Association between urinary cobalt exposure and kidney stones in U.S. adult population: results from the National Health and Nutrition Examination Survey by Jun Lu, Dongmei Hong, Qian Wu, Yinghui Xia, Guozhong Chen, Tie Zhou, Cheng Li

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Distinct changes to hippocampal and medial entorhinal circuits emerge across the progression of cognitive deficits in epilepsy by Yu Feng, Keziah S. Diego, Zhe Dong, Zoé Christenson Wick, Lucia Page-Harley, Veronica Page-Harley, Julia Schnipper, Sophia I. Lamsifer, Zachary T. Pennington, Lauren M. Vetere, Paul A. Philipsberg, Ivan Soler, Albert Jurkowski, Christin J. Rosado, Nadia N. Khan, Denise J. Cai, Tristan Shuman

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OLIG2 mediates a rare targetable stem cell fate transition in sonic hedgehog medulloblastoma by Kinjal Desai, Siyi Wanggou, Erika Luis, Heather Whetstone, Chunying Yu, Robert J. Vanner, Hayden J. Selvadurai, Lilian Lee, Jinchu Vijay, Julia E. Jaramillo, Jerry Fan, Paul Guilhamon, Michelle Kushida, Xuejun Li, Gregory Stein, Santosh Kesari, Benjamin D. Simons, Xi Huang, Peter B. Dirks

“…Previously, we demonstrated that the growth of the paediatric brain malignancy, sonic hedgehog subgroup medulloblastoma, is rooted in a dysregulated developmental hierarchy, the apex of which is defined by characteristically quiescent SOX2+ stem-like cells. …”
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Mapping and modeling age-related changes in intrinsic neural timescales by Kaichao Wu, Leonardo L. Gollo

“…Abstract Intrinsic timescales of brain regions exhibit heterogeneity, escalating with hierarchical levels, and are crucial for the temporal integration of external stimuli. …”
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Evaluating the effectiveness of integrated traditional Chinese and Western treatment based on symptom grading: a study protocol for a multi-center, randomized controlled trial of p... by Jiaxi Mai, Tingwei Zhou, Tingwei Zhou, Tingwei Zhou, Chen Wang, Chen Wang, Junrong Ye, Junrong Ye, Jiao Chen, Jiao Chen, Jiao Chen, Wen Wang, Wen Wang, Wen Wang, Yuanxin Pan, Yuanxin Pan, Yuanxin Pan, Yanheng Wei, Yanheng Wei, Lexin Yuan, Lexin Yuan, Hang Yang, Hang Yang, Shengwei Wu, Shengwei Wu, Jianxiong Guo, Jianxiong Guo, Jianxiong Guo, Aixiang Xiao, Aixiang Xiao, Aixiang Xiao

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Distinct mechanisms of electroacupuncture and manual acupuncture in modulating hypothalamic GnRH–tanycyte unit function of polycystic ovary syndrome by Yu Wang, Yicong Wang, Yuning Chen, Wenhan Lu, Xiaoyu Tong, Jiajia Li, Wenhao Gao, Rui Huang, Wei Hu, Yi Feng

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Reduced frontotemporal connectivity during a verbal fluency task in patients with anxiety, sleep, and major depressive disorders by Fanxi Ding, Yiyang Ying, Yuqing Jin, Xuanru Guo, Xuanru Guo, You Xu, Zhenghe Yu, Haiteng Jiang, Haiteng Jiang, Haiteng Jiang

“…Furthermore, clarifying the mechanisms underlying variations in executive function impairments across multiple psychiatric disorders will enhance our comprehension of brain activity alternations among these disorders. …”
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Systematic dissection of pleiotropic loci and critical regulons in excitatory neurons and microglia relevant to neuropsychiatric and ocular diseases by Yunlong Ma, Dingping Jiang, Jingjing Li, Gongwei Zheng, Yao Deng, Xuanxuan Gou, Shuaishuai Gao, Cheng Chen, Yijun Zhou, Yaru Zhang, Chunyu Deng, Yinghao Yao, Haijun Han, Jianzhong Su

“…To investigate the biological connections between the eye and brain, we integrated bulk and single-cell multiomic profiles with GWAS summary statistics for eight neuropsychiatric and five ocular diseases. …”
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Stem Cell Tracking Technologies for Neurological Regenerative Medicine Purposes by Yongtao Zheng, Jiongwei Huang, Tongming Zhu, Ronggang Li, Zhifu Wang, Fukai Ma, Jianhong Zhu

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Construction of a Multimodal Neuroimaging Data Fusion System and Evaluation of Mental Fatigue Using Nonlinear Analysis by Rui Chen, Zhenzhong Li, Yi Lai

“…Based on the binary and the weighted brain function networks, the relationship between the human brain fatigue and the brain function network is evaluated by calculating the fractal dimension. …”
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Altered Functional Connectivity after Epileptic Seizure Revealed by Scalp EEG by Yi Liang, Chunli Chen, Fali Li, Dezhong Yao, Peng Xu, Liang Yu

