Increasing brain half-life of antibodies by additional binding to myelin oligodendrocyte glycoprotein, a CNS specific protein by Marie-Lynn Cuypers, Tom Jaspers, Jarne Clerckx, Simon Leekens, Christopher Cawthorne, Guy Bormans, Frederik Cleeren, Nick Geukens, Bart De Strooper, Maarten Dewilde

Subjects: “…Blood–brain barrier…”
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Glycogen Synthase Kinase-3 Regulates Production of Amyloid-β Peptides and Tau Phosphorylation in Diabetic Rat Brain by Zhong-Sen Qu, Liang Li, Xiao-Jiang Sun, Yu-Wu Zhao, Jin Zhang, Zhi Geng, Jian-Liang Fu, Qing-Guo Ren

“…Taken together, our studies suggest that GSK-3 regulates both the production of Aβ and the phosphorylation of tau in rat brain and may therefore contribute to DM caused AD-like neurological defects.…”
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Intraoperative vascular anastomosis occlusion due to cold agglutinin disease during brain surgery: a case report by Kazuma Kitamura, Mayumi Nakanishi, Naokazu Fukuoka, Kumiko Tanabe, Yoshinori Kamiya

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Developing a brain inspired multilobar neural networks architecture for rapidly and accurately estimating concrete compressive strength by Bashar Alibrahim, Ahed Habib, Maan Habib

“…In order to address these limitations, this study introduces a novel multi-lobar artificial neural network (MLANN) architecture inspired by the brain’s lobar processing of sensory information, aiming to improve the accuracy and efficiency of estimating concrete compressive strength. …”
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Enhanced multiscale human brain imaging by semi-supervised digital staining and serial sectioning optical coherence tomography by Shiyi Cheng, Shuaibin Chang, Yunzhe Li, Anna Novoseltseva, Sunni Lin, Yicun Wu, Jiahui Zhu, Ann C. McKee, Douglas L. Rosene, Hui Wang, Irving J. Bigio, David A. Boas, Lei Tian

“…Abstract A major challenge in neuroscience is visualizing the structure of the human brain at different scales. Traditional histology reveals micro- and meso-scale brain features but suffers from staining variability, tissue damage, and distortion, which impedes accurate 3D reconstructions. …”
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Sex-based differences in the long-term fate of hippocampal neurons born after a traumatic brain injury by Hannah C. Downing, Hannah C. Downing, Ashley B. Glover, Jessica E. Gebhardt, Jessica E. Gebhardt, Katherine L. Thompson, Kathryn E. Saatman, Kathryn E. Saatman, Kathryn E. Saatman

“…IntroductionModerate-to-severe traumatic brain injury (TBI) results in an early loss of immature hippocampal granule cells and the activation of typically quiescent neural stem cells (NSCs) in the dentate gyrus. …”
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Effect of β-blocker on clinical outcomes in patients with traumatic brain injury: a retrospective propensity-matched study by Yaxin Zhang, Tingting Liu, Wenwen Ji, Guangdong Wang

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Air pollution exposures in early life and brain development in children (ABC): protocol for a pregnancy cohort study by John Kinuthia, R Scott McClelland, Barbra A Richardson, Elizabeth Maleche-Obimbo, Brent R Collett, Sarah Benki-Nugent, Faridah H Were, Anne M Riederer, Michael Gatari, CJ Karr, Edmund YW Seto, Beatrice C Mutai, Susan Wamithi, Priscilla Wanini Edemba, Timothy V Larson, Julian D Marshall

“…Longitudinal pregnancy cohort studies are optimal for individual exposure assessment during critical windows of brain development and examination of neurodevelopment. …”
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Electroacupuncture Regulates Disorders of Gut-Brain Interaction by Decreasing Corticotropin-Releasing Factor in a Rat Model of IBS by Ying Chen, Yan Zhao, Dan-ni Luo, Hui Zheng, Ying Li, Si-yuan Zhou

“…We aim to explore the mechanism of electroacupuncture (EA) in the dual regulation of disorders of gut-brain interaction. Methods. A rat model of IBS was generated by chronic unpredictable mild stress (CUMS). …”
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Cardiovascular risk burden, dementia risk and brain structural imaging markers: a study from UK Biobank by Ting Li, Jing Chen, Yan Zheng, Klodian Dhana, Geng Zong, Yuan Ma, Trudy Voortman, Wei Gan, Yaying Cao, Yonghua Hu, Changzheng Yuan, Jie Shen, Gaohong Zhu, Chengwu Feng

“…Background Cardiovascular risk burden is associated with dementia risk and neurodegeneration-related brain structure, while the role of genetics and incident cardiovascular disease (CVD) remains unclear.Aims To examine the association of overall cardiovascular risk burden with the risk of major dementia subtypes and volumes of related brain regions in a large sample, and to explore the role of genetics and CVD onset.Methods A prospective study among 354 654 participants free of CVD and dementia (2006–2010, mean age 56.4 years) was conducted within the UK Biobank, with brain magnetic resonance imaging (MRI) measurement available for 15 104 participants since 2014. …”
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Differed brain spontaneous neural activity between limb-onset and bulbar-onset amyotrophic lateral sclerosis patients by Si-Jie Chen, Qing-Yang Li, Jiang Zhou, Qian Wu, Yu Zhang, Qian-Qian Zhang, Hao Hu, Xiao-Quan Xu, Fei-Yun Wu, Qi Niu

