Optimization of TMS target engagement: current state and future perspectives by Pantelis Lioumis, Pantelis Lioumis, Pantelis Lioumis, Timo Roine, Timo Roine, Ida Granö, Dogu Baran Aydogan, Dogu Baran Aydogan, Elena Ukharova, Victor H. Souza, Dubravko Kičić, Risto J. Ilmoniemi, Nikos Makris, Nikos Makris, Nikos Makris, Nikos Makris

Subjects: “…neurophysiological signatures of brain circuits…”
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Personalised transcranial magnetic stimulation for treatment-resistant depression, depression with comorbid anxiety and negative symptoms of schizophrenia: a narrative review by Xiao Wei Tan, Hasvinjit Kaur Gulwant Singh, Jovi Zheng Jie Koh, Rachel Si Yun Tan, Phern Chern Tor

“…Nonetheless, symptom-specific brain circuit targeting has not been tested prospectively. …”
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Relationship between Zinc (Zn2+) and Glutamate Receptors in the Processes Underlying Neurodegeneration by Bartłomiej Pochwat, Gabriel Nowak, Bernadeta Szewczyk

“…The results from numerous studies have shown that an imbalance between particular neurotransmitters may lead to brain circuit dysfunction and development of many pathological states. …”
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Circuitry and Synaptic Dysfunction in Alzheimer’s Disease: A New Tau Hypothesis by Siddhartha Mondragón-Rodríguez, Humberto Salgado-Burgos, Fernando Peña-Ortega

“…Additionally, we will briefly address the role of brain circuit alterations as a potential biomarker for detecting the prodromal AD stage.…”
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Increased N-Ethylmaleimide-Sensitive Factor Expression in Amygdala and Perirhinal Cortex during Habituation of Taste Neophobia by Beatriz Gómez-Chacón, Fernando Gámiz, Thomas C. Foster, Milagros Gallo

“…The results suggest the relevance of a potential network in the temporal lobe for taste recognition memory and open new possibilities for understanding the molecular mechanisms mediating the impact of sensory experience on brain circuit function.…”
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Clinical and Biochemical Manifestations of Depression: Relation to the Neurobiology of Stress by Phillip W. Gold, Rodrigo Machado-Vieira, Maria G. Pavlatou

“…Aspects such as depression subtypes, inflammation, insulin resistance, oxidative stress, and prothrombotic states in critical brain circuits and periphery are critically appraised. …”
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The Many Forms and Functions of Long Term Plasticity at GABAergic Synapses by Arianna Maffei

“…Thus, the understanding of inhibitory synaptic plasticity is crucial to fully comprehend the physiology of brain circuits. Here, I will review recent findings about plasticity at GABAergic synapses and discuss how it may contribute to circuit function.…”
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Potential common targets of music therapy intervention in neuropsychiatric disorders: the prefrontal cortex-hippocampus -amygdala circuit (a review) by Yuqin Dan, Ying Xiong, Danghan Xu, Yuqi Wang, Meng Yin, Pengwei Sun, Yi Ding, Ziyun Feng, Peng Sun, Weili Xia, Gongchang Yu, Gongchang Yu, Li Li, Li Li

“…Multiple neuropsychiatric disorders share the same mental and somatic dysfunction and may involve common brain circuits and mechanistic targets. Music therapy, as an art form with proven efficacy, low cost and few side effects, is promoted for use in interventions for neuropsychiatric disorders. …”
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Synaptic plasticity in fronto-insular circuits underlying stress susceptibility and resilience by Devin Rocks, Conor Liston

“…In this review, we examine how chronic stress and antidepressants modulate synaptic connectivity in stress-sensitive brain circuits. We discuss the roles of various synaptic and molecular pathways in these processes, their interaction with circadian rhythms, and their contributions to the regulation of mood, with a particular focus on anhedonia. …”
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Optimizing a Rodent Model of Parkinson's Disease for Exploring the Effects and Mechanisms of Deep Brain Stimulation by Karl Nowak, Eilhard Mix, Jan Gimsa, Ulf Strauss, Kiran Kumar Sriperumbudur, Reiner Benecke, Ulrike Gimsa

“…Further progress depends on a deeper insight into the mechanisms of action of DBS in the context of disturbed brain circuits. For this, optimized animal models have to be developed. …”
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Musician’s dystonia: a perspective on the strongest evidence towards new prevention and mitigation treatments by Joy Grifoni, Joy Grifoni, Valeria Crispiatico, Anna Castagna, Rosa Maria Converti, Marina Ramella, Angelo Quartarone, Teresa L’Abbate, Teresa L’Abbate, Karolina Armonaite, Karolina Armonaite, Luca Paulon, Luca Paulon, Francescaroberta Panuccio, Franca Tecchio

“…Theoretically, MD is explored as a result of impaired sensorimotor interplay across different brain circuits, supported by the most frequently cited scientific evidence—each referenced dozens of times in Scopus. …”
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The role of the hippocampus in working memory and word reading: Novel neural correlates of reading among youth living in the context of economic disadvantage by ET. Marcelle, H. Yang, JW. Cohen, B. Ramphal, D. Pagliaccio, V. Rauh, BS. Peterson, F. Perera, H. Andrews, AG. Rundle, J. Herbstman, AE. Margolis

“…This finding suggests that other brain circuits may underlie reading in these youth. A hippocampal circuit is one likely candidate, as it has recently been shown to support domain-general processes like working memory (WM) that are also associated with reading. …”
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Neural Determinants of Sedentary Lifestyle in Older Adults: A Brain Network Analysis by Mohsen Bahrami, Jonathan H Burdette, Paul J Laurienti, Barbara J Nicklas, W Jack Rejeski, Jason Fanning

“…Method The goal of the current study, using baseline fMRI and accelerometry data from 36 participants and advanced machine learning tools, was to determine if we could identify complex brain circuits underlying variability associated with changes in sitting time and daily steps during the 6‐month intensive phase among participants randomized to the WL + SitLess treatment condition. …”
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Subtle changes in Purkinje cell firing in Purkinje cell-specific Dyt1 ΔGAG knock-in mice by Hong Xing, Pallavi Girdhar, Yuning Liu, Fumiaki Yokoi, David E. Vaillancourt, Yuqing Li

“…Our results suggest that the abnormal Purkinje cell firing in the global KI mice was not cell-autonomous and was caused by physiological changes elsewhere in the brain circuits. Our results also contribute to the ongoing research of how basal ganglia and cerebellum interact to influence motor control in normal states and movement disorders.…”
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Lipids and C-reactive protein predict anhedonia and reward circuit functional connectivity responses to anti-cytokine and dopaminergic therapies in patients with depression by Aditya Singh, Mandakh Bekhbat, David R. Goldsmith, Ngoc-Anh Le, Evanthia C. Wommack, Zhihao Li, Ebrahim Haroon, Jennifer C. Felger

“…Increased inflammation and associated metabolic disturbances have been shown to affect neurotransmitters and brain circuits, contributing to an immunometabolic phenotype of anhedonic depression. …”
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