“…Epileptic seizures are considered to be a brain network dysfunction, and chronic recurrent seizures can cause severe brain damage. …”
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Rh-relaxin-2 attenuates oxidative stress and neuronal apoptosis via ERK-nNOS-NO pathway after germinal matrix hemorrhage in rats by Jun Liu, Yonghua Cai, Khalil ur Rahman, Qixiong Zhou, Guangjie Liu, Huibin Kang, Mingzhou Li, Shichao Zhang, Gang Wang, Wenfeng Feng, Xi’an Zhang, Guozhong Zhang, Ye Song, Peng Li

“…Lenti-virus with sgRXFP1 and sgCtrl was administered intracerebroventricular (i.c.v.) on the left side of the brain to inhibit the RXFP1 at 2d prior to GMH induction, and LY321499, ERK inhibitor, was administered by i.c.v. injection at 1 h on the left side of the brain prior to GMH induction, respectively. …”
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Homeostasis and metabolism of iron and other metal ions in neurodegenerative diseases by Leilei Chen, Qingqing Shen, Yingjuan Liu, Yunqi Zhang, Liping Sun, Xizhen Ma, Ning Song, Junxia Xie

“…Abstract As essential micronutrients, metal ions such as iron, manganese, copper, and zinc, are required for a wide range of physiological processes in the brain. However, an imbalance in metal ions, whether excessive or insufficient, is detrimental and can contribute to neuronal death through oxidative stress, ferroptosis, cuproptosis, cell senescence, or neuroinflammation. …”
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Loss of MEF2C function by enhancer mutation leads to neuronal mitochondria dysfunction and motor deficits in mice by Ali Yousefian-Jazi, Suhyun Kim, Jiyeon Chu, Seung-Hye Choi, Phuong Thi Thanh Nguyen, Uiyeol Park, Min-gyeong Kim, Hongik Hwang, Kyungeun Lee, Yeyun Kim, Seung Jae Hyeon, Hyewhon Rhim, Hannah L. Ryu, Grewo Lim, Thor D. Stein, Kayeong Lim, Hoon Ryu, Junghee Lee

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Chorea as the First Sign in a Patient with Elderly-Onset Systemic Lupus Erythematosus by Yuko Ariizumi, Tetsutaro Ozawa, Takayoshi Tokutake, Izumi Kawachi, Masaki Hirose, Shinichi Katada, Shuichi Igarashi, Keiko Tanaka, Masatoyo Nishizawa

“…Magnetic resonance imaging (MRI) of the brain demonstrated a focal lesion in the right caudate head, which showed hyperintensity on fluid-attenuated inversion recovery and diffusion-weighted imaging. …”
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Vaccine-induced T cell receptor T cell therapy targeting a glioblastoma stemness antigen by Yu-Chan Chih, Amelie C. Dietsch, Philipp Koopmann, Xiujian Ma, Dennis A. Agardy, Binghao Zhao, Alice De Roia, Alexandros Kourtesakis, Michael Kilian, Christopher Krämer, Abigail K. Suwala, Miriam Stenzinger, Halvard Boenig, Agnieszka Blum, Victor Murcia Pienkowski, Kuralay Aman, Jonas P. Becker, Henrike Feldmann, Theresa Bunse, Richard Harbottle, Angelika B. Riemer, Hai-Kun Liu, Nima Etminan, Felix Sahm, Miriam Ratliff, Wolfgang Wick, Michael Platten, Edward W. Green, Lukas Bunse

“…Single-cell sequencing of primary brain tumors shows PTPRZ1 overexpression in malignant cells, especially in glioblastoma stem cells (GSCs) and astrocyte-like cells. …”
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Impact of childhood trauma on cognitive function in patients with bipolar disorder by Zhiyang Zhang, Zhiyang Zhang, Chenyu Zhou, Chenyu Zhou, Zhen Mao, Zhen Mao, Yue Sun, Yue Sun, Lei Zhao, Lei Zhao, Tian Li, Tian Li, Chuanyue Wang, Chuanyue Wang, Qijing Bo, Qijing Bo

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Neuroimaging stratification reveals the striatal vulnerability to stress as a risk for schizophrenia by Xiaoqian Ma, Nana Feng, Lena Palaniyappan, Luolong Cao, Zixin Gu, Jujiao Kang, Liu Yuan, Lijun Ouyang, Yujue Wang, Chunwang Li, Ke Jin, Xiaogang Chen, Jianfeng Feng, Ying He, Qiang Luo

“…Abstract The striatum, a core brain structure relevant for schizophrenia, exhibits heterogeneous volumetric changes in this illness. …”
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Sporadic ALS hiPSC-derived motor neurons show axonal defects linked to altered axon guidance pathways by Lisha Ye, Katarina Stoklund Dittlau, Adria Sicart, Rekin'’s Janky, Philip Van Damme, Ludo Van Den Bosch

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Effective Connectivity Study Guiding the Neuromodulation Intervention in Figurative Language Comprehension Using Optical Neuroimaging by Tania Alexandra Couto, Shiyang Xu, Paulo Armada da Silva, Chenggang Wu, Karl Neergaard, Meng-Yun Wang, Juan Zhang, Yutao Xiang, Zhen Yuan

“…The current study is aimed at establishing links between brain network examination and neural plasticity studies measured by optical neuroimaging. …”
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