“…Brain Research Bulletin…”
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Chronic Deep Brain Stimulation of the Hypothalamic Nucleus in Wistar Rats Alters Circulatory Levels of Corticosterone and Proinflammatory Cytokines by Juan Manuel Calleja-Castillo, Dora Luz De La Cruz-Aguilera, Joaquín Manjarrez, Marco Antonio Velasco-Velázquez, Gabriel Morales-Espinoza, Julia Moreno-Aguilar, Maria Eugenia Hernández, Lucinda Aguirre-Cruz, Lenin Pavón

“…Deep brain stimulation (DBS) is a therapeutic option for several diseases, but its effects on HPA axis activity and systemic inflammation are unknown. …”
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Growth Hormone Increases BDNF and mTOR Expression in Specific Brain Regions after Photothrombotic Stroke in Mice by Sonia Sanchez-Bezanilla, Daniel J. Beard, Rebecca J. Hood, N. David Åberg, Patricia Crock, Frederick R. Walker, Michael Nilsson, Jörgen Isgaard, Lin Kooi Ong

“…We aimed to explore the mechanisms of GH treatment by investigating how GH modulates pathways known to induce neuroplasticity, focusing on association between brain-derived neurotrophic factor (BDNF) and mammalian target of rapamycin (mTOR) in the peri-infarct area, hippocampus, and thalamus. …”
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Transcranial brain atlas based on photon measurement density function in a triple-parameter standard channel space by Lijiang Wei, Yang Zhao, Farui Liu, Yuanyuan Chen, Yilong Xu, Zheng Li, Chaozhe Zhu

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In vivo mapping of sodium homeostasis disturbances in individual ALS patients: A brain 23Na MRI study. by Aude-Marie Grapperon, Mohamed Mounir El Mendili, Adil Maarouf, Jean-Philippe Ranjeva, Maxime Guye, Annie Verschueren, Shahram Attarian, Wafaa Zaaraoui

“…In this study, we investigated disease severity at the individual level in ALS patients using brain 23Na MRI.<h4>Methods</h4>1H and 23Na brain MRI were collected prospectively from 28 ALS patients. …”
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Deep Brain Stimulation of Caudal Zona Incerta and Subthalamic Nucleus in Patients with Parkinson's Disease: Effects on Diadochokinetic Rate by Fredrik Karlsson, Elin Unger, Sofia Wahlgren, Patric Blomstedt, Jan Linder, Erik Nordh, Hamayun Zafar, Jan van Doorn

“…The hypokinetic dysarthria observed in Parkinson's disease (PD) affects the range, speed, and accuracy of articulatory gestures in patients, reducing the perceived quality of speech acoustic output in continuous speech. Deep brain stimulation (DBS) of the subthalamic nucleus (STN-DBS) and of the caudal zona incerta (cZi-DBS) are current surgical treatment options for PD. …”
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SAFIRE STRENGTH OPTIMIZATION: EFFECT ON TISSUE CONTRAST AND PATHOLOGICAL ASSESSMENT OF BRAIN MSCT WITH NON-HEMORRHAGE STROKE (SNH) by I Putu Eka Juliantara, Angel Lingkan Martoyo, Made Sayang Pratista

“…Purpose: Analyze the effect of variations in SAFIRE strength values on image contrast and pathological evaluation of CT scan brain with clinical Stroke Non-Hemorrhage (SNH). …”
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Doppler Impedance Changes at the Fetal Brain Vessels in a Pregnancy Affected with a Multiple Combination of Uteroplacental Anomalies by José Morales-Roselló, Núria Peralta Llorens

“…As the described uteroplacental anomalies determined a high risk of preterm delivery, due to cervical dilation, cord compresion, and placental haemorrhage, these fluctuating brain vascular changes might be the result of the fetal adaptation to the changes preceding an imminent delivery.…”
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Scutellarin Attenuates Hypertension-Induced Expression of Brain Toll-Like Receptor 4/Nuclear Factor Kappa B by Xingyong Chen, Xiaogeng Shi, Xu Zhang, Huixin Lei, Simei Long, Huanxing Su, Zhong Pei, Ruxun Huang

“…This study aimed to investigate the effects of scutellarin (administered by oral gavage daily for 2 weeks) on brain TLR4/nuclear factor kappa B-(NF-κB-) mediated inflammation and blood pressure in renovascular hypertensive (using the 2-kidney, 2-clip method) rats. …”
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Brain Stimulation Techniques in Research and Clinical Practice: A Comprehensive Review of Applications and Therapeutic Potential in Parkinson’s Disease by Ata Jahangir Moshayedi, Tahmineh Mokhtari, Mehran Emadi Andani

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